Research Article | | Peer-Reviewed

Review on the Effect of Aflatoxin on the Safety and Quality of Milk Production in Dairy Farms of Ethiopia

Received: 12 November 2025     Accepted: 21 November 2025     Published: 26 December 2025
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Abstract

Aflatoxins are a group of highly toxic and carcinogenic secondary metabolites predominantly produced by the fungi Aspergillus flavus, Aspergillus parasiticus, and occasionally Aspergillus nomius. These fungi proliferate under warm, humid and tropical conditions, making certain regions, including Ethiopia, particularly susceptible to aflatoxin contamination. Factors such as fluctuating climatic conditions, traditional post-harvest handling and inadequate feed storage systems exacerbate the risk of contamination. When lactating cows consume aflatoxin-contaminated feed, primarily containing Aflatoxin B1 (AFB1), it is metabolized in the liver into Aflatoxin M1 (AFM1), which is subsequently excreted in milk. This metabolite is heat stable and can persist even after standard milk processing methods such as pasteurization or ultrahigh temperature (UHT) treatment, posing serious food safety concerns. AFM1-contaminated milk is particularly hazardous to vulnerable populations, including infants, young children and pregnant women, as it can impair growth, compromise immunity and increases the risk of liver cancer over prolonged exposure. Effective mitigation strategies require a multifaceted approach. These include adopting proper feed management techniques, such as drying crops to safe moisture levels, using hygienic and elevated storage facilities, employing bio control methods to reduce fungal growth and routinely monitoring aflatoxin levels in both feed and milk. Awareness campaigns and farmer training programs are also critical to encourage compliance with best practices. In Ethiopia, strengthening regulatory frameworks and implementing systematic surveillance of aflatoxins in dairy production can significantly reduce public health risks, enhance milk safety and support the sustainable development of the dairy sector.

Published in International Journal of Food Science and Biotechnology (Volume 10, Issue 4)
DOI 10.11648/j.ijfsb.20251004.12
Page(s) 93-97
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Aflatoxin, Milk Safety, Dairy Feed Contamination, Ethiopia, Food Safety, Public Health, Storage Practice

References
[1] Alemu, T., Dejene, G., & Abebe, R. (2019). Assessment of aflatoxin contamination in dairy feeds and milk in central Ethiopia. Ethiopian Journal of Veterinary Science, 13(2), 45–56.
[2] Codex Alimentarius. (2020). Code of Practice for the Prevention and Reduction of Mycotoxin Contamination in Cereals. Rome: FAO/WHO.
[3] EFDA. (2022). Draft National Standards on Aflatoxin Maximum Limits in Food and Feed. Ethiopian Food and Drug Authority, Addis Ababa.
[4] EFSA (European Food Safety Authority). (2020). Risk assessment of aflatoxins in food and feed. EFSA Journal, 18(3).
[5] FAO. (2019). Mycotoxin Control in Food: A Guide for Developing Countries. Rome: FAO.
[6] Fikadu, J., Tamir, B., Galmessa, U., & Effa, K. (2022). Feed quality and prevalence of aflatoxin contamination in dairy feed and milk in Oromia Special Zone. Asian Journal of Dairy and Food Research, 41(1), 8–14.
[7] Gizachew, D., Szonyi, B., Tegegne, A., Hanson, J., & Grace, D. (2016). Aflatoxin contamination of milk and dairy feeds in the Greater Addis Ababa milk shed, Ethiopia. Food Control, 59, 773–779.
[8] Hussein, H. S., & Brasel, J. M. (2001). Toxicity, metabolism, and impact of mycotoxins on humans and animals. Toxicology, 167(2), 101–134.
[9] ILRI. (2016). Aflatoxin contamination of milk and dairy feeds in the Greater Addis Ababa milk shed, Ethiopia. Nairobi: International Livestock Research Institute.
[10] Ministry of Agriculture (MoA). (2021). Ethiopia Livestock Master Plan Progress Report. Addis Ababa.
[11] Phillips, T. D., Afriyie-Gyawu, E., Williams, J., et al. (2008). Reducing aflatoxin exposure through interventional strategies in Africa. Journal of Toxicology: Toxin Reviews, 27(1), 91–97.
[12] Sleshi, M. (2018). Status of Aflatoxin M1 and Bacteriological Quality of Pasteurized Milk in Addis Ababa. MSc Thesis, Addis Ababa University.
[13] Wild, C. P., & Gong, Y. Y. (2010). Mycotoxins and human disease: A largely ignored global health issue. Carcinogenesis, 31(1), 71–82.
[14] Williams, J. H., Phillips, T. D., Jolly, P. E., et al. (2004). Human aflatoxicosis in developing countries: a review. The American Journal of Clinical Nutrition, 80(5), 1106–1122.
[15] Zebib, H., Abate D., & Woldegiorgis, A. Z. (2023). Exposure and health risk assessment of aflatoxin M1 in raw milk and cottage cheese in Ethiopia. Foods, 12(4), 817.
Cite This Article
  • APA Style

