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Comparison of Sedative Effect of Fentanil and Remifentanil during Phacoemulsification with Local Anesthesia

Received: 21 July 2014     Accepted: 9 August 2014     Published: 30 August 2014
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Abstract

Nowadays, Phacoemulsification surgery is mostly carried out under local anesthesia. In this type of anesthesia the patient needs to be sedated. Because of painful intracameral injection, an Intravenus (IV) analgesia is also required using bolus dose of Fentanil or Remifentanil. Our main purpose was the comparison of the sedative effects of 2 models of Intravenous local analgesia during Phacoemulsification in cataractus patients. Moreover , to investigate the patient, surgeon satisfaction and complication rate in two groups. Material and methods: This Clinical Trial study was carried out on 64 patients with cataract who underwent phacoemulsification surgery in Baqiyatallah hospital in second half of year 2013. Patients with American Society of Anesthesiologists (ASA) Physical Status classification system ; ASA class I & II were chosen and randomly divided into two groups. The level of sedation was assessed using the Ramsay sedation(RS) scale. Moreover , along with sedative effect, patient, surgeon satisfaction ,Vital signs, rate of pain and complication rate were recorded and compared in two groups. Results: Thirty six patients were in Fentanil group with mean age of 64.71± 8.21 years and 28 in Remifentanil group with mean age of 65.2 ± 12.43. RS in Fentanil group was significantly higher than Remifentanil group (2.02±1.08 versus 1.42±1.19, p<.05). Rate of satisfaction of patients and surgeons was significantly higher in Fentanil group in comparison with Remifentanil group (p<.05). Side effects in Fentanil group was also significantly less than Remifentanil (p<.05). There was no significant difference in vital signs of patients in two groups neither before surgery nor after that. Conclusion: Results of this study show that, Fentanil has fewer side effects, more sedation effect and more patient and surgeon satisfaction in comparison with Remifentanil. The administration of fentanil appears to be a better choice as an analgesic with local anesthesia in cataract surgery

Published in Journal of Anesthesiology (Volume 2, Issue 3)
DOI 10.11648/j.ja.20140203.11
Page(s) 22-26
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Fentanil, Remifentanil, Cataract, Phacoemulsification, Sedation, Local Anesthesia

References
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[4] Ryu JH1, So YM, Hwang JW, Do SH.Optimal target concentration of remifentanil during cataract surgery with monitored anesthesia care. J Clin Anesth. 2010 Nov;22(7):533-7
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Cite This Article
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    Aliagha Alishiri, Mohammadjavad Foruzanmehr, Seyed Aliasghar Mosavi, Abaszadeh Mehrdad. (2014). Comparison of Sedative Effect of Fentanil and Remifentanil during Phacoemulsification with Local Anesthesia. International Journal of Anesthesia and Clinical Medicine, 2(3), 22-26. https://doi.org/10.11648/j.ja.20140203.11

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    Aliagha Alishiri; Mohammadjavad Foruzanmehr; Seyed Aliasghar Mosavi; Abaszadeh Mehrdad. Comparison of Sedative Effect of Fentanil and Remifentanil during Phacoemulsification with Local Anesthesia. Int. J. Anesth. Clin. Med. 2014, 2(3), 22-26. doi: 10.11648/j.ja.20140203.11

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    AMA Style

    Aliagha Alishiri, Mohammadjavad Foruzanmehr, Seyed Aliasghar Mosavi, Abaszadeh Mehrdad. Comparison of Sedative Effect of Fentanil and Remifentanil during Phacoemulsification with Local Anesthesia. Int J Anesth Clin Med. 2014;2(3):22-26. doi: 10.11648/j.ja.20140203.11

