Intraocular Pressure Changes After Intravitreal Bevacizumab Injection Alone or Combination of Bevacizumab and Triamcinolone Acetonide

Nour Yasser Barakat; Yusuf Suleiman; Kahtan Jalloul

doi:doi:10.11648/j.ijhnm.20200602.11

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Intraocular Pressure Changes After Intravitreal Bevacizumab Injection Alone or Combination of Bevacizumab and Triamcinolone Acetonide

Nour Yasser Barakat, Yusuf Suleiman, Kahtan Jalloul

Published in International Journal of Homeopathy & Natural Medicines (Volume 6, Issue 2)

Received: 31 July 2020 Accepted: 12 August 2020 Published: 11 December 2020

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Abstract

Aim: To evaluate intraocular pressure changes after intravitreal injection of Bevacizumab alone or in combination with Triamcinolone Acetonide. Method: Our study included 63 eyes from the ophthalmology department at Tishreen University Hospital who had vascular retinal diseases. The patients were divided into two groups according to the indication of injection. The first group was injected with bevacizumab (B) at a concentration of 2.5mg / 0.1 ml and the second group was injected with the combination treatment of Triamcinolone Acetonide at a concentration of 2mg / 0.05ml with bevacizumab (B+TA) at a concentration of 1.25mg/ 0.05ml. Intraocular pressure was monitored on the Goldman applanation tonometry and values were recorded as follows: before injection, the second injection day, a week after injection, a month after injection and after three months. Results: The mean values of the intraocular pressure mean increased from the second day of injection in the study groups (B) and (B+TA) and the mean of the IOP values before injection (13.34-13.31 mmHg) respectively, and the IOP values showed the maximum in both groups after a week of the injection (17.81-17.31 mmHg) then began to decrease after a month and three months later to (17.34-17.06mmHg) and (17.6-16.75mmHg) mercury respectively, but they remained higher than they were before the injection, and the number of injections had no effect on intraocular pressure. Conclusion: intravitreal injections with both bevacizumab alone or in combination with triamcinolone acetonide resulted in a rise in intraocular pressure, and differences in pressure values were statistically significant within the same group during the studied time periods but were not statistically significant between the two groups, and the number of injections had no effect on intraocular pressure.

Published in	International Journal of Homeopathy & Natural Medicines (Volume 6, Issue 2)
DOI	10.11648/j.ijhnm.20200602.11
Page(s)	6-14
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Bevacizumab, Triamcinolone Acetonide, Intraocular Pressure

References

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APA Style

Nour Yasser Barakat, Yusuf Suleiman, Kahtan Jalloul. (2020). Intraocular Pressure Changes After Intravitreal Bevacizumab Injection Alone or Combination of Bevacizumab and Triamcinolone Acetonide. International Journal of Homeopathy & Natural Medicines, 6(2), 6-14. https://doi.org/10.11648/j.ijhnm.20200602.11

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ACS Style

Nour Yasser Barakat; Yusuf Suleiman; Kahtan Jalloul. Intraocular Pressure Changes After Intravitreal Bevacizumab Injection Alone or Combination of Bevacizumab and Triamcinolone Acetonide. Int. J. Homeopathy Nat. Med. 2020, 6(2), 6-14. doi: 10.11648/j.ijhnm.20200602.11

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AMA Style

Nour Yasser Barakat, Yusuf Suleiman, Kahtan Jalloul. Intraocular Pressure Changes After Intravitreal Bevacizumab Injection Alone or Combination of Bevacizumab and Triamcinolone Acetonide. Int J Homeopathy Nat Med. 2020;6(2):6-14. doi: 10.11648/j.ijhnm.20200602.11

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@article{10.11648/j.ijhnm.20200602.11,
  author = {Nour Yasser Barakat and Yusuf Suleiman and Kahtan Jalloul},
  title = {Intraocular Pressure Changes After Intravitreal Bevacizumab Injection Alone or Combination of Bevacizumab and Triamcinolone Acetonide},
  journal = {International Journal of Homeopathy & Natural Medicines},
  volume = {6},
  number = {2},
  pages = {6-14},
  doi = {10.11648/j.ijhnm.20200602.11},
  url = {https://doi.org/10.11648/j.ijhnm.20200602.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhnm.20200602.11},
  abstract = {Aim: To evaluate intraocular pressure changes after intravitreal injection of Bevacizumab alone or in combination with Triamcinolone Acetonide. Method: Our study included 63 eyes from the ophthalmology department at Tishreen University Hospital who had vascular retinal diseases. The patients were divided into two groups according to the indication of injection. The first group was injected with bevacizumab (B) at a concentration of 2.5mg / 0.1 ml and the second group was injected with the combination treatment of Triamcinolone Acetonide at a concentration of 2mg / 0.05ml with bevacizumab (B+TA) at a concentration of 1.25mg/ 0.05ml. Intraocular pressure was monitored on the Goldman applanation tonometry and values were recorded as follows: before injection, the second injection day, a week after injection, a month after injection and after three months. Results: The mean values of the intraocular pressure mean increased from the second day of injection in the study groups (B) and (B+TA) and the mean of the IOP values before injection (13.34-13.31 mmHg) respectively, and the IOP values showed the maximum in both groups after a week of the injection (17.81-17.31 mmHg) then began to decrease after a month and three months later to (17.34-17.06mmHg) and (17.6-16.75mmHg) mercury respectively, but they remained higher than they were before the injection, and the number of injections had no effect on intraocular pressure. Conclusion: intravitreal injections with both bevacizumab alone or in combination with triamcinolone acetonide resulted in a rise in intraocular pressure, and differences in pressure values were statistically significant within the same group during the studied time periods but were not statistically significant between the two groups, and the number of injections had no effect on intraocular pressure.},
 year = {2020}
}

