Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids

Farid Hidayat; Dian Pratiwi; Titus Kurnia; Taslim; Ahmad Syukri; Paskalis Indra; Muzakkir Amir; Peter Kabo; Robert Setiadji

doi:doi:10.11648/j.ijhpebs.20180401.12

Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids

Farid Hidayat, Dian Pratiwi, Titus Kurnia, Taslim, Ahmad Syukri, Paskalis Indra, Muzakkir Amir, Peter Kabo, Robert Setiadji

Published in International Journal of HIV/AIDS Prevention, Education and Behavioural Science (Volume 4, Issue 1)

Received: 23 February 2018 Accepted: 20 March 2018 Published: 12 April 2018

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Abstract

Background: People with Acquired Immunodeficiency Syndrome (AIDS) are at risk of developing structural and functional cardiac abnormalities that are unrelated to common cardiac risk factors (e.g. Hypertension, Diabetes Mellitus, Smoking habit). AIDS may be associated with chronic inflammation related to multiple factors related to the Human Immunodeficiency Virus (HIV) infection and its complications. Cardiac abnormality with AIDS may be subclinical and may present long before the onset of clinical heart failure symptoms. Objectives: To anticipate the risk of cardiovascular morbidity in people with AIDS. Methods: The researchers studied 52 people with AIDS in this observational cross-sectional study, which were further categorized into those with cluster of differentiation 4 (CD4) count of less than 200/mm3 and those with CD4 count of more than 200/mm3. Echocardiographic examinations were done to evaluate cardiac structural and functional values. Results: Mean age was 33 years old, predominantly male (71.2%). The group with a CD4 count of less than 200/mm3 showed higher Left Ventricular Mass Index (LVMI) values (113.08 vs. 39.99, p=0.012), a higher risk of developing diastolic dysfunction (OR 9.35, CI 95%, p=0.018) and pericardial effusion (OR 3.83, CI 95%, p=0.048). Conclusion: A CD4 count of less than 200/mm³ is associated with a higher risk of developing cardiac diastolic dysfunction and structural abnormalities.

Published in	International Journal of HIV/AIDS Prevention, Education and Behavioural Science (Volume 4, Issue 1)
DOI	10.11648/j.ijhpebs.20180401.12
Page(s)	5-10
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

HIV, AIDS, Echocardiography, Diastolic Dysfunction

References

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APA Style

Farid Hidayat, Dian Pratiwi, Titus Kurnia, Taslim, Ahmad Syukri, et al. (2018). Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids. International Journal of HIV/AIDS Prevention, Education and Behavioural Science, 4(1), 5-10. https://doi.org/10.11648/j.ijhpebs.20180401.12

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ACS Style

Farid Hidayat; Dian Pratiwi; Titus Kurnia; Taslim; Ahmad Syukri, et al. Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids. Int. J. HIV/AIDS Prev. Educ. Behav. Sci. 2018, 4(1), 5-10. doi: 10.11648/j.ijhpebs.20180401.12

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AMA Style

Farid Hidayat, Dian Pratiwi, Titus Kurnia, Taslim, Ahmad Syukri, et al. Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids. Int J HIV/AIDS Prev Educ Behav Sci. 2018;4(1):5-10. doi: 10.11648/j.ijhpebs.20180401.12

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@article{10.11648/j.ijhpebs.20180401.12,
  author = {Farid Hidayat and Dian Pratiwi and Titus Kurnia and Taslim and Ahmad Syukri and Paskalis Indra and Muzakkir Amir and Peter Kabo and Robert Setiadji},
  title = {Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids},
  journal = {International Journal of HIV/AIDS Prevention, Education and Behavioural Science},
  volume = {4},
  number = {1},
  pages = {5-10},
  doi = {10.11648/j.ijhpebs.20180401.12},
  url = {https://doi.org/10.11648/j.ijhpebs.20180401.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhpebs.20180401.12},
  abstract = {Background: People with Acquired Immunodeficiency Syndrome (AIDS) are at risk of developing structural and functional cardiac abnormalities that are unrelated to common cardiac risk factors (e.g. Hypertension, Diabetes Mellitus, Smoking habit). AIDS may be associated with chronic inflammation related to multiple factors related to the Human Immunodeficiency Virus (HIV) infection and its complications. Cardiac abnormality with AIDS may be subclinical and may present long before the onset of clinical heart failure symptoms. Objectives: To anticipate the risk of cardiovascular morbidity in people with AIDS. Methods: The researchers studied 52 people with AIDS in this observational cross-sectional study, which were further categorized into those with cluster of differentiation 4 (CD4) count of less than 200/mm3 and those with CD4 count of more than 200/mm3. Echocardiographic examinations were done to evaluate cardiac structural and functional values. Results: Mean age was 33 years old, predominantly male (71.2%). The group with a CD4 count of less than 200/mm3 showed higher Left Ventricular Mass Index (LVMI) values (113.08 vs. 39.99, p=0.012), a higher risk of developing diastolic dysfunction (OR 9.35, CI 95%, p=0.018) and pericardial effusion (OR 3.83, CI 95%, p=0.048). Conclusion: A CD4 count of less than 200/mm3 is associated with a higher risk of developing cardiac diastolic dysfunction and structural abnormalities.},
 year = {2018}
}

