The present Observational study was conducted to estimate the 25-hydroxyvitamin D3 deficiency and its association with dyslipidemia in type 2 Diabetes mellitus subjects at the Department of Medicine, Isra University Hospital and Consultant Clinics Hyderabad from January 2014 to July 2014. A sample of 310 diagnosed type 2 DM were selected through non-probability purposive sampling according to inclusion and exclusion criteria. Serum 25-OH-D3 was estimated by ARCHITECT I 1000 system. Lipids sub fractions were analyzed according to standard methods. Data was analyzed on SPSS version 21.0. Data was analyzed on SPSS version 21.0. Continuous and categorical variables were analyzed by student’s t test and chi square test respectively. The associations of various lipid fractions with vitamin D3 were analyzed by Pearson’s correlation. The significant p-value was taken at ≤ 0.05. Reduced 25-hydroxyvitamin D3 levels were observed in 84.1% (n = 261). The 25-hydroxyvitamin D3 levels as low as 6ng/dl was observed in present study. The lipid profile status of subjects with normal and reduced 25-hydroxyvitamin D3 showed significant differences (p = 0.001). Triglycerides, LDLc, VLDLc, and Cholesterols exhibited an inverse correlation with 25 hydroxyvitamin D3; however a positive correlation was noted for HDL cholesterol. In conclusion, the vitamin D3 deficiency was observed in type 2 diabetic subject and showed independent association with dyslipidemia in type 2 diabetics.
| Published in | International Journal of Chinese Medicine (Volume 1, Issue 3) |
| DOI | 10.11648/j.ijcm.20170103.16 |
| Page(s) | 108-112 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2017. Published by Science Publishing Group |
25-Hydroxyvitamin D3, Dyslipidemia, Diabetes Mellitus, Sindh
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APA Style
Azhar Memon, Muhammad Atif Ata, Shumaila Shaikh, Haji Khan Khoharo. (2017). 25-Hydroxyvitamin D3 Deficiency and Dyslipidemia in Type 2 Diabetic Subjects. International Journal of Chinese Medicine, 1(3), 108-112. https://doi.org/10.11648/j.ijcm.20170103.16
ACS Style
Azhar Memon; Muhammad Atif Ata; Shumaila Shaikh; Haji Khan Khoharo. 25-Hydroxyvitamin D3 Deficiency and Dyslipidemia in Type 2 Diabetic Subjects. Int. J. Chin. Med. 2017, 1(3), 108-112. doi: 10.11648/j.ijcm.20170103.16
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Download@article{10.11648/j.ijcm.20170103.16,
author = {Azhar Memon and Muhammad Atif Ata and Shumaila Shaikh and Haji Khan Khoharo},
title = {25-Hydroxyvitamin D3 Deficiency and Dyslipidemia in Type 2 Diabetic Subjects},
journal = {International Journal of Chinese Medicine},
volume = {1},
number = {3},
pages = {108-112},
doi = {10.11648/j.ijcm.20170103.16},
url = {https://doi.org/10.11648/j.ijcm.20170103.16},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20170103.16},
abstract = {The present Observational study was conducted to estimate the 25-hydroxyvitamin D3 deficiency and its association with dyslipidemia in type 2 Diabetes mellitus subjects at the Department of Medicine, Isra University Hospital and Consultant Clinics Hyderabad from January 2014 to July 2014. A sample of 310 diagnosed type 2 DM were selected through non-probability purposive sampling according to inclusion and exclusion criteria. Serum 25-OH-D3 was estimated by ARCHITECT I 1000 system. Lipids sub fractions were analyzed according to standard methods. Data was analyzed on SPSS version 21.0. Data was analyzed on SPSS version 21.0. Continuous and categorical variables were analyzed by student’s t test and chi square test respectively. The associations of various lipid fractions with vitamin D3 were analyzed by Pearson’s correlation. The significant p-value was taken at ≤ 0.05. Reduced 25-hydroxyvitamin D3 levels were observed in 84.1% (n = 261). The 25-hydroxyvitamin D3 levels as low as 6ng/dl was observed in present study. The lipid profile status of subjects with normal and reduced 25-hydroxyvitamin D3 showed significant differences (p = 0.001). Triglycerides, LDLc, VLDLc, and Cholesterols exhibited an inverse correlation with 25 hydroxyvitamin D3; however a positive correlation was noted for HDL cholesterol. In conclusion, the vitamin D3 deficiency was observed in type 2 diabetic subject and showed independent association with dyslipidemia in type 2 diabetics.},
year = {2017}
}
TY - JOUR T1 - 25-Hydroxyvitamin D3 Deficiency and Dyslipidemia in Type 2 Diabetic Subjects AU - Azhar Memon AU - Muhammad Atif Ata AU - Shumaila Shaikh AU - Haji Khan Khoharo Y1 - 2017/07/11 PY - 2017 N1 - https://doi.org/10.11648/j.ijcm.20170103.16 DO - 10.11648/j.ijcm.20170103.16 T2 - International Journal of Chinese Medicine JF - International Journal of Chinese Medicine JO - International Journal of Chinese Medicine SP - 108 EP - 112 PB - Science Publishing Group SN - 2578-9473 UR - https://doi.org/10.11648/j.ijcm.20170103.16 AB - The present Observational study was conducted to estimate the 25-hydroxyvitamin D3 deficiency and its association with dyslipidemia in type 2 Diabetes mellitus subjects at the Department of Medicine, Isra University Hospital and Consultant Clinics Hyderabad from January 2014 to July 2014. A sample of 310 diagnosed type 2 DM were selected through non-probability purposive sampling according to inclusion and exclusion criteria. Serum 25-OH-D3 was estimated by ARCHITECT I 1000 system. Lipids sub fractions were analyzed according to standard methods. Data was analyzed on SPSS version 21.0. Data was analyzed on SPSS version 21.0. Continuous and categorical variables were analyzed by student’s t test and chi square test respectively. The associations of various lipid fractions with vitamin D3 were analyzed by Pearson’s correlation. The significant p-value was taken at ≤ 0.05. Reduced 25-hydroxyvitamin D3 levels were observed in 84.1% (n = 261). The 25-hydroxyvitamin D3 levels as low as 6ng/dl was observed in present study. The lipid profile status of subjects with normal and reduced 25-hydroxyvitamin D3 showed significant differences (p = 0.001). Triglycerides, LDLc, VLDLc, and Cholesterols exhibited an inverse correlation with 25 hydroxyvitamin D3; however a positive correlation was noted for HDL cholesterol. In conclusion, the vitamin D3 deficiency was observed in type 2 diabetic subject and showed independent association with dyslipidemia in type 2 diabetics. VL - 1 IS - 3 ER -
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