Limited Management of Systemic Erythematosus Lupus in Madagascar

Fandresena Arilala Sendrasoa; Irina Mamisoa Ranaivo; Naina Harinjara Razanakoto; Malalaniaina Andrianarison; Onivola Raharolahy; Lala Soavina Ramarozatovo; Fahafahantsoa Rapelanoro Rabenja

doi:doi:10.11648/j.ijbecs.20170304.14

Limited Management of Systemic Erythematosus Lupus in Madagascar

Fandresena Arilala Sendrasoa, Irina Mamisoa Ranaivo, Naina Harinjara Razanakoto, Malalaniaina Andrianarison, Onivola Raharolahy, Lala Soavina Ramarozatovo, Fahafahantsoa Rapelanoro Rabenja

Published in International Journal of Biomedical Engineering and Clinical Science (Volume 3, Issue 4)

Received: 31 October 2016 Accepted: 27 December 2016 Published: 24 October 2017

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Abstract

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves multiple organs and has alternating periods of flare-ups and quiescence. SLE requires multiple paraclinical and therapeutic investigations that are not accessible by Malagasy patients. We aim to assess the monthly direct cost in SLE referring to international recommendations. The cost of paraclinical exams and treatment expenses were estimated as a percentage of the MMMS (Malagasy Minimum Monthly Salary). According to international recommendations, the cost of first-line paraclinical exams for SLE diagnosis was 274,2% of the MMMS. The costs of diagnostic tests were 110,9% and 923,4% of the MMMS to research renal and neurological damage, respectively. The monthly cost of pharmacological therapies ranged from 132,2% to 205,9% of the MMMS, depending on the severity of SLE. Clinical examination and affordable paraclinical exams were fundamental in our practice to manage systemic lupus erythematosus lupus. Appropriate recommendations for emergent countries should be come up.

Published in	International Journal of Biomedical Engineering and Clinical Science (Volume 3, Issue 4)
DOI	10.11648/j.ijbecs.20170304.14
Page(s)	48-51
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Systemic Lupus Erythematosus, Cost, International Recommendations

References

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[2]	Zhu TY, Tam LS, Li EK. The socioeconomic burden of systemic lupus erythematosus: state-of-the-art and prospects. Pharmacoeconomic Outcomes Res 2012; 12: 53-69.
[3]	Cervera R, Khamashta MA, Font J et al. Morbidity and mortality in systemic lupus erythematosus during a 10-year period: A comparison of early and late manifestations in a cohort of 1000 patients. Medicine (Baltimore) 2003; 82: 299-308.
[4]	Lau CS, Mak A. The socieconomic burden of SLE. Nat Rev Rheumatol 2009; 5: 400-404.
[5]	Bertrias G, Ioannidis J. P, Boletis J, Bombardieri S, Cervera R, Dostal C et al. EULAR recommendations for the management of systemic lupus erythematosus. Report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics. Ann Rheum Dis 2008; 67: 195-205.
[6]	Mosca M, Tani C, Aringer M, Bombardieri s, Boumpas D, Brey R et al. EULAR recommendations for monitoring patients with systemic lupus erythematosus in clinical practice and in observational studies. Ann Rheum Dis 2010; 69 (7): 1269-74.
[7]	Clarke AE, Panopalis P, Petri M, Manzi S, Isenberg DA, Gordon C et al. SLE patients with renal damage incur higher health care costs. Rheumatology 2008; 47: 329-33.
[8]	Zhu TY, Tam LS, Lee VW, Lee KK, Li EK. The impact of flare on disease costs of patients with systemic lupus erythematosus. Arthritis Rheum 2009; 61: 1159-67.
[9]	Petri M, Orbai A. M, Alarcon G. S, Gordon C, Merrill J. T, Fortin P. R et al. Derivation and validation of the Systemic Lupus International Collaborating Clinics Classification Criteria for Systemic Lupus Erythematosus. Arthr Rheum 2012; 64 (8): 2677-86.
[10]	Sendrasoa F. A. Comparative analysis of acute cutaneous lupus erythematosus and chronic cutaneous lupus erythematosus. Madagascar: DEFS Memories, 2015; N°307.
[11]	Romero-Diaz J, Isenberg D, Ramsey-Goldman R. Measures of adult systemic lupus erythematosus. Arthritis Care Res 2011; 63 (11): doi: 10.1002/acr. 20572.
[12]	Hahn B. H, McMahon M. A, Wilkinson A, Wallace W. D, Daikh D. I, Fitzgerals J. D et al. American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis. Arthritis Care Res 2012; 64 (6): 797-808.
[13]	Wilson EC, Jayne DR, Dellow E, Fordham RJ. The cost-effectiveness of mycophenolate mofetil as firstline therapy in active lupus nephritis. Rheumatology 2007; 46 (7): 1096-101.
[14]	Aghdassi E, Zhang W, St-Pierre Y, Clarke AE, Morrison S, Peeva V et al. Healthcare cost and loss of productivity in a Canadian population of patients with and without lupus nephritis. J Rheumatol 2011; 38 (4): 658-66.
[15]	Zhu TY, Tam LS, Lee VW, Lee KK, Li EK. Systemic lupus erythematosus with neuropsychiatric manifestations incurs high direct costs: a cost-of-illness study in Hong Kong. Rheumatology 2009; 48 (5): 564-8.

