Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts <i>(Cymbopogon ciratus)</i>

Ameta Primasari; Edikin Raja Sinulingga

doi:doi:10.11648/j.ijhnm.20190501.16

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Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus)

Ameta Primasari, Edikin Raja Sinulingga

Published in International Journal of Homeopathy & Natural Medicines (Volume 5, Issue 1)

Received: 3 February 2019 Accepted: 27 May 2019 Published: 20 June 2019

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Abstract

Lemongrass is one of the plants that widely used as traditional medicine in Indonesia. Lemongrass contains bioactive substances such as flavonoids, phenolic acids and tannins which act as anti-inflammatory and antioxidants that influence the wound healing process. The aim of this study was to compare the differences in buccal and labial mucosal wound healing, and to see the effect of lemongrass extract on the process of increasing oral mucosal epithelial thickness in white rats. This research is a pure experimental design with a post test-only design with control design. This study used 21 white rats divided into 3 groups where the first group of 100% lemongrass extract, the second group of 50% lemongrass extract, and the third group as the treatment that was not treated. The results of the One-way ANOVA and Post-hoc LSD test on the buccal mucosa showed significant differences with the labial mucosa. There were no significant differences in the buccal section with the second group and the third group p = 0.74 (p <0.05). There were no significant differences in the labial section with the first and second groups, but there were significant differences with the third group p = 0.003 (p <0.05). The effect of lemongrass extract has effectiveness in accelerating healing of oral mucosal wounds in white rats. There was also an increase in the thickness of the oral mucosal epithelium after administration of lemongrass extract with concentrations of 100% and 50%. Based on the research that has been done it can be concluded that healing wounds of the buccal mucosa heal faster than labial mucosal wounds because the buccal part contains saliva which has an important role in the wound healing process.

Published in	International Journal of Homeopathy & Natural Medicines (Volume 5, Issue 1)
DOI	10.11648/j.ijhnm.20190501.16
Page(s)	36-41
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Lemongrass Extract, Wound Healing, Wound Length, Thickness of the Epithelium, Oral Mucosa, White Mice

References

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APA Style

Ameta Primasari, Edikin Raja Sinulingga. (2019). Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus). International Journal of Homeopathy & Natural Medicines, 5(1), 36-41. https://doi.org/10.11648/j.ijhnm.20190501.16

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ACS Style

Ameta Primasari; Edikin Raja Sinulingga. Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus). Int. J. Homeopathy Nat. Med. 2019, 5(1), 36-41. doi: 10.11648/j.ijhnm.20190501.16

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AMA Style

Ameta Primasari, Edikin Raja Sinulingga. Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus). Int J Homeopathy Nat Med. 2019;5(1):36-41. doi: 10.11648/j.ijhnm.20190501.16

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@article{10.11648/j.ijhnm.20190501.16,
  author = {Ameta Primasari and Edikin Raja Sinulingga},
  title = {Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus)},
  journal = {International Journal of Homeopathy & Natural Medicines},
  volume = {5},
  number = {1},
  pages = {36-41},
  doi = {10.11648/j.ijhnm.20190501.16},
  url = {https://doi.org/10.11648/j.ijhnm.20190501.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhnm.20190501.16},
  abstract = {Lemongrass is one of the plants that widely used as traditional medicine in Indonesia. Lemongrass contains bioactive substances such as flavonoids, phenolic acids and tannins which act as anti-inflammatory and antioxidants that influence the wound healing process. The aim of this study was to compare the differences in buccal and labial mucosal wound healing, and to see the effect of lemongrass extract on the process of increasing oral mucosal epithelial thickness in white rats. This research is a pure experimental design with a post test-only design with control design. This study used 21 white rats divided into 3 groups where the first group of 100% lemongrass extract, the second group of 50% lemongrass extract, and the third group as the treatment that was not treated. The results of the One-way ANOVA and Post-hoc LSD test on the buccal mucosa showed significant differences with the labial mucosa. There were no significant differences in the buccal section with the second group and the third group p = 0.74 (p <0.05). There were no significant differences in the labial section with the first and second groups, but there were significant differences with the third group p = 0.003 (p <0.05). The effect of lemongrass extract has effectiveness in accelerating healing of oral mucosal wounds in white rats. There was also an increase in the thickness of the oral mucosal epithelium after administration of lemongrass extract with concentrations of 100% and 50%. Based on the research that has been done it can be concluded that healing wounds of the buccal mucosa heal faster than labial mucosal wounds because the buccal part contains saliva which has an important role in the wound healing process.},
 year = {2019}
}

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TY  - JOUR
T1  - Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus)
AU  - Ameta Primasari
AU  - Edikin Raja Sinulingga
Y1  - 2019/06/20
PY  - 2019
N1  - https://doi.org/10.11648/j.ijhnm.20190501.16
DO  - 10.11648/j.ijhnm.20190501.16
T2  - International Journal of Homeopathy & Natural Medicines
JF  - International Journal of Homeopathy & Natural Medicines
JO  - International Journal of Homeopathy & Natural Medicines
SP  - 36
EP  - 41
PB  - Science Publishing Group
SN  - 2472-2316
UR  - https://doi.org/10.11648/j.ijhnm.20190501.16
AB  - Lemongrass is one of the plants that widely used as traditional medicine in Indonesia. Lemongrass contains bioactive substances such as flavonoids, phenolic acids and tannins which act as anti-inflammatory and antioxidants that influence the wound healing process. The aim of this study was to compare the differences in buccal and labial mucosal wound healing, and to see the effect of lemongrass extract on the process of increasing oral mucosal epithelial thickness in white rats. This research is a pure experimental design with a post test-only design with control design. This study used 21 white rats divided into 3 groups where the first group of 100% lemongrass extract, the second group of 50% lemongrass extract, and the third group as the treatment that was not treated. The results of the One-way ANOVA and Post-hoc LSD test on the buccal mucosa showed significant differences with the labial mucosa. There were no significant differences in the buccal section with the second group and the third group p = 0.74 (p <0.05). There were no significant differences in the labial section with the first and second groups, but there were significant differences with the third group p = 0.003 (p <0.05). The effect of lemongrass extract has effectiveness in accelerating healing of oral mucosal wounds in white rats. There was also an increase in the thickness of the oral mucosal epithelium after administration of lemongrass extract with concentrations of 100% and 50%. Based on the research that has been done it can be concluded that healing wounds of the buccal mucosa heal faster than labial mucosal wounds because the buccal part contains saliva which has an important role in the wound healing process.
VL  - 5
IS  - 1
ER  -

