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Current Status of Microsporidium Among Hospitalised Human Immunodeficiency Virus (HIV/AIDS) Infected Patients, Federal Medical Centre, Keffi, Nigeria

Published in Advances (Volume 4, Issue 3)
Received: 30 June 2023     Accepted: 25 July 2023     Published: 25 September 2023
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Abstract

Microsporidia are obligate intracellular parasitic fungi causing chronic diarrhea, particularly among immunocompromised patients. Microsporidial infections have been recognized as an increasingly important infection, particularly among those hospitalised with HIV/AIDS infected patients at the federal medical centre (FMC), Keffi, Nasarawa State. One health facility was used to engage HIV/AIDS infected patient accessing antiretroviral therapy (ART) to identify the presence of microsporidium and to determine the associated risk factors. 252 stool samples were examined for microsporidial spores by modified giemsa staining technique. The overall prevalence rate of 15.08% was recorded. Based on age group, microsporidia infection was common among patients aged between 61-70years 15.0% while sex-related, the male had 30.43% rate of infection. Though, marital status, occupation, and widow/widower had 15.79% and artisans (33.33%) respectively. The vulnerability was determined by their fate and status. However, chi-square result showed no significant relationship observed (P>0.05) between the age, and sex- distribution of microsporidium. The proportion among occupation and marital related distribution of microsporidium among HIV/AIDS infected patients were diarrhoic. In relation to viral load, all positive HIV/AIDS infected patients with microsporidia spore had viral load above normal. Twenty-five (25) HIV/AIDS infected patients had 10,000ml/viral load in replicates. Microsporidium is therefore, identified and recognized as an invasive opportunistic infection among HIV/AIDS infected patients which should be considered in a routine checks among HIV/AIDS infected patients.

Published in Advances (Volume 4, Issue 3)
DOI 10.11648/j.advances.20230403.14
Page(s) 111-115
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Current Microsporidium Status, Among Hospitalised, Hiv/Aids, Infected Patients, Medical Centre

References
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[7] Eligio-Garcia L, Cano-Estrada A, Cruz C, Jimenez-CardosoE. (2016). Association of viral load and CD4+ count with infection of intestinal emerging parasites in HIV patients. Journal of AIDS and Clinical Research. 7: 644.
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  • APA Style

    Juliana Bitrus, Yako Andrew Bmibmitawuza, Ombugadu Ruth Jamila, Tongjura Joseph. (2023). Current Status of Microsporidium Among Hospitalised Human Immunodeficiency Virus (HIV/AIDS) Infected Patients, Federal Medical Centre, Keffi, Nigeria. Advances, 4(3), 111-115. https://doi.org/10.11648/j.advances.20230403.14

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    ACS Style

    Juliana Bitrus; Yako Andrew Bmibmitawuza; Ombugadu Ruth Jamila; Tongjura Joseph. Current Status of Microsporidium Among Hospitalised Human Immunodeficiency Virus (HIV/AIDS) Infected Patients, Federal Medical Centre, Keffi, Nigeria. Advances. 2023, 4(3), 111-115. doi: 10.11648/j.advances.20230403.14

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    AMA Style

    Juliana Bitrus, Yako Andrew Bmibmitawuza, Ombugadu Ruth Jamila, Tongjura Joseph. Current Status of Microsporidium Among Hospitalised Human Immunodeficiency Virus (HIV/AIDS) Infected Patients, Federal Medical Centre, Keffi, Nigeria. Advances. 2023;4(3):111-115. doi: 10.11648/j.advances.20230403.14

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  • @article{10.11648/j.advances.20230403.14,
      author = {Juliana Bitrus and Yako Andrew Bmibmitawuza and Ombugadu Ruth Jamila and Tongjura Joseph},
      title = {Current Status of Microsporidium Among Hospitalised Human Immunodeficiency Virus (HIV/AIDS) Infected Patients, Federal Medical Centre, Keffi, Nigeria},
      journal = {Advances},
      volume = {4},
      number = {3},
      pages = {111-115},
      doi = {10.11648/j.advances.20230403.14},
      url = {https://doi.org/10.11648/j.advances.20230403.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.advances.20230403.14},
      abstract = {Microsporidia are obligate intracellular parasitic fungi causing chronic diarrhea, particularly among immunocompromised patients. Microsporidial infections have been recognized as an increasingly important infection, particularly among those hospitalised with HIV/AIDS infected patients at the federal medical centre (FMC), Keffi, Nasarawa State. One health facility was used to engage HIV/AIDS infected patient accessing antiretroviral therapy (ART) to identify the presence of microsporidium and to determine the associated risk factors. 252 stool samples were examined for microsporidial spores by modified giemsa staining technique. The overall prevalence rate of 15.08% was recorded. Based on age group, microsporidia infection was common among patients aged between 61-70years 15.0% while sex-related, the male had 30.43% rate of infection. Though, marital status, occupation, and widow/widower had 15.79% and artisans (33.33%) respectively. The vulnerability was determined by their fate and status. However, chi-square result showed no significant relationship observed (P>0.05) between the age, and sex- distribution of microsporidium. The proportion among occupation and marital related distribution of microsporidium among HIV/AIDS infected patients were diarrhoic. In relation to viral load, all positive HIV/AIDS infected patients with microsporidia spore had viral load above normal. Twenty-five (25) HIV/AIDS infected patients had 10,000ml/viral load in replicates. Microsporidium is therefore, identified and recognized as an invasive opportunistic infection among HIV/AIDS infected patients which should be considered in a routine checks among HIV/AIDS infected patients.},
     year = {2023}
    }
    

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    AB  - Microsporidia are obligate intracellular parasitic fungi causing chronic diarrhea, particularly among immunocompromised patients. Microsporidial infections have been recognized as an increasingly important infection, particularly among those hospitalised with HIV/AIDS infected patients at the federal medical centre (FMC), Keffi, Nasarawa State. One health facility was used to engage HIV/AIDS infected patient accessing antiretroviral therapy (ART) to identify the presence of microsporidium and to determine the associated risk factors. 252 stool samples were examined for microsporidial spores by modified giemsa staining technique. The overall prevalence rate of 15.08% was recorded. Based on age group, microsporidia infection was common among patients aged between 61-70years 15.0% while sex-related, the male had 30.43% rate of infection. Though, marital status, occupation, and widow/widower had 15.79% and artisans (33.33%) respectively. The vulnerability was determined by their fate and status. However, chi-square result showed no significant relationship observed (P>0.05) between the age, and sex- distribution of microsporidium. The proportion among occupation and marital related distribution of microsporidium among HIV/AIDS infected patients were diarrhoic. In relation to viral load, all positive HIV/AIDS infected patients with microsporidia spore had viral load above normal. Twenty-five (25) HIV/AIDS infected patients had 10,000ml/viral load in replicates. Microsporidium is therefore, identified and recognized as an invasive opportunistic infection among HIV/AIDS infected patients which should be considered in a routine checks among HIV/AIDS infected patients.
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Author Information
  • Department of Zoology, Nasarawa State University, Keffi, Nigeria

  • Department of Zoology, Nasarawa State University, Keffi, Nigeria

  • Department of Zoology, Nasarawa State University, Keffi, Nigeria

  • Department of Zoology, Nasarawa State University, Keffi, Nigeria

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