Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment

Hasyizan Mohamad Hassan; Nurul Ashikin Hasbullah; Saedah Ali; Ruwaida Isa

doi:doi:10.11648/j.ja.20180601.16

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Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment

Hasyizan Mohamad Hassan, Nurul Ashikin Hasbullah, Saedah Ali, Ruwaida Isa

Published in Journal of Anesthesiology (Volume 6, Issue 1)

Received: 14 January 2018 Accepted: 14 May 2018 Published: 4 July 2018

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Abstract

The ideal intraoperative intravenous fluid in paediatric anaesthesia and surgery is still debatable. This is essential to overcome physiological changes to maintain safety and wellbeing of the patient. A new isotonic “balanced solution” (Sterofundin ® ISO) has been introduced to replace existing intraoperative fluid of choice (Ringer’s Lactate). The study aimed to observe any changes in electrolytes and acid base after infusion of each study solutions and to evaluate any post infusion electrolytes and acid base differences between both study solutions. The double blinded randomized control trial involved 141 paediatric patients who were subjected to minor surgical procedure of less than 3 hours were randomized into Ringer’s Lactate or Sterofundin ® ISO group. The electrolytes and acid base parameters were assessed at pre-infusion and post-infusion time. There were significant difference in glucose, potassium (K⁺) and chloride (Cl^-) level between pre-infusion and post-infusion values with those given Ringer’s Lactate. There were also significant different in pH, base excess, glucose, Calcium (Ca²⁺), Chloride (Cl) and lactate level between pre-infusion and post-infusion values with Sterofundin ® ISO. When comparing the mean difference (pre-infusion and post-infusion) between Ringer’s Lactate and Sterofundin ® ISO, calcium (Ca²⁺) is the only electrtolyte which found to be significant (P=0.015) with the values of (Means±SD 0.005±0.07) mmol/L and (Means±SD 0.02±0.06) mmol/L respectively. Both study solutions showed variable effects of electrolytes and acid base parameters and no fluid was found to be superior in paediatric surgical patients underwent minor surgery of less than three hours.

Published in	Journal of Anesthesiology (Volume 6, Issue 1)
DOI	10.11648/j.ja.20180601.16
Page(s)	33-39
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Sterofundin ® ISO, Ringer’s Lactate, Paediatric, Minor Surgery, Electrolytes, Acid-Base Balance

References

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APA Style

Hasyizan Mohamad Hassan, Nurul Ashikin Hasbullah, Saedah Ali, Ruwaida Isa. (2018). Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment. International Journal of Anesthesia and Clinical Medicine, 6(1), 33-39. https://doi.org/10.11648/j.ja.20180601.16

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ACS Style

Hasyizan Mohamad Hassan; Nurul Ashikin Hasbullah; Saedah Ali; Ruwaida Isa. Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment. Int. J. Anesth. Clin. Med. 2018, 6(1), 33-39. doi: 10.11648/j.ja.20180601.16

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AMA Style

Hasyizan Mohamad Hassan, Nurul Ashikin Hasbullah, Saedah Ali, Ruwaida Isa. Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment. Int J Anesth Clin Med. 2018;6(1):33-39. doi: 10.11648/j.ja.20180601.16

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@article{10.11648/j.ja.20180601.16,
  author = {Hasyizan Mohamad Hassan and Nurul Ashikin Hasbullah and Saedah Ali and Ruwaida Isa},
  title = {Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment},
  journal = {International Journal of Anesthesia and Clinical Medicine},
  volume = {6},
  number = {1},
  pages = {33-39},
  doi = {10.11648/j.ja.20180601.16},
  url = {https://doi.org/10.11648/j.ja.20180601.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ja.20180601.16},
  abstract = {The ideal intraoperative intravenous fluid in paediatric anaesthesia and surgery is still debatable. This is essential to overcome physiological changes to maintain safety and wellbeing of the patient. A new isotonic “balanced solution” (Sterofundin ® ISO) has been introduced to replace existing intraoperative fluid of choice (Ringer’s Lactate). The study aimed to observe any changes in electrolytes and acid base after infusion of each study solutions and to evaluate any post infusion electrolytes and acid base differences between both study solutions. The double blinded randomized control trial involved 141 paediatric patients who were subjected to minor surgical procedure of less than 3 hours were randomized into Ringer’s Lactate or Sterofundin ® ISO group. The electrolytes and acid base parameters were assessed at pre-infusion and post-infusion time. There were significant difference in glucose, potassium (K+) and chloride (Cl-) level between pre-infusion and post-infusion values with those given Ringer’s Lactate. There were also significant different in pH, base excess, glucose, Calcium (Ca2+), Chloride (Cl) and lactate level between pre-infusion and post-infusion values with Sterofundin ® ISO. When comparing the mean difference (pre-infusion and post-infusion) between Ringer’s Lactate and Sterofundin ® ISO, calcium (Ca2+) is the only electrtolyte which found to be significant (P=0.015) with the values of (Means±SD 0.005±0.07) mmol/L and (Means±SD 0.02±0.06) mmol/L respectively. Both study solutions showed variable effects of electrolytes and acid base parameters and no fluid was found to be superior in paediatric surgical patients underwent minor surgery of less than three hours.},
 year = {2018}
}

