Spectrum of Histopathological Diagnosis of Schistosomiasis as a Systemic Parasitic Infection in the North-West Nigeria

Abdullahi kabiru; Rasheed Mumini Wemimo; Mohammed Umar; Adegboye Adeyemi Taiwo; Afolayan Enoch Abiodun; Aliyu Salihu

doi:doi:10.11648/j.ajlm.20200506.15

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Spectrum of Histopathological Diagnosis of Schistosomiasis as a Systemic Parasitic Infection in the North-West Nigeria

Abdullahi kabiru, Rasheed Mumini Wemimo, Mohammed Umar, Adegboye Adeyemi Taiwo, Afolayan Enoch Abiodun, Aliyu Salihu

Published in American Journal of Laboratory Medicine (Volume 5, Issue 6)

Received: 12 June 2020 Accepted: 28 June 2020 Published: 31 December 2020

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Abstract

Introduction: Schistosomiasis is one of the neglected tropical diseases transmitted by freshwater snail in the slow-moving water of tropical rivers and ranks second among the most widespread parasitic disease in various nations in sub-Saharan Africa. Methodology: This is a 10-year retrospective study of all cases of schistosomiasis seen in the Department of Anatomic Pathology, Usmanu Danfodiyo University Teaching Sokoto between January 2008 and December 2017. All the cases of schistosomiasis diagnosed was retrieved from the surgical pathology register. The patients’ biodata and symptoms was retrieved from patients’ folder. The specimens were processed with 10% Neutral buffered formalin, stained with Haematoxylin and Eosin and reported by the pathologist at the study centre. The 2016 WHO classification of the urinary system and male genital organs were used to classify the tumours. Results: A hundred and fifty-nine patients were analysed with schistosomiasis of varying systems range from gastrointestinal, prostate, genitourinary and 38 cases of malignancies of the urinary bladder with associated schistosomiasis and prostate. In the gastrointestinal system, the appendiceal schistosomiasis accounted for 21(80.8%), rectum 3 (11.5%) and sigmoid colon 2 cases (7.7%). Benign prostatic hyperplasia with schistosomiasis accounted for 1 case (25.0%) while 3 cases (75.0%) of prostatic adenocarcinoma with schistosomiasis showed age range of 45 to 78 years. There are one hundred and eleven (111) cases of urinary bladder schistosomiasis which accounted for 86.0%, male to female ratio of 10:1 and age range from 9.0 to 78.0 years. There are 27 cases of invasive squamous cell carcinoma of the urinary bladder associated with schistosomiasis accounted for 65.8% while adenocarcinoma showed 4 cases (9.7%). Moderately differentiated SCC accounted for the largest degree of tumour differentiation associated with schistosomiasis accounted for 69.6%. Terminal haematuria is the most common symptom of urinary bladder schistosomiasis accounted for 102 cases (64.2%), followed by suprapubic abdominal pain 52 (32.5%), weight loss 30 (18.9%) for patients with malignancy Conclusion: Schistosomiasis is a public health disease in endemic regions in African countries with proper documentation on the its pathogenesis, risk factors and effective treatment and complications if left untreated. Thus, mobilization of appropriate resources to help the vulnerable in order to reduce morbidity and mortalities is very crucial.

Published in	American Journal of Laboratory Medicine (Volume 5, Issue 6)
DOI	10.11648/j.ajlm.20200506.15
Page(s)	180-184
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Schistosomiasis, Adenocarcinoma, Squamous Cell Carcinoma (SCC), Benign Prostatic Hyperplasia, WHO

References

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Abdullahi kabiru, Rasheed Mumini Wemimo, Mohammed Umar, Adegboye Adeyemi Taiwo, Afolayan Enoch Abiodun, et al. (2020). Spectrum of Histopathological Diagnosis of Schistosomiasis as a Systemic Parasitic Infection in the North-West Nigeria. American Journal of Laboratory Medicine, 5(6), 180-184. https://doi.org/10.11648/j.ajlm.20200506.15

