Perfusion Findings in Surgically Resolved Myopic Foveoretinal Detachment

Miguel Angel Quiroz-Reyes; Erick Andres Quiroz-Gonzalez; Jorge Morales-Navarro; Boris Moreno-Andrade; Alejandra Nieto-Jordan; Federico Graue-Wiechers

doi:doi:10.11648/j.ijovs.20210604.21

Perfusion Findings in Surgically Resolved Myopic Foveoretinal Detachment

Miguel Angel Quiroz-Reyes, Erick Andres Quiroz-Gonzalez, Jorge Morales-Navarro, Boris Moreno-Andrade, Alejandra Nieto-Jordan, Federico Graue-Wiechers

Published in International Journal of Ophthalmology & Visual Science (Volume 6, Issue 4)

Received: 16 November 2021 Accepted: 3 December 2021 Published: 10 December 2021

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Purpose: Published data on long-term macular perfusional findings and qualitative vessel density (VD) evaluation of myopic foveoretinal detachment (FRD) are limited. This study aimed to evaluate the OCT angiographic findings after uncomplicated successful macular surgery in fully surgically resolved myopic FRD. Methods: Between October 2016 and April 2020, an interventional, single-surgeon case series was conducted involving three structurally fully resolved highly myopic eyes with FRD. Long-term postoperative spectral domain-optical coherence tomography (SD-OCT) and functional and follow-up perfusion evaluations with SD-OCT and OCT angiography were performed. The main outcome was long-term structural and macular perfusion status after successful surgical resolution of myopic FRD. Results: The mean evolution time of myopic FRD was 7.33 ± 3.68 months. The mean follow-up time was 59.3 ±12.20 months and the mean time for resolution of myopic FRD was 4.6 ± 1.98 weeks. Using a paired-samples permutation test, we observed that surgery was associated with a significant improvement in visual acuity: best-corrected visual acuity decreased from logMAR 0.88 ± 0.15 pre-surgery to 0.36 ± 0.20 post-surgery (P<0.0001). Qualitative VD evaluation patterns were lower in eyes post-surgery than in normal emmetropic and highly myopic eyes. The observed foveal avascular zone (FAZ) area was large and irregular in fully resolved myopic FRD. A lack of SD-OCT structural postoperative findings and better qualitative perfusion findings were associated with better final visual results. Conclusion: The results revealed postoperative microstructural abnormalities on SD-OCT with VD qualitative deficiencies in the superficial vascular complex of the macula with FAZ abnormalities in the three eyes.

Published in	International Journal of Ophthalmology & Visual Science (Volume 6, Issue 4)
DOI	10.11648/j.ijovs.20210604.21
Page(s)	252-262
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Deep Vascular Plexus, Foveoretinal Detachment, High Myopia, Myopic Foveoschisis, Foveal Avascular Zone, Perfusion Macular Status, Vessel Density, Superficial Vascular Plexus

