Antibiotic-modified Microbiome Might Be Responsible for Non-contagious World-wide Epidemics

Gábor Ternák

doi:doi:10.11648/j.bio.20190702.12

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Antibiotic-modified Microbiome Might Be Responsible for Non-contagious World-wide Epidemics

Gábor Ternák

Published in American Journal of Bioscience and Bioengineering (Volume 7, Issue 2)

Received: 5 March 2019 Accepted: 11 April 2019 Published: 9 May 2019

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Abstract

The rapid, pandemic-like, spread of certain noncontagious diseases (NCDs), like (childhood) obesity, type2 diabetes mellitus, particularly in children, autism, Alzheimer diseases, etc. prompted the researches to try to find appropriate explanation for this phenomenon. The well-known association between antibiotic enriched fodder and the weight gain of food animals, through the modification of the gut flora, clearly raises the possibility of similar relationship in human beings as well, which was described in several publications. The role of obesity in the development of diabetes is a well-known also. The antibiotic consumption pattern in the World clearly demonstrated the extensive utilization of the broad spectrum antibiotics, starting about three decades ago, and the appearance of still active degradation products in the environment, which might reenter into humans and animals again, and as the result of the alteration of human microbiome, could induce the pandemic-like NCDs. The yet to be explained rapid increase of prevalence of autism and Alzheimer diseases observed in the past three decades is alarming. According to a CDC survey, the prevalence of autism in the surveyed population was estimated as 16.8 per 1,000 (one in 59) children aged 8 years, which is considered as a 150% increase from the year 2000. The prevalence of Alzheimer’s disease in Europe was estimated at 5.05% (95% CI, 4.73-5.39). Microbiome alterations were observed in both cases and obesity is present in the 30% of autism as well. Putting together the mosaics from relevant publications, it might be concluded that we face the long term side effects of antibiotic consumption/pollution manifesting, through the alteration of microbioms as the pandemic appearance of certain NCDs. The restoration of the “normal” gut flora by fecal microbiota transfer (FMT) might be an option to influence those conditions.

Published in	American Journal of Bioscience and Bioengineering (Volume 7, Issue 2)
DOI	10.11648/j.bio.20190702.12
Page(s)	34-39
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Antibiotics, Microbiome, Type 2 Diabetes Mellitus (T2D), Obesity, Autism, Alzheimer Disease, Antibiotic Pollution, Fecal Microbiota Transfer (FMT)

References

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Gábor Ternák. (2019). Antibiotic-modified Microbiome Might Be Responsible for Non-contagious World-wide Epidemics. American Journal of Bioscience and Bioengineering, 7(2), 34-39. https://doi.org/10.11648/j.bio.20190702.12

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Gábor Ternák. Antibiotic-modified Microbiome Might Be Responsible for Non-contagious World-wide Epidemics. Am. J. BioSci. Bioeng. 2019, 7(2), 34-39. doi: 10.11648/j.bio.20190702.12

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Gábor Ternák. Antibiotic-modified Microbiome Might Be Responsible for Non-contagious World-wide Epidemics. Am J BioSci Bioeng. 2019;7(2):34-39. doi: 10.11648/j.bio.20190702.12

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@article{10.11648/j.bio.20190702.12,
  author = {Gábor Ternák},
  title = {Antibiotic-modified Microbiome Might Be Responsible for Non-contagious World-wide Epidemics},
  journal = {American Journal of Bioscience and Bioengineering},
  volume = {7},
  number = {2},
  pages = {34-39},
  doi = {10.11648/j.bio.20190702.12},
  url = {https://doi.org/10.11648/j.bio.20190702.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20190702.12},
  abstract = {The rapid, pandemic-like, spread of certain noncontagious diseases (NCDs), like (childhood) obesity, type2 diabetes mellitus, particularly in children, autism, Alzheimer diseases, etc. prompted the researches to try to find appropriate explanation for this phenomenon. The well-known association between antibiotic enriched fodder and the weight gain of food animals, through the modification of the gut flora, clearly raises the possibility of similar relationship in human beings as well, which was described in several publications. The role of obesity in the development of diabetes is a well-known also. The antibiotic consumption pattern in the World clearly demonstrated the extensive utilization of the broad spectrum antibiotics, starting about three decades ago, and the appearance of still active degradation products in the environment, which might reenter into humans and animals again, and as the result of the alteration of human microbiome, could induce the pandemic-like NCDs. The yet to be explained rapid increase of prevalence of autism and Alzheimer diseases observed in the past three decades is alarming. According to a CDC survey, the prevalence of autism in the surveyed population was estimated as 16.8 per 1,000 (one in 59) children aged 8 years, which is considered as a 150% increase from the year 2000. The prevalence of Alzheimer’s disease in Europe was estimated at 5.05% (95% CI, 4.73-5.39). Microbiome alterations were observed in both cases and obesity is present in the 30% of autism as well. Putting together the mosaics from relevant publications, it might be concluded that we face the long term side effects of antibiotic consumption/pollution manifesting, through the alteration of microbioms as the pandemic appearance of certain NCDs. The restoration of the “normal” gut flora by fecal microbiota transfer (FMT) might be an option to influence those conditions.},
 year = {2019}
}

