Objective To observe and evaluate the effect of β- hydroxy-β- methylbutyric acid (HMB) on phase angle (PA) in maintenance hemodialysis (MHD) patients. Methods From March 2018 to August 2019, 64 patients who received maintenance hemodialysis, at Chengdu Fifth People's Hospital, were selected as subjects, and they were divided into experimental group and control group with single center, random, single dose, single blind control design, and 32 patients in each group. HMB intervention was performed in the trial group and placebo in the control group for 12 weeks. Human component analysis (Inbody S770) was performed before and after intervention in the two groups to observe the change of phase angle. Scored Patient-Generated Subjective Global Assessment (SGA) and Malnutrition Inflammatory Score (MIS) were used to assess the nutritional status of MHD patients before and after group entry, to observe the correlation of its numerical change and the phase angle. Results The PA, SGA, MIS of the experimental group was significantly higher (p<0.05) than that of the control group (p<0.05), and the test group increased better than the control group (p<0.05). Positive correlation between PA and SGA, MIS (p<0.05). Conclusions By giving patients complementary HMB, to improve patient nutritional status, to improve the patient phase angle, and improve the patient prognosis.
Published in | Science Discovery (Volume 9, Issue 4) |
DOI | 10.11648/j.sd.20210904.14 |
Page(s) | 150-154 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2021. Published by Science Publishing Group |
Phase Angle, β- hydroxy-β-methyl Butyric Acid, Maintenance Hemodialysis
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APA Style
Liang Qingyue, Wang Zhong, Zong Xueping, Diao Yanqing, Cai Ping, et al. (2021). Effect of HMB on Phase Angle of Maintenance Hemodialysis Patients. Science Discovery, 9(4), 150-154. https://doi.org/10.11648/j.sd.20210904.14
ACS Style
Liang Qingyue; Wang Zhong; Zong Xueping; Diao Yanqing; Cai Ping, et al. Effect of HMB on Phase Angle of Maintenance Hemodialysis Patients. Sci. Discov. 2021, 9(4), 150-154. doi: 10.11648/j.sd.20210904.14
AMA Style
Liang Qingyue, Wang Zhong, Zong Xueping, Diao Yanqing, Cai Ping, et al. Effect of HMB on Phase Angle of Maintenance Hemodialysis Patients. Sci Discov. 2021;9(4):150-154. doi: 10.11648/j.sd.20210904.14
@article{10.11648/j.sd.20210904.14, author = {Liang Qingyue and Wang Zhong and Zong Xueping and Diao Yanqing and Cai Ping and Li Honglie and Hu Liping}, title = {Effect of HMB on Phase Angle of Maintenance Hemodialysis Patients}, journal = {Science Discovery}, volume = {9}, number = {4}, pages = {150-154}, doi = {10.11648/j.sd.20210904.14}, url = {https://doi.org/10.11648/j.sd.20210904.14}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20210904.14}, abstract = {Objective To observe and evaluate the effect of β- hydroxy-β- methylbutyric acid (HMB) on phase angle (PA) in maintenance hemodialysis (MHD) patients. Methods From March 2018 to August 2019, 64 patients who received maintenance hemodialysis, at Chengdu Fifth People's Hospital, were selected as subjects, and they were divided into experimental group and control group with single center, random, single dose, single blind control design, and 32 patients in each group. HMB intervention was performed in the trial group and placebo in the control group for 12 weeks. Human component analysis (Inbody S770) was performed before and after intervention in the two groups to observe the change of phase angle. Scored Patient-Generated Subjective Global Assessment (SGA) and Malnutrition Inflammatory Score (MIS) were used to assess the nutritional status of MHD patients before and after group entry, to observe the correlation of its numerical change and the phase angle. Results The PA, SGA, MIS of the experimental group was significantly higher (p<0.05) than that of the control group (p<0.05), and the test group increased better than the control group (p<0.05). Positive correlation between PA and SGA, MIS (p<0.05). Conclusions By giving patients complementary HMB, to improve patient nutritional status, to improve the patient phase angle, and improve the patient prognosis.}, year = {2021} }
TY - JOUR T1 - Effect of HMB on Phase Angle of Maintenance Hemodialysis Patients AU - Liang Qingyue AU - Wang Zhong AU - Zong Xueping AU - Diao Yanqing AU - Cai Ping AU - Li Honglie AU - Hu Liping Y1 - 2021/06/04 PY - 2021 N1 - https://doi.org/10.11648/j.sd.20210904.14 DO - 10.11648/j.sd.20210904.14 T2 - Science Discovery JF - Science Discovery JO - Science Discovery SP - 150 EP - 154 PB - Science Publishing Group SN - 2331-0650 UR - https://doi.org/10.11648/j.sd.20210904.14 AB - Objective To observe and evaluate the effect of β- hydroxy-β- methylbutyric acid (HMB) on phase angle (PA) in maintenance hemodialysis (MHD) patients. Methods From March 2018 to August 2019, 64 patients who received maintenance hemodialysis, at Chengdu Fifth People's Hospital, were selected as subjects, and they were divided into experimental group and control group with single center, random, single dose, single blind control design, and 32 patients in each group. HMB intervention was performed in the trial group and placebo in the control group for 12 weeks. Human component analysis (Inbody S770) was performed before and after intervention in the two groups to observe the change of phase angle. Scored Patient-Generated Subjective Global Assessment (SGA) and Malnutrition Inflammatory Score (MIS) were used to assess the nutritional status of MHD patients before and after group entry, to observe the correlation of its numerical change and the phase angle. Results The PA, SGA, MIS of the experimental group was significantly higher (p<0.05) than that of the control group (p<0.05), and the test group increased better than the control group (p<0.05). Positive correlation between PA and SGA, MIS (p<0.05). Conclusions By giving patients complementary HMB, to improve patient nutritional status, to improve the patient phase angle, and improve the patient prognosis. VL - 9 IS - 4 ER -