References

[1]	Morgan IG, Ohno-Matsui K, Saw SM (2012) Myopia. Lancet, 379 (9827), 1739-1748.
[2]	Pathological myopia is the fifth-leading cause of low vision or blindness in Japan and the second-leading cause among people aged over 40 years in China.
[3]	Iwase A, Araie M, Tomidokoro A, Yamamoto T, Shimizu H, Kitazawa Y (2006) Prevalence and causes of low vision and blindness in a Japanese adult population: the Tajimi Study. Ophthalmology, 113 (8), 1354-1362. https://doi.org/10.1016/j.ophtha.2006.04.022.
[4]	Flitcroft DI, He M, Jonas JB, Jong M, Naidoo K, Ohno-Matsui K (2019) IMI Defining and classifying myopia: A proposed set of standards for clinical and epidemiologic studies. Investigative Ophthalmology & Visual Science, 60 (3), M20-M30. doi: 10.1167/iovs.18-25957.
[5]	Ruiz-Medrano J, Flores-Moreno I, Ohno-Matsui K, Cheung CM, Silva R, Ruiz-Moreno JM (2020) Validation of the recently developed ATN classification and grading system for myopic maculopathy. Retina, 40 (13), 2113–2118.
[6]	Ohno-Matsui K, Kawasaki R, Jonas JB, Cheung CM, Saw SM, Verhoeven VJ, et al (2015) International photographic classification and grading system for myopic maculopathy Meta-analysis for pathologic myopia (META-PM) study group. American Journal of Ophthalmology. 159 (5), 877-883.e7. https://doi.org/10.1016/j.ajo.2015.01.022.
[7]	Vitale S, Sperduto RD, Ferris FL 3rd (2009) Increased prevalence of myopia in the United States between 1971–1972 and 1999–2004. Archives of Ophthalmology. 127 (12), 1632–1639. https://doi.org/10.1001/archophthalmol.2009.303.
[8]	Wang SW, Hsia Y, Huang CJ, Hung KC, Chen MS, Ho TC, et al (2021) Biomarkers in the pathogenesis of epiretinal membrane and myopic traction maculopathy: effects of internal limiting membrane incompliance and posterior staphyloma. Photodiagnosis and Photodynamic Therapy, 33, 102208. https://doi.org/10.1016/j.pdpdt.2021.102208.
[9]	Shimada N, Tanaka Y, Tokoro T, Ohno-Matsui K (2013) Natural course of myopic traction maculopathy and factors associated with progression or resolution. American Journal of Ophthalmology, 156 (5), 948–957.e1. https://doi.org/10.1016/j.ajo.2013.06.031.
[10]	Shimada N, Ohno-Matsui K, Baba T, Futagami S, Tokoro T, Mochizuki M (2006) Natural course of macular retinoschisis in highly myopic eyes without macular hole or retinal detachment. American Journal of Ophthalmology, 142 (3), 497–500. https://doi.org/10.1016/j.ajo.2006.03.048.
[11]	Ikuno Y, Tano Y (2003) Early macular holes with retinoschisis in highly myopic eyes. American Journal of Ophthalmology, 136 (4), 741–744. https://doi.org/10.1016/s0002-9394(03)00319-2.
[12]	Rada JA, Shelton S, Norton TT (2006) The sclera and myopia. Experimental Eye Research, 82 (2), 185-200. https://doi.org/10.1016/j.exer.2005.08.009.
[13]	Panozzo G, Mercanti A (2004) Optical coherence tomography findings in myopic traction maculopathy. Archives of Ophthalmology, 122 (10), 1455-1460. https://doi.org/10.1001/archopht.122.10.1455.
[14]	Margolis R, Spaide RF (2009) A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes. American Journal of Ophthalmology, 147 (5), 811-815. https://doi.org/10.1016/j.ajo.2008.12.008.
[15]	Panozzo G, Mercanti A (2007) Vitrectomy for myopic traction maculopathy. Archives of Ophthalmology, 125 (6), 767-772. https://doi.org/10.1001/archopht.125.6.767.
[16]	Takano M, Kishi S (1999) Foveal retinoschisis and retinal detachment in severely myopic eyes with posterior staphyloma. American Journal of Ophthalmology, 128 (4), 472-476. https://doi.org/10.1016/s0002-9394(99)00186-5.
[17]	Uchida A, Shinoda H, Koto T, Mochimaru H, Nagai N, Tsubota K, et al (2014) Vitrectomy for myopic foveoschisis with internal limiting membrane peeling and no gas tamponade. Retina, 34 (3), 455-460. https://doi.org/10.1097/IAE.0b013e3182a0e477.
[18]	Ikuno Y, Gomi F, Tano Y (2005) Potent retinal arteriolar traction as a possible cause of myopic foveoschisis. American Journal of Ophthalmology, 139, 462-467. https://doi.org/10.1016/j.ajo.2004.09.078.
[19]	Ho AC, Yannuzzi LA, Guyer DR, Slakter JS, Sorenson JA, Orlock DA (1994) Intraretinal leakage of indocyanine green dye. Ophthalmology, 101 (3), 534-541.
[20]	Hwang TS, Zhang M, Bhavsar K, Zhang X, Campbell JP, Lin P, et al (2016) Visualization of 3 distinct retinal plexuses by projection-resolved optical coherence tomography angiography in diabetic retinopathy. JAMA Ophthalmology, 134 (12), 1411-1419.
[21]	OHSU, Study shows new technology may improve management of leading causes of blindness. Portland, OR: Oregon Health & Science University; 2015.
