There are limited data on the assessment biochemical and hematological profile in the CRF (CRF) of before and after hemodialysis in the Gaza Strip. The study aimed to evaluating some biochemical parameters and hematological profile in the CRF of before and after hemodialysis at Martyr Mohammed El-Najjar Hospital in Rafah, Gaza Strip, Palestine. Forty-three (end-stage renal disease) ESRD patients, aged 20-70 years old who were referred to Martyr Mohammed Youssef Al-Najjar Hospital in Rafah for the hemodialysis department. 43 apparently healthy individuals matched for ages were used as a control group for comparisons. The results showed that after-dialysis higher statistically significant in Hb, RBC, HCT, PLT, AST, ALT, ALP and Ca level than before-dialysis. While Ph, WBC, RDW, creatinine (Cr.), Urea was lower statistically significant in after hemodialysis than before-dialysis (P < 0.05). theses indicate to: chronic kidney disease shows abnormal hematological parameters, precisely reduced levels of RBC count, hemoglobin, hematocrit, and platelet count, in addition, before-dialysis patients are more anemic and thrombocytopenic than after-dialysis patients and this is may indicate of lack of blood pressure and type2 diabetes mellites (T2DM) control in these patients. AST& ALT activities vary in concentration before and after hemodialysis and make the after-dialysis patients are higher than before-dialysis.
| Published in | American Journal of Laboratory Medicine (Volume 6, Issue 1) |
| DOI | 10.11648/j.ajlm.20210601.12 |
| Page(s) | 8-16 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2021. Published by Science Publishing Group |
Biochemical Parameters, Hematological Profile, CRF, Martyr Mohammed El-Najjar Hospital, Rafah, Gaza Strip, Palestine
| [1] | Yang, F., Zhang, L., Wu, H., Zou, H., & Du, Y. (2014). Clinical analysis of cause, treatment and prognosis in acute kidney injury patients. PLoS One, 9 (2), e85214. |
| [2] | Santoro, D., Caccamo, D., Lucisano, S., Buemi, M., Sebekova, K., Teta, D., & De Nicola, L. (2015). Interplay of vitamin D, erythropoiesis, and the renin-angiotensin system. BioMed research international, 2015. |
| [3] | Alexander, R. T., Hemmelgarn, B. R., Wiebe, N., Bello, A., Morgan, C., Samuel, S., & Tonelli, M. (2012). Kidney stones and kidney function loss: a cohort study. Bmj, 345, e5287. |
| [4] | Bindroo, S., & Challa, H. J. Review from StatPearls Publishing, Treasure Island (FL), 08 Aug 2018. |
| [5] | de Francisco, A. L. M. (2010). Future directions in therapy for chronic kidney disease. Nefrología (English Edition), 30 (1), 1-9. |
| [6] | Vadakedath, S., & Kandi, V. (2017). Dialysis: a review of the mechanisms underlying complications in the management of CRF. Cureus, 9 (8). |
| [7] | Islam, M. N., Ferdous, A., Zahid, A. Z., Alam, M., & Islam, M. N. (2015). Haematological profile of patients with chronic kidney disease in Northern Bangladesh. Dinajpur Med Col J, 8 (1), 21-7. |
| [8] | Amin, N., Mahmood, R. T., Asad, M. J., Zafar, M., & Raja, A. M. (2014). Evaluating urea and Cr levels in CRF before and after dialysis: a prospective study. Journal of cardiovascular disease, 2 (2), 1-4. |
| [9] | Maduell, F., Rodriguez, N., Rodríguez, N., Arias Guillén, M., Arias-Guillén, M., Jimenez, S.,... & Fontseré, N. (2012). Dialysate calcium individualisation: a pending issue. Nefrología (English Edition), 32 (5), 579-586. |
| [10] | Bech, A., Reichert, L., Telting, D., & de Boer, H. (2013). Assessment of calcium balance in patients on hemodialysis, based on ionized calcium and parathyroid hormone responses. J Nephrol, 26 (5), 925-930. |
| [11] | Kendrick, J. and M. Chonchol (2011). "The role of phosphorus in the development and progression of vascular calcification." American Journal of Kidney Diseases 58 (5): 826-834. |
| [12] | Tomás, I., Marinho, J. S., Limeres, J., Santos, M. J., Araújo, L., & Diz, P. (2008). Changes in salivary composition in patients with renal failure. archives of oral biology, 53 (6), 528-532. |
| [13] | Meenakshi, G. (2016). "Effect of hemodialysis on certain biochemical parameters in CRF patients." International Journal of Contemporary Medical Research 3 (10): 2869-2871. |
| [14] | Ahmad, S., Misra, M., Hoenich, N., & Daugirdas, J. (2008). HD Apparatus en Handbook of Dialysis. |
| [15] | Shankalia, D. and A. Tanna (2013). "Role of HD in renal failure to correct biochemical parameters." Indian J Appl Res 3 (6): 414-416. |
