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Effect of Vitamin B6 and Acupressure on Vomiting Symptoms in Pregnant Women with Hyperemesis Gravidarum

Received: 16 November 2020     Accepted: 7 December 2020     Published: 22 January 2021
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Abstract

Introduction: Hyperemesis Gravidarum (HG) is a common early pregnancy syndrome that usually occurs around 6 weeks of pregnancy. The patient may cause dehydration, electrolyte metabolism disorders and abnormal fat metabolism, causing increased risk of pregnancy-induced. Objective: The effects of vitamin B and acupressure application combined with psychological adjuvant therapy on vomiting symptoms and mental health in pregnant women with severe vomiting. Methods: Study Type: Randomized Control Trial Duration of Study: Twelve Months from January 2019 to December 2019 Sampling Technique: The data has been collected from the subject index coming to the gynecology OPD of Gulab Devi Teaching Hospital, Lahore, Pakistan. Control group: aged 20 to 37 years, with an average of (26.12±2.44) years; 8 to 17 weeks of gestation, with an average of (9.18±1.77) weeks. Sample Selection Inclusion Criteria: All persons who have 1) meet the diagnostic criteria for HG; 2) 20 to 40 years of age; 3) both signed informed consent. Exclusion Criteria: vomiting caused by medical diseases such as hydatidiform mole, gastrointestinal disease, viral hepatitis, cholecystitis. This study was approved by the Medical Ethics Committee of Gulab Devi Teaching hospital. Pregnant women who were enrolled were divided into control group and experimental group according to the random number table method, with 48 cases in each group. Study Tools: Questionnaire and Interview Sample size (n)=96. Results: After 7 days of treatment the effective percentage rate in the experimental group was higher as compare to the control group in terms of clinical efficacy, SAS and SDS scores, antiemetic and hospitalization time and cost was much lower and within limits in the experimental group as compare to control group. Discussion: In addition to physiological treatment such as fluid replacement, psychological treatment should not be ignored. Conclusion: vitamin B6 and acupressure application combined with psychological adjunctive treatment of HG had a significant effect and could significantly relieve pregnant women Anxiety, depression and promote the recovery of pregnant women.

Published in American Journal of Biomedical and Life Sciences (Volume 9, Issue 1)
DOI 10.11648/j.ajbls.20210901.14
Page(s) 29-35
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Hyperemesis Gravidarum, VitaminB6, Acupressure Application, Psychological Adjuvant Therapy