[22]	Klufas MA, Phasukkijwatana N, Iafe NA, Prasad PS, Agarwal A, Gupta V (2017) Optical coherence tomography angiography reveals choriocapillaris flow reduction in placoid chorioretinitis. Ophthalmology Retina, 1 (1), 77–91.
[23]	Kuehlewein L, Bansal M, Lenis TL, Iafe A, Sadda SR, Bonini Filho MA (2015) Optical coherence tomography angiography of type 1 neovascularization in age-related macular degeneration. American Journal Ophthalmology, 160 (4), 739–748.e2.
[24]	Hothorn T, Hornick K, van de Wiel MA, Zeileis A (2008) Implementing a class of permutation tests: the coin package. Journal of Statistical Software, 28 (8), 1-23. https://doi.org/10.18637/jss.v028.i08.
[25]	Garren ST (2017) Permutation tests for nonparametric statistics using R. Asian Research Journal of Mathematics, 5 (2), 1-8. https://doi.org/10.9734/ARJOM/2017/34694.
[26]	Wang S-W, Hung K-C, Tsai C-Y, Chen M-S, Ho T-C (2019) Myopic traction maculopathy biomarkers on optical coherence tomography angiography—an overlooked mechanism of visual acuity correction in myopic eyes. Eye (London, Englang), 33 (8), 1305-1313.
[27]	Shimada N, Sugamoto Y, Ogawa M, Takase H, Ohno-Matsui K (2012) Fovea-sparing internal limiting membrane peeling for myopic traction maculopathy. American Journal of Ophthalmology, 154 (4), 693-701. https://doi.org/10.1016/j.ajo.2012.04.013.
[28]	Shiraki N, Wakabayashi T, Ikuno Y, Matsumura N, Sato S, Sakaguchi H, et al (2020) Fovea-sparing versus standard internal limiting membrane peeling for myopic traction maculopathy: a study of 102 consecutive cases. Ophthalmology. Retina, 4 (12), 1170–1180. https://doi.org/10.1016/j.oret.2020.05.016.
[29]	Wong QY, Dan YS, Go You DJ, Hoang QV, Wong CW (2020). A microperimetric evaluation of macular function in highly myopic eyes with myopic macular degeneration. ARVO Annual Meeting Extract. Investigative Ophthalmology & Visual Science, 61, 2683.
[30]	Al-Sheikh M, Phasukkijwatana N, Dolz-Marco R, Rahimi M, Iafe NA, Freund KB (2017) Quantitative OCT angiography of the retinal microvasculature and the choriocapillaris in myopic eyes. Investigative Ophthalmology & Visual Science, 58 (4), 2063-2069.
[31]	Gaucher D, Haouchine B, Tadayoni R, Massin P, Erginay A, Benhamou N (2007) Long-term follow-up of high myopic foveoschisis: natural course and surgical outcome. American Journal of Ophthalmology, 143 (3), 455-462. https://doi.org/10.1016/j.ajo.2006.10.053.
[32]	Sebag J (2004) Anomalous posterior vitreous detachment: a unifying concept in vitreo-retinal disease. Graefe’s Archive for Clinical and Experimental Ophthalmology, 242 (8), 690–698.
[33]	Tang J, Rivers MB, Moshfeghi AA, Flynn HW, Jr, Chan CC (2010) Pathology of macular foveoschisis associated with degenerative myopia. Journal of Ophthalmology, 2010, 175613. https://doi.org/10.1155/2010/175613; 20814547.
[34]	Park S, Lee YJ (2013) Nano-mechanical compliance of Müller cells investigated by atomic force microscopy. International Journal of Biological Sciences, 9 (7): 702-706.
[35]	Ho T-C, Yang C-M, Huang J-S, Yang C-H, Yeh P-T, Chen T-C (2014) Long-term outcome of foveolar internal limiting membrane nonpeeling for myopic traction maculopathy. Retina, 34 (9), 1833–1840.
[36]	Yu DY, Cringle SJ (2001) Oxygen distribution and consumption within the retina in vascularized and avascular retinas and in animal models of retinal disease. Progress in Retinal and Eye Research, 20 (2), 175-208.
[37]	Sakata K, Funatsu H, Harino S, Noma H, Hori S (2006) Relationship between macular microcirculation and progression of diabetic macular edema. Ophthalmology, 113 (8), 1385-1391.
[38]	Chin EK, Kim DY, Hunter AA, Pilli S, Wilson M, Zawadzki RJ, et al (2013) Staging of macular telangiectasia: power-Doppler optical coherence tomography and macular pigment optical density. Investigative Ophthalmology & Visual Science, 54 (7), 4459-4470.
[39]	Veverka KK, AbouChehade JE, Iezzi R, Jr, Pulido JS (2015) Noninvasive grading of radiation retinopathy: the use of optical coherence tomography Angiography. Retina, 35, 2400-2410.
[40]	You QS, Freeman WR, Weinreb RN, Zangwill L, Manalastas PIC, Saunnders LJ (2017) Reproducibility of vessel density measurement with optical coherence tomography angiography in eyes with and without retinopathy. Retina, 37 (8), 1475-1482. doi: 10.1097/IAE.0000000000001407.
[41]	Peng M, Wei Y, Zhang Z, Zhang T, Qui S, Fang D (2020) Increased levels of DKK1 in vitreous fluid of patients with pathological myopia and the correlation between DKK1 levels and axial length. Current Eye Research, 45 (1), 104-110.

