Complicated Effect of He-Ne Laser Therapy on Pro-/Anti-Inflammatory Cytokines from Serum in Rats

Wuren Ma; Yunpeng Fan; Jinyang Zuo; Zhao Chen; Jun Yuan; Xiaoping Song

doi:doi:10.11648/j.avs.20180605.14

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Complicated Effect of He-Ne Laser Therapy on Pro-/Anti-Inflammatory Cytokines from Serum in Rats

Wuren Ma, Yunpeng Fan, Jinyang Zuo, Zhao Chen, Jun Yuan, Xiaoping Song

Published in Animal and Veterinary Sciences (Volume 6, Issue 5)

Received: 23 October 2018 Accepted: 9 November 2018 Published: 5 December 2018

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Abstract

Helium-neon (He-Ne) laser is one of the most common low energy lasers used in physiotherapy for promoting wound healing. This study was about to investigate the effects of He-Ne laser therapy on the pro-/anti-inflammatory cytokines in rats up to 10 days of treatment. 16 non-pregnant female rats were divided into 4 groups randomly, 4 rats in each group. They are negative control (NC) group, positive control (PC) group, laser treatment (LA) group and erythromycin ointment (ER) treatment group. The LA group was treated with 25 mW of He-Ne laser for 30 min every day for 10 days, with 632.8 nm of wavelength immediately after three incisions were made on the mid-dorsal line of each rat. The results showed that He-Ne laser therapy could decrease the level of IL-1β compared with the PC and ER groups; while increase the level of IL-6 compared with the NC and ER groups, and the level of TNF-α compared with the PC and ER group. He-Ne laser therapy also increased the concentration of IL-10 compared with the other three groups, and the concentration of TGF-β compared with the NC and ER groups. These results indicated that laser acupuncture increased the production of IL-6, IL-10, TGF-β and TNF-α after 10 days of treatment, which was the proliferation stage of wound healing process, and the effect of He-Ne laser therapy on pro-inflammatory cytokines was not always consistent, which might be time-dependent of He-Ne laser treatment.

Published in	Animal and Veterinary Sciences (Volume 6, Issue 5)
DOI	10.11648/j.avs.20180605.14
Page(s)	88-94
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

He-Ne Laser Therapy, Pro-inflammatory Cytokines, Anti-inflammatory Cytokines, Wound Healing

References

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APA Style

Wuren Ma, Yunpeng Fan, Jinyang Zuo, Zhao Chen, Jun Yuan, et al. (2018). Complicated Effect of He-Ne Laser Therapy on Pro-/Anti-Inflammatory Cytokines from Serum in Rats. Animal and Veterinary Sciences, 6(5), 88-94. https://doi.org/10.11648/j.avs.20180605.14

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ACS Style

Wuren Ma; Yunpeng Fan; Jinyang Zuo; Zhao Chen; Jun Yuan, et al. Complicated Effect of He-Ne Laser Therapy on Pro-/Anti-Inflammatory Cytokines from Serum in Rats. Anim. Vet. Sci. 2018, 6(5), 88-94. doi: 10.11648/j.avs.20180605.14

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AMA Style

Wuren Ma, Yunpeng Fan, Jinyang Zuo, Zhao Chen, Jun Yuan, et al. Complicated Effect of He-Ne Laser Therapy on Pro-/Anti-Inflammatory Cytokines from Serum in Rats. Anim Vet Sci. 2018;6(5):88-94. doi: 10.11648/j.avs.20180605.14

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@article{10.11648/j.avs.20180605.14,
  author = {Wuren Ma and Yunpeng Fan and Jinyang Zuo and Zhao Chen and Jun Yuan and Xiaoping Song},
  title = {Complicated Effect of He-Ne Laser Therapy on Pro-/Anti-Inflammatory Cytokines from Serum in Rats},
  journal = {Animal and Veterinary Sciences},
  volume = {6},
  number = {5},
  pages = {88-94},
  doi = {10.11648/j.avs.20180605.14},
  url = {https://doi.org/10.11648/j.avs.20180605.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20180605.14},
  abstract = {Helium-neon (He-Ne) laser is one of the most common low energy lasers used in physiotherapy for promoting wound healing. This study was about to investigate the effects of He-Ne laser therapy on the pro-/anti-inflammatory cytokines in rats up to 10 days of treatment. 16 non-pregnant female rats were divided into 4 groups randomly, 4 rats in each group. They are negative control (NC) group, positive control (PC) group, laser treatment (LA) group and erythromycin ointment (ER) treatment group. The LA group was treated with 25 mW of He-Ne laser for 30 min every day for 10 days, with 632.8 nm of wavelength immediately after three incisions were made on the mid-dorsal line of each rat. The results showed that He-Ne laser therapy could decrease the level of IL-1β compared with the PC and ER groups; while increase the level of IL-6 compared with the NC and ER groups, and the level of TNF-α compared with the PC and ER group. He-Ne laser therapy also increased the concentration of IL-10 compared with the other three groups, and the concentration of TGF-β compared with the NC and ER groups. These results indicated that laser acupuncture increased the production of IL-6, IL-10, TGF-β and TNF-α after 10 days of treatment, which was the proliferation stage of wound healing process, and the effect of He-Ne laser therapy on pro-inflammatory cytokines was not always consistent, which might be time-dependent of He-Ne laser treatment.},
 year = {2018}
}

