Exposure to ultraviolet B (UVB) has an impact in the form of changes in the dermis collagen fibers and can result in decreasing the thickness and density of collagen. This study aims to assess the effectiveness of mangosteen pericarp extract to the thickness and density of collagen in mice skin after being exposed to UVB. This research was conducted in the animal laboratory and the anatomic pathology laboratory Hasanuddin University, Makassar. The study used pure animal experimental research design with control group. The samples were 24 mice that were divided into four groups: normal, UVB, ethanol and mangosteen groups. Mangosteen pericarp extract with a concentration of 50% was applied shortly after the mice were exposed to UVB. The thickness and density of collagen in normal group was significantly higher than UVB and ethanol groups. Mangosteen groups showed collagen density higher than UVB and ethanol groups. No significant differences between mangosteen and normal group. No significant differences between ethanol and UVB groups. Mangosteen pericarp extract with a concentration of 50% (2 mg / gBW mice) can increase the thickness and density of collagen in mice skin exposed to UVB.
| Published in | American Journal of Clinical and Experimental Medicine (Volume 4, Issue 3) |
| DOI | 10.11648/j.ajcem.20160403.19 |
| Page(s) | 88-93 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2016. Published by Science Publishing Group |
Collagen, Mangosteen Pericarp Extract, Mice Skin, Ultraviolet-B
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APA Style
Elfa Wirdani Fitri, Anis Irawan Anwar, Khairuddin Djawad, Arifin Seweng, Husni Changara, et al. (2016). The Effectiveness of Topical Mangosteen Pericarp Extract on the Collagen of Mice Skin Exposed to Ultraviolet B. American Journal of Clinical and Experimental Medicine, 4(3), 88-93. https://doi.org/10.11648/j.ajcem.20160403.19
ACS Style
Elfa Wirdani Fitri; Anis Irawan Anwar; Khairuddin Djawad; Arifin Seweng; Husni Changara, et al. The Effectiveness of Topical Mangosteen Pericarp Extract on the Collagen of Mice Skin Exposed to Ultraviolet B. Am. J. Clin. Exp. Med. 2016, 4(3), 88-93. doi: 10.11648/j.ajcem.20160403.19
AMA Style
Elfa Wirdani Fitri, Anis Irawan Anwar, Khairuddin Djawad, Arifin Seweng, Husni Changara, et al. The Effectiveness of Topical Mangosteen Pericarp Extract on the Collagen of Mice Skin Exposed to Ultraviolet B. Am J Clin Exp Med. 2016;4(3):88-93. doi: 10.11648/j.ajcem.20160403.19
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Download@article{10.11648/j.ajcem.20160403.19,
author = {Elfa Wirdani Fitri and Anis Irawan Anwar and Khairuddin Djawad and Arifin Seweng and Husni Changara and Gemini Alam},
title = {The Effectiveness of Topical Mangosteen Pericarp Extract on the Collagen of Mice Skin Exposed to Ultraviolet B},
journal = {American Journal of Clinical and Experimental Medicine},
volume = {4},
number = {3},
pages = {88-93},
doi = {10.11648/j.ajcem.20160403.19},
url = {https://doi.org/10.11648/j.ajcem.20160403.19},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20160403.19},
abstract = {Exposure to ultraviolet B (UVB) has an impact in the form of changes in the dermis collagen fibers and can result in decreasing the thickness and density of collagen. This study aims to assess the effectiveness of mangosteen pericarp extract to the thickness and density of collagen in mice skin after being exposed to UVB. This research was conducted in the animal laboratory and the anatomic pathology laboratory Hasanuddin University, Makassar. The study used pure animal experimental research design with control group. The samples were 24 mice that were divided into four groups: normal, UVB, ethanol and mangosteen groups. Mangosteen pericarp extract with a concentration of 50% was applied shortly after the mice were exposed to UVB. The thickness and density of collagen in normal group was significantly higher than UVB and ethanol groups. Mangosteen groups showed collagen density higher than UVB and ethanol groups. No significant differences between mangosteen and normal group. No significant differences between ethanol and UVB groups. Mangosteen pericarp extract with a concentration of 50% (2 mg / gBW mice) can increase the thickness and density of collagen in mice skin exposed to UVB.},
year = {2016}
}
TY - JOUR T1 - The Effectiveness of Topical Mangosteen Pericarp Extract on the Collagen of Mice Skin Exposed to Ultraviolet B AU - Elfa Wirdani Fitri AU - Anis Irawan Anwar AU - Khairuddin Djawad AU - Arifin Seweng AU - Husni Changara AU - Gemini Alam Y1 - 2016/06/01 PY - 2016 N1 - https://doi.org/10.11648/j.ajcem.20160403.19 DO - 10.11648/j.ajcem.20160403.19 T2 - American Journal of Clinical and Experimental Medicine JF - American Journal of Clinical and Experimental Medicine JO - American Journal of Clinical and Experimental Medicine SP - 88 EP - 93 PB - Science Publishing Group SN - 2330-8133 UR - https://doi.org/10.11648/j.ajcem.20160403.19 AB - Exposure to ultraviolet B (UVB) has an impact in the form of changes in the dermis collagen fibers and can result in decreasing the thickness and density of collagen. This study aims to assess the effectiveness of mangosteen pericarp extract to the thickness and density of collagen in mice skin after being exposed to UVB. This research was conducted in the animal laboratory and the anatomic pathology laboratory Hasanuddin University, Makassar. The study used pure animal experimental research design with control group. The samples were 24 mice that were divided into four groups: normal, UVB, ethanol and mangosteen groups. Mangosteen pericarp extract with a concentration of 50% was applied shortly after the mice were exposed to UVB. The thickness and density of collagen in normal group was significantly higher than UVB and ethanol groups. Mangosteen groups showed collagen density higher than UVB and ethanol groups. No significant differences between mangosteen and normal group. No significant differences between ethanol and UVB groups. Mangosteen pericarp extract with a concentration of 50% (2 mg / gBW mice) can increase the thickness and density of collagen in mice skin exposed to UVB. VL - 4 IS - 3 ER -
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