Cite This Article

Plain Text BibTeX RIS

APA Style

Miguel Angel Quiroz-Reyes, Erick Andres Quiroz-Gonzalez, Jorge Morales-Navarro, Boris Moreno-Andrade, Alejandra Nieto-Jordan, et al. (2021). Perfusion Findings in Surgically Resolved Myopic Foveoretinal Detachment. International Journal of Ophthalmology & Visual Science, 6(4), 252-262. https://doi.org/10.11648/j.ijovs.20210604.21

Copy | Download

ACS Style

Miguel Angel Quiroz-Reyes; Erick Andres Quiroz-Gonzalez; Jorge Morales-Navarro; Boris Moreno-Andrade; Alejandra Nieto-Jordan, et al. Perfusion Findings in Surgically Resolved Myopic Foveoretinal Detachment. Int. J. Ophthalmol. Vis. Sci. 2021, 6(4), 252-262. doi: 10.11648/j.ijovs.20210604.21

Copy | Download

AMA Style

Miguel Angel Quiroz-Reyes, Erick Andres Quiroz-Gonzalez, Jorge Morales-Navarro, Boris Moreno-Andrade, Alejandra Nieto-Jordan, et al. Perfusion Findings in Surgically Resolved Myopic Foveoretinal Detachment. Int J Ophthalmol Vis Sci. 2021;6(4):252-262. doi: 10.11648/j.ijovs.20210604.21

