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The Frequency and Etiology of Recurrent Apthous Stomatitis in Helicobacter Pylori Positive Patients

Received: 25 June 2014     Accepted: 25 July 2014     Published: 30 July 2014
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Abstract

Objective: Recurrent aphthous ulcerations (RAU) is a disease characterized by recurrent painful ulcerations of the oral mucosa. The etiopathogenesis of the disease still unknown, and recently the role of Helicobacter pylori (HP) is overlooked. RAU frequency and etiologic factors of HP positive patients have been investigated in this study. Materials and Methods: 64 patients who attended to Mustafa Kemal University Department of Nuclear Medicine and presented with positive HP were included in the study. A questionnaire about sociodemographic characteristics and etiologies for RAU was administered to the patients. Results: The mean age of 64 patients determined a HP infection with C- 14 urea breath test was 54.1 ± 19.3. 35(54.7% ) of 64 patients were females , 29( 45.3 % ) of 64 patients were males . Smoking prevalence rate were 65.6%. 43.8 % of patients had RAU 1-3 times per year , 35.9 % more than 3 times. 35.9 % of the patients had RAU in tongue, 28.1% of the patients had RAU on lips, tongue and cheek. 42% of the patients had minor, 51.6 % of patients had major, 6.4% of patients had herpetiform ulcers. The average degree of pain ( score out of ten ) were found 7.39 ± 1.54 . There was correlation between the number of aphthae in the past year and the degree of pain. The degree of pain in herpetiform ulcers were higher. Familial history was found to be 32.8%. 68.7 % of the patients had reflux. 51.6 % of the patients declared hoarseness. Conclusion: High incidence of RAU in HP positive patients and patients with reflux may cause the idea that HP may be suspected to be an etiologic factor of RAU.

Published in American Journal of Internal Medicine (Volume 2, Issue 4)
DOI 10.11648/j.ajim.20140204.14
Page(s) 72-78
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Helicobacter Pylori, Recurrent Aphthous Ulcers, Aphthae

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    Ayşe Neslin Akkoca, Zeynep Tuba Özdemir, Serdar Yanık, Seçil Günher Arıca, Hülya Yalçin, et al. (2014). The Frequency and Etiology of Recurrent Apthous Stomatitis in Helicobacter Pylori Positive Patients. American Journal of Internal Medicine, 2(4), 72-78. https://doi.org/10.11648/j.ajim.20140204.14

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    Ayşe Neslin Akkoca; Zeynep Tuba Özdemir; Serdar Yanık; Seçil Günher Arıca; Hülya Yalçin, et al. The Frequency and Etiology of Recurrent Apthous Stomatitis in Helicobacter Pylori Positive Patients. Am. J. Intern. Med. 2014, 2(4), 72-78. doi: 10.11648/j.ajim.20140204.14

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    Ayşe Neslin Akkoca, Zeynep Tuba Özdemir, Serdar Yanık, Seçil Günher Arıca, Hülya Yalçin, et al. The Frequency and Etiology of Recurrent Apthous Stomatitis in Helicobacter Pylori Positive Patients. Am J Intern Med. 2014;2(4):72-78. doi: 10.11648/j.ajim.20140204.14