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TY  - JOUR
T1  - Intraocular Pressure Changes After Intravitreal Bevacizumab Injection Alone or Combination of Bevacizumab and Triamcinolone Acetonide
AU  - Nour Yasser Barakat
AU  - Yusuf Suleiman
AU  - Kahtan Jalloul
Y1  - 2020/12/11
PY  - 2020
N1  - https://doi.org/10.11648/j.ijhnm.20200602.11
DO  - 10.11648/j.ijhnm.20200602.11
T2  - International Journal of Homeopathy & Natural Medicines
JF  - International Journal of Homeopathy & Natural Medicines
JO  - International Journal of Homeopathy & Natural Medicines
SP  - 6
EP  - 14
PB  - Science Publishing Group
SN  - 2472-2316
UR  - https://doi.org/10.11648/j.ijhnm.20200602.11
AB  - Aim: To evaluate intraocular pressure changes after intravitreal injection of Bevacizumab alone or in combination with Triamcinolone Acetonide. Method: Our study included 63 eyes from the ophthalmology department at Tishreen University Hospital who had vascular retinal diseases. The patients were divided into two groups according to the indication of injection. The first group was injected with bevacizumab (B) at a concentration of 2.5mg / 0.1 ml and the second group was injected with the combination treatment of Triamcinolone Acetonide at a concentration of 2mg / 0.05ml with bevacizumab (B+TA) at a concentration of 1.25mg/ 0.05ml. Intraocular pressure was monitored on the Goldman applanation tonometry and values were recorded as follows: before injection, the second injection day, a week after injection, a month after injection and after three months. Results: The mean values of the intraocular pressure mean increased from the second day of injection in the study groups (B) and (B+TA) and the mean of the IOP values before injection (13.34-13.31 mmHg) respectively, and the IOP values showed the maximum in both groups after a week of the injection (17.81-17.31 mmHg) then began to decrease after a month and three months later to (17.34-17.06mmHg) and (17.6-16.75mmHg) mercury respectively, but they remained higher than they were before the injection, and the number of injections had no effect on intraocular pressure. Conclusion: intravitreal injections with both bevacizumab alone or in combination with triamcinolone acetonide resulted in a rise in intraocular pressure, and differences in pressure values were statistically significant within the same group during the studied time periods but were not statistically significant between the two groups, and the number of injections had no effect on intraocular pressure.
VL  - 6
IS  - 2
ER  -

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Author Information

Nour Yasser Barakat

Ophthalmology Department, Faculty of Medicine of Tishreen University, Lattakia, Syria
Yusuf Suleiman

Ophthalmology Department, Faculty of Medicine of Tishreen University, Lattakia, Syria
Kahtan Jalloul

Ophthalmology Department, Faculty of Medicine of Tishreen University, Lattakia, Syria

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Nour Yasser Barakat, Yusuf Suleiman, Kahtan Jalloul. (2020). Intraocular Pressure Changes After Intravitreal Bevacizumab Injection Alone or Combination of Bevacizumab and Triamcinolone Acetonide. International Journal of Homeopathy & Natural Medicines, 6(2), 6-14. https://doi.org/10.11648/j.ijhnm.20200602.11

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ACS Style

Nour Yasser Barakat; Yusuf Suleiman; Kahtan Jalloul. Intraocular Pressure Changes After Intravitreal Bevacizumab Injection Alone or Combination of Bevacizumab and Triamcinolone Acetonide. Int. J. Homeopathy Nat. Med. 2020, 6(2), 6-14. doi: 10.11648/j.ijhnm.20200602.11

