Background: According to Globocan 2020, the global burden of cancer has increased to 19.3 million cases and 10 million cancer deaths. The International Agency for Research on Cancer estimates that, in the world, one in five people develop cancer during their lifetime. Urinary tract cancers are common in urology. They are most often of a bad prognosis. While the epidemiology of urological cancers is well known in the Northern Countries, data on these conditions are little available or insufficient. The purpose of this study was to determine the frequency of urological cancers, describe their clinical presentation and classification. Methodology: We conducted a transversal study in the urology, oncology and pathology anatomy departments of the Douala General Hospital (DGH) and the Douala Laquintinie Hospital (DLH). Medical records and pathology reports of biopsies carried out on patients with urological cancer and hospitalized over a period of 10 years from January 1, 2010 to December 31, 2019 were included. Results: A total of 93 cases were selected. The sex ratio of 8:1. The average age was 64.7±11.51 years for men and 45.8±23 years for women (p=0.030). Smoking was the main comorbidity (30.1%). Low back pain, hematuria and urine retention were the main modes of revelation. Prostate cancer was found in 75.3%. Prostate adenocarcinoma was the most found histological type (94.1%) Kidney, bladder and penis cancer were found in 16.1%; 7.5% and 1% of cases. More than half of patients with prostate cancer (68.6%) had metastasis at the time of diagnosis. Conclusion: urological cancers affect men more. The symptomatology is dominated by the signs of the upper and lower urinary tract. Prostate adenocarcinoma is the most found histological type.
Published in | International Journal of Clinical Urology (Volume 8, Issue 2) |
DOI | 10.11648/j.ijcu.20240802.15 |
Page(s) | 39-43 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Urological Cancer, Epidemiological and Histological Profile, Douala
[1] | Ngwa W, Addai BW, Adewole I, Ainsworth V, Alaro J, Alatise OI, et al. Cancer in sub-Saharan Africa: a Lancet Oncology Commission. Lancet Oncol. juin 2022; 23(6): e251-312. |
[2] | Darré T, Folligan K, Kpatcha TM, Kanassoua K, Sewa E, Daré S, et al. Evolution of the Histo-Epidemiological Profile of Urological Cancers in Togo. Asian Pac J Cancer Prev APJCP. 1 févr 2017; 18(2): 491-4. |
[3] | Scn K, Nm T, M F, A D, C D, Y D, et al. Epidemiological, Clinical and Histological Profile of Urogenital Cancers in the Thies Region in Senegal. Arch Urol. Sryahwa Publications LLC; 19 déc 2023; 5(1): 27-33. |
[4] | OUATTARA A, Hodonou R, Avakoudjo J, Cisse D, Zango B, Gandaho I, et al. Epidemiology of urologic cancers in university teaching hospital of Cotonou, Benin. Review about 158 cases of urologic cancers. Prog En Urol J Assoc Fr Urol Société Fr Urol. 1 mai 2012; 22: 261-5. |
[5] | Abdulkadir A, Alhaji SA, Sanusi HM. Pattern of urological cancers in Kano: North-western Nigeria. Sub-Sahar Afr J Med. déc 2016; 3(4): 182. |
[6] | Bowa K, Kachimba JS, Labib MA, Mudenda V, Chikwenya M. The pattern of urological cancers in Zambia. Afr J Urol. SpringerOpen; juin 2009; 15(2): 84-7. |
[7] | A 15-year review of clinical and pathological aspects of urologic cancers in two referral hospitals in Yaounde (Cameroon). Adv Cytol Pathol [Internet]. MedCrave Publishing; 28 sept 2018 [cité 22 juill 2024]; Volume 3(Issue 4). Disponible sur: |
[8] | Mohamed AH, Abdullahi IM, Eraslan A, Mohamud HA, Gur M. Epidemiological and Histopathological Characteristics of Renal Cell Carcinoma in Somalia. Cancer Manag Res. 30 mai 2022; 14: 1837-44. |
[9] | Yaxley JP. Urinary tract cancers: An overview for general practice. J Fam Med Prim Care. 2016; 5(3): 533-8. |
[10] |
Renal Cell Carcinoma: Practice Essentials, Background, Pathophysiology. 3 avr 2024 [cité 23 juill 2024]; Disponible sur:
https://emedicine.medscape.com/article/281340-overview?form=fpf |
[11] | Ziu E, Viswanathan VK, Mesfin FB. Spinal Metastasis. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 [cité 23 juill 2024]. Disponible sur: |
[12] | Teoh JY-C. Epidemiology and screening for urologic cancers. World J Urol. 1 avr 2023; 41(4): 897-8. |
