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Eucalyptus globulus Oil Versus Bleach Use as Antiseptic Agents in Podoconiosis Treatment: An Interventional Study in Wolaita Zone, Southern Ethiopia

Received: 5 June 2017     Accepted: 19 June 2017     Published: 8 November 2017
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Abstract

Eucalyptus globulus essential oil is widely used for medicinal purpose because of its pharmacological constituents. The present study aimed to use water emulsified E. globulus oil as an antiseptic agent in the treatment protocol of podoconiosis (non-filarial elephantiasis) and compare disease improvement upon E. globulus oil versus bleach (usual antiseptic chemical) use in the treatment protocol. An interventional study was conducted from January to March, 2012 to compare disease improvement on podoconiosis upon using water emulsified E. globulus oil versus bleach-water solution as antiseptic agents in podoconiosis treatment. Forty podoconiosis patients purposely selected and randomly allocated into intervention (E. globulus oil) group and comparison (bleach) group with matched clinical stage of podoconiosis. After the baseline data recording, home based treatment was started and follow-up had been undertaken every week for 3-month period. The data were analyzed using SPSS version 16 statistical package. The mean clinical stages of the disease among the study participants were 2.72 for the right and 2.80 for the left legs before the treatment start. Seventeen (32.5%) of patients suffered from the disease for more than 25 years. For all the outcomes measured at the end of study period, the individual treatment effects of eucalyptus oil and bleach antiseptic agents were compared and the result showed no significant difference. Hence, eucalyptus oil emulsified in water can be used as alternative antiseptic agent in podoconiosis treatment protocol.

Published in American Journal of Biomedical and Life Sciences (Volume 5, Issue 6)
DOI 10.11648/j.ajbls.20170506.11
Page(s) 113-118
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Eucalyptus Oil, Podoconiosis, Bleach, Wolaita, Ethiopia

References
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[20] Central Statistical Authority of Ethiopia (CSA) (2012) Population and housing census. Available from http://unstats.un.org/unsd/censuskb20/Attachment489.aspx.
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[22] Desta K, Ashine M, Davey G (2003) "Prevalence of podoconiosis (endemic non-filarial elephantiasis) in Wolaita, Southern Ethiopia". Trop Doct 32: 217- 220.
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  • APA Style

    Bereket Alemayehu, Terefe Gelibo, Zewde Zema Kanche. (2017). Eucalyptus globulus Oil Versus Bleach Use as Antiseptic Agents in Podoconiosis Treatment: An Interventional Study in Wolaita Zone, Southern Ethiopia. American Journal of Biomedical and Life Sciences, 5(6), 113-118. https://doi.org/10.11648/j.ajbls.20170506.11

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    ACS Style

    Bereket Alemayehu; Terefe Gelibo; Zewde Zema Kanche. Eucalyptus globulus Oil Versus Bleach Use as Antiseptic Agents in Podoconiosis Treatment: An Interventional Study in Wolaita Zone, Southern Ethiopia. Am. J. Biomed. Life Sci. 2017, 5(6), 113-118. doi: 10.11648/j.ajbls.20170506.11

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    AMA Style

    Bereket Alemayehu, Terefe Gelibo, Zewde Zema Kanche. Eucalyptus globulus Oil Versus Bleach Use as Antiseptic Agents in Podoconiosis Treatment: An Interventional Study in Wolaita Zone, Southern Ethiopia. Am J Biomed Life Sci. 2017;5(6):113-118. doi: 10.11648/j.ajbls.20170506.11

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  • @article{10.11648/j.ajbls.20170506.11,
      author = {Bereket Alemayehu and Terefe Gelibo and Zewde Zema Kanche},
      title = {Eucalyptus globulus Oil Versus Bleach Use as Antiseptic Agents in Podoconiosis Treatment: An Interventional Study in Wolaita Zone, Southern Ethiopia},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {5},
      number = {6},
      pages = {113-118},
      doi = {10.11648/j.ajbls.20170506.11},
      url = {https://doi.org/10.11648/j.ajbls.20170506.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20170506.11},
      abstract = {Eucalyptus globulus essential oil is widely used for medicinal purpose because of its pharmacological constituents. The present study aimed to use water emulsified E. globulus oil as an antiseptic agent in the treatment protocol of podoconiosis (non-filarial elephantiasis) and compare disease improvement upon E. globulus oil versus bleach (usual antiseptic chemical) use in the treatment protocol. An interventional study was conducted from January to March, 2012 to compare disease improvement on podoconiosis upon using water emulsified E. globulus oil versus bleach-water solution as antiseptic agents in podoconiosis treatment. Forty podoconiosis patients purposely selected and randomly allocated into intervention (E. globulus oil) group and comparison (bleach) group with matched clinical stage of podoconiosis. After the baseline data recording, home based treatment was started and follow-up had been undertaken every week for 3-month period. The data were analyzed using SPSS version 16 statistical package. The mean clinical stages of the disease among the study participants were 2.72 for the right and 2.80 for the left legs before the treatment start. Seventeen (32.5%) of patients suffered from the disease for more than 25 years. For all the outcomes measured at the end of study period, the individual treatment effects of eucalyptus oil and bleach antiseptic agents were compared and the result showed no significant difference. Hence, eucalyptus oil emulsified in water can be used as alternative antiseptic agent in podoconiosis treatment protocol.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Eucalyptus globulus Oil Versus Bleach Use as Antiseptic Agents in Podoconiosis Treatment: An Interventional Study in Wolaita Zone, Southern Ethiopia
    AU  - Bereket Alemayehu
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    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
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    PB  - Science Publishing Group
    SN  - 2330-880X
    UR  - https://doi.org/10.11648/j.ajbls.20170506.11
    AB  - Eucalyptus globulus essential oil is widely used for medicinal purpose because of its pharmacological constituents. The present study aimed to use water emulsified E. globulus oil as an antiseptic agent in the treatment protocol of podoconiosis (non-filarial elephantiasis) and compare disease improvement upon E. globulus oil versus bleach (usual antiseptic chemical) use in the treatment protocol. An interventional study was conducted from January to March, 2012 to compare disease improvement on podoconiosis upon using water emulsified E. globulus oil versus bleach-water solution as antiseptic agents in podoconiosis treatment. Forty podoconiosis patients purposely selected and randomly allocated into intervention (E. globulus oil) group and comparison (bleach) group with matched clinical stage of podoconiosis. After the baseline data recording, home based treatment was started and follow-up had been undertaken every week for 3-month period. The data were analyzed using SPSS version 16 statistical package. The mean clinical stages of the disease among the study participants were 2.72 for the right and 2.80 for the left legs before the treatment start. Seventeen (32.5%) of patients suffered from the disease for more than 25 years. For all the outcomes measured at the end of study period, the individual treatment effects of eucalyptus oil and bleach antiseptic agents were compared and the result showed no significant difference. Hence, eucalyptus oil emulsified in water can be used as alternative antiseptic agent in podoconiosis treatment protocol.
    VL  - 5
    IS  - 6
    ER  - 

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Author Information
  • Biomedical Science Division, Biology Department, College of Natural and Computational Sciences, Wolaita Sodo University, Wolaita Sodo, Ethiopia

  • Health System Research Directorate, Ethiopian Public Health Institute, Addis Ababa, Ethiopia

  • Department of Pharmacy, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia

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