| Peer-Reviewed

Frequency of ABO, Rh Blood Group Alleles Among Oromo, Amhara and Wolayita Ethnic Group Students in Robe Secondary, Preparatory and Zeybela Primary School, Bale, Ethiopia

Received: 21 February 2017     Accepted: 13 March 2017     Published: 1 June 2017
Views:       Downloads:
Abstract

The ABO and Rh blood groups are the most important blood groups despite the long list of several other blood groups discovered so far. The ABO and Rh blood groups varies worldwide and are not found in equal numbers even among ethnic groups. Therefore, this study aimed at having information on the frequencies of alleles, phenotypes and genotypes of ABO and Rh D blood groups among the major ethnic groups of Robe Secondary and Preparatory and Zebela Primary school students in Oromia region, Bale zone, Robe town. A total of 600 students were purposively selected and divided into 3 major ethnic groups i.e., Oromo, Amahara, and Wolayita, each consists of 200 students. Purposively sampled students were obtained on the basis of their willingness to participate by filling all their profile and signed on the consent agreement format. Differences in allelic, phenotypic and genotypic frequencies of the (ABO) and Rh D blood groups among the three ethnic groups of the students were observed. Blood group O and Rh (D) positive has highest allelic and phenotypic frequencies while blood group AB and Rh (D) negative has the lowest allelic and phenotypic frequencies in all the three ethnic groups. However, apart from the importance of ABO and Rh blood groups in blood transfusion practice, it is therefore imperative to have information on the distribution of these blood groups in any population group that comprise different ethnic groups.

Published in International Journal of Genetics and Genomics (Volume 5, Issue 2)
DOI 10.11648/j.ijgg.20170502.11
Page(s) 19-26
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Allele, Ethnic Group, Frequency, Genotypes, Phenotypes, ABO Blood Group, Rh Blood Group