[13] | Li J, Deng Z, Soerensen SJC, Kachuri L, Cardenas A, Graff RE, et al. Ambient air pollution and urological cancer risk: A systematic review and meta-analysis of epidemiological evidence. Nat Commun. Nature Publishing Group; 15 juin 2024; 15(1): 5116. |
[14] | Buanza RL, Lukuke JO, Lolangwa FB, Muela AM, et al. Epidemiological and Histopathological Profile of Prostate Cancer: A Retrospective Study in the Pathology Department of the University Clinics of Kinshasa. J Cancer Ther. Scientific Research Publishing; 13 juin 2024; 15(6): 239-49. |
[15] | Adeloye D, David RA, Aderemi AV, Iseolorunkanmi A, Oyedokun A, Iweala EEJ, et al. An Estimate of the Incidence of Prostate Cancer in Africa: A Systematic Review and Meta-Analysis. PloS One. 2016; 11(4): e0153496. |
[16] | Kirakoya B, Hounnasso P, Pare A, Mustapha A, Zango B. CLINICO-PATHOLOGICAL FEATURES OF PROSTATE CANCER AT THE UNIVERSITY HOSPITAL YALGADO OUEDRAOGO, OUAGADOUGOU, BURKINA FASO. J West Afr Coll Surg. 2014; 4(4): 70-81. |
[17] | Humphrey PA. Histological variants of prostatic carcinoma and their significance. Histopathology. 2012; 60(1): 59-74. |
[18] | Miller DC, Hafez KS, Stewart A, Montie JE, Wei JT. Prostate carcinoma presentation, diagnosis, and staging: an update form the National Cancer Data Base. Cancer. 15 sept 2003; 98(6): 1169-78. |
[19] | Zhang J, Cai D, Hong S. Prevalence and prognosis of bone metastases in common solid cancers at initial diagnosis: a population-based study. BMJ Open. British Medical Journal Publishing Group; 1 Oct 2023; 13(10): e069908. |
[20] | Muglia VF, Prando A. Renal cell carcinoma: histological classification and correlation with imaging findings. Radiol Bras. 2015; 48(3): 166-74. |
[21] | Pallagani L, Choudhary GR, Himanshu P, Madduri VKS, Singh M, Gupta P, et al. Epidemiology and Clinicopathological Profile of Renal Cell Carcinoma: A Review from Tertiary Care Referral Centre. J Kidney Cancer VHL. 20 janv 2021; 8(1): 1-6. |
[22] | Berthé HJG, Cissé D, Diallo MS, Kassogué A, Diarra A, Coulibaly MT, et al. Bladder Cancer: Epidemiological, Clinical and Histopathological Aspects at the University Hospital Point G, Mali. Open J Urol. Scientific Research Publishing; 19 oct 2021; 11(10): 343-50. |
[23] | Edwige Meguem ABFD. La schistosomiase urinaire: un problème de santé publique en zone rurale dans le département du Mungo au Cameroun [Internet]. Zenodo; 2024 [cité 24 juill 2024]. Disponible sur: |
[24] | Chippaux J-P, éditeur. La lutte contre les schistosomoses en Afrique de l’Ouest. Paris: Éditions IRD; 2000. 290 p. |
[25] | Jalloh M, Cassell A, Diallo T, Gaye O, Ndoye M, Mbodji MM, et al. Is Schistosomiasis a Risk Factor for Bladder Cancer? Evidence-Based Facts. J Trop Med. 1 juin 2020; 8270810. |
[26] | Efared B, Bako ABA, Idrissa B, Alhousseini D, Boureima HS, Sodé HC, et al. Urinary bladder Schistosoma haematobium-related squamous cell carcinoma: a report of two fatal cases and literature review. Trop Dis Travel Med Vaccines. 15 févr 2022; 8(1): 3. |
APA Style
Guy, E. N. F., Stéphane, N. M. A., Oriol, M. L., Quentin, E. A., Nkeng, G., et al. (2024). Urological Cancers in Douala (Cameroon): Epidemiological and Histological Profile. International Journal of Clinical Urology, 8(2), 39-43. https://doi.org/10.11648/j.ijcu.20240802.15
ACS Style
Guy, E. N. F.; Stéphane, N. M. A.; Oriol, M. L.; Quentin, E. A.; Nkeng, G., et al. Urological Cancers in Douala (Cameroon): Epidemiological and Histological Profile. Int. J. Clin. Urol. 2024, 8(2), 39-43. doi: 10.11648/j.ijcu.20240802.15
AMA Style
Guy ENF, Stéphane NMA, Oriol ML, Quentin EA, Nkeng G, et al. Urological Cancers in Douala (Cameroon): Epidemiological and Histological Profile. Int J Clin Urol. 2024;8(2):39-43. doi: 10.11648/j.ijcu.20240802.15
