Withania somnifera (Ashwagandha) root extract and their active metabolites possess a broad range of pharmacological activities. The current study aimed to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing) on the physical, spectroscopic, and thermal properties of ashwagandha root extract using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Ashwagandha root extract was divided into two parts – one part was control without any and another part was treated with The Trivedi Effect® - Energy of Consciousness Healing Treatment remotely by eighteen renowned Biofield Energy Healers and defined as The Trivedi Effect® treated sample. The PXRD analysis exhibited that both the treated and control samples were amorphous in nature. The particle sizes at d10, d50, and d90 values of the treated sample were significantly decreased by 12.23%, 10.97%, and 1.25%, respectively with respect to the control sample. The surface area analysis revealed that the surface area of the treated sample was significantly increased by 14.29% as compared to the control sample. The FT-IR analysis indicated the alteration of the force constant for the functional groups of the treated sample in comparison to the control sample. The UV-vis analysis revealed that the wavelength for the maximum absorbance of the control and treated samples were at 205.8 and 206.0 nm, respectively. The TGA analysis revealed that the total weight loss was decreased by 0.70% in the treated sample as compared to the control sample. This indicated that the treated sample was thermally more stable as compared to the control sample. The DSC analysis indicated that the melting point of the treated sample (190.48°C) was decreased by 4.91% than the control sample (203.45°C). The latent heat of fusion of the treated (4.94 J/g) sample was significantly decreased by 42.96% compared with the control (8.66 J/g) sample. The current findings suggest that The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing) might have the astounding capacity to enhance the solubility, absorption, dissolution, and finally, bioavailability of ashwagandha root extract in various form of pharmaceutical and nutraceutical formulation by modifying its particle size and surface area. Thus, the treated ashwagandha root extract might provide better therapeutic response against against inflammatory diseases, immunological disorders, stress, arthritis, cancer, diabetes, sexual disorders, aging and other chronic infections.
Published in | International Journal of Food Science and Biotechnology (Volume 2, Issue 1) |
DOI | 10.11648/j.ijfsb.20170201.12 |
Page(s) | 6-15 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2017. Published by Science Publishing Group |
Biofield Energy Healing Treatment, Biofield Energy Healers, Consciousness Energy Healing, The Trivedi Effect®, Withania somnifera, PXRD, Particle Size, TGA, DSC
[1] | Kesarwani K, Gupta R (2013) Bioavailability enhancers of herbal origin: An overview. Asian Pac J Trop Biomed 3: 253-266. |
[2] | Singh N, Bhalla M, Jager P, Gilca M (2011) An overview on ashwagandha: A rasayana (rejuvenator) of ayurveda. Afr J Tradit Complement Altern Med 8: 208-213. |
[3] | Alam N, Hossain M, Mottalib MA, Sulaiman SA, Gan SH, Khalil MI (2012) Methanolic extracts of Withania somnifera leaves, fruits and roots possess antioxidant properties and antibacterial activities. BMC Complement Altern Med 12: 175. |
[4] | Parihar P, Shetty R, Ghafourifar P, Parihar MS (2016) Increase in oxidative stress and mitochondrial impairment in hypothalamus of streptozotocin treated diabetic rat: Antioxidative effect of Withania somnifera. Cell Mol Biol (Noisy-le-grand) 62: 73-83. |
