@article{10.11648/j.ijcocr.20200501.12,
  author = {Natalia Noblejas Quiles and Virginia Morillo Macías and Araceli Mayol Oltra and Fernando Ibáñez Palacín and Jorge Molina Saera and Rafael Lozoya Albalar and Enrique Boldó Roda and Stephane Antonio De Francia Cachon and María Eloísa Villaverde Domenech and Isabel Busquier Hernández and Carlos Ferrer Albiach},
  title = {Therapeutic Attitude in the Malignification of Pilonidal Cyst: Radical Treatment Associating Intraoperative Radiotherapy},
  journal = {International Journal of Clinical Oncology and Cancer Research},
  volume = {5},
  number = {1},
  pages = {5-9},
  doi = {10.11648/j.ijcocr.20200501.12},
  url = {https://doi.org/10.11648/j.ijcocr.20200501.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20200501.12},
  abstract = {Malignant degeneration on pilonidal cyst is an infrequent entity: less than 70 cases have been described in the literature. Predominantly in males around 50-60. Very slow evolution until its malignancy. Predilection for the sacrococcygeal area and epidermoid histology. Infrequent distant dissemination despite the important local extension of the primary tumor. Similar morphological and histological characteristics to anal carcinomas, using schemes of treatment based on radiotherapy and chemotherapy with radical intention according to locoregional and distance extension, associating subsequent surgery depending on the response. We describe a case of this pathology and its therapeutic management based on the literature review available. We present the case of a 70-year-old man with a pilonidal cyst malignancy in the sacrococcygeal region. Locally advanced and unresectable disease at diagnosis with skin, muscle, lymphatic and bone involvement. Pathological confirmation diagnosis established after thick needle biopsy, with a well-differentiated squamous cell carcinoma. It was decided to administer chemotherapy and radiotherapy treatment and, depending on the response evaluated by nuclear magnetic resonance, excision and/or intraoperative radiotherapy in the area of microscopic risk disease. In a second time, reconstruction using glute flaps. Early diagnosis and treatment are essential to improve the unfortunate prognosis. Surgery with curative intention is the standard of care according to locoregional extension in association with radiotherapy and chemotherapy if adverse factors or unresectable disease. In order to enhance local control, dose has been scaled allowing, besides, to minimize the acute toxicity derived from the treatment.},
 year = {2020}
}

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TY  - JOUR
T1  - Therapeutic Attitude in the Malignification of Pilonidal Cyst: Radical Treatment Associating Intraoperative Radiotherapy
AU  - Natalia Noblejas Quiles
AU  - Virginia Morillo Macías
AU  - Araceli Mayol Oltra
AU  - Fernando Ibáñez Palacín
AU  - Jorge Molina Saera
AU  - Rafael Lozoya Albalar
AU  - Enrique Boldó Roda
AU  - Stephane Antonio De Francia Cachon
AU  - María Eloísa Villaverde Domenech
AU  - Isabel Busquier Hernández
AU  - Carlos Ferrer Albiach
Y1  - 2020/01/08
PY  - 2020
N1  - https://doi.org/10.11648/j.ijcocr.20200501.12
DO  - 10.11648/j.ijcocr.20200501.12
T2  - International Journal of Clinical Oncology and Cancer Research
JF  - International Journal of Clinical Oncology and Cancer Research
JO  - International Journal of Clinical Oncology and Cancer Research
SP  - 5
EP  - 9
PB  - Science Publishing Group
SN  - 2578-9511
UR  - https://doi.org/10.11648/j.ijcocr.20200501.12
AB  - Malignant degeneration on pilonidal cyst is an infrequent entity: less than 70 cases have been described in the literature. Predominantly in males around 50-60. Very slow evolution until its malignancy. Predilection for the sacrococcygeal area and epidermoid histology. Infrequent distant dissemination despite the important local extension of the primary tumor. Similar morphological and histological characteristics to anal carcinomas, using schemes of treatment based on radiotherapy and chemotherapy with radical intention according to locoregional and distance extension, associating subsequent surgery depending on the response. We describe a case of this pathology and its therapeutic management based on the literature review available. We present the case of a 70-year-old man with a pilonidal cyst malignancy in the sacrococcygeal region. Locally advanced and unresectable disease at diagnosis with skin, muscle, lymphatic and bone involvement. Pathological confirmation diagnosis established after thick needle biopsy, with a well-differentiated squamous cell carcinoma. It was decided to administer chemotherapy and radiotherapy treatment and, depending on the response evaluated by nuclear magnetic resonance, excision and/or intraoperative radiotherapy in the area of microscopic risk disease. In a second time, reconstruction using glute flaps. Early diagnosis and treatment are essential to improve the unfortunate prognosis. Surgery with curative intention is the standard of care according to locoregional extension in association with radiotherapy and chemotherapy if adverse factors or unresectable disease. In order to enhance local control, dose has been scaled allowing, besides, to minimize the acute toxicity derived from the treatment.
VL  - 5
IS  - 1
ER  - 

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