Copy | Download

@article{10.11648/j.ijovs.20210604.21,
  author = {Miguel Angel Quiroz-Reyes and Erick Andres Quiroz-Gonzalez and Jorge Morales-Navarro and Boris Moreno-Andrade and Alejandra Nieto-Jordan and Federico Graue-Wiechers},
  title = {Perfusion Findings in Surgically Resolved Myopic Foveoretinal Detachment},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {6},
  number = {4},
  pages = {252-262},
  doi = {10.11648/j.ijovs.20210604.21},
  url = {https://doi.org/10.11648/j.ijovs.20210604.21},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210604.21},
  abstract = {Purpose: Published data on long-term macular perfusional findings and qualitative vessel density (VD) evaluation of myopic foveoretinal detachment (FRD) are limited. This study aimed to evaluate the OCT angiographic findings after uncomplicated successful macular surgery in fully surgically resolved myopic FRD. Methods: Between October 2016 and April 2020, an interventional, single-surgeon case series was conducted involving three structurally fully resolved highly myopic eyes with FRD. Long-term postoperative spectral domain-optical coherence tomography (SD-OCT) and functional and follow-up perfusion evaluations with SD-OCT and OCT angiography were performed. The main outcome was long-term structural and macular perfusion status after successful surgical resolution of myopic FRD. Results: The mean evolution time of myopic FRD was 7.33 ± 3.68 months. The mean follow-up time was 59.3 ±12.20 months and the mean time for resolution of myopic FRD was 4.6 ± 1.98 weeks. Using a paired-samples permutation test, we observed that surgery was associated with a significant improvement in visual acuity: best-corrected visual acuity decreased from logMAR 0.88 ± 0.15 pre-surgery to 0.36 ± 0.20 post-surgery (PConclusion: The results revealed postoperative microstructural abnormalities on SD-OCT with VD qualitative deficiencies in the superficial vascular complex of the macula with FAZ abnormalities in the three eyes.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Perfusion Findings in Surgically Resolved Myopic Foveoretinal Detachment
AU  - Miguel Angel Quiroz-Reyes
AU  - Erick Andres Quiroz-Gonzalez
AU  - Jorge Morales-Navarro
AU  - Boris Moreno-Andrade
AU  - Alejandra Nieto-Jordan
AU  - Federico Graue-Wiechers
Y1  - 2021/12/10
PY  - 2021
N1  - https://doi.org/10.11648/j.ijovs.20210604.21
DO  - 10.11648/j.ijovs.20210604.21
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 252
EP  - 262
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20210604.21
AB  - Purpose: Published data on long-term macular perfusional findings and qualitative vessel density (VD) evaluation of myopic foveoretinal detachment (FRD) are limited. This study aimed to evaluate the OCT angiographic findings after uncomplicated successful macular surgery in fully surgically resolved myopic FRD. Methods: Between October 2016 and April 2020, an interventional, single-surgeon case series was conducted involving three structurally fully resolved highly myopic eyes with FRD. Long-term postoperative spectral domain-optical coherence tomography (SD-OCT) and functional and follow-up perfusion evaluations with SD-OCT and OCT angiography were performed. The main outcome was long-term structural and macular perfusion status after successful surgical resolution of myopic FRD. Results: The mean evolution time of myopic FRD was 7.33 ± 3.68 months. The mean follow-up time was 59.3 ±12.20 months and the mean time for resolution of myopic FRD was 4.6 ± 1.98 weeks. Using a paired-samples permutation test, we observed that surgery was associated with a significant improvement in visual acuity: best-corrected visual acuity decreased from logMAR 0.88 ± 0.15 pre-surgery to 0.36 ± 0.20 post-surgery (PConclusion: The results revealed postoperative microstructural abnormalities on SD-OCT with VD qualitative deficiencies in the superficial vascular complex of the macula with FAZ abnormalities in the three eyes.
VL  - 6
IS  - 4
ER  -

Copy | Download

Author Information

Miguel Angel Quiroz-Reyes

Retina Service, Institute of Ophthalmology, National Autonomous University of Mexico, Mexico City, Mexico
Erick Andres Quiroz-Gonzalez

Department of Ophthalmology, Institute of Ophthalmology, National Autonomous University of Mexico, Mexico City, Mexico
Jorge Morales-Navarro

Department of Ophthalmology, Institute of Ophthalmology, National Autonomous University of Mexico, Mexico City, Mexico
Boris Moreno-Andrade

Retina Service, Institute of Ophthalmology, National Autonomous University of Mexico, Mexico City, Mexico
Alejandra Nieto-Jordan

Retina Service, Institute of Ophthalmology, National Autonomous University of Mexico, Mexico City, Mexico
Federico Graue-Wiechers

Retina Service, Institute of Ophthalmology, National Autonomous University of Mexico, Mexico City, Mexico

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Miguel Angel Quiroz-Reyes, Erick Andres Quiroz-Gonzalez, Jorge Morales-Navarro, Boris Moreno-Andrade, Alejandra Nieto-Jordan, et al. (2021). Perfusion Findings in Surgically Resolved Myopic Foveoretinal Detachment. International Journal of Ophthalmology & Visual Science, 6(4), 252-262. https://doi.org/10.11648/j.ijovs.20210604.21

Copy | Download

ACS Style

Miguel Angel Quiroz-Reyes; Erick Andres Quiroz-Gonzalez; Jorge Morales-Navarro; Boris Moreno-Andrade; Alejandra Nieto-Jordan, et al. Perfusion Findings in Surgically Resolved Myopic Foveoretinal Detachment. Int. J. Ophthalmol. Vis. Sci. 2021, 6(4), 252-262. doi: 10.11648/j.ijovs.20210604.21