[5] | Choudhary B, Shetty A, Langade DG (2015) Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults. Ayu. 36: 63-68. |
[6] | Halder B, Singh S, Thakur SS (2015) Withania somnifera root extract has potent cytotoxic effect against human malignant melanoma cells. PLoS One 10: e0137498. |
[7] | Verma SK, Kumar A (2011) Therapeutic uses of Withania somnifera (ashwagandha) with a note on withanolides and its pharmacological actions. Asian J Pharm Clin Res 4: 1-4. |
[8] | Shah N, Singh R, Sarangi U, Saxena N, Chaudhary A, Kaur G, Kaul SC, Wadhwa R (2015) Combinations of Ashwagandha leaf extracts protect brain-derived cells against oxidative stress and induce differentiation. PLoS One 10: e0120554. |
[9] | Al-Awthan YS, Hezabr SM, Al-Zubairi AM, Al-Hemiri FA (2014) Effects of aqueous extract of Withania somnifera on some liver biochemical and histopathological parameters in male guinea pigs. Pak J Biol Sci 17: 504-510. |
[10] | Nema R, Jain P, Khare S, Pradhan A, Gupta A, Singh D (2012) Study of Withania somnifera with the spatial reference of phytochemical, FTIR and flavonoids quantification. Int J Pharm Life Sci 3. 1530-1532. |
[11] | Kumar V, Dey A, Hadimani MB, Marcović T, Emerald M (2015) Chemistry and pharmacology of Withania somnifera: An update. Tang (Humanitas Medicine) 5: e1. |
[12] | Misra L, Mishra P, Pandey A, Sangwan RS, Sangwan NS, Tuli R (2008) Withanolides from Withania somnifera roots. Phytochemistry 69: 1000-1004. |
[13] | Lala P, Misra L, Sangwana RS, Tuli R (2006) New withanolides from fresh berries of Withania somnifera Z. Naturforsch 61b: 1143-1147. |
[14] | Zhao J, Nakamura N, Hattori M, Kuboyama T, Tohda C, Komatsu K (2002) Withanolide derivatives from the roots of Withania somnifera and their neurite outgrowth activities. Chem Pharm Bull 50. 760-765. |
[15] | Budhiraja RD, Krishan P, Sudhir S (2000) Biological activity of withanolides. J Sci Ind Res 59: 904-911. |
[16] | Baitharu I, Jain V, Deep SN, Shroff S, Sahu JK, Naik PK, Ilavazhagan G (2014) Withanolide A prevents neurodegeneration by modulating hippocampal glutathione biosynthesis during hypoxia. PLoS One 9. e105311. |
[17] | Sangwan NS, Sabir F, Mishra S, Bansal S, Sangwan RS (2014) Withanolides from Withania somnifera Dunal: Development of cellular technology and their production. Recent Pat Biotechnol 8: 25-35. |
[18] | Ku SK, Bae JS (2014) Antiplatelet, anticoagulant, and profibrinolytic activities of withaferin A. Vascul Pharmacol 60: 120-126. |
[19] | Gao S, Li H, Zhou XQ, You JB, Tu DN, Xia G, Jiang JX, Xin C (2015) Withaferin A attenuates lipopolysaccharide-induced acute lung injury in neonatal rats. Cell Mol Biol (Noisy-le-grand) 61: 102-106. |
[20] | Stenger VJ (1999) Bioenergetic fields. Sci Rev Alternative Med 3. |
[21] | Rogers, M (1989) "Nursing: A Science of Unitary Human Beings." In J. P. Riehl-Sisca (ed.) Conceptual Models for Nursing Practice.3rd Edn. Norwark: Appleton & Lange. |
[22] | Rubik B (2002) The biofield hypothesis: Its biophysical basis and role in medicine. J Altern Complement Med 8: 703-717. |
[23] | Nelson LA, Schwartz GE (2005) Human biofield and intention detection: Individual differences. J Altern Complement Med 11: 93-101. |
[24] | Nemeth L (2008) Energy and biofield therapies in practice. Beginnings. Summer 28. 4-5. |
[25] | Koithan M (2009) Introducing complementary and alternative therapies. J Nurse Pract 5: 18-20. |
[26] | Trivedi MK, Patil S, Shettigar H, Mondal SC, Jana S (2015) The potential impact of biofield treatment on human brain tumor cells: A time-lapse video microscopy. J Integr Oncol 4. 141. |
[27] | Trivedi MK, Branton A, Trivedi D, Shettigar H, Nayak G, Gangwar M, Jana S (2015) Antibiogram typing of biofield treated multidrug resistant strains of Staphylococcus species. American Journal of Life Sciences 3: 369-374. |