| [16] | Khaled M. D., A. F., A. T. Abdelgader, S. Bioprabhu. (2015). "effect of haemodialysis on some metabolic products of ckd patients in Libya." 4 (12): 45-54. |
| [17] | Chielle, E. O., Rigon, K. A., Arcari, I. A., Stein, V., & Santos, G. A. D. (2015). Influence of HD on the plasma concentration of adenosine deaminase in patients with chronic kidney disease. Jornal Brasileiro de Patologia e Medicina Laboratorial, 51 (3), 153-157. |
| [18] | Montini, G., Pisanello, L., Testa, S., Daccò, V., Strologo, L. D., Taioli, E.,... & Ardissino, G. (2003). Urea percentiles in children with CRF. Pediatric Nephrology, 18 (3), 261-265. |
| [19] | Mohammed-Jumaah, I. A. (2013). "A study of some biochemical parameters in blood serum of patients with CRF." Journal of Basrah Researches (Sciences) 39 (4A): 20-32. |
| [20] | Mahomoodally, M. F., & Nugessur, H. (2014). before-and after-Dialysis Correla ons of Serum α-Amylase, Crea nine and Urea in CRF Pa ents. Journal of Medical Research and Development (JMRD), 151-60. |
| [21] | Mustafa, G., Khan, I. U. K. M. K., & Sualeh, M. (2010). Antioxidant level in normal and dialyzed patients using FRAP method. Pakistan journal of pharmaceutical sciences, 23 (2). |
| [22] | Babekr, A. A. S. (2015). The Effect of HD on Alanine Transaminase And Aspartate transaminase (ALT&AST) levels in Patients with Renal Failure, Sudan University of Science and Technology. |
| [23] | Sette, L. H. B. C. and E. P. de Almeida Lopes (2014). "Liver enzymes serum levels in patients with chronic kidney disease on hemodialysis: a comprehensive review." Clinics 69 (4): 271-278. |
| [24] | Shittu, M. O., Adelakun, A., Eegunjobi, A., Idowu, O., & Shittu, B. T. (2014). Analysis of aminotransferases in predialysis chronic kidney disease patients. IOSR J. Dent. Med. Sci, 13, 87-89. |
| [25] | Latiwesh, O. B., Younis, M. Y., Shakila, S., Abdulmalik, F., Alammari, J. A., Min, Y.,... & Peela, J. R. (2018). Hepatic enzymes changes in chronic kidney disease patients-a need for modified reference values. journal of evolution of medical and dental sciences-jemds, 7 (16), 1949-1954. |
| [26] | Abate, A., Birhan, W., & Alemu, A. (2013). Association of anemia and renal function test among diabetes mellitus patients attending Fenote Selam Hospital, West Gojam, Northwest Ethiopia: a cross sectional study. BMC Blood Disorders, 13 (1), 6. |
| [27] | Afshar, R., Sanavi, S., Salimi, J., & Ahmadzadeh, M. (2010). Hematological profile of chronic kidney disease (CKD) patients in Iran, in pre-dialysis stages and after initiation of hemodialysis. Saudi Journal of Kidney Diseases and Transplantation, 21 (2), 368. |
| [28] | Latiweshob, O. B., Elwerfaly, H. H., & Sheriff, D. S. (2017). Haematological changes in predialyzed and hemodialyzed chronic kidney disease patients in libya. IOSR J of Dental and Med Sciences, 16, 106-12. |
| [29] | Alghythan, A. K. and A. H. Alsaeed (2012). "Hematological changes before and after hemodialysis." Scientific Research and Essays 7 (4): 490-497. |
| [30] | Walts., R. (2004). "Neutropenia. Wintrobe's Clinical Hematology 11th edition." Philadelphia, Lippincott Williams & Wilkins 2 (63): 1748. |
| [31] | Bat, T., Bat, B. E., El‐Moghraby, A., Patel, S., Feng, X., Dunbar, C. E., & Sarac, E. (2016). Thrombopoietic status of patients on haemodialysis. British journal of haematology, 172 (6), 954-957. |
| [32] | Dorgalaleh, A., Mahmudi, M., Tabibian, S., Khatib, Z. K., Tamaddon, G. H., Moghaddam, E. S.,... & Moradi, E. (2013). Anemia and thrombocytopenia in acute and CRF. International journal of hematology-oncology and stem cell research, 7 (4), 34. |
APA Style
Mohamad Alhamss, Ahmad Tabash, Abdrabbou Elregeb, Ayman Abu Mustafa, Asmaa Hejazi, et al. (2021). Assessment of Biochemical and Hematological Parameters in the CRF of Before and After Hemodialysis at Martyr Mohammed El-Najjar Hospital in Gaza Strip, Palestine. American Journal of Laboratory Medicine, 6(1), 8-16. https://doi.org/10.11648/j.ajlm.20210601.12
ACS Style
Mohamad Alhamss; Ahmad Tabash; Abdrabbou Elregeb; Ayman Abu Mustafa; Asmaa Hejazi, et al. Assessment of Biochemical and Hematological Parameters in the CRF of Before and After Hemodialysis at Martyr Mohammed El-Najjar Hospital in Gaza Strip, Palestine. Am. J. Lab. Med. 2021, 6(1), 8-16. doi: 10.11648/j.ajlm.20210601.12
AMA Style
Mohamad Alhamss, Ahmad Tabash, Abdrabbou Elregeb, Ayman Abu Mustafa, Asmaa Hejazi, et al. Assessment of Biochemical and Hematological Parameters in the CRF of Before and After Hemodialysis at Martyr Mohammed El-Najjar Hospital in Gaza Strip, Palestine. Am J Lab Med. 2021;6(1):8-16. doi: 10.11648/j.ajlm.20210601.12
