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Evaluation of Serum Calcium, Phosphorus and Progesterone in Post-Menopausal Women in Khartoum State-Sudan

Received: 1 May 2019     Accepted: 3 June 2019     Published: 22 July 2019
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Abstract

Objective: This study was conducted to show importance of preventive measures like calcium supplementation or hormonal therapy to prevent fractures. Material and Methods: This is a comparative (analytical study), case control study. This study includes 50 blood samples, a 30 blood samples were collected from Sudanese post menopause women in a period between March to June 2018, chosen randomly from Umdwanban village, and 20 apparently healthy individuals as control to assess the effect of post menopause on calcium, phosphorus and progesterone. Self-administered questionnaire was used to collect the data. Three ml of venous blood were collected by using sterile disposable syringes and poured into lithium heparin containers, immediately centrifuged and plasma separated transferred in a plain container and processed. Stored at-20°C until analysis. These samples were evaluated for the serum levels of calcium and phosphorus determined by colorimeter and progesterone by Tosoh AIA 360, and the obtained results were analyzed by SPSS. Results: The study results showed that serum level of calcium and phosphorus was significantly changed (p<0.05) in post menopause women, the serum level of calcium is decreased and phosphorus is increased in post menopause women. The mean of serum calcium was 6.733 in test group and 8.955 in control group with p.value of 0.029 and the mean of serum phosphorus was 5.570 in test group and 3.480 in control group with p.value of 0.031. And show a non-significant difference in the serum level of progesterone between the test group and control group (P-value =0.447). Also the study showed the age and social status of the post menopause women have no effect on the serum level of calcium, phosphorus and progesterone. Conclusion: This study concluded that the serum level of calcium is decrease and phosphors is increase while progesterone is unaffected. And the age and social status of post menopause have no effect on the serum level of calcium, phosphors and progesterone.

Published in International Journal of Chinese Medicine (Volume 3, Issue 2)
DOI 10.11648/j.ijcm.20190302.14
Page(s) 30-33
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Post-Menopausal Women, Calcium, Phosphorous, Progesterone, Sudanese

References
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[3] Wood, James (2017). "9". Dynamics of Human Reproduction: Biology, Biometry, Demography. Transaction Publishers. p. 401. ISBN 9780202365701. Archived from the original on 10 September 2017.
[4] Hoffman, Barbara (2012). Williams gynecology. New York: McGraw-Hill Medical. pp. 555–56. ISBN 9780071716727.
[5] What causes menopause? Eunice Kennedy Shriver National Institute of Child Health and Human Development. 6 May 2013. Archived from the original on 2 April 2015. Retrieved 8 March 2015.
[6] Takahashi, TA; Johnson, KM (May 2015). "Menopause". The Medical clinics of North America. 99 (3): 521–34. doi: 10.1016/j.mcna.2015.01.006. PMID 25841598.
[7] Warren, volume editors, Claudio N. Soares, Michelle (2009). The menopausal transition: interface between gynecology and psychiatry ([Online-Ausg.] ed.). Basel: Karger. p. 73. ISBN 978-3805591010.
[8] Maxwell D, Fisher E, Estep H (2006). Serum alkaline phosphatase in diabetes mellitus. Journal of the American College of Nutrition, 1986; 5, 55-59.
[9] Shiber JR, Mattu A (2002). Serum phosphate abnormalities in the emergency department. J Emerg Med 2002; 23: 395–400.
[10] What are the symptoms of menopause? Eunice Kennedy Shriver National Institute of Child Health and Human Development. 6 May 2013. Archived from the original on 20 March 2015. Retrieved 8 March 2015.
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[14] Gougeon A (2016). Dynamics of follicular growth in the human: a model from preliminary results. Hum Reprod 2016; 3: 18–24.
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    Rawan Alobied Saad, Salman Taha Ahmed Elmukashfi, Amar Mohamed Saeed, Mosab Omer Khalid. (2019). Evaluation of Serum Calcium, Phosphorus and Progesterone in Post-Menopausal Women in Khartoum State-Sudan. International Journal of Chinese Medicine, 3(2), 30-33. https://doi.org/10.11648/j.ijcm.20190302.14

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    ACS Style

    Rawan Alobied Saad; Salman Taha Ahmed Elmukashfi; Amar Mohamed Saeed; Mosab Omer Khalid. Evaluation of Serum Calcium, Phosphorus and Progesterone in Post-Menopausal Women in Khartoum State-Sudan. Int. J. Chin. Med. 2019, 3(2), 30-33. doi: 10.11648/j.ijcm.20190302.14

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    AMA Style

    Rawan Alobied Saad, Salman Taha Ahmed Elmukashfi, Amar Mohamed Saeed, Mosab Omer Khalid. Evaluation of Serum Calcium, Phosphorus and Progesterone in Post-Menopausal Women in Khartoum State-Sudan. Int J Chin Med. 2019;3(2):30-33. doi: 10.11648/j.ijcm.20190302.14