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TY  - JOUR
T1  - Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids
AU  - Farid Hidayat
AU  - Dian Pratiwi
AU  - Titus Kurnia
AU  - Taslim
AU  - Ahmad Syukri
AU  - Paskalis Indra
AU  - Muzakkir Amir
AU  - Peter Kabo
AU  - Robert Setiadji
Y1  - 2018/04/12
PY  - 2018
N1  - https://doi.org/10.11648/j.ijhpebs.20180401.12
DO  - 10.11648/j.ijhpebs.20180401.12
T2  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JF  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JO  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
SP  - 5
EP  - 10
PB  - Science Publishing Group
SN  - 2575-5765
UR  - https://doi.org/10.11648/j.ijhpebs.20180401.12
AB  - Background: People with Acquired Immunodeficiency Syndrome (AIDS) are at risk of developing structural and functional cardiac abnormalities that are unrelated to common cardiac risk factors (e.g. Hypertension, Diabetes Mellitus, Smoking habit). AIDS may be associated with chronic inflammation related to multiple factors related to the Human Immunodeficiency Virus (HIV) infection and its complications. Cardiac abnormality with AIDS may be subclinical and may present long before the onset of clinical heart failure symptoms. Objectives: To anticipate the risk of cardiovascular morbidity in people with AIDS. Methods: The researchers studied 52 people with AIDS in this observational cross-sectional study, which were further categorized into those with cluster of differentiation 4 (CD4) count of less than 200/mm3 and those with CD4 count of more than 200/mm3. Echocardiographic examinations were done to evaluate cardiac structural and functional values. Results: Mean age was 33 years old, predominantly male (71.2%). The group with a CD4 count of less than 200/mm3 showed higher Left Ventricular Mass Index (LVMI) values (113.08 vs. 39.99, p=0.012), a higher risk of developing diastolic dysfunction (OR 9.35, CI 95%, p=0.018) and pericardial effusion (OR 3.83, CI 95%, p=0.048). Conclusion: A CD4 count of less than 200/mm3 is associated with a higher risk of developing cardiac diastolic dysfunction and structural abnormalities.
VL  - 4
IS  - 1
ER  -

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Author Information

Farid Hidayat

Cardiac Centre of Wahidin Sudirohusodo General Hospital, Department of Cardiology and Vascular Disease, Medical Faculty of Hasanuddin University, Makassar, Indonesia
Dian Pratiwi

Cardiac Centre of Wahidin Sudirohusodo General Hospital, Department of Cardiology and Vascular Disease, Medical Faculty of Hasanuddin University, Makassar, Indonesia
Titus Kurnia

Cardiac Centre of Wahidin Sudirohusodo General Hospital, Department of Cardiology and Vascular Disease, Medical Faculty of Hasanuddin University, Makassar, Indonesia
Taslim

Cardiac Centre of Wahidin Sudirohusodo General Hospital, Department of Cardiology and Vascular Disease, Medical Faculty of Hasanuddin University, Makassar, Indonesia
Ahmad Syukri

Cardiac Centre of Wahidin Sudirohusodo General Hospital, Department of Cardiology and Vascular Disease, Medical Faculty of Hasanuddin University, Makassar, Indonesia
Paskalis Indra

Cardiac Centre of Wahidin Sudirohusodo General Hospital, Department of Cardiology and Vascular Disease, Medical Faculty of Hasanuddin University, Makassar, Indonesia
Muzakkir Amir

Cardiac Centre of Wahidin Sudirohusodo General Hospital, Department of Cardiology and Vascular Disease, Medical Faculty of Hasanuddin University, Makassar, Indonesia
Peter Kabo

Cardiac Centre of Wahidin Sudirohusodo General Hospital, Department of Cardiology and Vascular Disease, Medical Faculty of Hasanuddin University, Makassar, Indonesia
Robert Setiadji

Cardiac Centre of Wahidin Sudirohusodo General Hospital, Department of Cardiology and Vascular Disease, Medical Faculty of Hasanuddin University, Makassar, Indonesia

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Plain Text BibTeX RIS

APA Style

Farid Hidayat, Dian Pratiwi, Titus Kurnia, Taslim, Ahmad Syukri, et al. (2018). Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids. International Journal of HIV/AIDS Prevention, Education and Behavioural Science, 4(1), 5-10. https://doi.org/10.11648/j.ijhpebs.20180401.12

