Seroprevalence of Cytomegalovirus Among Paediatric Patients with Hearing Loss Attending National Ear Care Centre Kaduna Northwest Nigeria

Edward Isaac Usman; Elayo Salihu; Ogboi Johnbull Sunny; Musa Abdullahi Maikano; Edward Deborah Shetu; Shallangwa Bata Ishaku; Meshubi Florence; Isaac Agyigra

doi:doi:10.11648/j.ajlm.20170205.12

Seroprevalence of Cytomegalovirus Among Paediatric Patients with Hearing Loss Attending National Ear Care Centre Kaduna Northwest Nigeria

Edward Isaac Usman, Elayo Salihu, Ogboi Johnbull Sunny, Musa Abdullahi Maikano, Edward Deborah Shetu, Shallangwa Bata Ishaku, Meshubi Florence, Isaac Agyigra

Published in American Journal of Laboratory Medicine (Volume 2, Issue 5)

Received: 11 February 2017 Accepted: 7 March 2017 Published: 24 October 2017

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Abstract

Cytomegalovirus cause viral congenital infection at any stage of pregnancy leading to congenital defects, which can either be primary or recurrent and hearing loss is one of the common congenital CMV infection occurring in 10-15% of infected children. This study, therefore examined the seroprevalence of cytomegalovirus among paediatric patients with hearing loss attending National Ear Care Centre Kaduna northwest Nigeria. A total of 77 samples was collected from patients aged between 0-13 years, diagnosed of hearing impairment and screened for Cytomegalovirus IgG and IgM specific antibodies using ELISA method at National Ear Care Centre Kaduna State North West Nigeria. Among the 77 (100%) patients screened, 35 (45.5%) were male, while 42 (54.5%) were female with mean age (2.04). The study reveavled that, of the total numbers screened, 62 (80.5%) were IgG specific antibodies positive, while 15 (19.5%) were IgG specific antibodies negative, and none of the patient were positive for IgM specific antibodies. the result of patients based on their gender status show male patients 21 (60%) were positive while 14 (40%) were negative for CMV IgG specific antibodies. The female is 33 (78.5%) positive and 9 (21.4%) negative for CMV IgG specific antibodies. The findings hearing impairment is associated with cytomegalosvirus showing statistically significant in IgG specific antibodies (P<0.05), while in IgM it is not statistically significant. Therefore CMV infection is prevalent among patients with Hearing impairment and affect the social economic and political status of the patients.

Published in	American Journal of Laboratory Medicine (Volume 2, Issue 5)
DOI	10.11648/j.ajlm.20170205.12
Page(s)	90-95
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Cytomegalovirus (CMV), Hearing Loss, IgG, IgM, Congenital, Antibody

References

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APA Style

Edward Isaac Usman, Elayo Salihu, Ogboi Johnbull Sunny, Musa Abdullahi Maikano, Edward Deborah Shetu, et al. (2017). Seroprevalence of Cytomegalovirus Among Paediatric Patients with Hearing Loss Attending National Ear Care Centre Kaduna Northwest Nigeria. American Journal of Laboratory Medicine, 2(5), 90-95. https://doi.org/10.11648/j.ajlm.20170205.12

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ACS Style

Edward Isaac Usman; Elayo Salihu; Ogboi Johnbull Sunny; Musa Abdullahi Maikano; Edward Deborah Shetu, et al. Seroprevalence of Cytomegalovirus Among Paediatric Patients with Hearing Loss Attending National Ear Care Centre Kaduna Northwest Nigeria. Am. J. Lab. Med. 2017, 2(5), 90-95. doi: 10.11648/j.ajlm.20170205.12

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AMA Style

Edward Isaac Usman, Elayo Salihu, Ogboi Johnbull Sunny, Musa Abdullahi Maikano, Edward Deborah Shetu, et al. Seroprevalence of Cytomegalovirus Among Paediatric Patients with Hearing Loss Attending National Ear Care Centre Kaduna Northwest Nigeria. Am J Lab Med. 2017;2(5):90-95. doi: 10.11648/j.ajlm.20170205.12