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TY  - JOUR
T1  - Antibiotic-modified Microbiome Might Be Responsible for Non-contagious World-wide Epidemics
AU  - Gábor Ternák
Y1  - 2019/05/09
PY  - 2019
N1  - https://doi.org/10.11648/j.bio.20190702.12
DO  - 10.11648/j.bio.20190702.12
T2  - American Journal of Bioscience and Bioengineering
JF  - American Journal of Bioscience and Bioengineering
JO  - American Journal of Bioscience and Bioengineering
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PB  - Science Publishing Group
SN  - 2328-5893
UR  - https://doi.org/10.11648/j.bio.20190702.12
AB  - The rapid, pandemic-like, spread of certain noncontagious diseases (NCDs), like (childhood) obesity, type2 diabetes mellitus, particularly in children, autism, Alzheimer diseases, etc. prompted the researches to try to find appropriate explanation for this phenomenon. The well-known association between antibiotic enriched fodder and the weight gain of food animals, through the modification of the gut flora, clearly raises the possibility of similar relationship in human beings as well, which was described in several publications. The role of obesity in the development of diabetes is a well-known also. The antibiotic consumption pattern in the World clearly demonstrated the extensive utilization of the broad spectrum antibiotics, starting about three decades ago, and the appearance of still active degradation products in the environment, which might reenter into humans and animals again, and as the result of the alteration of human microbiome, could induce the pandemic-like NCDs. The yet to be explained rapid increase of prevalence of autism and Alzheimer diseases observed in the past three decades is alarming. According to a CDC survey, the prevalence of autism in the surveyed population was estimated as 16.8 per 1,000 (one in 59) children aged 8 years, which is considered as a 150% increase from the year 2000. The prevalence of Alzheimer’s disease in Europe was estimated at 5.05% (95% CI, 4.73-5.39). Microbiome alterations were observed in both cases and obesity is present in the 30% of autism as well. Putting together the mosaics from relevant publications, it might be concluded that we face the long term side effects of antibiotic consumption/pollution manifesting, through the alteration of microbioms as the pandemic appearance of certain NCDs. The restoration of the “normal” gut flora by fecal microbiota transfer (FMT) might be an option to influence those conditions.
VL  - 7
IS  - 2
ER  -

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Gábor Ternák

Chair of Migration Health, Faculty of Medicine, University of Pécs, Pécs, Hungary

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Gábor Ternák. (2019). Antibiotic-modified Microbiome Might Be Responsible for Non-contagious World-wide Epidemics. American Journal of Bioscience and Bioengineering, 7(2), 34-39. https://doi.org/10.11648/j.bio.20190702.12

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Gábor Ternák. Antibiotic-modified Microbiome Might Be Responsible for Non-contagious World-wide Epidemics. Am. J. BioSci. Bioeng. 2019, 7(2), 34-39. doi: 10.11648/j.bio.20190702.12

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AMA Style

Gábor Ternák. Antibiotic-modified Microbiome Might Be Responsible for Non-contagious World-wide Epidemics. Am J BioSci Bioeng. 2019;7(2):34-39. doi: 10.11648/j.bio.20190702.12