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TY  - JOUR
T1  - Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment
AU  - Hasyizan Mohamad Hassan
AU  - Nurul Ashikin Hasbullah
AU  - Saedah Ali
AU  - Ruwaida Isa
Y1  - 2018/07/04
PY  - 2018
N1  - https://doi.org/10.11648/j.ja.20180601.16
DO  - 10.11648/j.ja.20180601.16
T2  - International Journal of Anesthesia and Clinical Medicine
JF  - International Journal of Anesthesia and Clinical Medicine
JO  - International Journal of Anesthesia and Clinical Medicine
SP  - 33
EP  - 39
PB  - Science Publishing Group
SN  - 2997-2698
UR  - https://doi.org/10.11648/j.ja.20180601.16
AB  - The ideal intraoperative intravenous fluid in paediatric anaesthesia and surgery is still debatable. This is essential to overcome physiological changes to maintain safety and wellbeing of the patient. A new isotonic “balanced solution” (Sterofundin ® ISO) has been introduced to replace existing intraoperative fluid of choice (Ringer’s Lactate). The study aimed to observe any changes in electrolytes and acid base after infusion of each study solutions and to evaluate any post infusion electrolytes and acid base differences between both study solutions. The double blinded randomized control trial involved 141 paediatric patients who were subjected to minor surgical procedure of less than 3 hours were randomized into Ringer’s Lactate or Sterofundin ® ISO group. The electrolytes and acid base parameters were assessed at pre-infusion and post-infusion time. There were significant difference in glucose, potassium (K+) and chloride (Cl-) level between pre-infusion and post-infusion values with those given Ringer’s Lactate. There were also significant different in pH, base excess, glucose, Calcium (Ca2+), Chloride (Cl) and lactate level between pre-infusion and post-infusion values with Sterofundin ® ISO. When comparing the mean difference (pre-infusion and post-infusion) between Ringer’s Lactate and Sterofundin ® ISO, calcium (Ca2+) is the only electrtolyte which found to be significant (P=0.015) with the values of (Means±SD 0.005±0.07) mmol/L and (Means±SD 0.02±0.06) mmol/L respectively. Both study solutions showed variable effects of electrolytes and acid base parameters and no fluid was found to be superior in paediatric surgical patients underwent minor surgery of less than three hours.
VL  - 6
IS  - 1
ER  -

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Author Information

Hasyizan Mohamad Hassan

Department of Anesthesia and Intensive Care, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
Nurul Ashikin Hasbullah

Department of Anesthesia and Intensive Care, Hospital Raja Perempuan Zainab 2, Kota Bharu, Malaysia
Saedah Ali

Department of Anesthesia and Intensive Care, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
Ruwaida Isa

Department of Anesthesia and Intensive Care, Hospital Raja Perempuan Zainab 2, Kota Bharu, Malaysia

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Plain Text BibTeX RIS

APA Style

Hasyizan Mohamad Hassan, Nurul Ashikin Hasbullah, Saedah Ali, Ruwaida Isa. (2018). Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment. International Journal of Anesthesia and Clinical Medicine, 6(1), 33-39. https://doi.org/10.11648/j.ja.20180601.16

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ACS Style

Hasyizan Mohamad Hassan; Nurul Ashikin Hasbullah; Saedah Ali; Ruwaida Isa. Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment. Int. J. Anesth. Clin. Med. 2018, 6(1), 33-39. doi: 10.11648/j.ja.20180601.16

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AMA Style

Hasyizan Mohamad Hassan, Nurul Ashikin Hasbullah, Saedah Ali, Ruwaida Isa. Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment. Int J Anesth Clin Med. 2018;6(1):33-39. doi: 10.11648/j.ja.20180601.16