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  • @article{10.11648/j.ijcm.20190302.14,
      author = {Rawan Alobied Saad and Salman Taha Ahmed Elmukashfi and Amar Mohamed Saeed and Mosab Omer Khalid},
      title = {Evaluation of Serum Calcium, Phosphorus and Progesterone in Post-Menopausal Women in Khartoum State-Sudan},
      journal = {International Journal of Chinese Medicine},
      volume = {3},
      number = {2},
      pages = {30-33},
      doi = {10.11648/j.ijcm.20190302.14},
      url = {https://doi.org/10.11648/j.ijcm.20190302.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20190302.14},
      abstract = {Objective: This study was conducted to show importance of preventive measures like calcium supplementation or hormonal therapy to prevent fractures. Material and Methods: This is a comparative (analytical study), case control study. This study includes 50 blood samples, a 30 blood samples were collected from Sudanese post menopause women in a period between March to June 2018, chosen randomly from Umdwanban village, and 20 apparently healthy individuals as control to assess the effect of post menopause on calcium, phosphorus and progesterone. Self-administered questionnaire was used to collect the data. Three ml of venous blood were collected by using sterile disposable syringes and poured into lithium heparin containers, immediately centrifuged and plasma separated transferred in a plain container and processed. Stored at-20°C until analysis. These samples were evaluated for the serum levels of calcium and phosphorus determined by colorimeter and progesterone by Tosoh AIA 360, and the obtained results were analyzed by SPSS. Results: The study results showed that serum level of calcium and phosphorus was significantly changed (p<0.05) in post menopause women, the serum level of calcium is decreased and phosphorus is increased in post menopause women. The mean of serum calcium was 6.733 in test group and 8.955 in control group with p.value of 0.029 and the mean of serum phosphorus was 5.570 in test group and 3.480 in control group with p.value of 0.031. And show a non-significant difference in the serum level of progesterone between the test group and control group (P-value =0.447). Also the study showed the age and social status of the post menopause women have no effect on the serum level of calcium, phosphorus and progesterone. Conclusion: This study concluded that the serum level of calcium is decrease and phosphors is increase while progesterone is unaffected. And the age and social status of post menopause have no effect on the serum level of calcium, phosphors and progesterone.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Evaluation of Serum Calcium, Phosphorus and Progesterone in Post-Menopausal Women in Khartoum State-Sudan
    AU  - Rawan Alobied Saad
    AU  - Salman Taha Ahmed Elmukashfi
    AU  - Amar Mohamed Saeed
    AU  - Mosab Omer Khalid
    Y1  - 2019/07/22
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ijcm.20190302.14
    DO  - 10.11648/j.ijcm.20190302.14
    T2  - International Journal of Chinese Medicine
    JF  - International Journal of Chinese Medicine
    JO  - International Journal of Chinese Medicine
    SP  - 30
    EP  - 33
    PB  - Science Publishing Group
    SN  - 2578-9473
    UR  - https://doi.org/10.11648/j.ijcm.20190302.14
    AB  - Objective: This study was conducted to show importance of preventive measures like calcium supplementation or hormonal therapy to prevent fractures. Material and Methods: This is a comparative (analytical study), case control study. This study includes 50 blood samples, a 30 blood samples were collected from Sudanese post menopause women in a period between March to June 2018, chosen randomly from Umdwanban village, and 20 apparently healthy individuals as control to assess the effect of post menopause on calcium, phosphorus and progesterone. Self-administered questionnaire was used to collect the data. Three ml of venous blood were collected by using sterile disposable syringes and poured into lithium heparin containers, immediately centrifuged and plasma separated transferred in a plain container and processed. Stored at-20°C until analysis. These samples were evaluated for the serum levels of calcium and phosphorus determined by colorimeter and progesterone by Tosoh AIA 360, and the obtained results were analyzed by SPSS. Results: The study results showed that serum level of calcium and phosphorus was significantly changed (p<0.05) in post menopause women, the serum level of calcium is decreased and phosphorus is increased in post menopause women. The mean of serum calcium was 6.733 in test group and 8.955 in control group with p.value of 0.029 and the mean of serum phosphorus was 5.570 in test group and 3.480 in control group with p.value of 0.031. And show a non-significant difference in the serum level of progesterone between the test group and control group (P-value =0.447). Also the study showed the age and social status of the post menopause women have no effect on the serum level of calcium, phosphorus and progesterone. Conclusion: This study concluded that the serum level of calcium is decrease and phosphors is increase while progesterone is unaffected. And the age and social status of post menopause have no effect on the serum level of calcium, phosphors and progesterone.
    VL  - 3
    IS  - 2
    ER  - 

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Author Information
  • Department of Clinical Chemistry, Medical Laboratory Science Program, Al-Yarmouk College, Khartoum, Sudan

  • Department of Clinical Chemistry, Medical Laboratory Science Program, Al-Yarmouk College, Khartoum, Sudan

  • Department of Clinical Chemistry, Medical Laboratory Science Program, Al-Yarmouk College, Khartoum, Sudan

  • Department of Clinical Chemistry, Faculty of Medical Laboratory Sciences, Shendi University, Shendi, Sudan

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