Shorten Myopic Axial Length with Repeated Low-lever Laser Light Therapy

Zhou Lei; Qiu Kaikai; William Bruce

doi:doi:10.11648/j.ijovs.20210602.22

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Shorten Myopic Axial Length with Repeated Low-lever Laser Light Therapy

Zhou Lei, Qiu Kaikai, William Bruce

Published in International Journal of Ophthalmology & Visual Science (Volume 6, Issue 2)

Received: 1 May 2021 Accepted: 18 June 2021 Published: 26 June 2021

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Abstract

Purpose: This study was to confirm that repeated low-lever laser light therapy (LLLT) could control myopic axial length (AL) elongation. Methods: Twenty myopia, 5 to 13 years old, were included in this study. All subjects kept daily repeated therapy with LLLT for mean 3 months; According to the baseline AL (> 24.40 mm or not), and ages (> 10 years old or not), we built two age groups and two AL groups. The AL between baseline and follow-up as well as different groups were all tested by SPSS 26.0, respectively. Results: 85% and 75% of AL were shortened for the right and left compared with those of baseline, respectively. The follow-up right and left AL were both significantly shortened (P=.002, P=.003, respectively) from baseline mean right AL 24.52 ± 1.01 mm, left AL 24.51 ± 0.96 mm, to 24.41 ± 0.98 mm (-0.11 mm right AL shortened amount) and 24.42 ± 0.93 (-0.09 mm left AL shortened amount), respectively. Long baseline AL group was significantly (P=.02, P=.03) shortened more AL than those of small baseline AL group for both right and left AL (-0.17 mm versus -0.05 mm, P <.001, respectively). From age group aspect, although it was also significant difference changed (shortened) for right AL (P=.008), but not for left AL (P=.051). Conclusions: LLLT could control myopia axial length progression.

Published in	International Journal of Ophthalmology & Visual Science (Volume 6, Issue 2)
DOI	10.11648/j.ijovs.20210602.22
Page(s)	144-149
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Myopia, Low-Lever Laser Light, Axial Length