    Woldamichael, T. T. (2025). Review on the Effect of Aflatoxin on the Safety and Quality of Milk Production in Dairy Farms of Ethiopia. International Journal of Food Science and Biotechnology, 10(4), 93-97. https://doi.org/10.11648/j.ijfsb.20251004.12

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    ACS Style

    Woldamichael, T. T. Review on the Effect of Aflatoxin on the Safety and Quality of Milk Production in Dairy Farms of Ethiopia. Int. J. Food Sci. Biotechnol. 2025, 10(4), 93-97. doi: 10.11648/j.ijfsb.20251004.12

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    AMA Style

    Woldamichael TT. Review on the Effect of Aflatoxin on the Safety and Quality of Milk Production in Dairy Farms of Ethiopia. Int J Food Sci Biotechnol. 2025;10(4):93-97. doi: 10.11648/j.ijfsb.20251004.12

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  • @article{10.11648/j.ijfsb.20251004.12,
      author = {Tegegn Teshome Woldamichael},
      title = {Review on the Effect of Aflatoxin on the Safety and Quality of Milk Production in Dairy Farms of Ethiopia},
      journal = {International Journal of Food Science and Biotechnology},
      volume = {10},
      number = {4},
      pages = {93-97},
      doi = {10.11648/j.ijfsb.20251004.12},
      url = {https://doi.org/10.11648/j.ijfsb.20251004.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijfsb.20251004.12},
      abstract = {Aflatoxins are a group of highly toxic and carcinogenic secondary metabolites predominantly produced by the fungi Aspergillus flavus, Aspergillus parasiticus, and occasionally Aspergillus nomius. These fungi proliferate under warm, humid and tropical conditions, making certain regions, including Ethiopia, particularly susceptible to aflatoxin contamination. Factors such as fluctuating climatic conditions, traditional post-harvest handling and inadequate feed storage systems exacerbate the risk of contamination. When lactating cows consume aflatoxin-contaminated feed, primarily containing Aflatoxin B1 (AFB1), it is metabolized in the liver into Aflatoxin M1 (AFM1), which is subsequently excreted in milk. This metabolite is heat stable and can persist even after standard milk processing methods such as pasteurization or ultrahigh temperature (UHT) treatment, posing serious food safety concerns. AFM1-contaminated milk is particularly hazardous to vulnerable populations, including infants, young children and pregnant women, as it can impair growth, compromise immunity and increases the risk of liver cancer over prolonged exposure. Effective mitigation strategies require a multifaceted approach. These include adopting proper feed management techniques, such as drying crops to safe moisture levels, using hygienic and elevated storage facilities, employing bio control methods to reduce fungal growth and routinely monitoring aflatoxin levels in both feed and milk. Awareness campaigns and farmer training programs are also critical to encourage compliance with best practices. In Ethiopia, strengthening regulatory frameworks and implementing systematic surveillance of aflatoxins in dairy production can significantly reduce public health risks, enhance milk safety and support the sustainable development of the dairy sector.},
     year = {2025}
    }
    

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Author Information
  • Ethiopian Agricultural Authority Department of Milk and Honey Health Safety Quality Regulatory, Addis Ababa, Ethiopia

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