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Seroprevalence of Hepatitis B Virus in N'Djamena, Chad

Received: 30 May 2022     Accepted: 24 June 2022     Published: 30 June 2022
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Abstract

Introduction: Chronic hepatitis B virus infection is very common in sub-Saharan Africa and widely distributed worldwide. The purpose of this study was to determine the prevalence of hepatitis B virus in N'Djamena, Chad. Methodology: This was a cross-sectional study conducted in the city of N'Djamena. Three neighborhoods were randomly selected. The methodology applied was a two-stage probability survey with the neighborhoods as the primary unit and the squares (sectors) as the secondary unit. Persons from the selected households were screened for HBV infection. Results: Two hundred and ninety-nine (299) individuals were recruited in this study series. The majority were men (69.6%). The mean age was 29.5 ± 9 years with extremes of 15 to 45 years. The prevalence of those screened was 24.1% with a male predominance (54.1%). There was a statistically significant difference between HBsAg carriage and sex (p = 0.001). On the other hand, the difference between HBV carriage and education level was not statistically significant. In addition, few people had information on the modes of transmission of HBV and their serological status. Conclusion: Viral hepatitis B is a major global public health problem. However, most of the people recruited in this series were unaware of their status and very few had information on this disease.

Published in American Journal of Internal Medicine (Volume 10, Issue 3)
DOI 10.11648/j.ajim.20221003.16
Page(s) 71-74
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Prevalence, Viral Hepatitis B, HBsAg, N'Djamena, Chad

References
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[2] Gueye MN, Sarr B, Diallo et al. Evaluation de l’état des connaissances sur l’hépatite virale b des patients en consultation d’Hepato-Gastroenterologie à l’Hôpital General Idrissa Pouye (Dakar, Sénégal). [Evaluation of the state of knowledge on viral hepatitis b of patients in consultation of Hepato-Gastroenterology at the General Hospital Idrissa Pouye (Dakar, Senegal)]. OSR Journal of Dental and Medical Sciences. 2020 juin, 19: 53-57.
[3] Van Damme P, Vellinga A. Epidemiology of hepatitis B and C in Europe. Acta Gastroenterol Belg. 1998, 61 (2): 175-82.
[4] OMS. Note de synthèse: position de l'OMS.[Briefing note: WHO position.] BEH 2004; 79 (28): 253-74.
[5] Bessimbaye N, Moussa AM, Mbanga D et al. Séroprévalence de l’AgHBs et de l’anticorps AntiVHC chez les personnes infectées par le VIH1 à N’Djamena, Tchad. Bull. Soc. Pathol. [Seroprevalence of HBsAg and anti-HCV antibody in HIV-infected individuals 1 in N'Djamena, Chad Bull. Soc. Pathol] Exot. 2014; 107: 327-31.
[6] Huda K, Abdelsalam E, Shekteryea A, et al. Demographic factors influencing hepatitis B and C infection in Benghazi, Libya. Eastern Mediterranean healt journal. 2007; 13: 1-13.
[7] Barin F, Perrin J, Chotard J et al. Cross sectional and longitudinal epidemiology of hepatitis B in Senegal. Prog Med Virol. 1981; 27: 148-62.
[8] Assi C, Allah-Kouadio E, Ouattara A, et al. Couverture vaccinale contre l'hépatite virale B et prévalence de l'antigène HBs dans une profession à risque: étude transversale portant sur 244 sapeurs-pompiers de la ville d'Abidjan. [Vaccination coverage against viral hepatitis B and prevalence of HBs antigen in a high-risk profession: a cross-sectional study of 244 firemen in the city of Abidjan]. JAfr Hepatol Gastroenterol. 2011; 5: 115-8.
[9] Sombie R, Bougouma A, Diallo O, Bonkoungou G, Cisse R et al. Hépatite B chronique: aspects épidémiologique, diagnostique, thérapeutique et évolutif au centre hospitalier universitaire Yalgado Ouedraogo de Ouagadougou. [Chronic hepatitis B: epidemiological, diagnostic, therapeutic and evolutionary aspects at the Yalgado Ouedraogo University Hospital of Ouagadougou]. JAfr HepatolGastroenterol. 2010; 4: 3-10.
[10] INSEED. Enquête Démographique et de sante et à indicateurs Multiples au Tchad. [Multiple Indicator Cluster Demographic and Health Survey in Chad]. (EDS-MICS) 2014-2015. 2016.
[11] Mawouma ARN, Djoulatou AH, Komnang EO, Kimessoukie EO. Facteurs associes à l’infection de l’hépatite B chez les femmes enceintes dans les formations sanitaires du district de sante de Mokolo/Region de l’Extrême-Nord Cameroun. [Factors associated with hepatitis B infection among pregnant women in the health facilities of the Mokolo District/Far North Region of Cameroon]. PAMJ – 41 (61). 21 Jan 2022.
[12] Katile D, Konate I, Goita D. Prévalence de l’Antigène Hbs et Profil Sérologique du Virus de l’Hépatite B en Consultation de Médecine Générale à l’Hôpital Régional de Kayes au Mali. [Prevalence of Hbs Antigen and Serological Profile of Hepatitis B Virus in General Medicine Consultation at the Regional Hospital of Kayes in Mali]. Health Sci. Dis: Vol 19 (4) 2018.
[13] Ousmane A, Maiga DA, Laouali HAM. Facteurs de Risque et Prévalence de l’Antigène HBs chez les Femmes Enceintes et leurs Nouveau-Nés à Niamey au Niger. [Risk Factors and Prevalence of HBsAg in Pregnant Women and their Newborns in Niamey, Niger.]. Health Sci. Dis: Vol 19 (3) Suppl 1 Aug 2018.
[14] Khadidjatou SA, Rachidi SI, Honorat S, et al. Séroprévalence et facteurs associes à l’hépatite virale B chez les gestantes à Parakou en Republique du Benin. [Seroprevalence and factors associated with viral hepatitis B in pregnant women in Parakou, Republic of Benin]. Pan Afr Med J. 2019; 33: 226.
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Cite This Article
  • APA Style

    Mayanna Habkreo, Hassan Adam Annour, Gouaye Yahvourne Daiba, Maire Dehainssala, Adama Ngare, et al. (2022). Seroprevalence of Hepatitis B Virus in N'Djamena, Chad. American Journal of Internal Medicine, 10(3), 71-74. https://doi.org/10.11648/j.ajim.20221003.16

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    ACS Style

    Mayanna Habkreo; Hassan Adam Annour; Gouaye Yahvourne Daiba; Maire Dehainssala; Adama Ngare, et al. Seroprevalence of Hepatitis B Virus in N'Djamena, Chad. Am. J. Intern. Med. 2022, 10(3), 71-74. doi: 10.11648/j.ajim.20221003.16

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    AMA Style

    Mayanna Habkreo, Hassan Adam Annour, Gouaye Yahvourne Daiba, Maire Dehainssala, Adama Ngare, et al. Seroprevalence of Hepatitis B Virus in N'Djamena, Chad. Am J Intern Med. 2022;10(3):71-74. doi: 10.11648/j.ajim.20221003.16

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  • @article{10.11648/j.ajim.20221003.16,
      author = {Mayanna Habkreo and Hassan Adam Annour and Gouaye Yahvourne Daiba and Maire Dehainssala and Adama Ngare and Moussa Elefi and Tahir Mahamat Saleh and Ali Mahamat Moussa and Ibrahim Hamat},
      title = {Seroprevalence of Hepatitis B Virus in N'Djamena, Chad},
      journal = {American Journal of Internal Medicine},
      volume = {10},
      number = {3},
      pages = {71-74},
      doi = {10.11648/j.ajim.20221003.16},
      url = {https://doi.org/10.11648/j.ajim.20221003.16},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20221003.16},
      abstract = {Introduction: Chronic hepatitis B virus infection is very common in sub-Saharan Africa and widely distributed worldwide. The purpose of this study was to determine the prevalence of hepatitis B virus in N'Djamena, Chad. Methodology: This was a cross-sectional study conducted in the city of N'Djamena. Three neighborhoods were randomly selected. The methodology applied was a two-stage probability survey with the neighborhoods as the primary unit and the squares (sectors) as the secondary unit. Persons from the selected households were screened for HBV infection. Results: Two hundred and ninety-nine (299) individuals were recruited in this study series. The majority were men (69.6%). The mean age was 29.5 ± 9 years with extremes of 15 to 45 years. The prevalence of those screened was 24.1% with a male predominance (54.1%). There was a statistically significant difference between HBsAg carriage and sex (p = 0.001). On the other hand, the difference between HBV carriage and education level was not statistically significant. In addition, few people had information on the modes of transmission of HBV and their serological status. Conclusion: Viral hepatitis B is a major global public health problem. However, most of the people recruited in this series were unaware of their status and very few had information on this disease.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Seroprevalence of Hepatitis B Virus in N'Djamena, Chad
    AU  - Mayanna Habkreo
    AU  - Hassan Adam Annour
    AU  - Gouaye Yahvourne Daiba
    AU  - Maire Dehainssala
    AU  - Adama Ngare
    AU  - Moussa Elefi
    AU  - Tahir Mahamat Saleh
    AU  - Ali Mahamat Moussa
    AU  - Ibrahim Hamat
    Y1  - 2022/06/30
    PY  - 2022
    N1  - https://doi.org/10.11648/j.ajim.20221003.16
    DO  - 10.11648/j.ajim.20221003.16
    T2  - American Journal of Internal Medicine
    JF  - American Journal of Internal Medicine
    JO  - American Journal of Internal Medicine
    SP  - 71
    EP  - 74
    PB  - Science Publishing Group
    SN  - 2330-4324
    UR  - https://doi.org/10.11648/j.ajim.20221003.16
    AB  - Introduction: Chronic hepatitis B virus infection is very common in sub-Saharan Africa and widely distributed worldwide. The purpose of this study was to determine the prevalence of hepatitis B virus in N'Djamena, Chad. Methodology: This was a cross-sectional study conducted in the city of N'Djamena. Three neighborhoods were randomly selected. The methodology applied was a two-stage probability survey with the neighborhoods as the primary unit and the squares (sectors) as the secondary unit. Persons from the selected households were screened for HBV infection. Results: Two hundred and ninety-nine (299) individuals were recruited in this study series. The majority were men (69.6%). The mean age was 29.5 ± 9 years with extremes of 15 to 45 years. The prevalence of those screened was 24.1% with a male predominance (54.1%). There was a statistically significant difference between HBsAg carriage and sex (p = 0.001). On the other hand, the difference between HBV carriage and education level was not statistically significant. In addition, few people had information on the modes of transmission of HBV and their serological status. Conclusion: Viral hepatitis B is a major global public health problem. However, most of the people recruited in this series were unaware of their status and very few had information on this disease.
    VL  - 10
    IS  - 3
    ER  - 

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Author Information
  • Gastroenterology, Internal Medicine Department, National Reference Hospital of N'Djamena, N'Djamena, Chad

  • Pediatrics Department, University Hospital of the Renaissance, N'Djamena, Chad

  • Department of Public Health, Toukra District Hospital, N'Djamena, Chad

  • Gastroenterology, Internal Medicine Department, National Reference Hospital of N'Djamena, N'Djamena, Chad

  • Gastroenterology, Internal Medicine Department, National Reference Hospital of N'Djamena, N'Djamena, Chad

  • Gastroenterology, Internal Medicine Department, National Reference Hospital of N'Djamena, N'Djamena, Chad

  • Internal Medicine Department, University Hospital of the Renaissance, N'Djamena, Chad

  • Gastroenterology, Internal Medicine Department, National Reference Hospital of N'Djamena, N'Djamena, Chad

  • Gastroenterology, Internal Medicine Department, National Reference Hospital of N'Djamena, N'Djamena, Chad

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