To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage

Zhang Yanping; Zhang Pan; Zhang Wei; Wu Tiejun; Zhu Guanglin; Duan Qifeng

doi:doi:10.11648/j.ijn.20210502.11

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To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage

Zhang Yanping, Zhang Pan, Zhang Wei, Wu Tiejun, Zhu Guanglin, Duan Qifeng

Published in International Journal of Neurosurgery (Volume 5, Issue 2)

Received: 15 June 2021 Accepted: 2 July 2021 Published: 15 July 2021

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Abstract

Objective: To investigate the decrease of mortality and disability rate of severe ventricular system hemorrhage by catheter drainage and UK dissolution. Methods: From January 2015 to January 2020, 78 cases of primary severe ventricular hemorrhage and 47 cases of thalamic hematoma had broken into the ventricular system by admitted, all of which were caused by hypertension arteriosclerosis. A respectively adopt the double eminence F10 silicone tube line hemorrhage or hemorrhage drainage, drain and intraoperative all press automatic drainage device, and at the same time CT directional line thalamic hematoma drainage, pipe emptying and postoperative introcerebral hematoma and interior cavity at different times each injection urokinase solute 30000-50000 units, and lumbar puncture or with lumbar cistem catheter drainage, large cavity of thalamic hematoma and the original secondary intraventricular hemorrhage drainage time respectively for 3-4 d and 4-5 d, an average of 4.5 d extubation time. Results: After 6 months of follow-up, GOS and ADL grading were used to evaluate the recovery and self-care ability. GOS grading was 5points in 72 cases, 4 points in 41 cases, 3 points in 12 cases. ADL grading was Grade I in 69 cases, Grade II in 40 cases, Grade III in 5 cases, Grade IV in 6 cases, and Grade V in 5 cases (including 3 deaths). Among the 3 cases who died after operation, either 2 case suffered from primary whole ventricular hemorrhage combined with cerebral hernia, 1 case suffered from secondary hemorrhage combined with respiratory and circulatory failure caused by dilated hemocast of four ventricles. Sometime whith association communicating hydrocephalus in 3 cases that is underwent brain-peritoneal cerebrospinal fluid shunt. Conclusion: Empty and drainage of ventricular system hemorrhage and paraventricular thalamic hematoma which is can significantly reduce the morbidity and mortality.

Published in	International Journal of Neurosurgery (Volume 5, Issue 2)
DOI	10.11648/j.ijn.20210502.11
Page(s)	57-61
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Severe Intraventricular Hemorrhage, Original Position Replcement, External Drainage, Clinical Effction

References

[1]	Lin Chao, Wang Qiao, et al. Comparison of clinical characteristics of primary and secondary intraventricular hemorrhage [J]. Journal of Clinical Neurology, 2015, 28 (4) 308.
[2]	Wang Shaofei, Guo Jinguang, et al. Effect of urokinase perfusion with different retention time on coagulation and fibrous system in severe ventricular hemorrhage [J]. Trauma and Acute Care Medicine, 2018, 6 (4): 416.
[3]	Abuzergungor, MD, Serhat Baydin, MD, Erikh. Middebrooks, MD; et al: The white matter tracts of the cerebrum in ventricular surgery and hydrocephalus. [J]. Neurosurg 2017, 126, 955.
[4]	Zhou GZ, Yang F, TONG MF, et al. Clinical characteristics and prognostic factors of 41 patients with primary ventricular hemorrhage [J]. Chinese Journal of General Practitioners, 2018, 16 (11): 1804-1.
[5]	Wei Jianhui, Tian Yanan, Zhao Wangsen, et al. Neuroendoscopic hematoma removal was performed for severe cases Clinical study of ventricular hemorrhage [J]. Chin J Neurosurgery, 19, 35 (4): 349-350.
[6]	ZHang Wei, Song Yanjie, Liu Xuchang, et al. Effect of bilateral ventricular catheterization hematoma aspiration and ventricular perfusion on severe intraventricular hemorrhage [J]. Shandong Pharmaceutical 2018 58 (26): 51.
[7]	Chen XJ, Ni Zhihong, Effect of two-needle minimally invasive treatment of hypertensive ventricular hemorrhage [J]. Chin J Geriatr, 2015, 35 (6): 1679.
[8]	Yang Ping Lai, Zhang Yuanyuan, Zhou Litian, et al. Minimally invasive external ventricular drainage in the treatment of 39 cases of intraventricular hemorrhage [J], Chinese Journal of Clinical Neurosurgery, 2015, 12 (5): 378.
[9]	Binghui Qiu, Songtao Qi. Discussion on prevention of infection associated with external ventricular drainage [J]. Chinese Journal of Trauma, 2019, 35 (3): 205.
[10]	Shen Yunlong, Liu Jiajin, QI Songtao, et al. Risk factors of intracranial infection after external drainage for ventricular hemorrhage [J]. Chinese Journal of Neuropsychiatric Diseases, 2015, 41 (12): 708.
[11]	Zhang Yanping, Zhu Shugan, et al. Surgical treatment of intracranial hemorrhage [M]. Beijing People's Military Medical Publishing House. 2010 67.

