A 57-year-old woman with chronic hemodialysis for 16 years, who presented at the Avicenna hospital in Marrakesh with fever and hepatosplenomegaly. Three months earlier, he received 2 units of packed red blood cells. Laboratory studies indicated hemolytic anemia (hemoglobin, 9.5 mg/dl) and thrombocytopenia (platelet count, 105000/mm2). Malaria smear was consistent with Plasmodium malariae. The level of parasetemia was 1% (10 per 1000 erythrocytes). As a result, the patient's antimalarial therapy was continued for a total of 7 days followed by mefloquine for 7 days once the blood smear results revealed P. malariae infection. Evolution was favorable after antimalarial therapy with the disappeanrance of fever and hepatosplenomegaly. The control of parasitaemia remained negative until 28 days. This is the first case of hepatosplenomegaly secondary to blood transfusion related Plasmodium malariae infection in a non-endemic country in chronic hemodialysis.
Published in | International Journal of Clinical Urology (Volume 1, Issue 1) |
DOI | 10.11648/j.ijcu.20170101.14 |
Page(s) | 15-18 |
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Copyright © The Author(s), 2017. Published by Science Publishing Group |
Chronic Hemodialisis, Malaria Transfusion, Plasmodium malariae
[1] | Clive R. Seed, Alan Kitchen, Timothy M. E. Davis Transfusion Medicine Reviews, Vol 19, No 3 (July), 2005: pp 229-24. |
[2] | S. Haydoura et al. Transfusion-related Plasmodium ovale malaria complicated by acute respiratory distress syndrome (ARDS) in a non-endemic country Parasitology International 60 (2011) 114–116. |
[3] | Laishram DD, Sutton PL, Nanda N, Sharma VL, Sobti RC, Carlton JM, Joshi H. The complexities of malaria disease manifestations with a focus on asymptomatic malaria. Malar J. 2012; 12: 29. |
[4] | Benito A and Rubio JM. Usefulness of Seminested Polymerase Chain Reaction for Screening Blood Donors at Risk for Malaria in Spain. Emerging Infectious Diseases. 2001; 7, (6): 1068. |
[5] | Bemelman F, De Blok K, De Vries P and al. falciparum malaria transmitted by a thick blood smear negative kidney donor. Scandinavian journal of infectious diseases. 2004; 36: 769-771. |
[6] | Nahlen BL, Lobel HO, Cannon SE, Campbell CC. Reassessment of blood donor selection criteria for United States travelers to malarious areas. Transfus 1991; 31: 798–804. |
[7] | Mungai M, Tegtmeier G, Chamberland M, Parise M. Transfusion transmitted malaria in the United States from 1963 through 1999. N Engl J Med 2001; 344: 1973–8. |
[8] | Candolfi E. Transfusion transmitted malaria, preventive measures. Transfusion Clinique et Biologique. 2005; 12: 107–113. |
[9] | Silvie O, Thellier M, Rosenheim M, Datry A, Lavigne P, Danis M, et al. Potential value of Plasmodium falciparum-associated antigen and antibody detection for screening of blood donors to prevent transfusion-transmitted malaria. Transfusion 2002; 42: 357–62. |
[10] | Legros F, Danis M. Malaria in France in 1998. CNRMI Bull 1999; 15: 1-34. |
[11] | Danic B, Becel C, Beauplet A. Is it possible to organize into a hierarchy the blood donations contraindications? Transfusion Clinique et Biologique. 2002; 9: 280-285. |
[12] | Transfusion-Transmitted Malaria: How Satisfactory Are Current Preventative Measures? The American Journal of Medicine (2006) 119, e1-e2. |
[13] | Danic B. Clinical selection of blood donors. Transfusion Clinique et Biologique. 2003; 10: 227-233. |
[14] | Garraud O, Elghouzzi M-H. Post-transfusion parasite transmission: do the present controls fit with the EU directive? Transfusion Clinique et Biologique. 2005; 12: 275–285. |
[15] | Kitchen A, Chiodini P. Malaria and blood transfusion. Vox Sanguinis. 2006; 90: 77–84. |
[16] | Moiz B. Prevention of Transfusion Transmitted Malaria in an Endemic area– A Challenge for Blood Banks. Infectious Diseases Journal of Pakistan. 2004; 96-98. |
[17] | Tayou Tagny C, Mbanya D, Garraud O and all. Blood safety: Malaria and blood donation in Africa. Transfusion Clinique et Biologique. 2007; 14: 481–486. |
[18] | Bruneel F, Thellier M, Eloy O. Transfusion-transmitted malaria. Intensive Care Medicine. 2004; 30: 1851-1852. |
[19] | Naegelen C, Isola H, Dernis D. Evolution des techniques de préparation des produits sanguins labiles (PSL): inactivation des pathogènes dans les PSL. Transfusion Clinique et Biologique. 2009; 16: 179–189. |
