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Challenges of Perioperative Management and Outcome of Neonates with Gastroschisis in a Tertiary Hospital in Southern Nigeria

Received: 20 August 2026     Accepted: 31 August 2026     Published: 20 September 2026
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Abstract

Gastroschisis is a congenital full thickness anterior abdominal wall defect with exposure of intraabdominal content of varying degree and affected neonates are at risk of fluid loss, sepsis, hypothermia, and metabolic derangements. Perioperative management plays a pivotal role in stabilizing these newborns and influences better clinical outcome. The aim of this 3-year retrospective study was to assess the relationship between the age at presentation, type of anaesthesia rendered and outcomes recorded among neonates diagnosed with gastroschisis as well as to highlight the challenges associated with the perioperative management. Methods: This study is a three-year retrospective review (2023-2025) of neonates with gastroschisis managed at the University of Benin Teaching Hospital (UBTH). Hospital records of neonates with gastroschisis who underwent surgical repair within the study period were retrieved. Data extracted were demographic characteristics, clinical diagnosis, surgical procedures, anesthetic technique, length of hospital stay and outcome. Results: Nine cases were reviewed, 5 Females (55.6%) and 4 males (44.4%). The age at presentation ranged from 2 hours to 48hours. Isolated gastroschisis alone accounted for 77.8% of cases, while gastroschisis with intestinal atresia and gastroschisis with gangrenous bowel accounted for 11.1% respectively. General anesthesia was used for all patients. Length of postoperative hospital stay ranged from 3 to 16 days. Mortality was recorded in all patients, with highest number of mortality (33.3%) on the 10th day on admission. Conclusion: We therefore emphasize the high rate of mortality among patients with gastroschisis and highlight the need for adequate perioperative management of neonates with gastroschisis.

Published in Research and Innovation (Volume 2, Issue 5)
DOI 10.11648/j.ri.20260205.11
Page(s) 274-279
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2026. Published by Science Publishing Group

Keywords

Gastroschisis, Management, Outcome, Perioperative

References
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[2] Baird, R., Puligandla, P. S., Skarsgard, E. D., & Laberge, J. M. (2017). Infectious complications in the management of gastroschisis. Journal of Pediatric Surgery, 52(7), 1126-1130.
[3] Feldkamp, M. L., Carey, J. C., Sadler, T. W., & Rasmussen, S. A. (2017). Etiology and clinical presentation of gastroschisis. American Journal of Medical Genetics Part C, 175(2), 294-304.
[4] Ameh, E. A., Chirdan, L. B., & Nmadu, P. T. (2019). Neonatal surgery in sub-Saharan Africa: A review of challenges and outcomes. Pediatric Surgery International, 35(4), 435-441.
[5] Abdur-Rahman, L. O., Adeniran, J. O., Taiwo, J. O., & Nasir, A. A. (2013). Challenges and outcomes of management of anterior abdominal wall defects in a Nigerian tertiary hospital. African Journal of Paediatric Surgery, 10(3), 230-234.
[6] Walker, S. M., Yaksh, T. L., & Fitzgerald, M. (2014). Neonatal pain and anesthesia: Clinical considerations. Pain, 155(10), 1953-1960.
[7] Williams, G. D., & Walker, S. M. (2015). Anesthetic management of neonatal surgical emergencies. Anesthesia & Analgesia, 121(2), 386-400.
[8] Rustemor D, Sakuor Z, Kucherbayeva, Shayakhmetor and Blial R. (2025). Gastroschisis: Diagnosis, Prognosis and Treatment Opyions. Frontiers in Pediatrics. 13: 1717874.
[9] Martins BMR, Abren I, Meio MDB, Moreira MEL; Gastroschisis in the neonatal period: a prospective case-series in a Brazillian referral center. Journal of Pediatric Surgery. (2020) 55 (8): 1546-1551.
[10] Verma A, Yadar DK, Singh JK, Anand S. Challenges in Managing Closed Gastroschisis: Addressing a rare and complex variant of abdominal wall defect. Journal of Indian Association ofPediatric Surgery. (2025) 30(2): 183-189.
[11] Yap A., Halid S. I, Ukwu N, Laverde R, Park P, Klazura G., and Ameh E. A (2024). Cost-effectiveness of a pediatric operating room installation in Sub-Sahara Africa. PLOS Global Public Health. 4(3), e0001748.
[12] Md Zamil Hossain, Md Nowshad Ali, Shah Md. Alisan Shalid, Shantona Rani Paul, Abdulla Al Mamun. Burden of Neonatal Surgical Conditions on their Outcomes in a resource limited Tertiary Hospital in Bangladesh. Scolars Journal of Applied Medical Sciences. 2024 jun12(6): 776-785.
[13] Purbey OP, Rahul SK, Keshri R, Chaubey D. An approach to identity high-risk neonatal surgical cases to optimize postoperative results. Surgery on Children. 2025; 2(3): 109-113.
[14] Akpanudo Emem I, Ituen Monday A., Akpaette Inioton C., Eyo Aniekpeno E., Emmanuel Eti-Inyene M. Improvised Adaptations in Neonatal Surgery: Experience From A Resource-Constrianed Tertiary Hospital in Nigeria. Annals of Medicine and Medical Sciences 2025, 4(10): 912-917.
[15] Mengistu WE, Matebe Yh, Tadesse MS, et al. Outcome and Associated Factors of Neonatal Surgeries at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, A &-year Period. Sage Open Pediatrics. 2025; 12.
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  • APA Style