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APA Style

Zhang Yanping, Zhang Pan, Zhang Wei, Wu Tiejun, Zhu Guanglin, et al. (2021). To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage. International Journal of Neurosurgery, 5(2), 57-61. https://doi.org/10.11648/j.ijn.20210502.11

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ACS Style

Zhang Yanping; Zhang Pan; Zhang Wei; Wu Tiejun; Zhu Guanglin, et al. To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage. Int. J. Neurosurg. 2021, 5(2), 57-61. doi: 10.11648/j.ijn.20210502.11

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AMA Style

Zhang Yanping, Zhang Pan, Zhang Wei, Wu Tiejun, Zhu Guanglin, et al. To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage. Int J Neurosurg. 2021;5(2):57-61. doi: 10.11648/j.ijn.20210502.11

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@article{10.11648/j.ijn.20210502.11,
  author = {Zhang Yanping and Zhang Pan and Zhang Wei and Wu Tiejun and Zhu Guanglin and Duan Qifeng},
  title = {To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage},
  journal = {International Journal of Neurosurgery},
  volume = {5},
  number = {2},
  pages = {57-61},
  doi = {10.11648/j.ijn.20210502.11},
  url = {https://doi.org/10.11648/j.ijn.20210502.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijn.20210502.11},
  abstract = {Objective: To investigate the decrease of mortality and disability rate of severe ventricular system hemorrhage by catheter drainage and UK dissolution. Methods: From January 2015 to January 2020, 78 cases of primary severe ventricular hemorrhage and 47 cases of thalamic hematoma had broken into the ventricular system by admitted, all of which were caused by hypertension arteriosclerosis. A respectively adopt the double eminence F10 silicone tube line hemorrhage or hemorrhage drainage, drain and intraoperative all press automatic drainage device, and at the same time CT directional line thalamic hematoma drainage, pipe emptying and postoperative introcerebral hematoma and interior cavity at different times each injection urokinase solute 30000-50000 units, and lumbar puncture or with lumbar cistem catheter drainage, large cavity of thalamic hematoma and the original secondary intraventricular hemorrhage drainage time respectively for 3-4 d and 4-5 d, an average of 4.5 d extubation time. Results: After 6 months of follow-up, GOS and ADL grading were used to evaluate the recovery and self-care ability. GOS grading was 5points in 72 cases, 4 points in 41 cases, 3 points in 12 cases. ADL grading was Grade I in 69 cases, Grade II in 40 cases, Grade III in 5 cases, Grade IV in 6 cases, and Grade V in 5 cases (including 3 deaths). Among the 3 cases who died after operation, either 2 case suffered from primary whole ventricular hemorrhage combined with cerebral hernia, 1 case suffered from secondary hemorrhage combined with respiratory and circulatory failure caused by dilated hemocast of four ventricles. Sometime whith association communicating hydrocephalus in 3 cases that is underwent brain-peritoneal cerebrospinal fluid shunt. Conclusion: Empty and drainage of ventricular system hemorrhage and paraventricular thalamic hematoma which is can significantly reduce the morbidity and mortality.},
 year = {2021}
}