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  • @article{10.11648/j.ajim.20140204.14,
      author = {Ayşe Neslin Akkoca and Zeynep Tuba Özdemir and Serdar Yanık and Seçil Günher Arıca and Hülya Yalçin and Gül Soylu Özler},
      title = {The Frequency and Etiology of Recurrent Apthous Stomatitis in Helicobacter Pylori Positive Patients},
      journal = {American Journal of Internal Medicine},
      volume = {2},
      number = {4},
      pages = {72-78},
      doi = {10.11648/j.ajim.20140204.14},
      url = {https://doi.org/10.11648/j.ajim.20140204.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20140204.14},
      abstract = {Objective: Recurrent aphthous ulcerations (RAU) is a disease characterized by recurrent painful ulcerations of the oral mucosa. The etiopathogenesis of the disease still unknown, and recently the role of Helicobacter pylori (HP) is overlooked. RAU frequency and etiologic factors of HP positive patients have been investigated in this study. Materials and Methods: 64 patients who attended to Mustafa Kemal University Department of Nuclear Medicine and presented with positive HP were included in the study. A questionnaire about sociodemographic characteristics and etiologies for RAU was administered to the patients. Results: The mean age of 64 patients determined a HP infection with C- 14 urea breath test was 54.1 ± 19.3. 35(54.7% ) of 64 patients were females , 29( 45.3 % ) of 64 patients were males . Smoking prevalence rate were 65.6%. 43.8 % of patients had RAU 1-3 times per year , 35.9 % more than 3 times. 35.9 % of the patients had RAU in tongue, 28.1% of the patients had RAU on lips, tongue and cheek. 42% of the patients had minor, 51.6 % of patients had major, 6.4% of patients had herpetiform ulcers. The average degree of pain ( score out of ten ) were found 7.39 ± 1.54 . There was correlation between the number of aphthae in the past year and the degree of pain. The degree of pain in herpetiform ulcers were higher. Familial history was found to be 32.8%. 68.7 % of the patients had reflux. 51.6 % of the patients declared hoarseness. Conclusion: High incidence of RAU in HP positive patients and patients with reflux may cause the idea that HP may be suspected to be an etiologic factor of RAU.},
     year = {2014}
    }
    

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  • TY  - JOUR
    T1  - The Frequency and Etiology of Recurrent Apthous Stomatitis in Helicobacter Pylori Positive Patients
    AU  - Ayşe Neslin Akkoca
    AU  - Zeynep Tuba Özdemir
    AU  - Serdar Yanık
    AU  - Seçil Günher Arıca
    AU  - Hülya Yalçin
    AU  - Gül Soylu Özler
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    PY  - 2014
    N1  - https://doi.org/10.11648/j.ajim.20140204.14
    DO  - 10.11648/j.ajim.20140204.14
    T2  - American Journal of Internal Medicine
    JF  - American Journal of Internal Medicine
    JO  - American Journal of Internal Medicine
    SP  - 72
    EP  - 78
    PB  - Science Publishing Group
    SN  - 2330-4324
    UR  - https://doi.org/10.11648/j.ajim.20140204.14
    AB  - Objective: Recurrent aphthous ulcerations (RAU) is a disease characterized by recurrent painful ulcerations of the oral mucosa. The etiopathogenesis of the disease still unknown, and recently the role of Helicobacter pylori (HP) is overlooked. RAU frequency and etiologic factors of HP positive patients have been investigated in this study. Materials and Methods: 64 patients who attended to Mustafa Kemal University Department of Nuclear Medicine and presented with positive HP were included in the study. A questionnaire about sociodemographic characteristics and etiologies for RAU was administered to the patients. Results: The mean age of 64 patients determined a HP infection with C- 14 urea breath test was 54.1 ± 19.3. 35(54.7% ) of 64 patients were females , 29( 45.3 % ) of 64 patients were males . Smoking prevalence rate were 65.6%. 43.8 % of patients had RAU 1-3 times per year , 35.9 % more than 3 times. 35.9 % of the patients had RAU in tongue, 28.1% of the patients had RAU on lips, tongue and cheek. 42% of the patients had minor, 51.6 % of patients had major, 6.4% of patients had herpetiform ulcers. The average degree of pain ( score out of ten ) were found 7.39 ± 1.54 . There was correlation between the number of aphthae in the past year and the degree of pain. The degree of pain in herpetiform ulcers were higher. Familial history was found to be 32.8%. 68.7 % of the patients had reflux. 51.6 % of the patients declared hoarseness. Conclusion: High incidence of RAU in HP positive patients and patients with reflux may cause the idea that HP may be suspected to be an etiologic factor of RAU.
    VL  - 2
    IS  - 4
    ER  - 

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