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Author Information

Ameta Primasari

Department of Oral Biology, Faculty of Dentistry, Universitas Sumatera Utara, Medan, Indonesia
Edikin Raja Sinulingga

Department of Oral Biology, Faculty of Dentistry, Universitas Sumatera Utara, Medan, Indonesia

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APA Style

Ameta Primasari, Edikin Raja Sinulingga. (2019). Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus). International Journal of Homeopathy & Natural Medicines, 5(1), 36-41. https://doi.org/10.11648/j.ijhnm.20190501.16

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ACS Style

Ameta Primasari; Edikin Raja Sinulingga. Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus). Int. J. Homeopathy Nat. Med. 2019, 5(1), 36-41. doi: 10.11648/j.ijhnm.20190501.16

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AMA Style

Ameta Primasari, Edikin Raja Sinulingga. Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus). Int J Homeopathy Nat Med. 2019;5(1):36-41. doi: 10.11648/j.ijhnm.20190501.16

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@article{10.11648/j.ijhnm.20190501.16,
  author = {Ameta Primasari and Edikin Raja Sinulingga},
  title = {Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus)},
  journal = {International Journal of Homeopathy & Natural Medicines},
  volume = {5},
  number = {1},
  pages = {36-41},
  doi = {10.11648/j.ijhnm.20190501.16},
  url = {https://doi.org/10.11648/j.ijhnm.20190501.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhnm.20190501.16},
  abstract = {Lemongrass is one of the plants that widely used as traditional medicine in Indonesia. Lemongrass contains bioactive substances such as flavonoids, phenolic acids and tannins which act as anti-inflammatory and antioxidants that influence the wound healing process. The aim of this study was to compare the differences in buccal and labial mucosal wound healing, and to see the effect of lemongrass extract on the process of increasing oral mucosal epithelial thickness in white rats. This research is a pure experimental design with a post test-only design with control design. This study used 21 white rats divided into 3 groups where the first group of 100% lemongrass extract, the second group of 50% lemongrass extract, and the third group as the treatment that was not treated. The results of the One-way ANOVA and Post-hoc LSD test on the buccal mucosa showed significant differences with the labial mucosa. There were no significant differences in the buccal section with the second group and the third group p = 0.74 (p <0.05). There were no significant differences in the labial section with the first and second groups, but there were significant differences with the third group p = 0.003 (p <0.05). The effect of lemongrass extract has effectiveness in accelerating healing of oral mucosal wounds in white rats. There was also an increase in the thickness of the oral mucosal epithelium after administration of lemongrass extract with concentrations of 100% and 50%. Based on the research that has been done it can be concluded that healing wounds of the buccal mucosa heal faster than labial mucosal wounds because the buccal part contains saliva which has an important role in the wound healing process.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - Differences of Wound Healing in the Buccal Part and Oral Mucosa Labial After Giving Lemongrass Extracts (Cymbopogon ciratus)
AU  - Ameta Primasari
AU  - Edikin Raja Sinulingga
Y1  - 2019/06/20
PY  - 2019
N1  - https://doi.org/10.11648/j.ijhnm.20190501.16
DO  - 10.11648/j.ijhnm.20190501.16
T2  - International Journal of Homeopathy & Natural Medicines
JF  - International Journal of Homeopathy & Natural Medicines
JO  - International Journal of Homeopathy & Natural Medicines
SP  - 36
EP  - 41
PB  - Science Publishing Group
SN  - 2472-2316
UR  - https://doi.org/10.11648/j.ijhnm.20190501.16
AB  - Lemongrass is one of the plants that widely used as traditional medicine in Indonesia. Lemongrass contains bioactive substances such as flavonoids, phenolic acids and tannins which act as anti-inflammatory and antioxidants that influence the wound healing process. The aim of this study was to compare the differences in buccal and labial mucosal wound healing, and to see the effect of lemongrass extract on the process of increasing oral mucosal epithelial thickness in white rats. This research is a pure experimental design with a post test-only design with control design. This study used 21 white rats divided into 3 groups where the first group of 100% lemongrass extract, the second group of 50% lemongrass extract, and the third group as the treatment that was not treated. The results of the One-way ANOVA and Post-hoc LSD test on the buccal mucosa showed significant differences with the labial mucosa. There were no significant differences in the buccal section with the second group and the third group p = 0.74 (p <0.05). There were no significant differences in the labial section with the first and second groups, but there were significant differences with the third group p = 0.003 (p <0.05). The effect of lemongrass extract has effectiveness in accelerating healing of oral mucosal wounds in white rats. There was also an increase in the thickness of the oral mucosal epithelium after administration of lemongrass extract with concentrations of 100% and 50%. Based on the research that has been done it can be concluded that healing wounds of the buccal mucosa heal faster than labial mucosal wounds because the buccal part contains saliva which has an important role in the wound healing process.
VL  - 5
IS  - 1
ER  -

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