Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking

Ahmed Mohamed Reda; Ahmed Shafek Elridy; Reham Fawzy Elshinawy

doi:doi:10.11648/j.ijovs.20180301.12

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Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking

Ahmed Mohamed Reda, Ahmed Shafek Elridy, Reham Fawzy Elshinawy

Published in International Journal of Ophthalmology & Visual Science (Volume 3, Issue 1)

Received: 4 February 2018 Accepted: 24 February 2018 Published: 24 March 2018

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Abstract

This retrospective study was designed to evaluate the efficacy and safety of simultaneous topography-guided PRK plus cross linking for patients with mild to moderate keratoconus and to evaluate the stability of the cone. The patients were evaluated over two years for the progression and stability of the cone by the Allegro Pentacam Oculyzer to assess the changes of corneal curvatures (K readings) and the stability of the cone after the surgery and evaluating uncorrected distance (UDVA) and best corrected (CDVA) visual acuities. The follow-up results showed that UDVA improved from 0.4±0.3 to 0.7±0.1 and CDVA changed from 0.6±0.1 to 0.8±0.1 (P < 0.001). The keratometry value decreased from 44.1±2.2 to 41.4±1.6 D for K1, and from 46.4±2.6 to 43.5±1.7 for K2 (P < 0.001). This combined procedure offers a promising method to stabilize the corneal surface with reducing higher order aberrations so enhancing quality of vision in keratoconus patients.

Published in	International Journal of Ophthalmology & Visual Science (Volume 3, Issue 1)
DOI	10.11648/j.ijovs.20180301.12
Page(s)	7-11
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Keratoconus, Topography, Cross-Linking, PRK

References

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[2]	Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol 2003; 135:620-7.
[3]	Asri D, Touboul D, Fournié P, Malet F, Garra C, Gallois A, et al. Corneal collagen crosslinking in progressive keratoconus: Multicenter results from the French National Reference Center for Keratoconus. J Cataract Refract Surg 2011; 37:2137-43.
[4]	Derakhshan A, Shandiz JH, Ahadi M, Daneshvar R, Esmaily H. Short-term outcomes of collagen crosslinking for early keratoconus. J Ophthalmic Vis Res 2011; 6:155-9.
[5]	Wollensak G, Spoerl E, Seiler T. Stress-strain measurements of human and porcine corneas after riboflavin-ultraviolet-A-induced cross-linking. J Cataract Refract Surg 2003; 29:1780-5.
[6]	Kohlhaas M, Spoerl E, Schilde T, Unger G, Wittig C, Pillunat LE. Biomechanical evidence of the distribution of cross-links in corneas treated with riboflavin and ultraviolet a light. J Cataract Refract Surg 2006; 32:279-83.
[7]	Spoerl E, Wollensak G, Seiler T. Increased resistance of crosslinked cornea against enzymatic digestion. Curr Eye Res 2004; 29:35-40.
[8]	Koller T, Mrochen M, Seiler T. Complication and failure rates after corneal crosslinking. J Cataract Refract Surg 2009; 35:1358-62.
[9]	Greenstein SA, Fry KL, Hersh PS. Corneal topography indices after corneal collagen crosslinking for keratoconus and corneal ectasia: One-year results. J Cataract Refract Surg 2011; 37:1282-90.
[10]	Sakla H, Altroudi W, Munoz G, Albarran Diego C. Simultaneous topography-guided partial photorefractive keratectomy and corneal collagen crosslinking for keratoconus. J cataract Refract Surg. 2014 Sep; 40 (9): 1430-8.
[11]	Vinciguerra P, Albè E, Trazza S, Rosetta P, Vinciguerra R, Seiler T, et al. Refractive, topographic, tomographic, and aberrometric analysis of keratoconic eyes undergoing corneal cross-linking. Ophthalmology 2009; 116:369-78.
[12]	Stojanovic A, Zhang J, Chen X, et al. Topography- guided transepithelial surface ablation followed by corneal collagen crosslinking performed in a single procedure for the treatment of keratoconus and pellucid marginal degeneration. J Refract Surg. 2010; 26: 145-52.
[13]	Mukherjee AN, Vasilis Selmis, Iaonnis Aslanides. Transepithelial Phototorefractive Keratectomy with Crosslinking for Keratoconus. Open Ophthalmol J. 2013; 7: 63-68.