@article{10.11648/j.ijcu.20240802.15, author = {Epoupa Ngalle Frantz Guy and Nwaha Makon Axel Stéphane and Mbouché Landry Oriol and Essomba Armel Quentin and Glenda Nkeng and Soppo Ekoule Christian Aristide and Atangana Cédric Paterson and Moby Mpah Edouard Hervé and Fouda Pierre Joseph}, title = {Urological Cancers in Douala (Cameroon): Epidemiological and Histological Profile }, journal = {International Journal of Clinical Urology}, volume = {8}, number = {2}, pages = {39-43}, doi = {10.11648/j.ijcu.20240802.15}, url = {https://doi.org/10.11648/j.ijcu.20240802.15}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20240802.15}, abstract = {Background: According to Globocan 2020, the global burden of cancer has increased to 19.3 million cases and 10 million cancer deaths. The International Agency for Research on Cancer estimates that, in the world, one in five people develop cancer during their lifetime. Urinary tract cancers are common in urology. They are most often of a bad prognosis. While the epidemiology of urological cancers is well known in the Northern Countries, data on these conditions are little available or insufficient. The purpose of this study was to determine the frequency of urological cancers, describe their clinical presentation and classification. Methodology: We conducted a transversal study in the urology, oncology and pathology anatomy departments of the Douala General Hospital (DGH) and the Douala Laquintinie Hospital (DLH). Medical records and pathology reports of biopsies carried out on patients with urological cancer and hospitalized over a period of 10 years from January 1, 2010 to December 31, 2019 were included. Results: A total of 93 cases were selected. The sex ratio of 8:1. The average age was 64.7±11.51 years for men and 45.8±23 years for women (p=0.030). Smoking was the main comorbidity (30.1%). Low back pain, hematuria and urine retention were the main modes of revelation. Prostate cancer was found in 75.3%. Prostate adenocarcinoma was the most found histological type (94.1%) Kidney, bladder and penis cancer were found in 16.1%; 7.5% and 1% of cases. More than half of patients with prostate cancer (68.6%) had metastasis at the time of diagnosis. Conclusion: urological cancers affect men more. The symptomatology is dominated by the signs of the upper and lower urinary tract. Prostate adenocarcinoma is the most found histological type. }, year = {2024} }
TY - JOUR T1 - Urological Cancers in Douala (Cameroon): Epidemiological and Histological Profile AU - Epoupa Ngalle Frantz Guy AU - Nwaha Makon Axel Stéphane AU - Mbouché Landry Oriol AU - Essomba Armel Quentin AU - Glenda Nkeng AU - Soppo Ekoule Christian Aristide AU - Atangana Cédric Paterson AU - Moby Mpah Edouard Hervé AU - Fouda Pierre Joseph Y1 - 2024/11/18 PY - 2024 N1 - https://doi.org/10.11648/j.ijcu.20240802.15 DO - 10.11648/j.ijcu.20240802.15 T2 - International Journal of Clinical Urology JF - International Journal of Clinical Urology JO - International Journal of Clinical Urology SP - 39 EP - 43 PB - Science Publishing Group SN - 2640-1355 UR - https://doi.org/10.11648/j.ijcu.20240802.15 AB - Background: According to Globocan 2020, the global burden of cancer has increased to 19.3 million cases and 10 million cancer deaths. The International Agency for Research on Cancer estimates that, in the world, one in five people develop cancer during their lifetime. Urinary tract cancers are common in urology. They are most often of a bad prognosis. While the epidemiology of urological cancers is well known in the Northern Countries, data on these conditions are little available or insufficient. The purpose of this study was to determine the frequency of urological cancers, describe their clinical presentation and classification. Methodology: We conducted a transversal study in the urology, oncology and pathology anatomy departments of the Douala General Hospital (DGH) and the Douala Laquintinie Hospital (DLH). Medical records and pathology reports of biopsies carried out on patients with urological cancer and hospitalized over a period of 10 years from January 1, 2010 to December 31, 2019 were included. Results: A total of 93 cases were selected. The sex ratio of 8:1. The average age was 64.7±11.51 years for men and 45.8±23 years for women (p=0.030). Smoking was the main comorbidity (30.1%). Low back pain, hematuria and urine retention were the main modes of revelation. Prostate cancer was found in 75.3%. Prostate adenocarcinoma was the most found histological type (94.1%) Kidney, bladder and penis cancer were found in 16.1%; 7.5% and 1% of cases. More than half of patients with prostate cancer (68.6%) had metastasis at the time of diagnosis. Conclusion: urological cancers affect men more. The symptomatology is dominated by the signs of the upper and lower urinary tract. Prostate adenocarcinoma is the most found histological type. VL - 8 IS - 2 ER -