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  • @article{10.11648/j.ja.20140203.11,
      author = {Aliagha Alishiri and Mohammadjavad Foruzanmehr and Seyed Aliasghar Mosavi and Abaszadeh Mehrdad},
      title = {Comparison of Sedative Effect of Fentanil and Remifentanil during Phacoemulsification with Local Anesthesia},
      journal = {International Journal of Anesthesia and Clinical Medicine},
      volume = {2},
      number = {3},
      pages = {22-26},
      doi = {10.11648/j.ja.20140203.11},
      url = {https://doi.org/10.11648/j.ja.20140203.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ja.20140203.11},
      abstract = {Nowadays, Phacoemulsification surgery is mostly carried out under local anesthesia. In this type of  anesthesia the patient needs to be sedated. Because  of   painful intracameral injection, an Intravenus (IV) analgesia is also required using  bolus dose of Fentanil or  Remifentanil. Our main purpose was  the comparison of  the  sedative effects of 2 models of Intravenous  local analgesia during  Phacoemulsification in cataractus patients. Moreover , to investigate the patient, surgeon satisfaction and complication rate in two groups. Material and methods: This Clinical Trial study was carried out on 64 patients with cataract who underwent phacoemulsification surgery in Baqiyatallah hospital in second half of year 2013. Patients with American Society of Anesthesiologists (ASA) Physical Status classification system ; ASA class I & II were chosen and randomly divided into two groups. The level of sedation was assessed using the Ramsay sedation(RS) scale. Moreover , along with sedative effect, patient, surgeon satisfaction ,Vital signs, rate  of pain and complication rate were recorded  and compared in two groups. Results: Thirty six patients were in Fentanil group with  mean age of  64.71± 8.21 years and 28 in Remifentanil group with  mean age of  65.2 ± 12.43. RS in Fentanil group was significantly higher than Remifentanil group (2.02±1.08 versus  1.42±1.19, p<.05). Rate of satisfaction of patients and surgeons was significantly higher in Fentanil group in comparison with Remifentanil group (p<.05). Side effects in Fentanil group was also significantly less than Remifentanil (p<.05). There was no significant difference in vital signs of patients in two groups neither before surgery nor after that. Conclusion: Results of this study show that, Fentanil has fewer side effects, more sedation effect and more patient and surgeon satisfaction in comparison with Remifentanil. The administration of fentanil appears to be a better choice as an analgesic with local anesthesia in cataract surgery},
     year = {2014}
    }
    

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  • TY  - JOUR
    T1  - Comparison of Sedative Effect of Fentanil and Remifentanil during Phacoemulsification with Local Anesthesia
    AU  - Aliagha Alishiri
    AU  - Mohammadjavad Foruzanmehr
    AU  - Seyed Aliasghar Mosavi
    AU  - Abaszadeh Mehrdad
    Y1  - 2014/08/30
    PY  - 2014
    N1  - https://doi.org/10.11648/j.ja.20140203.11
    DO  - 10.11648/j.ja.20140203.11
    T2  - International Journal of Anesthesia and Clinical Medicine
    JF  - International Journal of Anesthesia and Clinical Medicine
    JO  - International Journal of Anesthesia and Clinical Medicine
    SP  - 22
    EP  - 26
    PB  - Science Publishing Group
    SN  - 2997-2698
    UR  - https://doi.org/10.11648/j.ja.20140203.11
    AB  - Nowadays, Phacoemulsification surgery is mostly carried out under local anesthesia. In this type of  anesthesia the patient needs to be sedated. Because  of   painful intracameral injection, an Intravenus (IV) analgesia is also required using  bolus dose of Fentanil or  Remifentanil. Our main purpose was  the comparison of  the  sedative effects of 2 models of Intravenous  local analgesia during  Phacoemulsification in cataractus patients. Moreover , to investigate the patient, surgeon satisfaction and complication rate in two groups. Material and methods: This Clinical Trial study was carried out on 64 patients with cataract who underwent phacoemulsification surgery in Baqiyatallah hospital in second half of year 2013. Patients with American Society of Anesthesiologists (ASA) Physical Status classification system ; ASA class I & II were chosen and randomly divided into two groups. The level of sedation was assessed using the Ramsay sedation(RS) scale. Moreover , along with sedative effect, patient, surgeon satisfaction ,Vital signs, rate  of pain and complication rate were recorded  and compared in two groups. Results: Thirty six patients were in Fentanil group with  mean age of  64.71± 8.21 years and 28 in Remifentanil group with  mean age of  65.2 ± 12.43. RS in Fentanil group was significantly higher than Remifentanil group (2.02±1.08 versus  1.42±1.19, p<.05). Rate of satisfaction of patients and surgeons was significantly higher in Fentanil group in comparison with Remifentanil group (p<.05). Side effects in Fentanil group was also significantly less than Remifentanil (p<.05). There was no significant difference in vital signs of patients in two groups neither before surgery nor after that. Conclusion: Results of this study show that, Fentanil has fewer side effects, more sedation effect and more patient and surgeon satisfaction in comparison with Remifentanil. The administration of fentanil appears to be a better choice as an analgesic with local anesthesia in cataract surgery
    VL  - 2
    IS  - 3
    ER  - 

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Author Information
  • Department of Ophthalmology, Baqiyatallah University of Medical Sciences, Tehran, Iran

  • Department of Ophthalmology, Baqiyatallah University of Medical Sciences, Tehran, Iran

  • Department of Ophthalmology, Bina Eye Hospital Research center, Tehran, Iran

  • Department of Ophthalmology, Baqiyatallah University of Medical Sciences, Bina Eye Hospital Research Center, Tehran, Iran

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