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The Impact of Sequencing Human Genome on Genomic Food & Medicine

Received: 4 March 2021     Accepted: 30 March 2021     Published: 16 April 2021
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Abstract

This abstract describes the development of novel food and drug based on the genetic make-up individuals and their diseases. It also describes how sequencing of human genome help us design the most nutritious food for the burgeoning population of world. Regardless of race, religions or place of origin, sooner or later we all have to become vegetarians. Non-vegetarians eat meat because it contains, out of 20, eight essential amino acids in concentrated form. Genome sequencing have already identified all the essential amino acid Codons which could be spliced in the Rice, Corn or Wheat genomes. Genetic tools are now available to splice essential amino acids Codons into Rice Genome. Using the genetic tools, we have successfully spliced Beta Carotene gene into the Rice Genome to produce Golden Rice. Upon ingestion of the Golden Rice, Beta Carotene is converted to Vitamin A which prevents blindness in children. Based on the genetic make-up of the host cells, we will cut, paste and copy important genes to develop new food, new fuel, and new medicine to treat every disease known to mankind. Our future lies in Space. By 2024, we plan to land men on Mars. The inhabitants of Mars will grow genetically modified plants only. We will also discuss ethical issues based on the unintended consequences of genetic modification of our food and medicine.

Published in International Journal of Genetics and Genomics (Volume 9, Issue 1)
DOI 10.11648/j.ijgg.20210901.12
Page(s) 6-19
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Nitrogen Mustard, Aziridine, Carbamate, Glioblastoma, Walker Carcinoma, AZQ

References
[1] Watson, J. D., & Crick, F. H. C. A structure for deoxyribose nucleic acid. Nature 171, 737–738 (1953).
[2] Genome Sequencing, Nature, 409,934-941, 2001.
[3] Genetics, Nature, 409, 660-921, 2001.
[4] Genomics, Nature, 431, 931-945, 2004.
[5] Genome Sequencing, 438, 803-810, 2005.
[6] Genomics, Nature, 550, 345-353, 2017.
[7] Chlorambucil - CancerConnect News". CancerConnect News. Retrieved 2015-12-21.
[8] Ross. W. C. J, “The Chemistry of Cytotoxic Alkylating Agents” In Advances in Cancer Research by Greenstein, J. P., and Haddow, A., Academic Press, Inc., New York,, 397-449, (1953).
[9] Ross, W. C. J., “Biological Alkylating Agents” Butterworth, London, 1962.
[10] Ross, W. C. J., Journal of Chemical Society, 183, 1949.
[11] Biological Alkylating Agents, Ross, W. C. J., J. Chem. Soc., 2257 (1950).
[12] Ross, W. C. J., Mitchley, B. C. V., Ann. Rep. Brit. Empire Cancer Campn, 42, 70 (1964).
[13] Melphalan Lancet 370 (9594): 1209–18.
[14] L. M. Cobb, T. A. Connors, L. A. Elson, A. H. Khan, B. C. V. Mitchley, W. C. J. Ross and M. E. Whisson, BIOCHEMICAL PHARMACOLOGY, col. 18, pp. 1519-1527 (1969) "2,4-Dinitro-5-Ethyleneiminobenzamide (CB 1954): A Potent and Selective Inhibitor of the Growth of the Walker Carcinoma 256".
[15] A. H. Khan and W. C. J. Ross, CHEM.-BIOL INTERACTIONS, vol 1, pp. 27-47 (1969/70) "Tumour-Growth Inhibitory Nitrophenylaziridines and related compounds: Structure-Activity Relationships" PART I.
[16] A. H. Khan and W. C. J. Ross, CHEM.-BIOL INTERACTIONS, vol 4, pp. 11-22 (1971/72) "Tumour-Growth Inhibitory Nitrophenylaziridines and related compounds: Structure-Activity Relationships" PART II.
[17] A. Hameed Khan and John Driscoll, JOURNAL OF MEDICINAL CHEMISTRY, vol. 19, No. 2, pp. 313-317 (1976) "Potential Central Nervous System Antitumor Agents: Aziridinylbenzoquinones. PART I.
[18] Ed Chou, A. Hameed Khan and John Driscoll, JOURNAL OF MEDICINAL CHEMISTRY, vol. 19, pp. 1302 (1976) "Potential Central Nervous System Antitumor Agents: Aziridinylbenzoquinones. PART II.
[19] "Aziridinyl Quinone: Anti-transplanted Tumor Agents". UNITES STATES PATENT # 4,146,622, (March 27, 1979) Investors: John S. Driscoll; A. Hameed Khan; Feng-e-Chou, NIH, Maryland, USA Additional Information is available at Facebook.com/hameed.khan 7773.
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  • APA Style

    Hameed Khan. (2021). The Impact of Sequencing Human Genome on Genomic Food & Medicine. International Journal of Genetics and Genomics, 9(1), 6-19. https://doi.org/10.11648/j.ijgg.20210901.12

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    ACS Style

    Hameed Khan. The Impact of Sequencing Human Genome on Genomic Food & Medicine. Int. J. Genet. Genomics 2021, 9(1), 6-19. doi: 10.11648/j.ijgg.20210901.12

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    AMA Style

    Hameed Khan. The Impact of Sequencing Human Genome on Genomic Food & Medicine. Int J Genet Genomics. 2021;9(1):6-19. doi: 10.11648/j.ijgg.20210901.12

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  • @article{10.11648/j.ijgg.20210901.12,
      author = {Hameed Khan},
      title = {The Impact of Sequencing Human Genome on Genomic Food & Medicine},
      journal = {International Journal of Genetics and Genomics},
      volume = {9},
      number = {1},
      pages = {6-19},
      doi = {10.11648/j.ijgg.20210901.12},
      url = {https://doi.org/10.11648/j.ijgg.20210901.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijgg.20210901.12},
      abstract = {This abstract describes the development of novel food and drug based on the genetic make-up individuals and their diseases. It also describes how sequencing of human genome help us design the most nutritious food for the burgeoning population of world. Regardless of race, religions or place of origin, sooner or later we all have to become vegetarians. Non-vegetarians eat meat because it contains, out of 20, eight essential amino acids in concentrated form. Genome sequencing have already identified all the essential amino acid Codons which could be spliced in the Rice, Corn or Wheat genomes. Genetic tools are now available to splice essential amino acids Codons into Rice Genome. Using the genetic tools, we have successfully spliced Beta Carotene gene into the Rice Genome to produce Golden Rice. Upon ingestion of the Golden Rice, Beta Carotene is converted to Vitamin A which prevents blindness in children. Based on the genetic make-up of the host cells, we will cut, paste and copy important genes to develop new food, new fuel, and new medicine to treat every disease known to mankind. Our future lies in Space. By 2024, we plan to land men on Mars. The inhabitants of Mars will grow genetically modified plants only. We will also discuss ethical issues based on the unintended consequences of genetic modification of our food and medicine.},
     year = {2021}
    }
    

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Author Information
  • Department of Genetics & Robotics, NCMRR (National Center for Medical Rehabilitation Research), National Institutes of Health (NIH), Bethesda, Maryland, USA

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