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TY  - JOUR
T1  - Complicated Effect of He-Ne Laser Therapy on Pro-/Anti-Inflammatory Cytokines from Serum in Rats
AU  - Wuren Ma
AU  - Yunpeng Fan
AU  - Jinyang Zuo
AU  - Zhao Chen
AU  - Jun Yuan
AU  - Xiaoping Song
Y1  - 2018/12/05
PY  - 2018
N1  - https://doi.org/10.11648/j.avs.20180605.14
DO  - 10.11648/j.avs.20180605.14
T2  - Animal and Veterinary Sciences
JF  - Animal and Veterinary Sciences
JO  - Animal and Veterinary Sciences
SP  - 88
EP  - 94
PB  - Science Publishing Group
SN  - 2328-5850
UR  - https://doi.org/10.11648/j.avs.20180605.14
AB  - Helium-neon (He-Ne) laser is one of the most common low energy lasers used in physiotherapy for promoting wound healing. This study was about to investigate the effects of He-Ne laser therapy on the pro-/anti-inflammatory cytokines in rats up to 10 days of treatment. 16 non-pregnant female rats were divided into 4 groups randomly, 4 rats in each group. They are negative control (NC) group, positive control (PC) group, laser treatment (LA) group and erythromycin ointment (ER) treatment group. The LA group was treated with 25 mW of He-Ne laser for 30 min every day for 10 days, with 632.8 nm of wavelength immediately after three incisions were made on the mid-dorsal line of each rat. The results showed that He-Ne laser therapy could decrease the level of IL-1β compared with the PC and ER groups; while increase the level of IL-6 compared with the NC and ER groups, and the level of TNF-α compared with the PC and ER group. He-Ne laser therapy also increased the concentration of IL-10 compared with the other three groups, and the concentration of TGF-β compared with the NC and ER groups. These results indicated that laser acupuncture increased the production of IL-6, IL-10, TGF-β and TNF-α after 10 days of treatment, which was the proliferation stage of wound healing process, and the effect of He-Ne laser therapy on pro-inflammatory cytokines was not always consistent, which might be time-dependent of He-Ne laser treatment.
VL  - 6
IS  - 5
ER  -

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Author Information

Wuren Ma

College of Veterinary Medicine, Northwest A&F University, Yangling, P R China
Yunpeng Fan

College of Veterinary Medicine, Northwest A&F University, Yangling, P R China
Jinyang Zuo

College of Veterinary Medicine, Northwest A&F University, Yangling, P R China
Zhao Chen

College of Veterinary Medicine, Northwest A&F University, Yangling, P R China
Jun Yuan

Institute of Fisheries Engineering, Chinese Academy of Fishery Sciences, Beijing, P R China
Xiaoping Song

College of Veterinary Medicine, Northwest A&F University, Yangling, P R China

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APA Style

Wuren Ma, Yunpeng Fan, Jinyang Zuo, Zhao Chen, Jun Yuan, et al. (2018). Complicated Effect of He-Ne Laser Therapy on Pro-/Anti-Inflammatory Cytokines from Serum in Rats. Animal and Veterinary Sciences, 6(5), 88-94. https://doi.org/10.11648/j.avs.20180605.14

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ACS Style

Wuren Ma; Yunpeng Fan; Jinyang Zuo; Zhao Chen; Jun Yuan, et al. Complicated Effect of He-Ne Laser Therapy on Pro-/Anti-Inflammatory Cytokines from Serum in Rats. Anim. Vet. Sci. 2018, 6(5), 88-94. doi: 10.11648/j.avs.20180605.14