    Inegbenosun, I., Osaheni, O. (2026). Challenges of Perioperative Management and Outcome of Neonates with Gastroschisis in a Tertiary Hospital in Southern Nigeria. Research and Innovation, 2(5), 274-279. https://doi.org/10.11648/j.ri.20260205.11

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    ACS Style

    Inegbenosun, I.; Osaheni, O. Challenges of Perioperative Management and Outcome of Neonates with Gastroschisis in a Tertiary Hospital in Southern Nigeria. Res. Innovation 2026, 2(5), 274-279. doi: 10.11648/j.ri.20260205.11

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    AMA Style

    Inegbenosun I, Osaheni O. Challenges of Perioperative Management and Outcome of Neonates with Gastroschisis in a Tertiary Hospital in Southern Nigeria. Res Innovation. 2026;2(5):274-279. doi: 10.11648/j.ri.20260205.11

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  • @article{10.11648/j.ri.20260205.11,
      author = {Iluobe Inegbenosun and Osayomwanbo Osaheni},
      title = {Challenges of Perioperative Management and Outcome of Neonates with Gastroschisis in a Tertiary Hospital in Southern Nigeria},
      journal = {Research and Innovation},
      volume = {2},
      number = {5},
      pages = {274-279},
      doi = {10.11648/j.ri.20260205.11},
      url = {https://doi.org/10.11648/j.ri.20260205.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ri.20260205.11},
      abstract = {Gastroschisis is a congenital full thickness anterior abdominal wall defect with exposure of intraabdominal content of varying degree and affected neonates are at risk of fluid loss, sepsis, hypothermia, and metabolic derangements. Perioperative management plays a pivotal role in stabilizing these newborns and influences better clinical outcome. The aim of this 3-year retrospective study was to assess the relationship between the age at presentation, type of anaesthesia rendered and outcomes recorded among neonates diagnosed with gastroschisis as well as to highlight the challenges associated with the perioperative management. Methods: This study is a three-year retrospective review (2023-2025) of neonates with gastroschisis managed at the University of Benin Teaching Hospital (UBTH). Hospital records of neonates with gastroschisis who underwent surgical repair within the study period were retrieved. Data extracted were demographic characteristics, clinical diagnosis, surgical procedures, anesthetic technique, length of hospital stay and outcome. Results: Nine cases were reviewed, 5 Females (55.6%) and 4 males (44.4%). The age at presentation ranged from 2 hours to 48hours. Isolated gastroschisis alone accounted for 77.8% of cases, while gastroschisis with intestinal atresia and gastroschisis with gangrenous bowel accounted for 11.1% respectively. General anesthesia was used for all patients. Length of postoperative hospital stay ranged from 3 to 16 days. Mortality was recorded in all patients, with highest number of mortality (33.3%) on the 10th day on admission. Conclusion: We therefore emphasize the high rate of mortality among patients with gastroschisis and highlight the need for adequate perioperative management of neonates with gastroschisis.},
     year = {2026}
    }
    

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  • TY  - JOUR
    T1  - Challenges of Perioperative Management and Outcome of Neonates with Gastroschisis in a Tertiary Hospital in Southern Nigeria
    AU  - Iluobe Inegbenosun
    AU  - Osayomwanbo Osaheni
    Y1  - 2026/09/20
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    UR  - https://doi.org/10.11648/j.ri.20260205.11
    AB  - Gastroschisis is a congenital full thickness anterior abdominal wall defect with exposure of intraabdominal content of varying degree and affected neonates are at risk of fluid loss, sepsis, hypothermia, and metabolic derangements. Perioperative management plays a pivotal role in stabilizing these newborns and influences better clinical outcome. The aim of this 3-year retrospective study was to assess the relationship between the age at presentation, type of anaesthesia rendered and outcomes recorded among neonates diagnosed with gastroschisis as well as to highlight the challenges associated with the perioperative management. Methods: This study is a three-year retrospective review (2023-2025) of neonates with gastroschisis managed at the University of Benin Teaching Hospital (UBTH). Hospital records of neonates with gastroschisis who underwent surgical repair within the study period were retrieved. Data extracted were demographic characteristics, clinical diagnosis, surgical procedures, anesthetic technique, length of hospital stay and outcome. Results: Nine cases were reviewed, 5 Females (55.6%) and 4 males (44.4%). The age at presentation ranged from 2 hours to 48hours. Isolated gastroschisis alone accounted for 77.8% of cases, while gastroschisis with intestinal atresia and gastroschisis with gangrenous bowel accounted for 11.1% respectively. General anesthesia was used for all patients. Length of postoperative hospital stay ranged from 3 to 16 days. Mortality was recorded in all patients, with highest number of mortality (33.3%) on the 10th day on admission. Conclusion: We therefore emphasize the high rate of mortality among patients with gastroschisis and highlight the need for adequate perioperative management of neonates with gastroschisis.
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