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@article{10.11648/j.bio.20190702.12,
  author = {Gábor Ternák},
  title = {Antibiotic-modified Microbiome Might Be Responsible for Non-contagious World-wide Epidemics},
  journal = {American Journal of Bioscience and Bioengineering},
  volume = {7},
  number = {2},
  pages = {34-39},
  doi = {10.11648/j.bio.20190702.12},
  url = {https://doi.org/10.11648/j.bio.20190702.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20190702.12},
  abstract = {The rapid, pandemic-like, spread of certain noncontagious diseases (NCDs), like (childhood) obesity, type2 diabetes mellitus, particularly in children, autism, Alzheimer diseases, etc. prompted the researches to try to find appropriate explanation for this phenomenon. The well-known association between antibiotic enriched fodder and the weight gain of food animals, through the modification of the gut flora, clearly raises the possibility of similar relationship in human beings as well, which was described in several publications. The role of obesity in the development of diabetes is a well-known also. The antibiotic consumption pattern in the World clearly demonstrated the extensive utilization of the broad spectrum antibiotics, starting about three decades ago, and the appearance of still active degradation products in the environment, which might reenter into humans and animals again, and as the result of the alteration of human microbiome, could induce the pandemic-like NCDs. The yet to be explained rapid increase of prevalence of autism and Alzheimer diseases observed in the past three decades is alarming. According to a CDC survey, the prevalence of autism in the surveyed population was estimated as 16.8 per 1,000 (one in 59) children aged 8 years, which is considered as a 150% increase from the year 2000. The prevalence of Alzheimer’s disease in Europe was estimated at 5.05% (95% CI, 4.73-5.39). Microbiome alterations were observed in both cases and obesity is present in the 30% of autism as well. Putting together the mosaics from relevant publications, it might be concluded that we face the long term side effects of antibiotic consumption/pollution manifesting, through the alteration of microbioms as the pandemic appearance of certain NCDs. The restoration of the “normal” gut flora by fecal microbiota transfer (FMT) might be an option to influence those conditions.},
 year = {2019}
}

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TY  - JOUR
T1  - Antibiotic-modified Microbiome Might Be Responsible for Non-contagious World-wide Epidemics
AU  - Gábor Ternák
Y1  - 2019/05/09
PY  - 2019
N1  - https://doi.org/10.11648/j.bio.20190702.12
DO  - 10.11648/j.bio.20190702.12
T2  - American Journal of Bioscience and Bioengineering
JF  - American Journal of Bioscience and Bioengineering
JO  - American Journal of Bioscience and Bioengineering
SP  - 34
EP  - 39
PB  - Science Publishing Group
SN  - 2328-5893
UR  - https://doi.org/10.11648/j.bio.20190702.12
AB  - The rapid, pandemic-like, spread of certain noncontagious diseases (NCDs), like (childhood) obesity, type2 diabetes mellitus, particularly in children, autism, Alzheimer diseases, etc. prompted the researches to try to find appropriate explanation for this phenomenon. The well-known association between antibiotic enriched fodder and the weight gain of food animals, through the modification of the gut flora, clearly raises the possibility of similar relationship in human beings as well, which was described in several publications. The role of obesity in the development of diabetes is a well-known also. The antibiotic consumption pattern in the World clearly demonstrated the extensive utilization of the broad spectrum antibiotics, starting about three decades ago, and the appearance of still active degradation products in the environment, which might reenter into humans and animals again, and as the result of the alteration of human microbiome, could induce the pandemic-like NCDs. The yet to be explained rapid increase of prevalence of autism and Alzheimer diseases observed in the past three decades is alarming. According to a CDC survey, the prevalence of autism in the surveyed population was estimated as 16.8 per 1,000 (one in 59) children aged 8 years, which is considered as a 150% increase from the year 2000. The prevalence of Alzheimer’s disease in Europe was estimated at 5.05% (95% CI, 4.73-5.39). Microbiome alterations were observed in both cases and obesity is present in the 30% of autism as well. Putting together the mosaics from relevant publications, it might be concluded that we face the long term side effects of antibiotic consumption/pollution manifesting, through the alteration of microbioms as the pandemic appearance of certain NCDs. The restoration of the “normal” gut flora by fecal microbiota transfer (FMT) might be an option to influence those conditions.
VL  - 7
IS  - 2
ER  -

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