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@article{10.11648/j.ajlm.20170205.12,
  author = {Edward Isaac Usman and Elayo Salihu and Ogboi Johnbull Sunny and Musa Abdullahi Maikano and Edward Deborah Shetu and Shallangwa Bata Ishaku and Meshubi Florence and Isaac Agyigra},
  title = {Seroprevalence of Cytomegalovirus Among Paediatric Patients with Hearing Loss Attending National Ear Care Centre Kaduna Northwest Nigeria},
  journal = {American Journal of Laboratory Medicine},
  volume = {2},
  number = {5},
  pages = {90-95},
  doi = {10.11648/j.ajlm.20170205.12},
  url = {https://doi.org/10.11648/j.ajlm.20170205.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20170205.12},
  abstract = {Cytomegalovirus cause viral congenital infection at any stage of pregnancy leading to congenital defects, which can either be primary or recurrent and hearing loss is one of the common congenital CMV infection occurring in 10-15% of infected children. This study, therefore examined the seroprevalence of cytomegalovirus among paediatric patients with hearing loss attending National Ear Care Centre Kaduna northwest Nigeria. A total of 77 samples was collected from patients aged between 0-13 years, diagnosed of hearing impairment and screened for Cytomegalovirus IgG and IgM specific antibodies using ELISA method at National Ear Care Centre Kaduna State North West Nigeria. Among the 77 (100%) patients screened, 35 (45.5%) were male, while 42 (54.5%) were female with mean age (2.04). The study reveavled that, of the total numbers screened, 62 (80.5%) were IgG specific antibodies positive, while 15 (19.5%) were IgG specific antibodies negative, and none of the patient were positive for IgM specific antibodies. the result of patients based on their gender status show male patients 21 (60%) were positive while 14 (40%) were negative for CMV IgG specific antibodies. The female is 33 (78.5%) positive and 9 (21.4%) negative for CMV IgG specific antibodies. The findings hearing impairment is associated with cytomegalosvirus showing statistically significant in IgG specific antibodies (P<0.05), while in IgM it is not statistically significant. Therefore CMV infection is prevalent among patients with Hearing impairment and affect the social economic and political status of the patients.},
 year = {2017}
}

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TY  - JOUR
T1  - Seroprevalence of Cytomegalovirus Among Paediatric Patients with Hearing Loss Attending National Ear Care Centre Kaduna Northwest Nigeria
AU  - Edward Isaac Usman
AU  - Elayo Salihu
AU  - Ogboi Johnbull Sunny
AU  - Musa Abdullahi Maikano
AU  - Edward Deborah Shetu
AU  - Shallangwa Bata Ishaku
AU  - Meshubi Florence
AU  - Isaac Agyigra
Y1  - 2017/10/24
PY  - 2017
N1  - https://doi.org/10.11648/j.ajlm.20170205.12
DO  - 10.11648/j.ajlm.20170205.12
T2  - American Journal of Laboratory Medicine
JF  - American Journal of Laboratory Medicine
JO  - American Journal of Laboratory Medicine
SP  - 90
EP  - 95
PB  - Science Publishing Group
SN  - 2575-386X
UR  - https://doi.org/10.11648/j.ajlm.20170205.12
AB  - Cytomegalovirus cause viral congenital infection at any stage of pregnancy leading to congenital defects, which can either be primary or recurrent and hearing loss is one of the common congenital CMV infection occurring in 10-15% of infected children. This study, therefore examined the seroprevalence of cytomegalovirus among paediatric patients with hearing loss attending National Ear Care Centre Kaduna northwest Nigeria. A total of 77 samples was collected from patients aged between 0-13 years, diagnosed of hearing impairment and screened for Cytomegalovirus IgG and IgM specific antibodies using ELISA method at National Ear Care Centre Kaduna State North West Nigeria. Among the 77 (100%) patients screened, 35 (45.5%) were male, while 42 (54.5%) were female with mean age (2.04). The study reveavled that, of the total numbers screened, 62 (80.5%) were IgG specific antibodies positive, while 15 (19.5%) were IgG specific antibodies negative, and none of the patient were positive for IgM specific antibodies. the result of patients based on their gender status show male patients 21 (60%) were positive while 14 (40%) were negative for CMV IgG specific antibodies. The female is 33 (78.5%) positive and 9 (21.4%) negative for CMV IgG specific antibodies. The findings hearing impairment is associated with cytomegalosvirus showing statistically significant in IgG specific antibodies (P<0.05), while in IgM it is not statistically significant. Therefore CMV infection is prevalent among patients with Hearing impairment and affect the social economic and political status of the patients.
VL  - 2
IS  - 5
ER  -