[20] | Slinger R, Giulivi A, Bodie-Collins M. Transfusion-transmitted malaria in Canada. Canadian Medical Association Journal. 2001; 164 (3): 377-379. |
[21] | Danic B. Stating technical requirements and deferral criteria for whole blood donation. Transfusion Clinique et Biologique. 2005; 12: 287–289. |
[22] | Jun Seo O, Jang Su K, Chang Hwan L and al. Evaluation of a malaria antibody enzyme immunoassay for use in blood screening. Memorises of the Institut Oswaldo Cruz. 2008; 103(1): 75-78. |
APA Style
El Mezouari El Mostafa, Benjelloun Imane, Belarbi Marouane, Ait Ameur Mustapha, Chakour Mohamed, et al. (2017). A Case Report of Transfusion-Transmitted Plasmodium malariae in a Non-endemic Country. International Journal of Clinical Urology, 1(1), 15-18. https://doi.org/10.11648/j.ijcu.20170101.14
ACS Style
El Mezouari El Mostafa; Benjelloun Imane; Belarbi Marouane; Ait Ameur Mustapha; Chakour Mohamed, et al. A Case Report of Transfusion-Transmitted Plasmodium malariae in a Non-endemic Country. Int. J. Clin. Urol. 2017, 1(1), 15-18. doi: 10.11648/j.ijcu.20170101.14
@article{10.11648/j.ijcu.20170101.14, author = {El Mezouari El Mostafa and Benjelloun Imane and Belarbi Marouane and Ait Ameur Mustapha and Chakour Mohamed and Zyani Mohamed and Zemraoui Nadir and Moutaj Redouane}, title = {A Case Report of Transfusion-Transmitted Plasmodium malariae in a Non-endemic Country}, journal = {International Journal of Clinical Urology}, volume = {1}, number = {1}, pages = {15-18}, doi = {10.11648/j.ijcu.20170101.14}, url = {https://doi.org/10.11648/j.ijcu.20170101.14}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20170101.14}, abstract = {A 57-year-old woman with chronic hemodialysis for 16 years, who presented at the Avicenna hospital in Marrakesh with fever and hepatosplenomegaly. Three months earlier, he received 2 units of packed red blood cells. Laboratory studies indicated hemolytic anemia (hemoglobin, 9.5 mg/dl) and thrombocytopenia (platelet count, 105000/mm2). Malaria smear was consistent with Plasmodium malariae. The level of parasetemia was 1% (10 per 1000 erythrocytes). As a result, the patient's antimalarial therapy was continued for a total of 7 days followed by mefloquine for 7 days once the blood smear results revealed P. malariae infection. Evolution was favorable after antimalarial therapy with the disappeanrance of fever and hepatosplenomegaly. The control of parasitaemia remained negative until 28 days. This is the first case of hepatosplenomegaly secondary to blood transfusion related Plasmodium malariae infection in a non-endemic country in chronic hemodialysis.}, year = {2017} }
TY - JOUR T1 - A Case Report of Transfusion-Transmitted Plasmodium malariae in a Non-endemic Country AU - El Mezouari El Mostafa AU - Benjelloun Imane AU - Belarbi Marouane AU - Ait Ameur Mustapha AU - Chakour Mohamed AU - Zyani Mohamed AU - Zemraoui Nadir AU - Moutaj Redouane Y1 - 2017/10/11 PY - 2017 N1 - https://doi.org/10.11648/j.ijcu.20170101.14 DO - 10.11648/j.ijcu.20170101.14 T2 - International Journal of Clinical Urology JF - International Journal of Clinical Urology JO - International Journal of Clinical Urology SP - 15 EP - 18 PB - Science Publishing Group SN - 2640-1355 UR - https://doi.org/10.11648/j.ijcu.20170101.14 AB - A 57-year-old woman with chronic hemodialysis for 16 years, who presented at the Avicenna hospital in Marrakesh with fever and hepatosplenomegaly. Three months earlier, he received 2 units of packed red blood cells. Laboratory studies indicated hemolytic anemia (hemoglobin, 9.5 mg/dl) and thrombocytopenia (platelet count, 105000/mm2). Malaria smear was consistent with Plasmodium malariae. The level of parasetemia was 1% (10 per 1000 erythrocytes). As a result, the patient's antimalarial therapy was continued for a total of 7 days followed by mefloquine for 7 days once the blood smear results revealed P. malariae infection. Evolution was favorable after antimalarial therapy with the disappeanrance of fever and hepatosplenomegaly. The control of parasitaemia remained negative until 28 days. This is the first case of hepatosplenomegaly secondary to blood transfusion related Plasmodium malariae infection in a non-endemic country in chronic hemodialysis. VL - 1 IS - 1 ER -