Background: Scleritis is a rare inflammation of the outer coat of the eye, which is often characterized by pain and redness and may be associated with visual loss and blindness. Posterior scleritis may lead to the formation of a choroidal mass which is often confused with choroidal tumors. A delayed and an inaccurate diagnosis may lead to devastating outcomes, that including unnecessary enucleation. Therefore, a prudent clinical judgement is necessary. Objective: To report clinical characteristics of an outstanding posterior scleritis which required a multidisciplinary collaboration for its management. Method: A young man presented with redness and diminished vision in his right eye for 5 days. A detailed ophthalmological examination was completed, which suggested a final diagnosis of posterior nodular scleritis that was presumed to occur secondary to anti-neutrophil cytoplasmic antibodies-associated granulomatosis with polyangiitis. A multimodal imaging workup suggested posterior nodular scleritis and laboratory investigation confirmed positive antineutrophil cytoplasmic antibodies (C-ANCAs). All other infectious and immunological tests came negative. The patient was subsequently treated with systemic steroids and immunomodulatory therapy, with an excellent visual recovery. Best-corrected visual acuity improved from 20/200 at presentation to 20/25 at eight months after the therapy, and there was no evidence of disease recurrence. Conclusion: Nodular posterior scleritis is an important but benign disease that may mimic an intraocular tumor. Multimodal imaging studies and detailed laboratory investigations are essential for its correct diagnosis and appropriate management.
Published in | International Journal of Ophthalmology & Visual Science (Volume 7, Issue 1) |
DOI | 10.11648/j.ijovs.20220701.11 |
Page(s) | 1-5 |
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2022. Published by Science Publishing Group |
Nodular Posterior Scleritis, Granulomatosis with Polyangiitis, C-ANCA, Ultrasonography, Intraocular Mass
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APA Style
Armando Bautista-Barba, Erick Andres Quiroz-Gonzalez, Miguel Angel Quiroz-Reyes, Jhoana Sanchez-Ruiz, Rafael Valdez-Sosa, et al. (2022). Nodular Posterior Scleritis: A Clinical Case Report. International Journal of Ophthalmology & Visual Science, 7(1), 1-5. https://doi.org/10.11648/j.ijovs.20220701.11
ACS Style
Armando Bautista-Barba; Erick Andres Quiroz-Gonzalez; Miguel Angel Quiroz-Reyes; Jhoana Sanchez-Ruiz; Rafael Valdez-Sosa, et al. Nodular Posterior Scleritis: A Clinical Case Report. Int. J. Ophthalmol. Vis. Sci. 2022, 7(1), 1-5. doi: 10.11648/j.ijovs.20220701.11
AMA Style
Armando Bautista-Barba, Erick Andres Quiroz-Gonzalez, Miguel Angel Quiroz-Reyes, Jhoana Sanchez-Ruiz, Rafael Valdez-Sosa, et al. Nodular Posterior Scleritis: A Clinical Case Report. Int J Ophthalmol Vis Sci. 2022;7(1):1-5. doi: 10.11648/j.ijovs.20220701.11
@article{10.11648/j.ijovs.20220701.11, author = {Armando Bautista-Barba and Erick Andres Quiroz-Gonzalez and Miguel Angel Quiroz-Reyes and Jhoana Sanchez-Ruiz and Rafael Valdez-Sosa and Gerardo Ledesma-Gil and Miguel Pedroza-Seres and Federico Graue-Wiechers}, title = {Nodular Posterior Scleritis: A Clinical Case Report}, journal = {International Journal of Ophthalmology & Visual Science}, volume = {7}, number = {1}, pages = {1-5}, doi = {10.11648/j.ijovs.20220701.11}, url = {https://doi.org/10.11648/j.ijovs.20220701.11}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20220701.11}, abstract = {Background: Scleritis is a rare inflammation of the outer coat of the eye, which is often characterized by pain and redness and may be associated with visual loss and blindness. Posterior scleritis may lead to the formation of a choroidal mass which is often confused with choroidal tumors. A delayed and an inaccurate diagnosis may lead to devastating outcomes, that including unnecessary enucleation. Therefore, a prudent clinical judgement is necessary. Objective: To report clinical characteristics of an outstanding posterior scleritis which required a multidisciplinary collaboration for its management. Method: A young man presented with redness and diminished vision in his right eye for 5 days. A detailed ophthalmological examination was completed, which suggested a final diagnosis of posterior nodular scleritis that was presumed to occur secondary to anti-neutrophil cytoplasmic antibodies-associated granulomatosis with polyangiitis. A multimodal imaging workup suggested posterior nodular scleritis and laboratory investigation confirmed positive antineutrophil cytoplasmic antibodies (C-ANCAs). All other infectious and immunological tests came negative. The patient was subsequently treated with systemic steroids and immunomodulatory therapy, with an excellent visual recovery. Best-corrected visual acuity improved from 20/200 at presentation to 20/25 at eight months after the therapy, and there was no evidence of disease recurrence. Conclusion: Nodular posterior scleritis is an important but benign disease that may mimic an intraocular tumor. Multimodal imaging studies and detailed laboratory investigations are essential for its correct diagnosis and appropriate management.}, year = {2022} }
TY - JOUR T1 - Nodular Posterior Scleritis: A Clinical Case Report AU - Armando Bautista-Barba AU - Erick Andres Quiroz-Gonzalez AU - Miguel Angel Quiroz-Reyes AU - Jhoana Sanchez-Ruiz AU - Rafael Valdez-Sosa AU - Gerardo Ledesma-Gil AU - Miguel Pedroza-Seres AU - Federico Graue-Wiechers Y1 - 2022/01/12 PY - 2022 N1 - https://doi.org/10.11648/j.ijovs.20220701.11 DO - 10.11648/j.ijovs.20220701.11 T2 - International Journal of Ophthalmology & Visual Science JF - International Journal of Ophthalmology & Visual Science JO - International Journal of Ophthalmology & Visual Science SP - 1 EP - 5 PB - Science Publishing Group SN - 2637-3858 UR - https://doi.org/10.11648/j.ijovs.20220701.11 AB - Background: Scleritis is a rare inflammation of the outer coat of the eye, which is often characterized by pain and redness and may be associated with visual loss and blindness. Posterior scleritis may lead to the formation of a choroidal mass which is often confused with choroidal tumors. A delayed and an inaccurate diagnosis may lead to devastating outcomes, that including unnecessary enucleation. Therefore, a prudent clinical judgement is necessary. Objective: To report clinical characteristics of an outstanding posterior scleritis which required a multidisciplinary collaboration for its management. Method: A young man presented with redness and diminished vision in his right eye for 5 days. A detailed ophthalmological examination was completed, which suggested a final diagnosis of posterior nodular scleritis that was presumed to occur secondary to anti-neutrophil cytoplasmic antibodies-associated granulomatosis with polyangiitis. A multimodal imaging workup suggested posterior nodular scleritis and laboratory investigation confirmed positive antineutrophil cytoplasmic antibodies (C-ANCAs). All other infectious and immunological tests came negative. The patient was subsequently treated with systemic steroids and immunomodulatory therapy, with an excellent visual recovery. Best-corrected visual acuity improved from 20/200 at presentation to 20/25 at eight months after the therapy, and there was no evidence of disease recurrence. Conclusion: Nodular posterior scleritis is an important but benign disease that may mimic an intraocular tumor. Multimodal imaging studies and detailed laboratory investigations are essential for its correct diagnosis and appropriate management. VL - 7 IS - 1 ER -