[28] | Trivedi MK, Branton A, Trivedi D, Shettigar H, Nayak G, Mondal SC, Jana S (2015) Antibiogram, biochemical reactions and genotyping characterization of biofield treated Staphylococcus aureus. American Journal of BioScience 3. 212-220. |
[29] | Trivedi MK, Branton A, Trivedi D, Nayak G, Gangwar M, Jana S (2015) Assessment of antibiogram of biofield energy treated Serratia marcescens. European Journal of Preventive Medicine 3. 201-208. |
[30] | Trivedi MK, Patil S, Shettigar H, Bairwa K, Jana S (2015) Effect of biofield treatment on phenotypic and genotypic characteristic of Provindencia rettgeri. Mol Biol 4. 129. |
[31] | Trivedi MK, Branton A, Trivedi D, Nayak G, Gangwar M, Jana S (2015) Bacterial identification using 16S rDNA gene sequencing and antibiogram analysis on biofield treated pseudomonas fluorescens. Clin Med Biochemistry Open Access 1: 101. |
[32] | Trivedi MK, Branton A, Trivedi D, Nayak G, Gangwar M, Jana S (2015) Antibiogram, biochemical reactions, and genotypic pattern of biofield treated Pseudomonas aeruginosa. J Trop Dis 4: 181. |
[33] | Trivedi MK, Branton A, Trivedi D, Nayak G, Mondal SC, Jana S (2015) Biochemical differentiation and molecular characterization of biofield treated Vibrio parahaemolyticus. American Journal of Clinical and Experimental Medicine 3. 260-267. |
[34] | Trivedi MK, Tallapragada RM (2008) A transcendental to changing metal powder characteristics. Metal Powder Report 63: 22-38. |
[35] | Dabhade VV, Tallapragada RMR, Trivedi MK (2009) Effect of external energy on the atomic, crystalline, and powder characteristics of antimony and bismuth powders. Bull Mater Sci 32. 471-479. |
[36] | Trivedi MK, Patil S, Tallapragada RM (2013) Effect of bio field treatment on the physical and thermal characteristics of vanadium pentoxide powders. J Material Sci Eng S 11: 001. |
[37] | Trivedi MK, Patil S, Shettigar H, Bairwa K, Jana S (2015) Spectroscopic characterization of chloramphenicol and tetracycline: An impact of biofield. Pharm Anal Acta 6. 395. |
[38] | Trivedi MK, Patil S, Shettigar H, Bairwa K, Jana S (2015) Spectroscopic characterization of biofield treated metronidazole and tinidazole. Med chem 5: 340-344. |
[39] | Trivedi MK, Mohan R, Branton A, Trivedi D, Nayak G, Latiyal O, Jana S (2015) Evaluation of biofield energy treatment on physical and thermal characteristics of selenium powder. Journal of Food and Nutrition Sciences 3: 223-228. |
[40] | Trivedi MK, Nayak G, Patil S, Tallapragada RM, Jana S, Mishra RK (2015) Bio-field treatment: An effective strategy to improve the quality of beef extract and meat infusion powder. J Nutr Food Sci 5. 389. |
[41] | Trivedi MK, Branton A, Trivedi D, Nayak G, Singh R, Jana S (2015) Evaluation of physical, thermal and spectroscopic properties of biofield treated p-hydroxyacetophenone. Nat Prod Chem Res 3: 190. |
[42] | Trivedi MK, Branton A, Trivedi D, Nayak G, Panda P, Jana S (2016) Gas chromatography-mass spectrometric analysis of isotopic abundance of 13C, 2H, and 18O in biofield energy treated p-tertiary butylphenol (PTBP). American Journal of Chemical Engineering 4. 78-86. |
[43] | Trivedi MK, Branton A, Trivedi D, Nayak G, Mishra RK, Jana S (2015) Characterization of physical, thermal and spectral properties of biofield treated 2-aminopyridine. Science Journal of Analytical Chemistry 3: 127-134. |
[44] | Trivedi MK, Branton A, Trivedi D, Nayak G, Gangwar M, Jana S (2015) Agronomic characteristics, growth analysis, and yield response of biofield treated mustard, cowpea, horse gram, and groundnuts. International Journal of Genetics and Genomics 3: 74-80. |
