Introduction: The incidence of myocarditis on Dengue Hemorrhagic Fever (DHF) is still controversial because the disease was asymptomatic and definitive diagnosis only with endocardial biopsy. More specific and sensitive examination to detect the cardiac disorder is cardiac enzyme likes the level of troponin T. Objective: This study aims to evaluate the level of troponin T in patients with dengue shock syndrome (DSS) and dengue hemorrhagic fever without shock. Methods: The research conducted a cross-sectional study at Child Health Department of Dr. Wahidin Sudirohusodo Hospital, Makassar, from July to October 2012. The population included children with DHF admitted to the hospital of Dr. Wahidin Sudirohusodo, Ibnu Sina and Faisal Islamic. Diagnosis of DHF was established based on history taking, physical and laboratory examination. Results: There were 70 samples who met the criteria, including 35 patients of DSS and 35 patients of dengue hemorrhagic fever without shock. The level of troponin T was higher on DSS group than DHF group with the cut off point of ≥0.007 ng/ml is the best level to distinguish between dengue shock syndrome and dengue hemorrhagic fever without shock (p=0.000, sensitivity 97.1%, specificity 88.6%, positive predictive value 89.5%, negative predictive value 96.9%,OR 18.7; 95% CI 15.3–1417.5). Conclusion: The level of troponin T was higher on DSS group than dengue hemorrhagic fever without shock group because on DSS occurs to stress caused by hypoperfusion. But the level of troponin T between two groups within normal limits, not found cardiac disorder such as myocarditis on DHF.
| Published in | American Journal of Clinical and Experimental Medicine (Volume 3, Issue 4) |
| DOI | 10.11648/j.ajcem.20150304.14 |
| Page(s) | 149-153 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2015. Published by Science Publishing Group |
Troponin T Levels, Dengue Hemorrhagic Fever, Children
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APA Style
Burhanuddin Iskandar, Juherinah, Dasril Daud, Andi Dwi Bahagia Febriani. (2015). The Levels of Troponin T in Patients with Dengue Hemorrhagic Fever. American Journal of Clinical and Experimental Medicine, 3(4), 149-153. https://doi.org/10.11648/j.ajcem.20150304.14
ACS Style
Burhanuddin Iskandar; Juherinah; Dasril Daud; Andi Dwi Bahagia Febriani. The Levels of Troponin T in Patients with Dengue Hemorrhagic Fever. Am. J. Clin. Exp. Med. 2015, 3(4), 149-153. doi: 10.11648/j.ajcem.20150304.14
AMA Style
Burhanuddin Iskandar, Juherinah, Dasril Daud, Andi Dwi Bahagia Febriani. The Levels of Troponin T in Patients with Dengue Hemorrhagic Fever. Am J Clin Exp Med. 2015;3(4):149-153. doi: 10.11648/j.ajcem.20150304.14
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Download@article{10.11648/j.ajcem.20150304.14,
author = {Burhanuddin Iskandar and Juherinah and Dasril Daud and Andi Dwi Bahagia Febriani},
title = {The Levels of Troponin T in Patients with Dengue Hemorrhagic Fever},
journal = {American Journal of Clinical and Experimental Medicine},
volume = {3},
number = {4},
pages = {149-153},
doi = {10.11648/j.ajcem.20150304.14},
url = {https://doi.org/10.11648/j.ajcem.20150304.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20150304.14},
abstract = {Introduction: The incidence of myocarditis on Dengue Hemorrhagic Fever (DHF) is still controversial because the disease was asymptomatic and definitive diagnosis only with endocardial biopsy. More specific and sensitive examination to detect the cardiac disorder is cardiac enzyme likes the level of troponin T. Objective: This study aims to evaluate the level of troponin T in patients with dengue shock syndrome (DSS) and dengue hemorrhagic fever without shock. Methods: The research conducted a cross-sectional study at Child Health Department of Dr. Wahidin Sudirohusodo Hospital, Makassar, from July to October 2012. The population included children with DHF admitted to the hospital of Dr. Wahidin Sudirohusodo, Ibnu Sina and Faisal Islamic. Diagnosis of DHF was established based on history taking, physical and laboratory examination. Results: There were 70 samples who met the criteria, including 35 patients of DSS and 35 patients of dengue hemorrhagic fever without shock. The level of troponin T was higher on DSS group than DHF group with the cut off point of ≥0.007 ng/ml is the best level to distinguish between dengue shock syndrome and dengue hemorrhagic fever without shock (p=0.000, sensitivity 97.1%, specificity 88.6%, positive predictive value 89.5%, negative predictive value 96.9%,OR 18.7; 95% CI 15.3–1417.5). Conclusion: The level of troponin T was higher on DSS group than dengue hemorrhagic fever without shock group because on DSS occurs to stress caused by hypoperfusion. But the level of troponin T between two groups within normal limits, not found cardiac disorder such as myocarditis on DHF.},
year = {2015}
}
TY - JOUR T1 - The Levels of Troponin T in Patients with Dengue Hemorrhagic Fever AU - Burhanuddin Iskandar AU - Juherinah AU - Dasril Daud AU - Andi Dwi Bahagia Febriani Y1 - 2015/06/19 PY - 2015 N1 - https://doi.org/10.11648/j.ajcem.20150304.14 DO - 10.11648/j.ajcem.20150304.14 T2 - American Journal of Clinical and Experimental Medicine JF - American Journal of Clinical and Experimental Medicine JO - American Journal of Clinical and Experimental Medicine SP - 149 EP - 153 PB - Science Publishing Group SN - 2330-8133 UR - https://doi.org/10.11648/j.ajcem.20150304.14 AB - Introduction: The incidence of myocarditis on Dengue Hemorrhagic Fever (DHF) is still controversial because the disease was asymptomatic and definitive diagnosis only with endocardial biopsy. More specific and sensitive examination to detect the cardiac disorder is cardiac enzyme likes the level of troponin T. Objective: This study aims to evaluate the level of troponin T in patients with dengue shock syndrome (DSS) and dengue hemorrhagic fever without shock. Methods: The research conducted a cross-sectional study at Child Health Department of Dr. Wahidin Sudirohusodo Hospital, Makassar, from July to October 2012. The population included children with DHF admitted to the hospital of Dr. Wahidin Sudirohusodo, Ibnu Sina and Faisal Islamic. Diagnosis of DHF was established based on history taking, physical and laboratory examination. Results: There were 70 samples who met the criteria, including 35 patients of DSS and 35 patients of dengue hemorrhagic fever without shock. The level of troponin T was higher on DSS group than DHF group with the cut off point of ≥0.007 ng/ml is the best level to distinguish between dengue shock syndrome and dengue hemorrhagic fever without shock (p=0.000, sensitivity 97.1%, specificity 88.6%, positive predictive value 89.5%, negative predictive value 96.9%,OR 18.7; 95% CI 15.3–1417.5). Conclusion: The level of troponin T was higher on DSS group than dengue hemorrhagic fever without shock group because on DSS occurs to stress caused by hypoperfusion. But the level of troponin T between two groups within normal limits, not found cardiac disorder such as myocarditis on DHF. VL - 3 IS - 4 ER -
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