References
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[2] Wen Mingzhu, Deng Shumao, Lan Tian, et al. Relevant clinical study on the detection of Helicobacter pylori infection in the prevention of hyperemesis gravidarum during the 14C urea breath test. Contemporary Medicine, 2017; 23 (16): 21-22.
[3] Yang Hongping. Acupressure application combined with fluid replacement for the treatment of severe vomiting due to weak spleen and stomach. Journal of Changchun University of Traditional Chinese Medicine, 2016; 32 (6): 1249-1251.
[4] Tara F, Bahrami-Taghanaki H, Amini Ghalandarabad M, Zand-Kargar Z, Azizi H, Esmaily H, Azizi H. The Effect of Acupressure on the Severity of Nausea, Vomiting, and Retching in Pregnant Women: A Randomized Controlled Trial. Complement Med Res. 2020; 27 (4): 252-259.
[5] Adlan AS, Chooi KY, Mat Adenan NA. Acupressure as adjuvant treatment for the inpatient management of nausea and vomiting in early pregnancy: A double-blind randomized controlled trial. J Obstet Gynaecol Res. 2017 Apr; 43 (4): 662-668.
[6] Gadsby R, Rawson V, Dziadulewicz E, Rousseau B, Collings H. Nausea and vomiting of pregnancy and resource implications: the NVP Impact Study. Br J Gen Pract. 2019 Mar; 69 (680): 217-223.
[7] Ostenfeld A, Petersen TS, Futtrup TB, Andersen JT, Jensen AK, Westergaard HB, Pedersen LH, Løkkegaard ECL. Validating the effect of Ondansetron and Mirtazapine In Treating hyperemesis gravidarum (VOMIT): protocol for a randomised placebo-controlled trial. BMJ Open. 2020 Mar 24; 10 (3): e034712.
[8] McParlin C, O'Donnell A, Robson SC, Beyer F, Moloney E, Bryant A, Bradley J, Muirhead CR, Nelson-Piercy C, Newbury-Birch D, Norman J, Shaw C, Simpson E, Swallow B, Yates L, Vale L. Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review. JAMA. 2016 Oct 4; 316 (13): 1392-1401.
[9] Obstetrics Group, Obstetrics and Gynecology Branch, Chinese Medical Association. Expert consensus on diagnosis and clinical management of hyperemesis gravidarum (2015). Chinese Journal of Obstetrics and Gynecology, 2015; 50 (11): 801-804.
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[11] Bai Runfang, Zhang Ya, Yang Chunrong. Comparison of nursing effect of Morita therapy in patients with hyperemesis gravidarum. Nursing Research, 2017, 31 (16): 2042-2045.
[12] Chen Wenxiu, Zhang Yuxia. Efficacy analysis of different administration routes of vitamin B6 in treating hyperemesis during pregnancy. Journal of Bengbu Medical College, 2016; 41 (1): 52-54.
[13] Youchun Hu, Adwoa N. Amoah, Han Zhang, Rong Fu, Yanfang Qiu, Yuan Cao, Yafei Sun, Huanan Chen, Yanhua Liu & Quanjun Lyu. Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis, The Journal of Maternal-Fetal & Neonatal Medicine. 2020. DOI: 10.1080/14767058.2020.1712714.
[14] Jia Bihui, Lv Rongxiang, Guo Fengying. Effects of psychological nursing on functional dyspepsia and bad mood. Chinese Journal of Health Psychology. 2013; 21 (9): 1360-1362.
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[16] Tang Zhiqin. Risk factors related to severe vomiting in early pregnancy and its effect on pregnancy outcome. Hua Xia Medical Science. 2015; 28 (5): 129-131.
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Cite This Article
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    Hamid Mahmood, Talmeez Zaib Shah, Sohail Rasool, Ammara Waqar, Zia-ul-Miraj, et al. (2021). Effect of Vitamin B6 and Acupressure on Vomiting Symptoms in Pregnant Women with Hyperemesis Gravidarum. American Journal of Biomedical and Life Sciences, 9(1), 29-35. https://doi.org/10.11648/j.ajbls.20210901.14

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    ACS Style

    Hamid Mahmood; Talmeez Zaib Shah; Sohail Rasool; Ammara Waqar; Zia-ul-Miraj, et al. Effect of Vitamin B6 and Acupressure on Vomiting Symptoms in Pregnant Women with Hyperemesis Gravidarum. Am. J. Biomed. Life Sci. 2021, 9(1), 29-35. doi: 10.11648/j.ajbls.20210901.14

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    AMA Style

    Hamid Mahmood, Talmeez Zaib Shah, Sohail Rasool, Ammara Waqar, Zia-ul-Miraj, et al. Effect of Vitamin B6 and Acupressure on Vomiting Symptoms in Pregnant Women with Hyperemesis Gravidarum. Am J Biomed Life Sci. 2021;9(1):29-35. doi: 10.11648/j.ajbls.20210901.14