References
[1] Adeyemo, A. F and O. B, Soboyejo., 2006. Frequency distribution of ABO, RH blood groups and blood genotypes among the biology and genetics students of university of Lagos, Nigeria Afri J of biotechnol 5 (22). 2062-2065.
[2] Ahmed, S. G., U. A. Ibrahim and A. W. Hassan (2007). Adequacy and pattern of blood donations in northeast Nigeria: The implications for blood safety. Ann. Trop. Med. Parasitol., 101: 725-731. PMID: 18028734.
[3] Ahmed, S. G. and S. O. Obi (1998). The incidence of ABO and rhesus-D blood groups in northeast Nigeria. Nig. J. Med., 7: 68-70.
[4] Ahmed, S. G., B. A. Umar, A. T. Saidu and B. Jolayemi (2004). Pattern and clinical significance ofABO and rhesus-D red cell phenotypes among blood donors Birnin kudu,Nigeria. Borno. med. J., 1: 1-6.
[5] Akhigbe, R. E., S. F. Ige, A. O. Afolabi, O. M. Azeez, G. J. Adegunlola and J. O. Bamidele (2009). Prevalence of haemoglobin variants ABO and rhesus blood groups in Ladoke Akintola University of Technology, Ogbomoso, Nigeria. Trends Med. Res., 4: 24-29. DOI: 10.3923/tmr.2009.24.29.
[6] Amundadottir L,Kraft P, Stolzenberg-Solomon RZ, Fuchs CS, Petersen GM, Arslan A. A etal. (2009). Genome-Wide association studies identifies variants in the ABO locus associated with susuceptibility to pancreatic cancer. Nature Genetics. 2009; 41(9):986-90.
[7] Bakare A. A., M. A. Azeez., and J. O Agbolade., 2006 Gene frequencies of ABO and rhesus blood groups and haemoglobin Variants in Ogbomosho. South –West Nigeria. Afr. J. Biotechnology., 5:224-229.
[8] Bhasin MK, Chahal SMS 1995. A Laboratory Manual for Human Blood Analysis.Delhi: Kamla-RajEnterperises.
[9] Cartron,J. P. (1994). Defining the Rh blood group antigens. Biochemistry and molecular genet.cs. Blood Rev., 8:199-212.
[10] Chakraborty DP, Prediction accuracy of a sample size estimation method for ROC Students, Academic Radiology, diol:10.1016fj.acra 2010.01.007.
[11] CSAE, 2007 Population and housing census Atlas of Ethiopia.
[12] Daniel, H, L, and A. G, clark, 2007. Principle of population Genetics. 4th. Sinauer. Associates. Sunderland, Massachusetts. P633.
[13] Eastlund, T., The histo-blood groupsystem ABO and tissue transplantation. Transfusion 1998; 38: 975-988.
[14] Garratty, G., W.Dzink., PD. Issitt., DM., Lublin Reid., and T. Zelinski,. Terminology for blood group antigens and genes-historical origins and guideline in the new millennium. Transfusion 2000; 40: 477-489.
[15] Greenwell, P.(1997): Blood group antigens: Molecules seeking a function. Glycoconjugate J. 14: 159-173.
[16] Griffiths, A. F, S. R, Wessler, R. C, Leewontin, and S. B. Carroll., 2008. Introduction to Genetic Analysis. 9th edition. W. H. freeman and company. New York. P838.
[17] Hussain A, Shiekh SA, Haider M, Rasheed T, Malik MR. Frequency of ABO and Rh blood groups in population of Balouchistan (Pakistan). PakArmed ForcesMed J 2001;51:22–6.
[18] Khattak, I. D., T. M. Khan., P. Syed., A. M. Shah., S. T. Khattak., and A. Ali., (2008). Frequency of ABO and rhesus blood group in swat, Pakistan j Ayub Med Coll Abbottabad 2008;20(4).
[19] Kulkarni, A. G., B. Peter, R. Ibazebo, B. Dash and A. F. Fleming, (1985). The ABO and Rhesus groups in the North of Nigeria. Ann. Trop. Med. Parasitol., 79: 83-88.
[20] L. Beckman, (2008). A contribution to a physical Anthropology and population genetics: Racial and Ethine Distribution of ABO blood types, Blood Book.com.
[21] (Mc Clelland DBL. Hand book of transfusion medicine, 3rded.The stationery office, London, 2001).
[22] Meade, T. W., J. A. Cooper, Y. Stirling, D, J. Howarth, V. Ruddock, $ G. J. Miller 1994. Factor VIII. ABO blood group and the incidence of ischemic heart disease. Br J Haemat. 88:601—7.
[23] Njoku OU, IC Ononogbu, EO Alumunan, I Nwanjoh (1996). Serum lipids, ABO blood group and sickle cell trait. Ind. J. Physiol. Pharmacol. 40(2): 171 – 174.
[24] Omotade, O. O., A. A. Adeyemo., C. M. Kayode., S. L. falade., and S. Ikpeme, 1999. Gene frequencies of ABO and Rh (D) blood group alleles in a healthy infect population in Ibadan, Nigeria. West Afr. J. Med.18 (4):294-297.
[25] Salmon D, M Godlier, L Halle, P Lemonnier, JL Lorry, P Rouger, J Ruffie, C Salmon (1988). Blood groups in Papua NewGuinea Eastern Highlands, Gene Geogr. 2: 89 – 98.
[26] Srikumari, C.R., J, Rajanikumari.,$ T.V. Rao.1987.Acuity of selective mechanisms operating on ABO. Rh (D) and MN blood groups Am I phy anthrop 72(1): 117-121.
[27] Thangaraj K, CR Srikumari, A Ramesh (1992). The genetic composition of an endogenous Adi – Dravidar population ofTami – Nadu. Gene Geogr. 6: 27 – 30.
[28] Yan, L., Zhu, F., Fu Q. and He J. (2005).ABO, Rh, MNS, Duffy, Kidd, Yt, scianna, and colton blood group systems in indigenous Chinese. Immunohematology, 21:10-14.
[29] Yousaf, M., Yousaf, N and Zahid, A. Pattern of ABOand Rh (D) blood groups distribution in BahawalpurDivision. Pak. J. Med. Res. 1988;27(1):40-41.
Cite This Article
  • APA Style

    Nigusu Girma, Yohannes Petros. (2017). Frequency of ABO, Rh Blood Group Alleles Among Oromo, Amhara and Wolayita Ethnic Group Students in Robe Secondary, Preparatory and Zeybela Primary School, Bale, Ethiopia. International Journal of Genetics and Genomics, 5(2), 19-26. https://doi.org/10.11648/j.ijgg.20170502.11

    Copy | Download

    ACS Style

    Nigusu Girma; Yohannes Petros. Frequency of ABO, Rh Blood Group Alleles Among Oromo, Amhara and Wolayita Ethnic Group Students in Robe Secondary, Preparatory and Zeybela Primary School, Bale, Ethiopia. Int. J. Genet. Genomics 2017, 5(2), 19-26. doi: 10.11648/j.ijgg.20170502.11