References

[1]	Gong Q, Janowski M, Luo M, et al. Share Efficacy and Adverse Effects of Atropine in Childhood Myopia: A Meta-analysis. JAMA Ophthalmol 2017; 135 (6): 624-30.
[2]	Hiraoka T, Kakita T, Okamoto F, et al. Long-term Effect of Overnight Orthokeratology on Axial Length Elongation in Childhood Myopia: A 5-year Follow-up Study. Invest Ophthalmol Vis Sci 2012; 53: 3913–19.
[3]	Chamberlain P, Peixoto-de-Matos SC, Logan NS, Ngo C, Jones D, Young G. A 3-year Randomized Clinical Trial of MiSight Lenses for Myopia Control. Optom Vis Sci 2019; 96 (8): 556-67.
[4]	A Review of Current Concepts of the Etiology and Treatment of Myopia. Eye Contact Lens 2018; 44 (4): 231– 47.
[5]	Nickla DL, et al., Myopic Defocus in the Evening is More Effective at Inhibiting Eye Growth than Defocus in the Morning: Effects on Rhythms in Axial Length and Choroid Thickness in Chicks. Exp Eye Res 2017; 154: 104–15.
[6]	Burfield HJ, Patel NB, and Ostrin LA, Ocular Biometric Diurnal Rhythms in Emmetropic and Myopic Adults. Invest Ophthalmol Vis Sci 2018. 59 (12): 5176–87.
[7]	Xiong F, Mao T, Liao H, etc. Orthokeratology and Low-Intensity Laser Therapy for Slowing the Progression of Myopia in Children. Biomed Res Int. 2021 Jan 27; 2021: 8915867.
[8]	Sankaridurg P, Bakaraju RC, Naduvilath T, Chen X, Weng R, Tilia D, Xu P, Li W, Conrad F, Smith EL 3rd, Ehrmann K. Myopia Control with Novel Central and Peripheral Plus Contact Lenses and Extended Depth of Focus Contact Lenses: 2 Year Results from a Randomised Clinical Trial. Ophthalmic Physiol Opt 2019; 39 (4): 294-307.
[9]	Wang M, Schaeffel F, Jiang B, Feldkaemper M. Effects of Light of Different Spectral Composition on Refractive Development and Retinal Dopamine in Chicks. Invest Ophthalmol Vis Sci. 2018 Sep 4; 59 (11): 4413-24.
[10]	Foulds WS, Barathi VA, and Luu CD, Progressive Myopia or Hyperopia can be Induced in Chicks and Reversed by Manipulation of the Chromaticity of Ambient Light. Invest Ophthalmol Vis Sci 2013; 54 (13): 8004–12.
[11]	The Effects of Light Sources with Different Spectral Structures on Ocular Axial Length in Rainbow Trout (Oncorhynchus mykiss). Exp Eye Res 2016; 151: 212-21.
[12]	Jiang L, et al., Interactions of Chromatic and Lens-induced Defocus During Visual Control of Eye Growth in Guinea Pigs (Cavia Porcellus). Vision Res 2014; 94: 24–32.
[13]	Smith EL 3rd, Hung LF, Arumugam B, Holden BA, Neitz M, Neitz J. Effects of Long-Wavelength Lighting on Refractive Development in Infant Rhesus Monkeys. Invest Ophthalmol Vis Sci. 2015; 56 (11): 6490-500.
[14]	Gawne TJ, Ward AH, Norton TT. Long-wavelength (red) Light Produces Hyperopia in Juvenile and Adolescent Tree Shrews. Vision Res. 2017 Nov; 140: 55-65.
[15]	Ward AH, Norton TT, Huisingh CE, Gawne TJ. Share. The Hyperopic Effect of Narrow-band Long-wavelength Light in Tree Shrews Increases Non-linearly with Duration. Vision Res. 2018 May; 146-147: 9-17.
[16]	Karu TI, Pyatibrat LV, Kolyakov SF, Afanasyeva NI. Absorption Measurements of a Cell Monolayer Relevant to Phototherapy: Reduction of Cytochrome C Oxidase Under Near IR Radiation. J Photochem Photobiol B 2005; 81: 98-106.
[17]	Zhang Y, Song S, Fong CC, et al. cDNA Microarray Analysis of Gene Expression Profiles in Human Fibroblast Cells Irradiated with Red Light. J Invest Dermatol 2003; 120: 849-57.
[18]	Bjordal JM, Couppe C, Chow RT, et al. A Systematic Review of Low Level Laser Therapy with Location-Specific Doses for Pain from Chronic Joint Disorders. Aust J Physiother 2003; 49: 107-16.
[19]	Peplow PV, Chung TY, Baxter GD. Laser Photobiomodulation of Wound Healing: a Review of Experimental Studies in Mouse and Rat Animal Models. Photomed Laser Surg 2010; 28: 291-325.
[20]	Salehpour F, Mahmoudi J, Kamari F,, et al. Brain Photobiomodulation Therapy: a Narrative Review. Mol Neurobiol 2018; 55 (8): 6601-36.
[21]	Chung H, Dai T, Sharma SK, et al. The Nuts and Bolts of Low-Level Laser (Light) Therapy. Ann Biomed Eng 2012; 40 (2): 516-33.
[22]	Stausholm MB, Naterstad IF, Joensen J, et al. Efficacy of Low-Level Laser Therapy on Pain and Disability in Knee Osteoarthritis: Systematic Review and Meta-Analysis of Randomised Placebo-Controlled Trials. BMJ Open 2019; 9 (10): e031142.
[23]	Yeh SW, Hong CH, Shih MC, et al. Low-Level Laser Therapy for Fibromyalgia: A Systematic Review and Meta-Analysis. Pain Physician 2019; 22 (3): 241-54.
[24]	Merry GF, Munk MR, Dotson RS, et al. Photobiomodulation Reduces Drusen Volume and Improves Visual Acuity and Contrast Sensitivity in Dry Age-Related Macular Degeneration. Acta Ophthalmol 2017; 95 (4): e270-7.
[25]	Geneva II. Photobiomodulation for the Treatment of Retinal Diseases: a Review. Int J Ophthalmol 2016; 9 (1): 145-52.
[26]	Rucker F. Monochromatic and White Light and the Regulation of Eye Growth. Exp Eye Res 2019; 184: 172-82.