Copy | Download

AMA Style

Miguel Angel Quiroz-Reyes, Erick Andres Quiroz-Gonzalez, Jorge Morales-Navarro, Boris Moreno-Andrade, Alejandra Nieto-Jordan, et al. Perfusion Findings in Surgically Resolved Myopic Foveoretinal Detachment. Int J Ophthalmol Vis Sci. 2021;6(4):252-262. doi: 10.11648/j.ijovs.20210604.21

Copy | Download

@article{10.11648/j.ijovs.20210604.21,
  author = {Miguel Angel Quiroz-Reyes and Erick Andres Quiroz-Gonzalez and Jorge Morales-Navarro and Boris Moreno-Andrade and Alejandra Nieto-Jordan and Federico Graue-Wiechers},
  title = {Perfusion Findings in Surgically Resolved Myopic Foveoretinal Detachment},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {6},
  number = {4},
  pages = {252-262},
  doi = {10.11648/j.ijovs.20210604.21},
  url = {https://doi.org/10.11648/j.ijovs.20210604.21},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210604.21},
  abstract = {Purpose: Published data on long-term macular perfusional findings and qualitative vessel density (VD) evaluation of myopic foveoretinal detachment (FRD) are limited. This study aimed to evaluate the OCT angiographic findings after uncomplicated successful macular surgery in fully surgically resolved myopic FRD. Methods: Between October 2016 and April 2020, an interventional, single-surgeon case series was conducted involving three structurally fully resolved highly myopic eyes with FRD. Long-term postoperative spectral domain-optical coherence tomography (SD-OCT) and functional and follow-up perfusion evaluations with SD-OCT and OCT angiography were performed. The main outcome was long-term structural and macular perfusion status after successful surgical resolution of myopic FRD. Results: The mean evolution time of myopic FRD was 7.33 ± 3.68 months. The mean follow-up time was 59.3 ±12.20 months and the mean time for resolution of myopic FRD was 4.6 ± 1.98 weeks. Using a paired-samples permutation test, we observed that surgery was associated with a significant improvement in visual acuity: best-corrected visual acuity decreased from logMAR 0.88 ± 0.15 pre-surgery to 0.36 ± 0.20 post-surgery (PConclusion: The results revealed postoperative microstructural abnormalities on SD-OCT with VD qualitative deficiencies in the superficial vascular complex of the macula with FAZ abnormalities in the three eyes.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Perfusion Findings in Surgically Resolved Myopic Foveoretinal Detachment
AU  - Miguel Angel Quiroz-Reyes
AU  - Erick Andres Quiroz-Gonzalez
AU  - Jorge Morales-Navarro
AU  - Boris Moreno-Andrade
AU  - Alejandra Nieto-Jordan
AU  - Federico Graue-Wiechers
Y1  - 2021/12/10
PY  - 2021
N1  - https://doi.org/10.11648/j.ijovs.20210604.21
DO  - 10.11648/j.ijovs.20210604.21
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 252
EP  - 262
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20210604.21
AB  - Purpose: Published data on long-term macular perfusional findings and qualitative vessel density (VD) evaluation of myopic foveoretinal detachment (FRD) are limited. This study aimed to evaluate the OCT angiographic findings after uncomplicated successful macular surgery in fully surgically resolved myopic FRD. Methods: Between October 2016 and April 2020, an interventional, single-surgeon case series was conducted involving three structurally fully resolved highly myopic eyes with FRD. Long-term postoperative spectral domain-optical coherence tomography (SD-OCT) and functional and follow-up perfusion evaluations with SD-OCT and OCT angiography were performed. The main outcome was long-term structural and macular perfusion status after successful surgical resolution of myopic FRD. Results: The mean evolution time of myopic FRD was 7.33 ± 3.68 months. The mean follow-up time was 59.3 ±12.20 months and the mean time for resolution of myopic FRD was 4.6 ± 1.98 weeks. Using a paired-samples permutation test, we observed that surgery was associated with a significant improvement in visual acuity: best-corrected visual acuity decreased from logMAR 0.88 ± 0.15 pre-surgery to 0.36 ± 0.20 post-surgery (PConclusion: The results revealed postoperative microstructural abnormalities on SD-OCT with VD qualitative deficiencies in the superficial vascular complex of the macula with FAZ abnormalities in the three eyes.
VL  - 6
IS  - 4
ER  -

Copy | Download