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ACS Style

Abdullahi kabiru; Rasheed Mumini Wemimo; Mohammed Umar; Adegboye Adeyemi Taiwo; Afolayan Enoch Abiodun, et al. Spectrum of Histopathological Diagnosis of Schistosomiasis as a Systemic Parasitic Infection in the North-West Nigeria. Am. J. Lab. Med. 2020, 5(6), 180-184. doi: 10.11648/j.ajlm.20200506.15

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AMA Style

Abdullahi kabiru, Rasheed Mumini Wemimo, Mohammed Umar, Adegboye Adeyemi Taiwo, Afolayan Enoch Abiodun, et al. Spectrum of Histopathological Diagnosis of Schistosomiasis as a Systemic Parasitic Infection in the North-West Nigeria. Am J Lab Med. 2020;5(6):180-184. doi: 10.11648/j.ajlm.20200506.15

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@article{10.11648/j.ajlm.20200506.15,
  author = {Abdullahi kabiru and Rasheed Mumini Wemimo and Mohammed Umar and Adegboye Adeyemi Taiwo and Afolayan Enoch Abiodun and Aliyu Salihu},
  title = {Spectrum of Histopathological Diagnosis of Schistosomiasis as a Systemic Parasitic Infection in the North-West Nigeria},
  journal = {American Journal of Laboratory Medicine},
  volume = {5},
  number = {6},
  pages = {180-184},
  doi = {10.11648/j.ajlm.20200506.15},
  url = {https://doi.org/10.11648/j.ajlm.20200506.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20200506.15},
  abstract = {Introduction: Schistosomiasis is one of the neglected tropical diseases transmitted by freshwater snail in the slow-moving water of tropical rivers and ranks second among the most widespread parasitic disease in various nations in sub-Saharan Africa. Methodology: This is a 10-year retrospective study of all cases of schistosomiasis seen in the Department of Anatomic Pathology, Usmanu Danfodiyo University Teaching Sokoto between January 2008 and December 2017. All the cases of schistosomiasis diagnosed was retrieved from the surgical pathology register. The patients’ biodata and symptoms was retrieved from patients’ folder. The specimens were processed with 10% Neutral buffered formalin, stained with Haematoxylin and Eosin and reported by the pathologist at the study centre. The 2016 WHO classification of the urinary system and male genital organs were used to classify the tumours. Results: A hundred and fifty-nine patients were analysed with schistosomiasis of varying systems range from gastrointestinal, prostate, genitourinary and 38 cases of malignancies of the urinary bladder with associated schistosomiasis and prostate. In the gastrointestinal system, the appendiceal schistosomiasis accounted for 21(80.8%), rectum 3 (11.5%) and sigmoid colon 2 cases (7.7%). Benign prostatic hyperplasia with schistosomiasis accounted for 1 case (25.0%) while 3 cases (75.0%) of prostatic adenocarcinoma with schistosomiasis showed age range of 45 to 78 years. There are one hundred and eleven (111) cases of urinary bladder schistosomiasis which accounted for 86.0%, male to female ratio of 10:1 and age range from 9.0 to 78.0 years. There are 27 cases of invasive squamous cell carcinoma of the urinary bladder associated with schistosomiasis accounted for 65.8% while adenocarcinoma showed 4 cases (9.7%). Moderately differentiated SCC accounted for the largest degree of tumour differentiation associated with schistosomiasis accounted for 69.6%. Terminal haematuria is the most common symptom of urinary bladder schistosomiasis accounted for 102 cases (64.2%), followed by suprapubic abdominal pain 52 (32.5%), weight loss 30 (18.9%) for patients with malignancy Conclusion: Schistosomiasis is a public health disease in endemic regions in African countries with proper documentation on the its pathogenesis, risk factors and effective treatment and complications if left untreated. Thus, mobilization of appropriate resources to help the vulnerable in order to reduce morbidity and mortalities is very crucial.},
 year = {2020}
}