[45] | Trivedi MK, Branton A, Trivedi D, Nayak G, Mondal SC, Jana S (2015) Evaluation of plant growth, yield and yield attributes of biofield energy treated mustard (Brassica juncea) and chick pea (Cicer Arietinum) Seeds. Agriculture, Forestry and Fisheries 4: 291-295. |
[46] | Devkar ST, Kandhare AD, Sloley BD, Jagtap SD, Lin J, Tam YK, Katyare SS, Bodhankar SL, Hegde MV (2015) Evaluation of the bioavailability of major withanolides of Withania somnifera using an in vitro absorption model system. J Adv Pharm Technol Res 6: 159-164. |
[47] | Verma SK, Kumar A (2011) Therapeutic uses of Withania somnifera (ashwagandha) with a note on withanolides and its pharmacological actions. Asian J Pharm Clin Res 4: 1-4. |
[48] | Chereson R (2009) Bioavailability, bioequivalence, and drug selection. In: Makoid CM, Vuchetich PJ, Banakar UV (eds) Basic pharmacokinetics (1st edn) Pharmaceutical Press, London. |
[49] | Blagden N, de Matas M, Gavan PT, York P (2007) Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Adv Drug Deliv Rev 59: 617-630. |
[50] | Trivedi MK, Mohan TRR (2016) Biofield energy signals, energy transmission and neutrinos. American Journal of Modern Physics 5: 172-176. |
[51] | Khadka P, Ro J, Kim H, Kim I, Kim JT, Kim H, Cho JM, Yun G, Lee J (2014) Pharmaceutical particle technologies: An approach to improve drug solubility, dissolution and bioavailability. Asian J Pharm Sci 9. 304-316. |
[52] | Buckton G, Beezer AE (1992) The relationship between particle size and solubility. Int J Pharmaceutics 82: R7-R10. |
[53] | Reichenbacher M, Popp J (2012) Challenges in Molecular structure determination, DOI 10.1007/978-3-642-24390-5_2, Springer-Verlag Berlin Heidelberg. |
[54] | Stuart BH (2004) Infrared spectroscopy: Fundamentals and applications in Analytical Techniques in the Sciences. John Wiley & Sons Ltd., Chichester, UK. |
[55] | Joshi P, Misra L, Siddique AA, Srivastava M, Kumar S, Darokar MP (2014) Epoxide group relationship with cytotoxicity in withanolide derivatives from Withania somnifera. Steroids 79: 19-27. |
[56] | Misra L, Lal P, Chaurasia ND, Sangwan RS, Sinha S, Tuli R (2008) Selective reactivity of 2-mercaptoethanol with 5β, 6β-epoxide in steroids from Withania somnifera. Steroids 73: 245-251. |
[57] | Gu M, Yu Y, Gunaherath GMKB, Leslie Gunatilaka AA, Li D, Sun D (2014) Structure-activity relationship (SAR) of withanolides to inhibit Hsp90 for its activity in pancreatic cancer cells. Invest New Drugs 32: 68-74. |
[58] | Ramachandran A, Kumar MS (2014) FT-IR, UV and antimicrobial activity Withania somnifera and Withania obtusifolia. Int J Pharm Bio Sci 5. (B) 111-117. |
[59] | Hesse M, Meier H, Zeeh B (1997) Spectroscopic methods in organic chemistry, Georg Thieme Verlag Stuttgart, New York. |
[60] | Zhang M, Efremov MY, Schiettekatte F, Olson EA, Kwan AT, Lai SL, Wisleder T, Greene JE, Allen LH (2000) Size-dependent melting point depression of nanostructures: Nanocalorimetric measurements. Phys Rev B 62: 10548. |
APA Style
Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Aileen Carol Lee, et al. (2017). Impact of Consciousness Energy Healing Treatment (The Trivedi Effect®) on Physical, Spectroscopic, and Thermal Properties of Withania somnifera (Ashwagandha) Root Extract. International Journal of Food Science and Biotechnology, 2(1), 6-15. https://doi.org/10.11648/j.ijfsb.20170201.12
ACS Style
Mahendra Kumar Trivedi; Alice Branton; Dahryn Trivedi; Gopal Nayak; Aileen Carol Lee, et al. Impact of Consciousness Energy Healing Treatment (The Trivedi Effect®) on Physical, Spectroscopic, and Thermal Properties of Withania somnifera (Ashwagandha) Root Extract. Int. J. Food Sci. Biotechnol. 2017, 2(1), 6-15. doi: 10.11648/j.ijfsb.20170201.12
AMA Style
Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Aileen Carol Lee, et al. Impact of Consciousness Energy Healing Treatment (The Trivedi Effect®) on Physical, Spectroscopic, and Thermal Properties of Withania somnifera (Ashwagandha) Root Extract. Int J Food Sci Biotechnol. 2017;2(1):6-15. doi: 10.11648/j.ijfsb.20170201.12
@article{10.11648/j.ijfsb.20170201.12, author = {Mahendra Kumar Trivedi and Alice Branton and Dahryn Trivedi and Gopal Nayak and Aileen Carol Lee and Aksana Hancharuk and Carola Marina Sand and Debra Jane Schnitzer and Rudina Thanasi and Eileen Mary Meagher and Faith Ann Pyka and Gary Richard Gerber and Johanna Catharina Stromsnas and Judith Marian Shapiro and Laura Nelson Streicher and Lorraine Marie Hachfeld and Matthew Charles Hornung and Patricia M. Rowe and Sally Jean Henderson and Sheila Maureen Benson and Shirley Theresa Holmlund and Stephen P. Salters and Parthasarathi Panda and Snehasis Jana}, title = {Impact of Consciousness Energy Healing Treatment (The Trivedi Effect®) on Physical, Spectroscopic, and Thermal Properties of Withania somnifera (Ashwagandha) Root Extract}, journal = {International Journal of Food Science and Biotechnology}, volume = {2}, number = {1}, pages = {6-15}, doi = {10.11648/j.ijfsb.20170201.12}, url = {https://doi.org/10.11648/j.ijfsb.20170201.12}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijfsb.20170201.12}, abstract = {Withania somnifera (Ashwagandha) root extract and their active metabolites possess a broad range of pharmacological activities. The current study aimed to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing) on the physical, spectroscopic, and thermal properties of ashwagandha root extract using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Ashwagandha root extract was divided into two parts – one part was control without any and another part was treated with The Trivedi Effect® - Energy of Consciousness Healing Treatment remotely by eighteen renowned Biofield Energy Healers and defined as The Trivedi Effect® treated sample. The PXRD analysis exhibited that both the treated and control samples were amorphous in nature. The particle sizes at d10, d50, and d90 values of the treated sample were significantly decreased by 12.23%, 10.97%, and 1.25%, respectively with respect to the control sample. The surface area analysis revealed that the surface area of the treated sample was significantly increased by 14.29% as compared to the control sample. The FT-IR analysis indicated the alteration of the force constant for the functional groups of the treated sample in comparison to the control sample. The UV-vis analysis revealed that the wavelength for the maximum absorbance of the control and treated samples were at 205.8 and 206.0 nm, respectively. The TGA analysis revealed that the total weight loss was decreased by 0.70% in the treated sample as compared to the control sample. This indicated that the treated sample was thermally more stable as compared to the control sample. The DSC analysis indicated that the melting point of the treated sample (190.48°C) was decreased by 4.91% than the control sample (203.45°C). The latent heat of fusion of the treated (4.94 J/g) sample was significantly decreased by 42.96% compared with the control (8.66 J/g) sample. The current findings suggest that The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing) might have the astounding capacity to enhance the solubility, absorption, dissolution, and finally, bioavailability of ashwagandha root extract in various form of pharmaceutical and nutraceutical formulation by modifying its particle size and surface area. Thus, the treated ashwagandha root extract might provide better therapeutic response against against inflammatory diseases, immunological disorders, stress, arthritis, cancer, diabetes, sexual disorders, aging and other chronic infections.}, year = {2017} }