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AMA Style

Wuren Ma, Yunpeng Fan, Jinyang Zuo, Zhao Chen, Jun Yuan, et al. Complicated Effect of He-Ne Laser Therapy on Pro-/Anti-Inflammatory Cytokines from Serum in Rats. Anim Vet Sci. 2018;6(5):88-94. doi: 10.11648/j.avs.20180605.14

Copy | Download

@article{10.11648/j.avs.20180605.14,
  author = {Wuren Ma and Yunpeng Fan and Jinyang Zuo and Zhao Chen and Jun Yuan and Xiaoping Song},
  title = {Complicated Effect of He-Ne Laser Therapy on Pro-/Anti-Inflammatory Cytokines from Serum in Rats},
  journal = {Animal and Veterinary Sciences},
  volume = {6},
  number = {5},
  pages = {88-94},
  doi = {10.11648/j.avs.20180605.14},
  url = {https://doi.org/10.11648/j.avs.20180605.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20180605.14},
  abstract = {Helium-neon (He-Ne) laser is one of the most common low energy lasers used in physiotherapy for promoting wound healing. This study was about to investigate the effects of He-Ne laser therapy on the pro-/anti-inflammatory cytokines in rats up to 10 days of treatment. 16 non-pregnant female rats were divided into 4 groups randomly, 4 rats in each group. They are negative control (NC) group, positive control (PC) group, laser treatment (LA) group and erythromycin ointment (ER) treatment group. The LA group was treated with 25 mW of He-Ne laser for 30 min every day for 10 days, with 632.8 nm of wavelength immediately after three incisions were made on the mid-dorsal line of each rat. The results showed that He-Ne laser therapy could decrease the level of IL-1β compared with the PC and ER groups; while increase the level of IL-6 compared with the NC and ER groups, and the level of TNF-α compared with the PC and ER group. He-Ne laser therapy also increased the concentration of IL-10 compared with the other three groups, and the concentration of TGF-β compared with the NC and ER groups. These results indicated that laser acupuncture increased the production of IL-6, IL-10, TGF-β and TNF-α after 10 days of treatment, which was the proliferation stage of wound healing process, and the effect of He-Ne laser therapy on pro-inflammatory cytokines was not always consistent, which might be time-dependent of He-Ne laser treatment.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Complicated Effect of He-Ne Laser Therapy on Pro-/Anti-Inflammatory Cytokines from Serum in Rats
AU  - Wuren Ma
AU  - Yunpeng Fan
AU  - Jinyang Zuo
AU  - Zhao Chen
AU  - Jun Yuan
AU  - Xiaoping Song
Y1  - 2018/12/05
PY  - 2018
N1  - https://doi.org/10.11648/j.avs.20180605.14
DO  - 10.11648/j.avs.20180605.14
T2  - Animal and Veterinary Sciences
JF  - Animal and Veterinary Sciences
JO  - Animal and Veterinary Sciences
SP  - 88
EP  - 94
PB  - Science Publishing Group
SN  - 2328-5850
UR  - https://doi.org/10.11648/j.avs.20180605.14
AB  - Helium-neon (He-Ne) laser is one of the most common low energy lasers used in physiotherapy for promoting wound healing. This study was about to investigate the effects of He-Ne laser therapy on the pro-/anti-inflammatory cytokines in rats up to 10 days of treatment. 16 non-pregnant female rats were divided into 4 groups randomly, 4 rats in each group. They are negative control (NC) group, positive control (PC) group, laser treatment (LA) group and erythromycin ointment (ER) treatment group. The LA group was treated with 25 mW of He-Ne laser for 30 min every day for 10 days, with 632.8 nm of wavelength immediately after three incisions were made on the mid-dorsal line of each rat. The results showed that He-Ne laser therapy could decrease the level of IL-1β compared with the PC and ER groups; while increase the level of IL-6 compared with the NC and ER groups, and the level of TNF-α compared with the PC and ER group. He-Ne laser therapy also increased the concentration of IL-10 compared with the other three groups, and the concentration of TGF-β compared with the NC and ER groups. These results indicated that laser acupuncture increased the production of IL-6, IL-10, TGF-β and TNF-α after 10 days of treatment, which was the proliferation stage of wound healing process, and the effect of He-Ne laser therapy on pro-inflammatory cytokines was not always consistent, which might be time-dependent of He-Ne laser treatment.
VL  - 6
IS  - 5
ER  -

Copy | Download