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APA Style

Ahmed Mohamed Reda, Ahmed Shafek Elridy, Reham Fawzy Elshinawy. (2018). Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking. International Journal of Ophthalmology & Visual Science, 3(1), 7-11. https://doi.org/10.11648/j.ijovs.20180301.12

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ACS Style

Ahmed Mohamed Reda; Ahmed Shafek Elridy; Reham Fawzy Elshinawy. Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking. Int. J. Ophthalmol. Vis. Sci. 2018, 3(1), 7-11. doi: 10.11648/j.ijovs.20180301.12

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AMA Style

Ahmed Mohamed Reda, Ahmed Shafek Elridy, Reham Fawzy Elshinawy. Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking. Int J Ophthalmol Vis Sci. 2018;3(1):7-11. doi: 10.11648/j.ijovs.20180301.12

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@article{10.11648/j.ijovs.20180301.12,
  author = {Ahmed Mohamed Reda and Ahmed Shafek Elridy and Reham Fawzy Elshinawy},
  title = {Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {3},
  number = {1},
  pages = {7-11},
  doi = {10.11648/j.ijovs.20180301.12},
  url = {https://doi.org/10.11648/j.ijovs.20180301.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20180301.12},
  abstract = {This retrospective study was designed to evaluate the efficacy and safety of simultaneous topography-guided PRK plus cross linking for patients with mild to moderate keratoconus and to evaluate the stability of the cone. The patients were evaluated over two years for the progression and stability of the cone by the Allegro Pentacam Oculyzer to assess the changes of corneal curvatures (K readings) and the stability of the cone after the surgery and evaluating uncorrected distance (UDVA) and best corrected (CDVA) visual acuities. The follow-up results showed that UDVA improved from 0.4±0.3 to 0.7±0.1 and CDVA changed from 0.6±0.1 to 0.8±0.1 (P < 0.001). The keratometry value decreased from 44.1±2.2 to 41.4±1.6 D for K1, and from 46.4±2.6 to 43.5±1.7 for K2 (P < 0.001). This combined procedure offers a promising method to stabilize the corneal surface with reducing higher order aberrations so enhancing quality of vision in keratoconus patients.},
 year = {2018}
}

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TY  - JOUR
T1  - Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking
AU  - Ahmed Mohamed Reda
AU  - Ahmed Shafek Elridy
AU  - Reham Fawzy Elshinawy
Y1  - 2018/03/24
PY  - 2018
N1  - https://doi.org/10.11648/j.ijovs.20180301.12
DO  - 10.11648/j.ijovs.20180301.12
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 7
EP  - 11
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20180301.12
AB  - This retrospective study was designed to evaluate the efficacy and safety of simultaneous topography-guided PRK plus cross linking for patients with mild to moderate keratoconus and to evaluate the stability of the cone. The patients were evaluated over two years for the progression and stability of the cone by the Allegro Pentacam Oculyzer to assess the changes of corneal curvatures (K readings) and the stability of the cone after the surgery and evaluating uncorrected distance (UDVA) and best corrected (CDVA) visual acuities. The follow-up results showed that UDVA improved from 0.4±0.3 to 0.7±0.1 and CDVA changed from 0.6±0.1 to 0.8±0.1 (P < 0.001). The keratometry value decreased from 44.1±2.2 to 41.4±1.6 D for K1, and from 46.4±2.6 to 43.5±1.7 for K2 (P < 0.001). This combined procedure offers a promising method to stabilize the corneal surface with reducing higher order aberrations so enhancing quality of vision in keratoconus patients.
VL  - 3
IS  - 1
ER  -

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Author Information

Ahmed Mohamed Reda

Department of Ophthalmology, Faculty of Medicine, Ain Sham University, Cairo, Egypt
Ahmed Shafek Elridy