TY - JOUR T1 - Impact of Consciousness Energy Healing Treatment (The Trivedi Effect®) on Physical, Spectroscopic, and Thermal Properties of Withania somnifera (Ashwagandha) Root Extract AU - Mahendra Kumar Trivedi AU - Alice Branton AU - Dahryn Trivedi AU - Gopal Nayak AU - Aileen Carol Lee AU - Aksana Hancharuk AU - Carola Marina Sand AU - Debra Jane Schnitzer AU - Rudina Thanasi AU - Eileen Mary Meagher AU - Faith Ann Pyka AU - Gary Richard Gerber AU - Johanna Catharina Stromsnas AU - Judith Marian Shapiro AU - Laura Nelson Streicher AU - Lorraine Marie Hachfeld AU - Matthew Charles Hornung AU - Patricia M. Rowe AU - Sally Jean Henderson AU - Sheila Maureen Benson AU - Shirley Theresa Holmlund AU - Stephen P. Salters AU - Parthasarathi Panda AU - Snehasis Jana Y1 - 2017/03/09 PY - 2017 N1 - https://doi.org/10.11648/j.ijfsb.20170201.12 DO - 10.11648/j.ijfsb.20170201.12 T2 - International Journal of Food Science and Biotechnology JF - International Journal of Food Science and Biotechnology JO - International Journal of Food Science and Biotechnology SP - 6 EP - 15 PB - Science Publishing Group SN - 2578-9643 UR - https://doi.org/10.11648/j.ijfsb.20170201.12 AB - Withania somnifera (Ashwagandha) root extract and their active metabolites possess a broad range of pharmacological activities. The current study aimed to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing) on the physical, spectroscopic, and thermal properties of ashwagandha root extract using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Ashwagandha root extract was divided into two parts – one part was control without any and another part was treated with The Trivedi Effect® - Energy of Consciousness Healing Treatment remotely by eighteen renowned Biofield Energy Healers and defined as The Trivedi Effect® treated sample. The PXRD analysis exhibited that both the treated and control samples were amorphous in nature. The particle sizes at d10, d50, and d90 values of the treated sample were significantly decreased by 12.23%, 10.97%, and 1.25%, respectively with respect to the control sample. The surface area analysis revealed that the surface area of the treated sample was significantly increased by 14.29% as compared to the control sample. The FT-IR analysis indicated the alteration of the force constant for the functional groups of the treated sample in comparison to the control sample. The UV-vis analysis revealed that the wavelength for the maximum absorbance of the control and treated samples were at 205.8 and 206.0 nm, respectively. The TGA analysis revealed that the total weight loss was decreased by 0.70% in the treated sample as compared to the control sample. This indicated that the treated sample was thermally more stable as compared to the control sample. The DSC analysis indicated that the melting point of the treated sample (190.48°C) was decreased by 4.91% than the control sample (203.45°C). The latent heat of fusion of the treated (4.94 J/g) sample was significantly decreased by 42.96% compared with the control (8.66 J/g) sample. The current findings suggest that The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing) might have the astounding capacity to enhance the solubility, absorption, dissolution, and finally, bioavailability of ashwagandha root extract in various form of pharmaceutical and nutraceutical formulation by modifying its particle size and surface area. Thus, the treated ashwagandha root extract might provide better therapeutic response against against inflammatory diseases, immunological disorders, stress, arthritis, cancer, diabetes, sexual disorders, aging and other chronic infections. VL - 2 IS - 1 ER -