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.ajlm.20210601.12,
author = {Mohamad Alhamss and Ahmad Tabash and Abdrabbou Elregeb and Ayman Abu Mustafa and Asmaa Hejazi and Riyad Shaban and Ramy Sarafandi and Yaser Elarja and Nedal Hasanain and Shawgy Elhessy and Faten Allyan},
title = {Assessment of Biochemical and Hematological Parameters in the CRF of Before and After Hemodialysis at Martyr Mohammed El-Najjar Hospital in Gaza Strip, Palestine},
journal = {American Journal of Laboratory Medicine},
volume = {6},
number = {1},
pages = {8-16},
doi = {10.11648/j.ajlm.20210601.12},
url = {https://doi.org/10.11648/j.ajlm.20210601.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20210601.12},
abstract = {There are limited data on the assessment biochemical and hematological profile in the CRF (CRF) of before and after hemodialysis in the Gaza Strip. The study aimed to evaluating some biochemical parameters and hematological profile in the CRF of before and after hemodialysis at Martyr Mohammed El-Najjar Hospital in Rafah, Gaza Strip, Palestine. Forty-three (end-stage renal disease) ESRD patients, aged 20-70 years old who were referred to Martyr Mohammed Youssef Al-Najjar Hospital in Rafah for the hemodialysis department. 43 apparently healthy individuals matched for ages were used as a control group for comparisons. The results showed that after-dialysis higher statistically significant in Hb, RBC, HCT, PLT, AST, ALT, ALP and Ca level than before-dialysis. While Ph, WBC, RDW, creatinine (Cr.), Urea was lower statistically significant in after hemodialysis than before-dialysis (P < 0.05). theses indicate to: chronic kidney disease shows abnormal hematological parameters, precisely reduced levels of RBC count, hemoglobin, hematocrit, and platelet count, in addition, before-dialysis patients are more anemic and thrombocytopenic than after-dialysis patients and this is may indicate of lack of blood pressure and type2 diabetes mellites (T2DM) control in these patients. AST& ALT activities vary in concentration before and after hemodialysis and make the after-dialysis patients are higher than before-dialysis.},
year = {2021}
}
TY - JOUR T1 - Assessment of Biochemical and Hematological Parameters in the CRF of Before and After Hemodialysis at Martyr Mohammed El-Najjar Hospital in Gaza Strip, Palestine AU - Mohamad Alhamss AU - Ahmad Tabash AU - Abdrabbou Elregeb AU - Ayman Abu Mustafa AU - Asmaa Hejazi AU - Riyad Shaban AU - Ramy Sarafandi AU - Yaser Elarja AU - Nedal Hasanain AU - Shawgy Elhessy AU - Faten Allyan Y1 - 2021/03/12 PY - 2021 N1 - https://doi.org/10.11648/j.ajlm.20210601.12 DO - 10.11648/j.ajlm.20210601.12 T2 - American Journal of Laboratory Medicine JF - American Journal of Laboratory Medicine JO - American Journal of Laboratory Medicine SP - 8 EP - 16 PB - Science Publishing Group SN - 2575-386X UR - https://doi.org/10.11648/j.ajlm.20210601.12 AB - There are limited data on the assessment biochemical and hematological profile in the CRF (CRF) of before and after hemodialysis in the Gaza Strip. The study aimed to evaluating some biochemical parameters and hematological profile in the CRF of before and after hemodialysis at Martyr Mohammed El-Najjar Hospital in Rafah, Gaza Strip, Palestine. Forty-three (end-stage renal disease) ESRD patients, aged 20-70 years old who were referred to Martyr Mohammed Youssef Al-Najjar Hospital in Rafah for the hemodialysis department. 43 apparently healthy individuals matched for ages were used as a control group for comparisons. The results showed that after-dialysis higher statistically significant in Hb, RBC, HCT, PLT, AST, ALT, ALP and Ca level than before-dialysis. While Ph, WBC, RDW, creatinine (Cr.), Urea was lower statistically significant in after hemodialysis than before-dialysis (P < 0.05). theses indicate to: chronic kidney disease shows abnormal hematological parameters, precisely reduced levels of RBC count, hemoglobin, hematocrit, and platelet count, in addition, before-dialysis patients are more anemic and thrombocytopenic than after-dialysis patients and this is may indicate of lack of blood pressure and type2 diabetes mellites (T2DM) control in these patients. AST& ALT activities vary in concentration before and after hemodialysis and make the after-dialysis patients are higher than before-dialysis. VL - 6 IS - 1 ER -
Information
Email: