The Effect of Furosemide on Arterial Blood Pressure, Blood Glucose Levels and Incidence of Heart Arrhythmias

Elvedin Osmanovic; Esed Omerkic; Semir Imamovic; Mirza Mukinovic; Halid Mahmutbegovic; Mersiha Cerkezovic

doi:doi:10.11648/j.ajim.20170503.12

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The Effect of Furosemide on Arterial Blood Pressure, Blood Glucose Levels and Incidence of Heart Arrhythmias

Elvedin Osmanovic, Esed Omerkic, Semir Imamovic, Mirza Mukinovic, Halid Mahmutbegovic, Mersiha Cerkezovic

Published in American Journal of Internal Medicine (Volume 5, Issue 3)

Received: 26 March 2017 Accepted: 5 April 2017 Published: 29 April 2017

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Abstract

Furosemide is a diuretic and is often used in the treatment of hypertension. This medicine is very good when it comes to lowering the blood pressure, and this is also a drug of choice when it comes to the stage of hypertensive urgencies and emergencies. It can be administered intravenously, and the effects reach a maximum within 30 minutes. Due to the fact that this medicine causes a loss of potassium ions it can also affect the reduction of insulin in the blood, and thus the increase in blood glucose and arrhythmias. A prospective random study was carried out in Emergency Medical Service of Public Health Institution Center “Zivinice’’, where we analyzed 120 patients which were suffering from hypertension heart disease, and diabetes. We included all 120 patient whom suffering from hypertension and diabetes starting February till end of July 2016. Data for analysis: age, gender, bodymass index, analysis of the arterial blood pressure value, characteristic laboratory changes, analysis of electrocardiography. Looking at all the three groups of patients, it can be noticed that the maximum value of arterial blood pressure upon arrival at the Emergency Medical service had patients suffering from hypertension and diabetes, where the average value of arterial blood pressure was 173/113 mmHg. According to analysis for all three observed groups of patients, after treatment with furosemide there is no statistical significance in the incidence of arrhythmias between the groups where. Looking at the summary for all three groups of patients, the average value increase of blood glucose after treatment with furosemide is 0.7 mmol/l. Furosemide is safe for the treatment of hypertension in diabetic patients. It does not cause an increase in blood glucose levels.

Published in	American Journal of Internal Medicine (Volume 5, Issue 3)
DOI	10.11648/j.ajim.20170503.12
Page(s)	41-45
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Furosemide, Hypertension, Diabetes, Arrhythmias

References

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[2]	H. Brown et all, “ Body mass index and the prevalence of hypertension and dyslipidemia”, [WWW] http://www.ncbi.nlm.nih.gov/pubmed/.
[3]	E Merck, “ The Merck Manual of Diagnosis and Therapy”, Merck Manuals, 2011, pp. 103-105.
[4]	P. Kumar, “ Kumar and Clark's Clinical Medicine”, Saunders ltd., 2012 vol. 11, pp.1243-1250.
[5]	JH. Bauer and WC. Gauntner, “Effect of potassium chloride on plasma renin activity and plasma aldosterone during sodium restriction in normal man”, Kidney Int., 1979, pp. 246-30.
[6]	T. Kenny, “ High blood pressure (hypertension)”, [WWW] http://www.patient.co.uk.
[7]	E. Osmanovic, “Novotkrivena, neliječena i neadakvatno tretrirana hipertenzija kao veliki javno zdravstveni problem u hitnoj pomoći”, 2013, pp. 56-67.
[8]	LS. Webber and AL Bedimo-Rung, “The obesity epidemic: incidence and prevalence”, J Lo State Med Soc., vol 11, 2005, pp.157.
[9]	L. Lind, C. Berne, T. Pollare and H. Lithell, “Metabolic effects of anti-hypertensive treatment with nifedipine or furosemide: a double-blind, cross-over study”, Journal of Human Hypertension, vol. 9(2), 1995, 137-141.
[10]	Calhoun DA et al (2008) Resistant hypertension: diagnosis, evaluation, and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Hypertension 51:1403.
[11]	Pollare T, Lithell H, Selinus I, Berne C. Sensitivity to insulin during treatment with atenolol and metoprolol: a randomised, double blind study of effects on carbohydrate and lipoprotein metabolism in hypertensive patients. Department of Geriatrics, Uppsala University, Sweden. 2014:125:456-459.
[12]	FM. Sacks et al., “ Effects on blood pressure of reduced dietary sodium and the dietary approaches to stop hypertension (DASH) diet”, NEJM, vol. 344, pp. 3-10.
[13]	O. Samuelsson,” Hypertension in middle-aged men”,. Acta Med Scand Suppl., 2000, 702:1–79.

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APA Style

Elvedin Osmanovic, Esed Omerkic, Semir Imamovic, Mirza Mukinovic, Halid Mahmutbegovic, et al. (2017). The Effect of Furosemide on Arterial Blood Pressure, Blood Glucose Levels and Incidence of Heart Arrhythmias. American Journal of Internal Medicine, 5(3), 41-45. https://doi.org/10.11648/j.ajim.20170503.12

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ACS Style

Elvedin Osmanovic; Esed Omerkic; Semir Imamovic; Mirza Mukinovic; Halid Mahmutbegovic, et al. The Effect of Furosemide on Arterial Blood Pressure, Blood Glucose Levels and Incidence of Heart Arrhythmias. Am. J. Intern. Med. 2017, 5(3), 41-45. doi: 10.11648/j.ajim.20170503.12

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AMA Style

Elvedin Osmanovic, Esed Omerkic, Semir Imamovic, Mirza Mukinovic, Halid Mahmutbegovic, et al. The Effect of Furosemide on Arterial Blood Pressure, Blood Glucose Levels and Incidence of Heart Arrhythmias. Am J Intern Med. 2017;5(3):41-45. doi: 10.11648/j.ajim.20170503.12

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@article{10.11648/j.ajim.20170503.12,
  author = {Elvedin Osmanovic and Esed Omerkic and Semir Imamovic and Mirza Mukinovic and Halid Mahmutbegovic and Mersiha Cerkezovic},
  title = {The Effect of Furosemide on Arterial Blood Pressure, Blood Glucose Levels and Incidence of Heart Arrhythmias},
  journal = {American Journal of Internal Medicine},
  volume = {5},
  number = {3},
  pages = {41-45},
  doi = {10.11648/j.ajim.20170503.12},
  url = {https://doi.org/10.11648/j.ajim.20170503.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20170503.12},
  abstract = {Furosemide is a diuretic and is often used in the treatment of hypertension. This medicine is very good when it comes to lowering the blood pressure, and this is also a drug of choice when it comes to the stage of hypertensive urgencies and emergencies. It can be administered intravenously, and the effects reach a maximum within 30 minutes. Due to the fact that this medicine causes a loss of potassium ions it can also affect the reduction of insulin in the blood, and thus the increase in blood glucose and arrhythmias. A prospective random study was carried out in Emergency Medical Service of Public Health Institution Center “Zivinice’’, where we analyzed 120 patients which were suffering from hypertension heart disease, and diabetes. We included all 120 patient whom suffering from hypertension and diabetes starting February till end of July 2016. Data for analysis: age, gender, bodymass index, analysis of the arterial blood pressure value, characteristic laboratory changes, analysis of electrocardiography. Looking at all the three groups of patients, it can be noticed that the maximum value of arterial blood pressure upon arrival at the Emergency Medical service had patients suffering from hypertension and diabetes, where the average value of arterial blood pressure was 173/113 mmHg. According to analysis for all three observed groups of patients, after treatment with furosemide there is no statistical significance in the incidence of arrhythmias between the groups where. Looking at the summary for all three groups of patients, the average value increase of blood glucose after treatment with furosemide is 0.7 mmol/l. Furosemide is safe for the treatment of hypertension in diabetic patients. It does not cause an increase in blood glucose levels.},
 year = {2017}
}

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TY  - JOUR
T1  - The Effect of Furosemide on Arterial Blood Pressure, Blood Glucose Levels and Incidence of Heart Arrhythmias
AU  - Elvedin Osmanovic
AU  - Esed Omerkic
AU  - Semir Imamovic
AU  - Mirza Mukinovic
AU  - Halid Mahmutbegovic
AU  - Mersiha Cerkezovic
Y1  - 2017/04/29
PY  - 2017
N1  - https://doi.org/10.11648/j.ajim.20170503.12
DO  - 10.11648/j.ajim.20170503.12
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 41
EP  - 45
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20170503.12
AB  - Furosemide is a diuretic and is often used in the treatment of hypertension. This medicine is very good when it comes to lowering the blood pressure, and this is also a drug of choice when it comes to the stage of hypertensive urgencies and emergencies. It can be administered intravenously, and the effects reach a maximum within 30 minutes. Due to the fact that this medicine causes a loss of potassium ions it can also affect the reduction of insulin in the blood, and thus the increase in blood glucose and arrhythmias. A prospective random study was carried out in Emergency Medical Service of Public Health Institution Center “Zivinice’’, where we analyzed 120 patients which were suffering from hypertension heart disease, and diabetes. We included all 120 patient whom suffering from hypertension and diabetes starting February till end of July 2016. Data for analysis: age, gender, bodymass index, analysis of the arterial blood pressure value, characteristic laboratory changes, analysis of electrocardiography. Looking at all the three groups of patients, it can be noticed that the maximum value of arterial blood pressure upon arrival at the Emergency Medical service had patients suffering from hypertension and diabetes, where the average value of arterial blood pressure was 173/113 mmHg. According to analysis for all three observed groups of patients, after treatment with furosemide there is no statistical significance in the incidence of arrhythmias between the groups where. Looking at the summary for all three groups of patients, the average value increase of blood glucose after treatment with furosemide is 0.7 mmol/l. Furosemide is safe for the treatment of hypertension in diabetic patients. It does not cause an increase in blood glucose levels.
VL  - 5
IS  - 3
ER  -

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Author Information

Elvedin Osmanovic

Emergency Department, Health Center Zivinice, Zivinice, Bosnia and Herzegovina
Esed Omerkic

Emergency Department, Health Center Zivinice, Zivinice, Bosnia and Herzegovina
Semir Imamovic

Department of Anesthesiology and Resuscitation, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina
Mirza Mukinovic

Emergency Department, Health Center Zivinice, Zivinice, Bosnia and Herzegovina
Halid Mahmutbegovic

Department of Quality Control, Health Center Zivinice, Zivinice, Bosnia and Herzegovina
Mersiha Cerkezovic

Department of Internal Medicine, Health Center Zivinice, Zivinice, Bosnia and Herzegovina

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APA Style

Elvedin Osmanovic, Esed Omerkic, Semir Imamovic, Mirza Mukinovic, Halid Mahmutbegovic, et al. (2017). The Effect of Furosemide on Arterial Blood Pressure, Blood Glucose Levels and Incidence of Heart Arrhythmias. American Journal of Internal Medicine, 5(3), 41-45. https://doi.org/10.11648/j.ajim.20170503.12

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ACS Style

Elvedin Osmanovic; Esed Omerkic; Semir Imamovic; Mirza Mukinovic; Halid Mahmutbegovic, et al. The Effect of Furosemide on Arterial Blood Pressure, Blood Glucose Levels and Incidence of Heart Arrhythmias. Am. J. Intern. Med. 2017, 5(3), 41-45. doi: 10.11648/j.ajim.20170503.12

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AMA Style

Elvedin Osmanovic, Esed Omerkic, Semir Imamovic, Mirza Mukinovic, Halid Mahmutbegovic, et al. The Effect of Furosemide on Arterial Blood Pressure, Blood Glucose Levels and Incidence of Heart Arrhythmias. Am J Intern Med. 2017;5(3):41-45. doi: 10.11648/j.ajim.20170503.12

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@article{10.11648/j.ajim.20170503.12,
  author = {Elvedin Osmanovic and Esed Omerkic and Semir Imamovic and Mirza Mukinovic and Halid Mahmutbegovic and Mersiha Cerkezovic},
  title = {The Effect of Furosemide on Arterial Blood Pressure, Blood Glucose Levels and Incidence of Heart Arrhythmias},
  journal = {American Journal of Internal Medicine},
  volume = {5},
  number = {3},
  pages = {41-45},
  doi = {10.11648/j.ajim.20170503.12},
  url = {https://doi.org/10.11648/j.ajim.20170503.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20170503.12},
  abstract = {Furosemide is a diuretic and is often used in the treatment of hypertension. This medicine is very good when it comes to lowering the blood pressure, and this is also a drug of choice when it comes to the stage of hypertensive urgencies and emergencies. It can be administered intravenously, and the effects reach a maximum within 30 minutes. Due to the fact that this medicine causes a loss of potassium ions it can also affect the reduction of insulin in the blood, and thus the increase in blood glucose and arrhythmias. A prospective random study was carried out in Emergency Medical Service of Public Health Institution Center “Zivinice’’, where we analyzed 120 patients which were suffering from hypertension heart disease, and diabetes. We included all 120 patient whom suffering from hypertension and diabetes starting February till end of July 2016. Data for analysis: age, gender, bodymass index, analysis of the arterial blood pressure value, characteristic laboratory changes, analysis of electrocardiography. Looking at all the three groups of patients, it can be noticed that the maximum value of arterial blood pressure upon arrival at the Emergency Medical service had patients suffering from hypertension and diabetes, where the average value of arterial blood pressure was 173/113 mmHg. According to analysis for all three observed groups of patients, after treatment with furosemide there is no statistical significance in the incidence of arrhythmias between the groups where. Looking at the summary for all three groups of patients, the average value increase of blood glucose after treatment with furosemide is 0.7 mmol/l. Furosemide is safe for the treatment of hypertension in diabetic patients. It does not cause an increase in blood glucose levels.},
 year = {2017}
}

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TY  - JOUR
T1  - The Effect of Furosemide on Arterial Blood Pressure, Blood Glucose Levels and Incidence of Heart Arrhythmias
AU  - Elvedin Osmanovic
AU  - Esed Omerkic
AU  - Semir Imamovic
AU  - Mirza Mukinovic
AU  - Halid Mahmutbegovic
AU  - Mersiha Cerkezovic
Y1  - 2017/04/29
PY  - 2017
N1  - https://doi.org/10.11648/j.ajim.20170503.12
DO  - 10.11648/j.ajim.20170503.12
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 41
EP  - 45
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20170503.12
AB  - Furosemide is a diuretic and is often used in the treatment of hypertension. This medicine is very good when it comes to lowering the blood pressure, and this is also a drug of choice when it comes to the stage of hypertensive urgencies and emergencies. It can be administered intravenously, and the effects reach a maximum within 30 minutes. Due to the fact that this medicine causes a loss of potassium ions it can also affect the reduction of insulin in the blood, and thus the increase in blood glucose and arrhythmias. A prospective random study was carried out in Emergency Medical Service of Public Health Institution Center “Zivinice’’, where we analyzed 120 patients which were suffering from hypertension heart disease, and diabetes. We included all 120 patient whom suffering from hypertension and diabetes starting February till end of July 2016. Data for analysis: age, gender, bodymass index, analysis of the arterial blood pressure value, characteristic laboratory changes, analysis of electrocardiography. Looking at all the three groups of patients, it can be noticed that the maximum value of arterial blood pressure upon arrival at the Emergency Medical service had patients suffering from hypertension and diabetes, where the average value of arterial blood pressure was 173/113 mmHg. According to analysis for all three observed groups of patients, after treatment with furosemide there is no statistical significance in the incidence of arrhythmias between the groups where. Looking at the summary for all three groups of patients, the average value increase of blood glucose after treatment with furosemide is 0.7 mmol/l. Furosemide is safe for the treatment of hypertension in diabetic patients. It does not cause an increase in blood glucose levels.
VL  - 5
IS  - 3
ER  -

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