Research Article | | Peer-Reviewed

Chinese Expert Consensus on Celiac Plexus Block and Neurolysis for Upper Abdominal Pain (2026)

Received: 13 January 2026     Accepted: 2 February 2026     Published: 20 February 2026
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Abstract

Celiac plexus block and neurolysis (CPB/N) is an effective interventional technique for treating chronic upper abdominal pain. Currently, there are various CPB/N techniques, and there is an urgent need to develop an expert consensus to enable clinicians to correctly implement the CPB/N technique, improve efficacy, and reduce complications. A total of 20 medical experts were invited to participate in the writing of this expert consensus, including pain physicians, interventional radiologists, gastroenterologists/endoscopists, and anatomy professors. All experts are from Class A tertiary hospitals affiliated of medical universities in parts of China. Except for the anatomy professors, all experts are engaged in the clinical practice of CPB/N surgery and are familiar with indications, surgical procedures, and complication management. Chinese and English literatures related to CPB/N from January 2008 to October 2025 were retrieved to evaluate the recommendation levels. Each expert made multiple revisions to the initial draft of the expert consensus and voted on the classification levels with significant disagreements. This expert consensus reviews the anatomical characteristics of the celiac plexus, summarizes the indications and contraindications for the clinical implementation of CPB/N, describes in detail the technical methods of CPB/N via different approaches, expounds on the drugs and dosages for CPB and CPN, and depicts the clinical manifestations, management, and prevention of complications. Based on the current domestic practice of CPB/N and literature reports, the recommended grades for CPB/N are proposed. We recommend the posterior retrocrural/antecrural approach under CT guidance and EUS-guided CPB/N technique due to their high success rate and low risk. We do not recommend the approach with potential iatrogenic risks, such as transarterial puncture. The incidence of CPB/N complications is very low, and some complications are temporary. Performing CPB/N under imaging guidance can prevent the occurrence of serious complications such as nerve injury and bleeding.

Published in International Journal of Pain Research (Volume 2, Issue 1)
DOI 10.11648/j.ijpr.20260201.12
Page(s) 15-30
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2026. Published by Science Publishing Group

Keywords

Celiac Plexus, Splanchnic Nerve, Nerve Block, Neurolysis, Alcohol, Cancer Pain, Expert Consensus

References
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Cite This Article
  • APA Style

    Wang, X., Zhou, H., Xu, W., Liu, X., Ni, J., et al. (2026). Chinese Expert Consensus on Celiac Plexus Block and Neurolysis for Upper Abdominal Pain (2026). International Journal of Pain Research, 2(1), 15-30. https://doi.org/10.11648/j.ijpr.20260201.12

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    ACS Style

    Wang, X.; Zhou, H.; Xu, W.; Liu, X.; Ni, J., et al. Chinese Expert Consensus on Celiac Plexus Block and Neurolysis for Upper Abdominal Pain (2026). . 2026, 2(1), 15-30. doi: 10.11648/j.ijpr.20260201.12

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    AMA Style

    Wang X, Zhou H, Xu W, Liu X, Ni J, et al. Chinese Expert Consensus on Celiac Plexus Block and Neurolysis for Upper Abdominal Pain (2026). . 2026;2(1):15-30. doi: 10.11648/j.ijpr.20260201.12

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  • @article{10.11648/j.ijpr.20260201.12,
      author = {Xiaowen Wang and Huacheng Zhou and Wenjian Xu and Xiaohui Liu and Jiaxiang Ni and Guanglun Xie and Changsheng Ma and Senlin Hou and Zhaoxia Xue and Dong Yang and Xiaoqiu Yang and Tao Song and Tao Sun and Lingjie Xia and Ruilin He and Ke Ma and Lijuan Lu and Yongjin He and Li Wan and Guangzhao Liu},
      title = {Chinese Expert Consensus on Celiac Plexus Block and Neurolysis for Upper Abdominal Pain (2026)},
      journal = {International Journal of Pain Research},
      volume = {2},
      number = {1},
      pages = {15-30},
      doi = {10.11648/j.ijpr.20260201.12},
      url = {https://doi.org/10.11648/j.ijpr.20260201.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpr.20260201.12},
      abstract = {Celiac plexus block and neurolysis (CPB/N) is an effective interventional technique for treating chronic upper abdominal pain. Currently, there are various CPB/N techniques, and there is an urgent need to develop an expert consensus to enable clinicians to correctly implement the CPB/N technique, improve efficacy, and reduce complications. A total of 20 medical experts were invited to participate in the writing of this expert consensus, including pain physicians, interventional radiologists, gastroenterologists/endoscopists, and anatomy professors. All experts are from Class A tertiary hospitals affiliated of medical universities in parts of China. Except for the anatomy professors, all experts are engaged in the clinical practice of CPB/N surgery and are familiar with indications, surgical procedures, and complication management. Chinese and English literatures related to CPB/N from January 2008 to October 2025 were retrieved to evaluate the recommendation levels. Each expert made multiple revisions to the initial draft of the expert consensus and voted on the classification levels with significant disagreements. This expert consensus reviews the anatomical characteristics of the celiac plexus, summarizes the indications and contraindications for the clinical implementation of CPB/N, describes in detail the technical methods of CPB/N via different approaches, expounds on the drugs and dosages for CPB and CPN, and depicts the clinical manifestations, management, and prevention of complications. Based on the current domestic practice of CPB/N and literature reports, the recommended grades for CPB/N are proposed. We recommend the posterior retrocrural/antecrural approach under CT guidance and EUS-guided CPB/N technique due to their high success rate and low risk. We do not recommend the approach with potential iatrogenic risks, such as transarterial puncture. The incidence of CPB/N complications is very low, and some complications are temporary. Performing CPB/N under imaging guidance can prevent the occurrence of serious complications such as nerve injury and bleeding.},
     year = {2026}
    }
    