Copy | Download

@article{10.11648/j.ja.20180601.16,
  author = {Hasyizan Mohamad Hassan and Nurul Ashikin Hasbullah and Saedah Ali and Ruwaida Isa},
  title = {Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment},
  journal = {International Journal of Anesthesia and Clinical Medicine},
  volume = {6},
  number = {1},
  pages = {33-39},
  doi = {10.11648/j.ja.20180601.16},
  url = {https://doi.org/10.11648/j.ja.20180601.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ja.20180601.16},
  abstract = {The ideal intraoperative intravenous fluid in paediatric anaesthesia and surgery is still debatable. This is essential to overcome physiological changes to maintain safety and wellbeing of the patient. A new isotonic “balanced solution” (Sterofundin ® ISO) has been introduced to replace existing intraoperative fluid of choice (Ringer’s Lactate). The study aimed to observe any changes in electrolytes and acid base after infusion of each study solutions and to evaluate any post infusion electrolytes and acid base differences between both study solutions. The double blinded randomized control trial involved 141 paediatric patients who were subjected to minor surgical procedure of less than 3 hours were randomized into Ringer’s Lactate or Sterofundin ® ISO group. The electrolytes and acid base parameters were assessed at pre-infusion and post-infusion time. There were significant difference in glucose, potassium (K+) and chloride (Cl-) level between pre-infusion and post-infusion values with those given Ringer’s Lactate. There were also significant different in pH, base excess, glucose, Calcium (Ca2+), Chloride (Cl) and lactate level between pre-infusion and post-infusion values with Sterofundin ® ISO. When comparing the mean difference (pre-infusion and post-infusion) between Ringer’s Lactate and Sterofundin ® ISO, calcium (Ca2+) is the only electrtolyte which found to be significant (P=0.015) with the values of (Means±SD 0.005±0.07) mmol/L and (Means±SD 0.02±0.06) mmol/L respectively. Both study solutions showed variable effects of electrolytes and acid base parameters and no fluid was found to be superior in paediatric surgical patients underwent minor surgery of less than three hours.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Ringer’S Lactate Versus Sterofundin ® Iso in Paediatric Surgical Patients: The Acid Base and Electrolytes Assessment
AU  - Hasyizan Mohamad Hassan
AU  - Nurul Ashikin Hasbullah
AU  - Saedah Ali
AU  - Ruwaida Isa
Y1  - 2018/07/04
PY  - 2018
N1  - https://doi.org/10.11648/j.ja.20180601.16
DO  - 10.11648/j.ja.20180601.16
T2  - International Journal of Anesthesia and Clinical Medicine
JF  - International Journal of Anesthesia and Clinical Medicine
JO  - International Journal of Anesthesia and Clinical Medicine
SP  - 33
EP  - 39
PB  - Science Publishing Group
SN  - 2997-2698
UR  - https://doi.org/10.11648/j.ja.20180601.16
AB  - The ideal intraoperative intravenous fluid in paediatric anaesthesia and surgery is still debatable. This is essential to overcome physiological changes to maintain safety and wellbeing of the patient. A new isotonic “balanced solution” (Sterofundin ® ISO) has been introduced to replace existing intraoperative fluid of choice (Ringer’s Lactate). The study aimed to observe any changes in electrolytes and acid base after infusion of each study solutions and to evaluate any post infusion electrolytes and acid base differences between both study solutions. The double blinded randomized control trial involved 141 paediatric patients who were subjected to minor surgical procedure of less than 3 hours were randomized into Ringer’s Lactate or Sterofundin ® ISO group. The electrolytes and acid base parameters were assessed at pre-infusion and post-infusion time. There were significant difference in glucose, potassium (K+) and chloride (Cl-) level between pre-infusion and post-infusion values with those given Ringer’s Lactate. There were also significant different in pH, base excess, glucose, Calcium (Ca2+), Chloride (Cl) and lactate level between pre-infusion and post-infusion values with Sterofundin ® ISO. When comparing the mean difference (pre-infusion and post-infusion) between Ringer’s Lactate and Sterofundin ® ISO, calcium (Ca2+) is the only electrtolyte which found to be significant (P=0.015) with the values of (Means±SD 0.005±0.07) mmol/L and (Means±SD 0.02±0.06) mmol/L respectively. Both study solutions showed variable effects of electrolytes and acid base parameters and no fluid was found to be superior in paediatric surgical patients underwent minor surgery of less than three hours.
VL  - 6
IS  - 1
ER  -

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