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TY  - JOUR
T1  - Spectrum of Histopathological Diagnosis of Schistosomiasis as a Systemic Parasitic Infection in the North-West Nigeria
AU  - Abdullahi kabiru
AU  - Rasheed Mumini Wemimo
AU  - Mohammed Umar
AU  - Adegboye Adeyemi Taiwo
AU  - Afolayan Enoch Abiodun
AU  - Aliyu Salihu
Y1  - 2020/12/31
PY  - 2020
N1  - https://doi.org/10.11648/j.ajlm.20200506.15
DO  - 10.11648/j.ajlm.20200506.15
T2  - American Journal of Laboratory Medicine
JF  - American Journal of Laboratory Medicine
JO  - American Journal of Laboratory Medicine
SP  - 180
EP  - 184
PB  - Science Publishing Group
SN  - 2575-386X
UR  - https://doi.org/10.11648/j.ajlm.20200506.15
AB  - Introduction: Schistosomiasis is one of the neglected tropical diseases transmitted by freshwater snail in the slow-moving water of tropical rivers and ranks second among the most widespread parasitic disease in various nations in sub-Saharan Africa. Methodology: This is a 10-year retrospective study of all cases of schistosomiasis seen in the Department of Anatomic Pathology, Usmanu Danfodiyo University Teaching Sokoto between January 2008 and December 2017. All the cases of schistosomiasis diagnosed was retrieved from the surgical pathology register. The patients’ biodata and symptoms was retrieved from patients’ folder. The specimens were processed with 10% Neutral buffered formalin, stained with Haematoxylin and Eosin and reported by the pathologist at the study centre. The 2016 WHO classification of the urinary system and male genital organs were used to classify the tumours. Results: A hundred and fifty-nine patients were analysed with schistosomiasis of varying systems range from gastrointestinal, prostate, genitourinary and 38 cases of malignancies of the urinary bladder with associated schistosomiasis and prostate. In the gastrointestinal system, the appendiceal schistosomiasis accounted for 21(80.8%), rectum 3 (11.5%) and sigmoid colon 2 cases (7.7%). Benign prostatic hyperplasia with schistosomiasis accounted for 1 case (25.0%) while 3 cases (75.0%) of prostatic adenocarcinoma with schistosomiasis showed age range of 45 to 78 years. There are one hundred and eleven (111) cases of urinary bladder schistosomiasis which accounted for 86.0%, male to female ratio of 10:1 and age range from 9.0 to 78.0 years. There are 27 cases of invasive squamous cell carcinoma of the urinary bladder associated with schistosomiasis accounted for 65.8% while adenocarcinoma showed 4 cases (9.7%). Moderately differentiated SCC accounted for the largest degree of tumour differentiation associated with schistosomiasis accounted for 69.6%. Terminal haematuria is the most common symptom of urinary bladder schistosomiasis accounted for 102 cases (64.2%), followed by suprapubic abdominal pain 52 (32.5%), weight loss 30 (18.9%) for patients with malignancy Conclusion: Schistosomiasis is a public health disease in endemic regions in African countries with proper documentation on the its pathogenesis, risk factors and effective treatment and complications if left untreated. Thus, mobilization of appropriate resources to help the vulnerable in order to reduce morbidity and mortalities is very crucial.
VL  - 5
IS  - 6
ER  -

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Author Information

Abdullahi kabiru

Departments of Histopathology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria
Rasheed Mumini Wemimo

Department of Histopathology, Federal Medical Centre, Birnin-Kudu, Jigawa State, Nigeria
Mohammed Umar

Departments of Histopathology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria
Adegboye Adeyemi Taiwo

Mojitaiwo Data Services and Data Management Executives (RC-2566098), Ilorin, Kwara state Nigeria
Afolayan Enoch Abiodun

