Introduction: Breast cancer (BC) is a major public health challenge in Sub-Saharan Africa (SSA) due to late diagnosis and low survival. Studying "long-term survivors" is essential to identifying resilience factors and successful strategies. This study aims to describe the epidemiological, clinical, and therapeutic characteristics of long-term breast cancer survivors at the Yaounde General Hospital (YGH) in Cameroon and and identify factors associated with prolonged survival. Methods: In this retrospective cohort study (2008–2018), we analyzed 204 patient records. Long-term survivors were defined as the 68 patients (33.3% of the cohort) who survived for at least three years after their diagnosis. Data were collected using a standardized questionnaire. Descriptive statistics were used to detail their profile. Prognostic factors were identified using a Cox regression model. Results: The cohort was predominantly female (98.5%), with a median overall survival of 73.92 months (6.16 years). Patients were typically diagnosed at earlier stages (IIA, IIB, IIIA), and signs of locally advanced disease were rare. Key prognostic factors included (OR = 8.3, p<0.001), radiotherapy (OR = 2.7, p=0.001), and hormone therapy (OR = 2.9, p=0.001), and achieving a complete clinical response to initial treatment (OR = 4.5, p<0.001). The paradoxical association between relapse occurrence (OR = 2.8, p=0.001), and prolonged survival highlights the role of rigorous follow-up. Conclusion: Long-term survivors are characterized by less aggressive initial presentation and access to complete, multimodal treatment. Prioritizing early diagnosis and continuous oncological follow-up is key to improving regional prognosis.
| Published in | International Journal of Clinical Oncology and Cancer Research (Volume 10, Issue 4) |
| DOI | 10.11648/j.ijcocr.20251004.11 |
| Page(s) | 127-134 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2025. Published by Science Publishing Group |
Long-term Survivors, Breast Cancer, Profile, Cameroon
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APA Style
Mapoko, B. S. E., Bell, E. D., Mboua, V. B., Ndi, K. C., Atenguena, E., et al. (2025). Epidemiological, Clinical, and Therapeutic Profile of Long-term Breast Cancer Survivors in Cameroon: A Retrospective Cohort Study. International Journal of Clinical Oncology and Cancer Research, 10(4), 127-134. https://doi.org/10.11648/j.ijcocr.20251004.11
ACS Style
Mapoko, B. S. E.; Bell, E. D.; Mboua, V. B.; Ndi, K. C.; Atenguena, E., et al. Epidemiological, Clinical, and Therapeutic Profile of Long-term Breast Cancer Survivors in Cameroon: A Retrospective Cohort Study. Int. J. Clin. Oncol. Cancer Res. 2025, 10(4), 127-134. doi: 10.11648/j.ijcocr.20251004.11
@article{10.11648/j.ijcocr.20251004.11,
author = {Berthe Sabine Esson Mapoko and Esther Dina Bell and Veronique Batoum Mboua and Kenn Chi Ndi and Etienne Atenguena and Dominique Anaba and Lionel Tabola and Pelagie Douanla and Anne Sango and Ruth Mapenya and Anne Marthe Maison and Sidonie Ananga and Ambroise Ntama and Zacharie Sando and Paul Ndom},
title = {Epidemiological, Clinical, and Therapeutic Profile of Long-term Breast Cancer Survivors in Cameroon: A Retrospective Cohort Study
},
journal = {International Journal of Clinical Oncology and Cancer Research},
volume = {10},
number = {4},
pages = {127-134},
doi = {10.11648/j.ijcocr.20251004.11},
url = {https://doi.org/10.11648/j.ijcocr.20251004.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20251004.11},
abstract = {Introduction: Breast cancer (BC) is a major public health challenge in Sub-Saharan Africa (SSA) due to late diagnosis and low survival. Studying "long-term survivors" is essential to identifying resilience factors and successful strategies. This study aims to describe the epidemiological, clinical, and therapeutic characteristics of long-term breast cancer survivors at the Yaounde General Hospital (YGH) in Cameroon and and identify factors associated with prolonged survival. Methods: In this retrospective cohort study (2008–2018), we analyzed 204 patient records. Long-term survivors were defined as the 68 patients (33.3% of the cohort) who survived for at least three years after their diagnosis. Data were collected using a standardized questionnaire. Descriptive statistics were used to detail their profile. Prognostic factors were identified using a Cox regression model. Results: The cohort was predominantly female (98.5%), with a median overall survival of 73.92 months (6.16 years). Patients were typically diagnosed at earlier stages (IIA, IIB, IIIA), and signs of locally advanced disease were rare. Key prognostic factors included (OR = 8.3, pConclusion: Long-term survivors are characterized by less aggressive initial presentation and access to complete, multimodal treatment. Prioritizing early diagnosis and continuous oncological follow-up is key to improving regional prognosis.
},
year = {2025}
}
TY - JOUR T1 - Epidemiological, Clinical, and Therapeutic Profile of Long-term Breast Cancer Survivors in Cameroon: A Retrospective Cohort Study AU - Berthe Sabine Esson Mapoko AU - Esther Dina Bell AU - Veronique Batoum Mboua AU - Kenn Chi Ndi AU - Etienne Atenguena AU - Dominique Anaba AU - Lionel Tabola AU - Pelagie Douanla AU - Anne Sango AU - Ruth Mapenya AU - Anne Marthe Maison AU - Sidonie Ananga AU - Ambroise Ntama AU - Zacharie Sando AU - Paul Ndom Y1 - 2025/12/03 PY - 2025 N1 - https://doi.org/10.11648/j.ijcocr.20251004.11 DO - 10.11648/j.ijcocr.20251004.11 T2 - International Journal of Clinical Oncology and Cancer Research JF - International Journal of Clinical Oncology and Cancer Research JO - International Journal of Clinical Oncology and Cancer Research SP - 127 EP - 134 PB - Science Publishing Group SN - 2578-9511 UR - https://doi.org/10.11648/j.ijcocr.20251004.11 AB - Introduction: Breast cancer (BC) is a major public health challenge in Sub-Saharan Africa (SSA) due to late diagnosis and low survival. Studying "long-term survivors" is essential to identifying resilience factors and successful strategies. This study aims to describe the epidemiological, clinical, and therapeutic characteristics of long-term breast cancer survivors at the Yaounde General Hospital (YGH) in Cameroon and and identify factors associated with prolonged survival. Methods: In this retrospective cohort study (2008–2018), we analyzed 204 patient records. Long-term survivors were defined as the 68 patients (33.3% of the cohort) who survived for at least three years after their diagnosis. Data were collected using a standardized questionnaire. Descriptive statistics were used to detail their profile. Prognostic factors were identified using a Cox regression model. Results: The cohort was predominantly female (98.5%), with a median overall survival of 73.92 months (6.16 years). Patients were typically diagnosed at earlier stages (IIA, IIB, IIIA), and signs of locally advanced disease were rare. Key prognostic factors included (OR = 8.3, pConclusion: Long-term survivors are characterized by less aggressive initial presentation and access to complete, multimodal treatment. Prioritizing early diagnosis and continuous oncological follow-up is key to improving regional prognosis. VL - 10 IS - 4 ER -