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APA Style

Zhou Lei, Qiu Kaikai, William Bruce. (2021). Shorten Myopic Axial Length with Repeated Low-lever Laser Light Therapy. International Journal of Ophthalmology & Visual Science, 6(2), 144-149. https://doi.org/10.11648/j.ijovs.20210602.22

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ACS Style

Zhou Lei; Qiu Kaikai; William Bruce. Shorten Myopic Axial Length with Repeated Low-lever Laser Light Therapy. Int. J. Ophthalmol. Vis. Sci. 2021, 6(2), 144-149. doi: 10.11648/j.ijovs.20210602.22

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AMA Style

Zhou Lei, Qiu Kaikai, William Bruce. Shorten Myopic Axial Length with Repeated Low-lever Laser Light Therapy. Int J Ophthalmol Vis Sci. 2021;6(2):144-149. doi: 10.11648/j.ijovs.20210602.22

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@article{10.11648/j.ijovs.20210602.22,
  author = {Zhou Lei and Qiu Kaikai and William Bruce},
  title = {Shorten Myopic Axial Length with Repeated Low-lever Laser Light Therapy},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {6},
  number = {2},
  pages = {144-149},
  doi = {10.11648/j.ijovs.20210602.22},
  url = {https://doi.org/10.11648/j.ijovs.20210602.22},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210602.22},
  abstract = {Purpose: This study was to confirm that repeated low-lever laser light therapy (LLLT) could control myopic axial length (AL) elongation. Methods: Twenty myopia, 5 to 13 years old, were included in this study. All subjects kept daily repeated therapy with LLLT for mean 3 months; According to the baseline AL (> 24.40 mm or not), and ages (> 10 years old or not), we built two age groups and two AL groups. The AL between baseline and follow-up as well as different groups were all tested by SPSS 26.0, respectively. Results: 85% and 75% of AL were shortened for the right and left compared with those of baseline, respectively. The follow-up right and left AL were both significantly shortened (P=.002, P=.003, respectively) from baseline mean right AL 24.52 ± 1.01 mm, left AL 24.51 ± 0.96 mm, to 24.41 ± 0.98 mm (-0.11 mm right AL shortened amount) and 24.42 ± 0.93 (-0.09 mm left AL shortened amount), respectively. Long baseline AL group was significantly (P=.02, P=.03) shortened more AL than those of small baseline AL group for both right and left AL (-0.17 mm versus -0.05 mm, P <.001, respectively). From age group aspect, although it was also significant difference changed (shortened) for right AL (P=.008), but not for left AL (P=.051). Conclusions: LLLT could control myopia axial length progression.},
 year = {2021}
}

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TY  - JOUR
T1  - Shorten Myopic Axial Length with Repeated Low-lever Laser Light Therapy
AU  - Zhou Lei
AU  - Qiu Kaikai
AU  - William Bruce
Y1  - 2021/06/26
PY  - 2021
N1  - https://doi.org/10.11648/j.ijovs.20210602.22
DO  - 10.11648/j.ijovs.20210602.22
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 144
EP  - 149
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20210602.22
AB  - Purpose: This study was to confirm that repeated low-lever laser light therapy (LLLT) could control myopic axial length (AL) elongation. Methods: Twenty myopia, 5 to 13 years old, were included in this study. All subjects kept daily repeated therapy with LLLT for mean 3 months; According to the baseline AL (> 24.40 mm or not), and ages (> 10 years old or not), we built two age groups and two AL groups. The AL between baseline and follow-up as well as different groups were all tested by SPSS 26.0, respectively. Results: 85% and 75% of AL were shortened for the right and left compared with those of baseline, respectively. The follow-up right and left AL were both significantly shortened (P=.002, P=.003, respectively) from baseline mean right AL 24.52 ± 1.01 mm, left AL 24.51 ± 0.96 mm, to 24.41 ± 0.98 mm (-0.11 mm right AL shortened amount) and 24.42 ± 0.93 (-0.09 mm left AL shortened amount), respectively. Long baseline AL group was significantly (P=.02, P=.03) shortened more AL than those of small baseline AL group for both right and left AL (-0.17 mm versus -0.05 mm, P <.001, respectively). From age group aspect, although it was also significant difference changed (shortened) for right AL (P=.008), but not for left AL (P=.051). Conclusions: LLLT could control myopia axial length progression.
VL  - 6
IS  - 2
ER  -