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TY  - JOUR
T1  - To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage
AU  - Zhang Yanping
AU  - Zhang Pan
AU  - Zhang Wei
AU  - Wu Tiejun
AU  - Zhu Guanglin
AU  - Duan Qifeng
Y1  - 2021/07/15
PY  - 2021
N1  - https://doi.org/10.11648/j.ijn.20210502.11
DO  - 10.11648/j.ijn.20210502.11
T2  - International Journal of Neurosurgery
JF  - International Journal of Neurosurgery
JO  - International Journal of Neurosurgery
SP  - 57
EP  - 61
PB  - Science Publishing Group
SN  - 2640-1959
UR  - https://doi.org/10.11648/j.ijn.20210502.11
AB  - Objective: To investigate the decrease of mortality and disability rate of severe ventricular system hemorrhage by catheter drainage and UK dissolution. Methods: From January 2015 to January 2020, 78 cases of primary severe ventricular hemorrhage and 47 cases of thalamic hematoma had broken into the ventricular system by admitted, all of which were caused by hypertension arteriosclerosis. A respectively adopt the double eminence F10 silicone tube line hemorrhage or hemorrhage drainage, drain and intraoperative all press automatic drainage device, and at the same time CT directional line thalamic hematoma drainage, pipe emptying and postoperative introcerebral hematoma and interior cavity at different times each injection urokinase solute 30000-50000 units, and lumbar puncture or with lumbar cistem catheter drainage, large cavity of thalamic hematoma and the original secondary intraventricular hemorrhage drainage time respectively for 3-4 d and 4-5 d, an average of 4.5 d extubation time. Results: After 6 months of follow-up, GOS and ADL grading were used to evaluate the recovery and self-care ability. GOS grading was 5points in 72 cases, 4 points in 41 cases, 3 points in 12 cases. ADL grading was Grade I in 69 cases, Grade II in 40 cases, Grade III in 5 cases, Grade IV in 6 cases, and Grade V in 5 cases (including 3 deaths). Among the 3 cases who died after operation, either 2 case suffered from primary whole ventricular hemorrhage combined with cerebral hernia, 1 case suffered from secondary hemorrhage combined with respiratory and circulatory failure caused by dilated hemocast of four ventricles. Sometime whith association communicating hydrocephalus in 3 cases that is underwent brain-peritoneal cerebrospinal fluid shunt. Conclusion: Empty and drainage of ventricular system hemorrhage and paraventricular thalamic hematoma which is can significantly reduce the morbidity and mortality.
VL  - 5
IS  - 2
ER  -

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Author Information

Zhang Yanping

Department of Neurosurgery, Center Hospital of Zi Mining Group, Zibo City, China
Zhang Pan

Department of Emergency, Linzi Qidu Hospital, Zibo City, China
Zhang Wei

Department of Surgery, Central Hospital of Zibo Mining Group, Zibo City, China
Wu Tiejun

Department of Surgery, Central Hospital of Zibo Mining Group, Zibo City, China
Zhu Guanglin

Department of Surgery, Central Hospital of Zibo Mining Group, Zibo City, China
Duan Qifeng

Department of Surgery, Central Hospital of Zibo Mining Group, Zibo City, China

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Plain Text BibTeX RIS

APA Style

Zhang Yanping, Zhang Pan, Zhang Wei, Wu Tiejun, Zhu Guanglin, et al. (2021). To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage. International Journal of Neurosurgery, 5(2), 57-61. https://doi.org/10.11648/j.ijn.20210502.11

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ACS Style

Zhang Yanping; Zhang Pan; Zhang Wei; Wu Tiejun; Zhu Guanglin, et al. To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage. Int. J. Neurosurg. 2021, 5(2), 57-61. doi: 10.11648/j.ijn.20210502.11

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AMA Style

Zhang Yanping, Zhang Pan, Zhang Wei, Wu Tiejun, Zhu Guanglin, et al. To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage. Int J Neurosurg. 2021;5(2):57-61. doi: 10.11648/j.ijn.20210502.11