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  • @article{10.11648/j.ajbls.20210901.14,
      author = {Hamid Mahmood and Talmeez Zaib Shah and Sohail Rasool and Ammara Waqar and Zia-ul-Miraj and Zafar Hayat Maken and Awais Gohar and Abdul Rauf},
      title = {Effect of Vitamin B6 and Acupressure on Vomiting Symptoms in Pregnant Women with Hyperemesis Gravidarum},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {9},
      number = {1},
      pages = {29-35},
      doi = {10.11648/j.ajbls.20210901.14},
      url = {https://doi.org/10.11648/j.ajbls.20210901.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20210901.14},
      abstract = {Introduction: Hyperemesis Gravidarum (HG) is a common early pregnancy syndrome that usually occurs around 6 weeks of pregnancy. The patient may cause dehydration, electrolyte metabolism disorders and abnormal fat metabolism, causing increased risk of pregnancy-induced. Objective: The effects of vitamin B and acupressure application combined with psychological adjuvant therapy on vomiting symptoms and mental health in pregnant women with severe vomiting. Methods: Study Type: Randomized Control Trial Duration of Study: Twelve Months from January 2019 to December 2019 Sampling Technique: The data has been collected from the subject index coming to the gynecology OPD of Gulab Devi Teaching Hospital, Lahore, Pakistan. Control group: aged 20 to 37 years, with an average of (26.12±2.44) years; 8 to 17 weeks of gestation, with an average of (9.18±1.77) weeks. Sample Selection Inclusion Criteria: All persons who have 1) meet the diagnostic criteria for HG; 2) 20 to 40 years of age; 3) both signed informed consent. Exclusion Criteria: vomiting caused by medical diseases such as hydatidiform mole, gastrointestinal disease, viral hepatitis, cholecystitis. This study was approved by the Medical Ethics Committee of Gulab Devi Teaching hospital. Pregnant women who were enrolled were divided into control group and experimental group according to the random number table method, with 48 cases in each group. Study Tools: Questionnaire and Interview Sample size (n)=96. Results: After 7 days of treatment the effective percentage rate in the experimental group was higher as compare to the control group in terms of clinical efficacy, SAS and SDS scores, antiemetic and hospitalization time and cost was much lower and within limits in the experimental group as compare to control group. Discussion: In addition to physiological treatment such as fluid replacement, psychological treatment should not be ignored. Conclusion: vitamin B6 and acupressure application combined with psychological adjunctive treatment of HG had a significant effect and could significantly relieve pregnant women Anxiety, depression and promote the recovery of pregnant women.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Effect of Vitamin B6 and Acupressure on Vomiting Symptoms in Pregnant Women with Hyperemesis Gravidarum
    AU  - Hamid Mahmood
    AU  - Talmeez Zaib Shah
    AU  - Sohail Rasool
    AU  - Ammara Waqar
    AU  - Zia-ul-Miraj
    AU  - Zafar Hayat Maken
    AU  - Awais Gohar
    AU  - Abdul Rauf
    Y1  - 2021/01/22
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ajbls.20210901.14
    DO  - 10.11648/j.ajbls.20210901.14
    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
    SP  - 29
    EP  - 35
    PB  - Science Publishing Group
    SN  - 2330-880X
    UR  - https://doi.org/10.11648/j.ajbls.20210901.14
    AB  - Introduction: Hyperemesis Gravidarum (HG) is a common early pregnancy syndrome that usually occurs around 6 weeks of pregnancy. The patient may cause dehydration, electrolyte metabolism disorders and abnormal fat metabolism, causing increased risk of pregnancy-induced. Objective: The effects of vitamin B and acupressure application combined with psychological adjuvant therapy on vomiting symptoms and mental health in pregnant women with severe vomiting. Methods: Study Type: Randomized Control Trial Duration of Study: Twelve Months from January 2019 to December 2019 Sampling Technique: The data has been collected from the subject index coming to the gynecology OPD of Gulab Devi Teaching Hospital, Lahore, Pakistan. Control group: aged 20 to 37 years, with an average of (26.12±2.44) years; 8 to 17 weeks of gestation, with an average of (9.18±1.77) weeks. Sample Selection Inclusion Criteria: All persons who have 1) meet the diagnostic criteria for HG; 2) 20 to 40 years of age; 3) both signed informed consent. Exclusion Criteria: vomiting caused by medical diseases such as hydatidiform mole, gastrointestinal disease, viral hepatitis, cholecystitis. This study was approved by the Medical Ethics Committee of Gulab Devi Teaching hospital. Pregnant women who were enrolled were divided into control group and experimental group according to the random number table method, with 48 cases in each group. Study Tools: Questionnaire and Interview Sample size (n)=96. Results: After 7 days of treatment the effective percentage rate in the experimental group was higher as compare to the control group in terms of clinical efficacy, SAS and SDS scores, antiemetic and hospitalization time and cost was much lower and within limits in the experimental group as compare to control group. Discussion: In addition to physiological treatment such as fluid replacement, psychological treatment should not be ignored. Conclusion: vitamin B6 and acupressure application combined with psychological adjunctive treatment of HG had a significant effect and could significantly relieve pregnant women Anxiety, depression and promote the recovery of pregnant women.
    VL  - 9
    IS  - 1
    ER  - 

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Author Information
  • Department of Bio-Chemistry, Federal Medical and Dental College, Islamabad, Pakistan

  • Department of Bio-Chemistry, Amna Anyat Medical College, Lahore, Pakistan

  • Forensic Medicine Department, Al-Aleem Medical College, Lahore, Pakistan

  • Quality Enhancement Cell, Al-Aleem Medical College, Lahore, Pakistan

  • Department of Medical Education, Al-Aleem Medical College, Lahore, Pakistan

  • Department of Community Medicine, Federal Medical and Dental College, Islamabad, Pakistan

  • Primary and Secondary Health Department, Government of the Punjab, Lahore, Pakistan

  • Department of Medicine, Al-Aleem Medical College, Lahore, Pakistan

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