Department of Histopathology, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria
Aliyu Salihu

Department of Morbid Anatomy and Forensic Medicine, Usmanu Danfodiyo University, Sokoto, Nigeria

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Abdullahi kabiru, Rasheed Mumini Wemimo, Mohammed Umar, Adegboye Adeyemi Taiwo, Afolayan Enoch Abiodun, et al. (2020). Spectrum of Histopathological Diagnosis of Schistosomiasis as a Systemic Parasitic Infection in the North-West Nigeria. American Journal of Laboratory Medicine, 5(6), 180-184. https://doi.org/10.11648/j.ajlm.20200506.15

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ACS Style

Abdullahi kabiru; Rasheed Mumini Wemimo; Mohammed Umar; Adegboye Adeyemi Taiwo; Afolayan Enoch Abiodun, et al. Spectrum of Histopathological Diagnosis of Schistosomiasis as a Systemic Parasitic Infection in the North-West Nigeria. Am. J. Lab. Med. 2020, 5(6), 180-184. doi: 10.11648/j.ajlm.20200506.15

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AMA Style

Abdullahi kabiru, Rasheed Mumini Wemimo, Mohammed Umar, Adegboye Adeyemi Taiwo, Afolayan Enoch Abiodun, et al. Spectrum of Histopathological Diagnosis of Schistosomiasis as a Systemic Parasitic Infection in the North-West Nigeria. Am J Lab Med. 2020;5(6):180-184. doi: 10.11648/j.ajlm.20200506.15