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Author Information

Edward Isaac Usman

Department of Medical Laboratory, Medical Microbiology Laboratory, Federal Neuropsychiatric Hospital, Barnawa, Nigeria
Elayo Salihu

Department of Virology, Federal College of Veterinary and Medical Laboratory Technology, Vom, Plateau State, Nigeria
Ogboi Johnbull Sunny

Research Department Jedima International Health Consult Ltd, Lagos, Nigeria
Musa Abdullahi Maikano

Department of Medical Laboratory, Medical Microbiology Laboratory, Federal Neuropsychiatric Hospital, Barnawa, Nigeria
Edward Deborah Shetu

Department of Virology, Tehilah Medical Laboratory, Sabon Tasha, Kaduna State, Nigeria
Shallangwa Bata Ishaku

Department of Animal Health, Federal College of Animal Health and Production Technology, Vom, Plateau State, Nigeria
Meshubi Florence

Department of Medical Laboratory, Medical Microbiology Laboratory, Federal Neuropsychiatric Hospital, Barnawa, Nigeria
Isaac Agyigra

Department of Medical Laboratory, Microbiology Unit, National Ear Care Cente, Kaduna State, Nigeria

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Edward Isaac Usman, Elayo Salihu, Ogboi Johnbull Sunny, Musa Abdullahi Maikano, Edward Deborah Shetu, et al. (2017). Seroprevalence of Cytomegalovirus Among Paediatric Patients with Hearing Loss Attending National Ear Care Centre Kaduna Northwest Nigeria. American Journal of Laboratory Medicine, 2(5), 90-95. https://doi.org/10.11648/j.ajlm.20170205.12

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ACS Style

Edward Isaac Usman; Elayo Salihu; Ogboi Johnbull Sunny; Musa Abdullahi Maikano; Edward Deborah Shetu, et al. Seroprevalence of Cytomegalovirus Among Paediatric Patients with Hearing Loss Attending National Ear Care Centre Kaduna Northwest Nigeria. Am. J. Lab. Med. 2017, 2(5), 90-95. doi: 10.11648/j.ajlm.20170205.12

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AMA Style

Edward Isaac Usman, Elayo Salihu, Ogboi Johnbull Sunny, Musa Abdullahi Maikano, Edward Deborah Shetu, et al. Seroprevalence of Cytomegalovirus Among Paediatric Patients with Hearing Loss Attending National Ear Care Centre Kaduna Northwest Nigeria. Am J Lab Med. 2017;2(5):90-95. doi: 10.11648/j.ajlm.20170205.12

