Background: Acne Vulgaris (AV) is a chronic inflammatory and multifactorial disease involving the pilosebaceous unit. Androgen hormone plays an important role in the pathogenesis of acne. Objective: This study aims to determine the relationship of free testosterone concentration with the severity of acne vulgaris. Methods: This is an observational study using cross sectional design. This study conducted in Dr. Wahidin Sudirohusodo hospital, Hasanuddin University hospital, and other hospital networks and Prodia laboratory in Makassar starting from January until February 2015. The study samples are 42 patients who met the study criteria. There are 32 patients with AV who have been diagnosed clinically and 10 patients with non AV as a control group. Results: The free testosterone concentration and sebum levels in the AV group are higher compared to the control group (p<0.005). This study obtained that there is no significant difference of free testosterone concentration and sebum levels according to the AV levels (p>0.005), but there is a correlation between the free testosterone concentration with the increased of sebum levels. It is mean that even the free testosterone concentration and sebum levels are increased, the acne vulgaris is not necessarily severe, but the increased of free testosterone concentration makes the sebum levels increased. Conclusions: The free testosterone concentration and sebum levels are higher in the acne vulgaris group than the control group. There is no significant relationship of free testosterone concentration with acne vulgaris with p>0.05.
| Published in | American Journal of Clinical and Experimental Medicine (Volume 3, Issue 2) |
| DOI | 10.11648/j.ajcem.20150302.15 |
| Page(s) | 73-77 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Free Testosterone, Sebum Levels, Acne Vulgaris
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APA Style
Andi Fausiah Abdullah, Anis Irawan Anwar, Faridha Ilyas, Sri Vitayani Muchtar, Burhanuddin Bahar, et al. (2015). The Relationship of Salivary Free Testosterone Concentration with Acne Vulgaris. American Journal of Clinical and Experimental Medicine, 3(2), 73-77. https://doi.org/10.11648/j.ajcem.20150302.15
ACS Style
Andi Fausiah Abdullah; Anis Irawan Anwar; Faridha Ilyas; Sri Vitayani Muchtar; Burhanuddin Bahar, et al. The Relationship of Salivary Free Testosterone Concentration with Acne Vulgaris. Am. J. Clin. Exp. Med. 2015, 3(2), 73-77. doi: 10.11648/j.ajcem.20150302.15
AMA Style
Andi Fausiah Abdullah, Anis Irawan Anwar, Faridha Ilyas, Sri Vitayani Muchtar, Burhanuddin Bahar, et al. The Relationship of Salivary Free Testosterone Concentration with Acne Vulgaris. Am J Clin Exp Med. 2015;3(2):73-77. doi: 10.11648/j.ajcem.20150302.15
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Download@article{10.11648/j.ajcem.20150302.15,
author = {Andi Fausiah Abdullah and Anis Irawan Anwar and Faridha Ilyas and Sri Vitayani Muchtar and Burhanuddin Bahar and Andi Makbul Aman},
title = {The Relationship of Salivary Free Testosterone Concentration with Acne Vulgaris},
journal = {American Journal of Clinical and Experimental Medicine},
volume = {3},
number = {2},
pages = {73-77},
doi = {10.11648/j.ajcem.20150302.15},
url = {https://doi.org/10.11648/j.ajcem.20150302.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20150302.15},
abstract = {Background: Acne Vulgaris (AV) is a chronic inflammatory and multifactorial disease involving the pilosebaceous unit. Androgen hormone plays an important role in the pathogenesis of acne. Objective: This study aims to determine the relationship of free testosterone concentration with the severity of acne vulgaris. Methods: This is an observational study using cross sectional design. This study conducted in Dr. Wahidin Sudirohusodo hospital, Hasanuddin University hospital, and other hospital networks and Prodia laboratory in Makassar starting from January until February 2015. The study samples are 42 patients who met the study criteria. There are 32 patients with AV who have been diagnosed clinically and 10 patients with non AV as a control group. Results: The free testosterone concentration and sebum levels in the AV group are higher compared to the control group (p0.005), but there is a correlation between the free testosterone concentration with the increased of sebum levels. It is mean that even the free testosterone concentration and sebum levels are increased, the acne vulgaris is not necessarily severe, but the increased of free testosterone concentration makes the sebum levels increased. Conclusions: The free testosterone concentration and sebum levels are higher in the acne vulgaris group than the control group. There is no significant relationship of free testosterone concentration with acne vulgaris with p>0.05.},
year = {2015}
}
TY - JOUR T1 - The Relationship of Salivary Free Testosterone Concentration with Acne Vulgaris AU - Andi Fausiah Abdullah AU - Anis Irawan Anwar AU - Faridha Ilyas AU - Sri Vitayani Muchtar AU - Burhanuddin Bahar AU - Andi Makbul Aman Y1 - 2015/04/10 PY - 2015 N1 - https://doi.org/10.11648/j.ajcem.20150302.15 DO - 10.11648/j.ajcem.20150302.15 T2 - American Journal of Clinical and Experimental Medicine JF - American Journal of Clinical and Experimental Medicine JO - American Journal of Clinical and Experimental Medicine SP - 73 EP - 77 PB - Science Publishing Group SN - 2330-8133 UR - https://doi.org/10.11648/j.ajcem.20150302.15 AB - Background: Acne Vulgaris (AV) is a chronic inflammatory and multifactorial disease involving the pilosebaceous unit. Androgen hormone plays an important role in the pathogenesis of acne. Objective: This study aims to determine the relationship of free testosterone concentration with the severity of acne vulgaris. Methods: This is an observational study using cross sectional design. This study conducted in Dr. Wahidin Sudirohusodo hospital, Hasanuddin University hospital, and other hospital networks and Prodia laboratory in Makassar starting from January until February 2015. The study samples are 42 patients who met the study criteria. There are 32 patients with AV who have been diagnosed clinically and 10 patients with non AV as a control group. Results: The free testosterone concentration and sebum levels in the AV group are higher compared to the control group (p0.005), but there is a correlation between the free testosterone concentration with the increased of sebum levels. It is mean that even the free testosterone concentration and sebum levels are increased, the acne vulgaris is not necessarily severe, but the increased of free testosterone concentration makes the sebum levels increased. Conclusions: The free testosterone concentration and sebum levels are higher in the acne vulgaris group than the control group. There is no significant relationship of free testosterone concentration with acne vulgaris with p>0.05. VL - 3 IS - 2 ER -
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