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ACS Style

Farid Hidayat; Dian Pratiwi; Titus Kurnia; Taslim; Ahmad Syukri, et al. Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids. Int. J. HIV/AIDS Prev. Educ. Behav. Sci. 2018, 4(1), 5-10. doi: 10.11648/j.ijhpebs.20180401.12

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AMA Style

Farid Hidayat, Dian Pratiwi, Titus Kurnia, Taslim, Ahmad Syukri, et al. Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids. Int J HIV/AIDS Prev Educ Behav Sci. 2018;4(1):5-10. doi: 10.11648/j.ijhpebs.20180401.12

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@article{10.11648/j.ijhpebs.20180401.12,
  author = {Farid Hidayat and Dian Pratiwi and Titus Kurnia and Taslim and Ahmad Syukri and Paskalis Indra and Muzakkir Amir and Peter Kabo and Robert Setiadji},
  title = {Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids},
  journal = {International Journal of HIV/AIDS Prevention, Education and Behavioural Science},
  volume = {4},
  number = {1},
  pages = {5-10},
  doi = {10.11648/j.ijhpebs.20180401.12},
  url = {https://doi.org/10.11648/j.ijhpebs.20180401.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhpebs.20180401.12},
  abstract = {Background: People with Acquired Immunodeficiency Syndrome (AIDS) are at risk of developing structural and functional cardiac abnormalities that are unrelated to common cardiac risk factors (e.g. Hypertension, Diabetes Mellitus, Smoking habit). AIDS may be associated with chronic inflammation related to multiple factors related to the Human Immunodeficiency Virus (HIV) infection and its complications. Cardiac abnormality with AIDS may be subclinical and may present long before the onset of clinical heart failure symptoms. Objectives: To anticipate the risk of cardiovascular morbidity in people with AIDS. Methods: The researchers studied 52 people with AIDS in this observational cross-sectional study, which were further categorized into those with cluster of differentiation 4 (CD4) count of less than 200/mm3 and those with CD4 count of more than 200/mm3. Echocardiographic examinations were done to evaluate cardiac structural and functional values. Results: Mean age was 33 years old, predominantly male (71.2%). The group with a CD4 count of less than 200/mm3 showed higher Left Ventricular Mass Index (LVMI) values (113.08 vs. 39.99, p=0.012), a higher risk of developing diastolic dysfunction (OR 9.35, CI 95%, p=0.018) and pericardial effusion (OR 3.83, CI 95%, p=0.048). Conclusion: A CD4 count of less than 200/mm3 is associated with a higher risk of developing cardiac diastolic dysfunction and structural abnormalities.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Cluster of Differentiation 4 Count and Left Ventricular Diastolic Function in Patients with Hiv - Aids
AU  - Farid Hidayat
AU  - Dian Pratiwi
AU  - Titus Kurnia
AU  - Taslim
AU  - Ahmad Syukri
AU  - Paskalis Indra
AU  - Muzakkir Amir
AU  - Peter Kabo
AU  - Robert Setiadji
Y1  - 2018/04/12
PY  - 2018
N1  - https://doi.org/10.11648/j.ijhpebs.20180401.12
DO  - 10.11648/j.ijhpebs.20180401.12
T2  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JF  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
JO  - International Journal of HIV/AIDS Prevention, Education and Behavioural Science
SP  - 5
EP  - 10
PB  - Science Publishing Group
SN  - 2575-5765
UR  - https://doi.org/10.11648/j.ijhpebs.20180401.12
AB  - Background: People with Acquired Immunodeficiency Syndrome (AIDS) are at risk of developing structural and functional cardiac abnormalities that are unrelated to common cardiac risk factors (e.g. Hypertension, Diabetes Mellitus, Smoking habit). AIDS may be associated with chronic inflammation related to multiple factors related to the Human Immunodeficiency Virus (HIV) infection and its complications. Cardiac abnormality with AIDS may be subclinical and may present long before the onset of clinical heart failure symptoms. Objectives: To anticipate the risk of cardiovascular morbidity in people with AIDS. Methods: The researchers studied 52 people with AIDS in this observational cross-sectional study, which were further categorized into those with cluster of differentiation 4 (CD4) count of less than 200/mm3 and those with CD4 count of more than 200/mm3. Echocardiographic examinations were done to evaluate cardiac structural and functional values. Results: Mean age was 33 years old, predominantly male (71.2%). The group with a CD4 count of less than 200/mm3 showed higher Left Ventricular Mass Index (LVMI) values (113.08 vs. 39.99, p=0.012), a higher risk of developing diastolic dysfunction (OR 9.35, CI 95%, p=0.018) and pericardial effusion (OR 3.83, CI 95%, p=0.048). Conclusion: A CD4 count of less than 200/mm3 is associated with a higher risk of developing cardiac diastolic dysfunction and structural abnormalities.
VL  - 4
IS  - 1
ER  -

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