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@article{10.11648/j.ajlm.20170205.12,
  author = {Edward Isaac Usman and Elayo Salihu and Ogboi Johnbull Sunny and Musa Abdullahi Maikano and Edward Deborah Shetu and Shallangwa Bata Ishaku and Meshubi Florence and Isaac Agyigra},
  title = {Seroprevalence of Cytomegalovirus Among Paediatric Patients with Hearing Loss Attending National Ear Care Centre Kaduna Northwest Nigeria},
  journal = {American Journal of Laboratory Medicine},
  volume = {2},
  number = {5},
  pages = {90-95},
  doi = {10.11648/j.ajlm.20170205.12},
  url = {https://doi.org/10.11648/j.ajlm.20170205.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20170205.12},
  abstract = {Cytomegalovirus cause viral congenital infection at any stage of pregnancy leading to congenital defects, which can either be primary or recurrent and hearing loss is one of the common congenital CMV infection occurring in 10-15% of infected children. This study, therefore examined the seroprevalence of cytomegalovirus among paediatric patients with hearing loss attending National Ear Care Centre Kaduna northwest Nigeria. A total of 77 samples was collected from patients aged between 0-13 years, diagnosed of hearing impairment and screened for Cytomegalovirus IgG and IgM specific antibodies using ELISA method at National Ear Care Centre Kaduna State North West Nigeria. Among the 77 (100%) patients screened, 35 (45.5%) were male, while 42 (54.5%) were female with mean age (2.04). The study reveavled that, of the total numbers screened, 62 (80.5%) were IgG specific antibodies positive, while 15 (19.5%) were IgG specific antibodies negative, and none of the patient were positive for IgM specific antibodies. the result of patients based on their gender status show male patients 21 (60%) were positive while 14 (40%) were negative for CMV IgG specific antibodies. The female is 33 (78.5%) positive and 9 (21.4%) negative for CMV IgG specific antibodies. The findings hearing impairment is associated with cytomegalosvirus showing statistically significant in IgG specific antibodies (P<0.05), while in IgM it is not statistically significant. Therefore CMV infection is prevalent among patients with Hearing impairment and affect the social economic and political status of the patients.},
 year = {2017}
}

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TY  - JOUR
T1  - Seroprevalence of Cytomegalovirus Among Paediatric Patients with Hearing Loss Attending National Ear Care Centre Kaduna Northwest Nigeria
AU  - Edward Isaac Usman
AU  - Elayo Salihu
AU  - Ogboi Johnbull Sunny
AU  - Musa Abdullahi Maikano
AU  - Edward Deborah Shetu
AU  - Shallangwa Bata Ishaku
AU  - Meshubi Florence
AU  - Isaac Agyigra
Y1  - 2017/10/24
PY  - 2017
N1  - https://doi.org/10.11648/j.ajlm.20170205.12
DO  - 10.11648/j.ajlm.20170205.12
T2  - American Journal of Laboratory Medicine
JF  - American Journal of Laboratory Medicine
JO  - American Journal of Laboratory Medicine
SP  - 90
EP  - 95
PB  - Science Publishing Group
SN  - 2575-386X
UR  - https://doi.org/10.11648/j.ajlm.20170205.12
AB  - Cytomegalovirus cause viral congenital infection at any stage of pregnancy leading to congenital defects, which can either be primary or recurrent and hearing loss is one of the common congenital CMV infection occurring in 10-15% of infected children. This study, therefore examined the seroprevalence of cytomegalovirus among paediatric patients with hearing loss attending National Ear Care Centre Kaduna northwest Nigeria. A total of 77 samples was collected from patients aged between 0-13 years, diagnosed of hearing impairment and screened for Cytomegalovirus IgG and IgM specific antibodies using ELISA method at National Ear Care Centre Kaduna State North West Nigeria. Among the 77 (100%) patients screened, 35 (45.5%) were male, while 42 (54.5%) were female with mean age (2.04). The study reveavled that, of the total numbers screened, 62 (80.5%) were IgG specific antibodies positive, while 15 (19.5%) were IgG specific antibodies negative, and none of the patient were positive for IgM specific antibodies. the result of patients based on their gender status show male patients 21 (60%) were positive while 14 (40%) were negative for CMV IgG specific antibodies. The female is 33 (78.5%) positive and 9 (21.4%) negative for CMV IgG specific antibodies. The findings hearing impairment is associated with cytomegalosvirus showing statistically significant in IgG specific antibodies (P<0.05), while in IgM it is not statistically significant. Therefore CMV infection is prevalent among patients with Hearing impairment and affect the social economic and political status of the patients.
VL  - 2
IS  - 5
ER  -

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