    Copy | Download

    AMA Style

    Nigusu Girma, Yohannes Petros. Frequency of ABO, Rh Blood Group Alleles Among Oromo, Amhara and Wolayita Ethnic Group Students in Robe Secondary, Preparatory and Zeybela Primary School, Bale, Ethiopia. Int J Genet Genomics. 2017;5(2):19-26. doi: 10.11648/j.ijgg.20170502.11

    Copy | Download

  • @article{10.11648/j.ijgg.20170502.11,
      author = {Nigusu Girma and Yohannes Petros},
      title = {Frequency of ABO, Rh Blood Group Alleles Among Oromo, Amhara and Wolayita Ethnic Group Students in Robe Secondary, Preparatory and Zeybela Primary School, Bale, Ethiopia},
      journal = {International Journal of Genetics and Genomics},
      volume = {5},
      number = {2},
      pages = {19-26},
      doi = {10.11648/j.ijgg.20170502.11},
      url = {https://doi.org/10.11648/j.ijgg.20170502.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijgg.20170502.11},
      abstract = {The ABO and Rh blood groups are the most important blood groups despite the long list of several other blood groups discovered so far. The ABO and Rh blood groups varies worldwide and are not found in equal numbers even among ethnic groups. Therefore, this study aimed at having information on the frequencies of alleles, phenotypes and genotypes of ABO and Rh D blood groups among the major ethnic groups of Robe Secondary and Preparatory and Zebela Primary school students in Oromia region, Bale zone, Robe town. A total of 600 students were purposively selected and divided into 3 major ethnic groups i.e., Oromo, Amahara, and Wolayita, each consists of 200 students. Purposively sampled students were obtained on the basis of their willingness to participate by filling all their profile and signed on the consent agreement format. Differences in allelic, phenotypic and genotypic frequencies of the (ABO) and Rh D blood groups among the three ethnic groups of the students were observed. Blood group O and Rh (D) positive has highest allelic and phenotypic frequencies while blood group AB and Rh (D) negative has the lowest allelic and phenotypic frequencies in all the three ethnic groups. However, apart from the importance of ABO and Rh blood groups in blood transfusion practice, it is therefore imperative to have information on the distribution of these blood groups in any population group that comprise different ethnic groups.},
     year = {2017}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Frequency of ABO, Rh Blood Group Alleles Among Oromo, Amhara and Wolayita Ethnic Group Students in Robe Secondary, Preparatory and Zeybela Primary School, Bale, Ethiopia
    AU  - Nigusu Girma
    AU  - Yohannes Petros
    Y1  - 2017/06/01
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ijgg.20170502.11
    DO  - 10.11648/j.ijgg.20170502.11
    T2  - International Journal of Genetics and Genomics
    JF  - International Journal of Genetics and Genomics
    JO  - International Journal of Genetics and Genomics
    SP  - 19
    EP  - 26
    PB  - Science Publishing Group
    SN  - 2376-7359
    UR  - https://doi.org/10.11648/j.ijgg.20170502.11
    AB  - The ABO and Rh blood groups are the most important blood groups despite the long list of several other blood groups discovered so far. The ABO and Rh blood groups varies worldwide and are not found in equal numbers even among ethnic groups. Therefore, this study aimed at having information on the frequencies of alleles, phenotypes and genotypes of ABO and Rh D blood groups among the major ethnic groups of Robe Secondary and Preparatory and Zebela Primary school students in Oromia region, Bale zone, Robe town. A total of 600 students were purposively selected and divided into 3 major ethnic groups i.e., Oromo, Amahara, and Wolayita, each consists of 200 students. Purposively sampled students were obtained on the basis of their willingness to participate by filling all their profile and signed on the consent agreement format. Differences in allelic, phenotypic and genotypic frequencies of the (ABO) and Rh D blood groups among the three ethnic groups of the students were observed. Blood group O and Rh (D) positive has highest allelic and phenotypic frequencies while blood group AB and Rh (D) negative has the lowest allelic and phenotypic frequencies in all the three ethnic groups. However, apart from the importance of ABO and Rh blood groups in blood transfusion practice, it is therefore imperative to have information on the distribution of these blood groups in any population group that comprise different ethnic groups.
    VL  - 5
    IS  - 2
    ER  - 

    Copy | Download

Author Information
  • Ethiopian Biodiversity Institute, Goba Biodiversity Center, Goba, Ethiopia

  • Department of Biology, College of Natural and Computational Science, Haramaya University, Haramaya, Ethiopia

  • Sections