Copy | Download

@article{10.11648/j.ijn.20210502.11,
  author = {Zhang Yanping and Zhang Pan and Zhang Wei and Wu Tiejun and Zhu Guanglin and Duan Qifeng},
  title = {To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage},
  journal = {International Journal of Neurosurgery},
  volume = {5},
  number = {2},
  pages = {57-61},
  doi = {10.11648/j.ijn.20210502.11},
  url = {https://doi.org/10.11648/j.ijn.20210502.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijn.20210502.11},
  abstract = {Objective: To investigate the decrease of mortality and disability rate of severe ventricular system hemorrhage by catheter drainage and UK dissolution. Methods: From January 2015 to January 2020, 78 cases of primary severe ventricular hemorrhage and 47 cases of thalamic hematoma had broken into the ventricular system by admitted, all of which were caused by hypertension arteriosclerosis. A respectively adopt the double eminence F10 silicone tube line hemorrhage or hemorrhage drainage, drain and intraoperative all press automatic drainage device, and at the same time CT directional line thalamic hematoma drainage, pipe emptying and postoperative introcerebral hematoma and interior cavity at different times each injection urokinase solute 30000-50000 units, and lumbar puncture or with lumbar cistem catheter drainage, large cavity of thalamic hematoma and the original secondary intraventricular hemorrhage drainage time respectively for 3-4 d and 4-5 d, an average of 4.5 d extubation time. Results: After 6 months of follow-up, GOS and ADL grading were used to evaluate the recovery and self-care ability. GOS grading was 5points in 72 cases, 4 points in 41 cases, 3 points in 12 cases. ADL grading was Grade I in 69 cases, Grade II in 40 cases, Grade III in 5 cases, Grade IV in 6 cases, and Grade V in 5 cases (including 3 deaths). Among the 3 cases who died after operation, either 2 case suffered from primary whole ventricular hemorrhage combined with cerebral hernia, 1 case suffered from secondary hemorrhage combined with respiratory and circulatory failure caused by dilated hemocast of four ventricles. Sometime whith association communicating hydrocephalus in 3 cases that is underwent brain-peritoneal cerebrospinal fluid shunt. Conclusion: Empty and drainage of ventricular system hemorrhage and paraventricular thalamic hematoma which is can significantly reduce the morbidity and mortality.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - To Investigate the Effect of Catheter Drainage and Urokinase Dissolution for Severe Ventricular System Hemorrhage
AU  - Zhang Yanping
AU  - Zhang Pan
AU  - Zhang Wei
AU  - Wu Tiejun
AU  - Zhu Guanglin
AU  - Duan Qifeng
Y1  - 2021/07/15
PY  - 2021
N1  - https://doi.org/10.11648/j.ijn.20210502.11
DO  - 10.11648/j.ijn.20210502.11
T2  - International Journal of Neurosurgery
JF  - International Journal of Neurosurgery
JO  - International Journal of Neurosurgery
SP  - 57
EP  - 61
PB  - Science Publishing Group
SN  - 2640-1959
UR  - https://doi.org/10.11648/j.ijn.20210502.11
AB  - Objective: To investigate the decrease of mortality and disability rate of severe ventricular system hemorrhage by catheter drainage and UK dissolution. Methods: From January 2015 to January 2020, 78 cases of primary severe ventricular hemorrhage and 47 cases of thalamic hematoma had broken into the ventricular system by admitted, all of which were caused by hypertension arteriosclerosis. A respectively adopt the double eminence F10 silicone tube line hemorrhage or hemorrhage drainage, drain and intraoperative all press automatic drainage device, and at the same time CT directional line thalamic hematoma drainage, pipe emptying and postoperative introcerebral hematoma and interior cavity at different times each injection urokinase solute 30000-50000 units, and lumbar puncture or with lumbar cistem catheter drainage, large cavity of thalamic hematoma and the original secondary intraventricular hemorrhage drainage time respectively for 3-4 d and 4-5 d, an average of 4.5 d extubation time. Results: After 6 months of follow-up, GOS and ADL grading were used to evaluate the recovery and self-care ability. GOS grading was 5points in 72 cases, 4 points in 41 cases, 3 points in 12 cases. ADL grading was Grade I in 69 cases, Grade II in 40 cases, Grade III in 5 cases, Grade IV in 6 cases, and Grade V in 5 cases (including 3 deaths). Among the 3 cases who died after operation, either 2 case suffered from primary whole ventricular hemorrhage combined with cerebral hernia, 1 case suffered from secondary hemorrhage combined with respiratory and circulatory failure caused by dilated hemocast of four ventricles. Sometime whith association communicating hydrocephalus in 3 cases that is underwent brain-peritoneal cerebrospinal fluid shunt. Conclusion: Empty and drainage of ventricular system hemorrhage and paraventricular thalamic hematoma which is can significantly reduce the morbidity and mortality.
VL  - 5
IS  - 2
ER  -

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