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  • TY  - JOUR
    T1  - Chinese Expert Consensus on Celiac Plexus Block and Neurolysis for Upper Abdominal Pain (2026)
    AU  - Xiaowen Wang
    AU  - Huacheng Zhou
    AU  - Wenjian Xu
    AU  - Xiaohui Liu
    AU  - Jiaxiang Ni
    AU  - Guanglun Xie
    AU  - Changsheng Ma
    AU  - Senlin Hou
    AU  - Zhaoxia Xue
    AU  - Dong Yang
    AU  - Xiaoqiu Yang
    AU  - Tao Song
    AU  - Tao Sun
    AU  - Lingjie Xia
    AU  - Ruilin He
    AU  - Ke Ma
    AU  - Lijuan Lu
    AU  - Yongjin He
    AU  - Li Wan
    AU  - Guangzhao Liu
    Y1  - 2026/02/20
    PY  - 2026
    N1  - https://doi.org/10.11648/j.ijpr.20260201.12
    DO  - 10.11648/j.ijpr.20260201.12
    T2  - International Journal of Pain Research
    JF  - International Journal of Pain Research
    JO  - International Journal of Pain Research
    SP  - 15
    EP  - 30
    PB  - Science Publishing Group
    SN  - 3070-1562
    UR  - https://doi.org/10.11648/j.ijpr.20260201.12
    AB  - Celiac plexus block and neurolysis (CPB/N) is an effective interventional technique for treating chronic upper abdominal pain. Currently, there are various CPB/N techniques, and there is an urgent need to develop an expert consensus to enable clinicians to correctly implement the CPB/N technique, improve efficacy, and reduce complications. A total of 20 medical experts were invited to participate in the writing of this expert consensus, including pain physicians, interventional radiologists, gastroenterologists/endoscopists, and anatomy professors. All experts are from Class A tertiary hospitals affiliated of medical universities in parts of China. Except for the anatomy professors, all experts are engaged in the clinical practice of CPB/N surgery and are familiar with indications, surgical procedures, and complication management. Chinese and English literatures related to CPB/N from January 2008 to October 2025 were retrieved to evaluate the recommendation levels. Each expert made multiple revisions to the initial draft of the expert consensus and voted on the classification levels with significant disagreements. This expert consensus reviews the anatomical characteristics of the celiac plexus, summarizes the indications and contraindications for the clinical implementation of CPB/N, describes in detail the technical methods of CPB/N via different approaches, expounds on the drugs and dosages for CPB and CPN, and depicts the clinical manifestations, management, and prevention of complications. Based on the current domestic practice of CPB/N and literature reports, the recommended grades for CPB/N are proposed. We recommend the posterior retrocrural/antecrural approach under CT guidance and EUS-guided CPB/N technique due to their high success rate and low risk. We do not recommend the approach with potential iatrogenic risks, such as transarterial puncture. The incidence of CPB/N complications is very low, and some complications are temporary. Performing CPB/N under imaging guidance can prevent the occurrence of serious complications such as nerve injury and bleeding.
    VL  - 2
    IS  - 1
    ER  - 

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Author Information
  • Department of Painology, The Second Hospital of Hebei Medical University, Shijiazhuang, China

  • Department of Painology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China

  • Department of Radiology, Affiliated Hospital of Qingdao University, Qingdao, China

  • Department of Painology, The Second Hospital of Hebei Medical University, Shijiazhuang, China

  • Department of Painology, Xuanwu Hospital of Capital Medical University, Beijing, China

  • Department of Pain & Rehabilitation and Palliative Medicine, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China

  • Department of Human Anatomy, Hebei Medical University, Shijiazhuang, China

  • Department of Bilio Pancreatic Endoscopic Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, China

  • Department of Painology, The First Hospital of Shanxi Medical University, Taiyuan, China

  • Department of Pain Medicine, Union Hospital of Huazhong Science and Technology University, Wuhan, China

  • Department of Painology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

  • Department of Painology, The First Hospital of China Medical University, Shenyang, China

  • Department of Pain Medicine, Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China

  • Department of Pain Medicine, Henan Provincial People's Hospital, Zhengzhou, China

  • Department of Painology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China

  • Department of Pain Medicine, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

  • Department of Painology, Nanjing Gulou Hospital, Nanjing, China

  • Department of Painology, Tianjin First Central Hospital, Tianjin, China

  • Department of Painology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China

  • Department of Painology, The Second Hospital of Hebei Medical University, Shijiazhuang, China

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