Department of Ophthalmology, Faculty of Medicine, Ain Sham University, Cairo, Egypt
Reham Fawzy Elshinawy

Department of Ophthalmology, Faculty of Medicine, Ain Sham University, Cairo, Egypt

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APA Style

Ahmed Mohamed Reda, Ahmed Shafek Elridy, Reham Fawzy Elshinawy. (2018). Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking. International Journal of Ophthalmology & Visual Science, 3(1), 7-11. https://doi.org/10.11648/j.ijovs.20180301.12

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ACS Style

Ahmed Mohamed Reda; Ahmed Shafek Elridy; Reham Fawzy Elshinawy. Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking. Int. J. Ophthalmol. Vis. Sci. 2018, 3(1), 7-11. doi: 10.11648/j.ijovs.20180301.12

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AMA Style

Ahmed Mohamed Reda, Ahmed Shafek Elridy, Reham Fawzy Elshinawy. Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking. Int J Ophthalmol Vis Sci. 2018;3(1):7-11. doi: 10.11648/j.ijovs.20180301.12

Copy | Download

@article{10.11648/j.ijovs.20180301.12,
  author = {Ahmed Mohamed Reda and Ahmed Shafek Elridy and Reham Fawzy Elshinawy},
  title = {Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {3},
  number = {1},
  pages = {7-11},
  doi = {10.11648/j.ijovs.20180301.12},
  url = {https://doi.org/10.11648/j.ijovs.20180301.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20180301.12},
  abstract = {This retrospective study was designed to evaluate the efficacy and safety of simultaneous topography-guided PRK plus cross linking for patients with mild to moderate keratoconus and to evaluate the stability of the cone. The patients were evaluated over two years for the progression and stability of the cone by the Allegro Pentacam Oculyzer to assess the changes of corneal curvatures (K readings) and the stability of the cone after the surgery and evaluating uncorrected distance (UDVA) and best corrected (CDVA) visual acuities. The follow-up results showed that UDVA improved from 0.4±0.3 to 0.7±0.1 and CDVA changed from 0.6±0.1 to 0.8±0.1 (P < 0.001). The keratometry value decreased from 44.1±2.2 to 41.4±1.6 D for K1, and from 46.4±2.6 to 43.5±1.7 for K2 (P < 0.001). This combined procedure offers a promising method to stabilize the corneal surface with reducing higher order aberrations so enhancing quality of vision in keratoconus patients.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Two Years Follow up Evaluating Progression of Ectasia for Keratoconus Patients Treated with Simultaneous Topography - Guided PRK Plus Cross Linking
AU  - Ahmed Mohamed Reda
AU  - Ahmed Shafek Elridy
AU  - Reham Fawzy Elshinawy
Y1  - 2018/03/24
PY  - 2018
N1  - https://doi.org/10.11648/j.ijovs.20180301.12
DO  - 10.11648/j.ijovs.20180301.12
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 7
EP  - 11
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20180301.12
AB  - This retrospective study was designed to evaluate the efficacy and safety of simultaneous topography-guided PRK plus cross linking for patients with mild to moderate keratoconus and to evaluate the stability of the cone. The patients were evaluated over two years for the progression and stability of the cone by the Allegro Pentacam Oculyzer to assess the changes of corneal curvatures (K readings) and the stability of the cone after the surgery and evaluating uncorrected distance (UDVA) and best corrected (CDVA) visual acuities. The follow-up results showed that UDVA improved from 0.4±0.3 to 0.7±0.1 and CDVA changed from 0.6±0.1 to 0.8±0.1 (P < 0.001). The keratometry value decreased from 44.1±2.2 to 41.4±1.6 D for K1, and from 46.4±2.6 to 43.5±1.7 for K2 (P < 0.001). This combined procedure offers a promising method to stabilize the corneal surface with reducing higher order aberrations so enhancing quality of vision in keratoconus patients.
VL  - 3
IS  - 1
ER  -

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