Copy | Download

@article{10.11648/j.ajlm.20200506.15,
  author = {Abdullahi kabiru and Rasheed Mumini Wemimo and Mohammed Umar and Adegboye Adeyemi Taiwo and Afolayan Enoch Abiodun and Aliyu Salihu},
  title = {Spectrum of Histopathological Diagnosis of Schistosomiasis as a Systemic Parasitic Infection in the North-West Nigeria},
  journal = {American Journal of Laboratory Medicine},
  volume = {5},
  number = {6},
  pages = {180-184},
  doi = {10.11648/j.ajlm.20200506.15},
  url = {https://doi.org/10.11648/j.ajlm.20200506.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20200506.15},
  abstract = {Introduction: Schistosomiasis is one of the neglected tropical diseases transmitted by freshwater snail in the slow-moving water of tropical rivers and ranks second among the most widespread parasitic disease in various nations in sub-Saharan Africa. Methodology: This is a 10-year retrospective study of all cases of schistosomiasis seen in the Department of Anatomic Pathology, Usmanu Danfodiyo University Teaching Sokoto between January 2008 and December 2017. All the cases of schistosomiasis diagnosed was retrieved from the surgical pathology register. The patients’ biodata and symptoms was retrieved from patients’ folder. The specimens were processed with 10% Neutral buffered formalin, stained with Haematoxylin and Eosin and reported by the pathologist at the study centre. The 2016 WHO classification of the urinary system and male genital organs were used to classify the tumours. Results: A hundred and fifty-nine patients were analysed with schistosomiasis of varying systems range from gastrointestinal, prostate, genitourinary and 38 cases of malignancies of the urinary bladder with associated schistosomiasis and prostate. In the gastrointestinal system, the appendiceal schistosomiasis accounted for 21(80.8%), rectum 3 (11.5%) and sigmoid colon 2 cases (7.7%). Benign prostatic hyperplasia with schistosomiasis accounted for 1 case (25.0%) while 3 cases (75.0%) of prostatic adenocarcinoma with schistosomiasis showed age range of 45 to 78 years. There are one hundred and eleven (111) cases of urinary bladder schistosomiasis which accounted for 86.0%, male to female ratio of 10:1 and age range from 9.0 to 78.0 years. There are 27 cases of invasive squamous cell carcinoma of the urinary bladder associated with schistosomiasis accounted for 65.8% while adenocarcinoma showed 4 cases (9.7%). Moderately differentiated SCC accounted for the largest degree of tumour differentiation associated with schistosomiasis accounted for 69.6%. Terminal haematuria is the most common symptom of urinary bladder schistosomiasis accounted for 102 cases (64.2%), followed by suprapubic abdominal pain 52 (32.5%), weight loss 30 (18.9%) for patients with malignancy Conclusion: Schistosomiasis is a public health disease in endemic regions in African countries with proper documentation on the its pathogenesis, risk factors and effective treatment and complications if left untreated. Thus, mobilization of appropriate resources to help the vulnerable in order to reduce morbidity and mortalities is very crucial.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Spectrum of Histopathological Diagnosis of Schistosomiasis as a Systemic Parasitic Infection in the North-West Nigeria
AU  - Abdullahi kabiru
AU  - Rasheed Mumini Wemimo
AU  - Mohammed Umar
AU  - Adegboye Adeyemi Taiwo
AU  - Afolayan Enoch Abiodun
AU  - Aliyu Salihu
Y1  - 2020/12/31
PY  - 2020
N1  - https://doi.org/10.11648/j.ajlm.20200506.15
DO  - 10.11648/j.ajlm.20200506.15
T2  - American Journal of Laboratory Medicine
JF  - American Journal of Laboratory Medicine
JO  - American Journal of Laboratory Medicine
SP  - 180
EP  - 184
PB  - Science Publishing Group
SN  - 2575-386X
UR  - https://doi.org/10.11648/j.ajlm.20200506.15
AB  - Introduction: Schistosomiasis is one of the neglected tropical diseases transmitted by freshwater snail in the slow-moving water of tropical rivers and ranks second among the most widespread parasitic disease in various nations in sub-Saharan Africa. Methodology: This is a 10-year retrospective study of all cases of schistosomiasis seen in the Department of Anatomic Pathology, Usmanu Danfodiyo University Teaching Sokoto between January 2008 and December 2017. All the cases of schistosomiasis diagnosed was retrieved from the surgical pathology register. The patients’ biodata and symptoms was retrieved from patients’ folder. The specimens were processed with 10% Neutral buffered formalin, stained with Haematoxylin and Eosin and reported by the pathologist at the study centre. The 2016 WHO classification of the urinary system and male genital organs were used to classify the tumours. Results: A hundred and fifty-nine patients were analysed with schistosomiasis of varying systems range from gastrointestinal, prostate, genitourinary and 38 cases of malignancies of the urinary bladder with associated schistosomiasis and prostate. In the gastrointestinal system, the appendiceal schistosomiasis accounted for 21(80.8%), rectum 3 (11.5%) and sigmoid colon 2 cases (7.7%). Benign prostatic hyperplasia with schistosomiasis accounted for 1 case (25.0%) while 3 cases (75.0%) of prostatic adenocarcinoma with schistosomiasis showed age range of 45 to 78 years. There are one hundred and eleven (111) cases of urinary bladder schistosomiasis which accounted for 86.0%, male to female ratio of 10:1 and age range from 9.0 to 78.0 years. There are 27 cases of invasive squamous cell carcinoma of the urinary bladder associated with schistosomiasis accounted for 65.8% while adenocarcinoma showed 4 cases (9.7%). Moderately differentiated SCC accounted for the largest degree of tumour differentiation associated with schistosomiasis accounted for 69.6%. Terminal haematuria is the most common symptom of urinary bladder schistosomiasis accounted for 102 cases (64.2%), followed by suprapubic abdominal pain 52 (32.5%), weight loss 30 (18.9%) for patients with malignancy Conclusion: Schistosomiasis is a public health disease in endemic regions in African countries with proper documentation on the its pathogenesis, risk factors and effective treatment and complications if left untreated. Thus, mobilization of appropriate resources to help the vulnerable in order to reduce morbidity and mortalities is very crucial.
VL  - 5
IS  - 6
ER  -

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