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AMA Style

Nour Yasser Barakat, Yusuf Suleiman, Kahtan Jalloul. Intraocular Pressure Changes After Intravitreal Bevacizumab Injection Alone or Combination of Bevacizumab and Triamcinolone Acetonide. Int J Homeopathy Nat Med. 2020;6(2):6-14. doi: 10.11648/j.ijhnm.20200602.11

Copy | Download

@article{10.11648/j.ijhnm.20200602.11,
  author = {Nour Yasser Barakat and Yusuf Suleiman and Kahtan Jalloul},
  title = {Intraocular Pressure Changes After Intravitreal Bevacizumab Injection Alone or Combination of Bevacizumab and Triamcinolone Acetonide},
  journal = {International Journal of Homeopathy & Natural Medicines},
  volume = {6},
  number = {2},
  pages = {6-14},
  doi = {10.11648/j.ijhnm.20200602.11},
  url = {https://doi.org/10.11648/j.ijhnm.20200602.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhnm.20200602.11},
  abstract = {Aim: To evaluate intraocular pressure changes after intravitreal injection of Bevacizumab alone or in combination with Triamcinolone Acetonide. Method: Our study included 63 eyes from the ophthalmology department at Tishreen University Hospital who had vascular retinal diseases. The patients were divided into two groups according to the indication of injection. The first group was injected with bevacizumab (B) at a concentration of 2.5mg / 0.1 ml and the second group was injected with the combination treatment of Triamcinolone Acetonide at a concentration of 2mg / 0.05ml with bevacizumab (B+TA) at a concentration of 1.25mg/ 0.05ml. Intraocular pressure was monitored on the Goldman applanation tonometry and values were recorded as follows: before injection, the second injection day, a week after injection, a month after injection and after three months. Results: The mean values of the intraocular pressure mean increased from the second day of injection in the study groups (B) and (B+TA) and the mean of the IOP values before injection (13.34-13.31 mmHg) respectively, and the IOP values showed the maximum in both groups after a week of the injection (17.81-17.31 mmHg) then began to decrease after a month and three months later to (17.34-17.06mmHg) and (17.6-16.75mmHg) mercury respectively, but they remained higher than they were before the injection, and the number of injections had no effect on intraocular pressure. Conclusion: intravitreal injections with both bevacizumab alone or in combination with triamcinolone acetonide resulted in a rise in intraocular pressure, and differences in pressure values were statistically significant within the same group during the studied time periods but were not statistically significant between the two groups, and the number of injections had no effect on intraocular pressure.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Intraocular Pressure Changes After Intravitreal Bevacizumab Injection Alone or Combination of Bevacizumab and Triamcinolone Acetonide
AU  - Nour Yasser Barakat
AU  - Yusuf Suleiman
AU  - Kahtan Jalloul
Y1  - 2020/12/11
PY  - 2020
N1  - https://doi.org/10.11648/j.ijhnm.20200602.11
DO  - 10.11648/j.ijhnm.20200602.11
T2  - International Journal of Homeopathy & Natural Medicines
JF  - International Journal of Homeopathy & Natural Medicines
JO  - International Journal of Homeopathy & Natural Medicines
SP  - 6
EP  - 14
PB  - Science Publishing Group
SN  - 2472-2316
UR  - https://doi.org/10.11648/j.ijhnm.20200602.11
AB  - Aim: To evaluate intraocular pressure changes after intravitreal injection of Bevacizumab alone or in combination with Triamcinolone Acetonide. Method: Our study included 63 eyes from the ophthalmology department at Tishreen University Hospital who had vascular retinal diseases. The patients were divided into two groups according to the indication of injection. The first group was injected with bevacizumab (B) at a concentration of 2.5mg / 0.1 ml and the second group was injected with the combination treatment of Triamcinolone Acetonide at a concentration of 2mg / 0.05ml with bevacizumab (B+TA) at a concentration of 1.25mg/ 0.05ml. Intraocular pressure was monitored on the Goldman applanation tonometry and values were recorded as follows: before injection, the second injection day, a week after injection, a month after injection and after three months. Results: The mean values of the intraocular pressure mean increased from the second day of injection in the study groups (B) and (B+TA) and the mean of the IOP values before injection (13.34-13.31 mmHg) respectively, and the IOP values showed the maximum in both groups after a week of the injection (17.81-17.31 mmHg) then began to decrease after a month and three months later to (17.34-17.06mmHg) and (17.6-16.75mmHg) mercury respectively, but they remained higher than they were before the injection, and the number of injections had no effect on intraocular pressure. Conclusion: intravitreal injections with both bevacizumab alone or in combination with triamcinolone acetonide resulted in a rise in intraocular pressure, and differences in pressure values were statistically significant within the same group during the studied time periods but were not statistically significant between the two groups, and the number of injections had no effect on intraocular pressure.
VL  - 6
IS  - 2
ER  -

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