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Author Information

Zhou Lei

Ning Bo Eye Hospital, Ningbo, China
Qiu Kaikai

Fuzhou South East Eye Hospital, Fuzhou, China
William Bruce

Seattle Vision Care Center, Seattle, USA

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Plain Text BibTeX RIS

APA Style

Zhou Lei, Qiu Kaikai, William Bruce. (2021). Shorten Myopic Axial Length with Repeated Low-lever Laser Light Therapy. International Journal of Ophthalmology & Visual Science, 6(2), 144-149. https://doi.org/10.11648/j.ijovs.20210602.22

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ACS Style

Zhou Lei; Qiu Kaikai; William Bruce. Shorten Myopic Axial Length with Repeated Low-lever Laser Light Therapy. Int. J. Ophthalmol. Vis. Sci. 2021, 6(2), 144-149. doi: 10.11648/j.ijovs.20210602.22

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AMA Style

Zhou Lei, Qiu Kaikai, William Bruce. Shorten Myopic Axial Length with Repeated Low-lever Laser Light Therapy. Int J Ophthalmol Vis Sci. 2021;6(2):144-149. doi: 10.11648/j.ijovs.20210602.22

Copy | Download

@article{10.11648/j.ijovs.20210602.22,
  author = {Zhou Lei and Qiu Kaikai and William Bruce},
  title = {Shorten Myopic Axial Length with Repeated Low-lever Laser Light Therapy},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {6},
  number = {2},
  pages = {144-149},
  doi = {10.11648/j.ijovs.20210602.22},
  url = {https://doi.org/10.11648/j.ijovs.20210602.22},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210602.22},
  abstract = {Purpose: This study was to confirm that repeated low-lever laser light therapy (LLLT) could control myopic axial length (AL) elongation. Methods: Twenty myopia, 5 to 13 years old, were included in this study. All subjects kept daily repeated therapy with LLLT for mean 3 months; According to the baseline AL (> 24.40 mm or not), and ages (> 10 years old or not), we built two age groups and two AL groups. The AL between baseline and follow-up as well as different groups were all tested by SPSS 26.0, respectively. Results: 85% and 75% of AL were shortened for the right and left compared with those of baseline, respectively. The follow-up right and left AL were both significantly shortened (P=.002, P=.003, respectively) from baseline mean right AL 24.52 ± 1.01 mm, left AL 24.51 ± 0.96 mm, to 24.41 ± 0.98 mm (-0.11 mm right AL shortened amount) and 24.42 ± 0.93 (-0.09 mm left AL shortened amount), respectively. Long baseline AL group was significantly (P=.02, P=.03) shortened more AL than those of small baseline AL group for both right and left AL (-0.17 mm versus -0.05 mm, P <.001, respectively). From age group aspect, although it was also significant difference changed (shortened) for right AL (P=.008), but not for left AL (P=.051). Conclusions: LLLT could control myopia axial length progression.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Shorten Myopic Axial Length with Repeated Low-lever Laser Light Therapy
AU  - Zhou Lei
AU  - Qiu Kaikai
AU  - William Bruce
Y1  - 2021/06/26
PY  - 2021
N1  - https://doi.org/10.11648/j.ijovs.20210602.22
DO  - 10.11648/j.ijovs.20210602.22
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 144
EP  - 149
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20210602.22
AB  - Purpose: This study was to confirm that repeated low-lever laser light therapy (LLLT) could control myopic axial length (AL) elongation. Methods: Twenty myopia, 5 to 13 years old, were included in this study. All subjects kept daily repeated therapy with LLLT for mean 3 months; According to the baseline AL (> 24.40 mm or not), and ages (> 10 years old or not), we built two age groups and two AL groups. The AL between baseline and follow-up as well as different groups were all tested by SPSS 26.0, respectively. Results: 85% and 75% of AL were shortened for the right and left compared with those of baseline, respectively. The follow-up right and left AL were both significantly shortened (P=.002, P=.003, respectively) from baseline mean right AL 24.52 ± 1.01 mm, left AL 24.51 ± 0.96 mm, to 24.41 ± 0.98 mm (-0.11 mm right AL shortened amount) and 24.42 ± 0.93 (-0.09 mm left AL shortened amount), respectively. Long baseline AL group was significantly (P=.02, P=.03) shortened more AL than those of small baseline AL group for both right and left AL (-0.17 mm versus -0.05 mm, P <.001, respectively). From age group aspect, although it was also significant difference changed (shortened) for right AL (P=.008), but not for left AL (P=.051). Conclusions: LLLT could control myopia axial length progression.
VL  - 6
IS  - 2
ER  -

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