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Fandresena Arilala Sendrasoa, Irina Mamisoa Ranaivo, Naina Harinjara Razanakoto, Malalaniaina Andrianarison, Onivola Raharolahy, et al. (2017). Limited Management of Systemic Erythematosus Lupus in Madagascar. International Journal of Biomedical Engineering and Clinical Science, 3(4), 48-51. https://doi.org/10.11648/j.ijbecs.20170304.14

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ACS Style

Fandresena Arilala Sendrasoa; Irina Mamisoa Ranaivo; Naina Harinjara Razanakoto; Malalaniaina Andrianarison; Onivola Raharolahy, et al. Limited Management of Systemic Erythematosus Lupus in Madagascar. Int. J. Biomed. Eng. Clin. Sci. 2017, 3(4), 48-51. doi: 10.11648/j.ijbecs.20170304.14

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AMA Style

Fandresena Arilala Sendrasoa, Irina Mamisoa Ranaivo, Naina Harinjara Razanakoto, Malalaniaina Andrianarison, Onivola Raharolahy, et al. Limited Management of Systemic Erythematosus Lupus in Madagascar. Int J Biomed Eng Clin Sci. 2017;3(4):48-51. doi: 10.11648/j.ijbecs.20170304.14

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@article{10.11648/j.ijbecs.20170304.14,
  author = {Fandresena Arilala Sendrasoa and Irina Mamisoa Ranaivo and Naina Harinjara Razanakoto and Malalaniaina Andrianarison and Onivola Raharolahy and Lala Soavina Ramarozatovo and Fahafahantsoa Rapelanoro Rabenja},
  title = {Limited Management of Systemic Erythematosus Lupus in Madagascar},
  journal = {International Journal of Biomedical Engineering and Clinical Science},
  volume = {3},
  number = {4},
  pages = {48-51},
  doi = {10.11648/j.ijbecs.20170304.14},
  url = {https://doi.org/10.11648/j.ijbecs.20170304.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbecs.20170304.14},
  abstract = {Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves multiple organs and has alternating periods of flare-ups and quiescence. SLE requires multiple paraclinical and therapeutic investigations that are not accessible by Malagasy patients. We aim to assess the monthly direct cost in SLE referring to international recommendations. The cost of paraclinical exams and treatment expenses were estimated as a percentage of the MMMS (Malagasy Minimum Monthly Salary). According to international recommendations, the cost of first-line paraclinical exams for SLE diagnosis was 274,2% of the MMMS. The costs of diagnostic tests were 110,9% and 923,4% of the MMMS to research renal and neurological damage, respectively. The monthly cost of pharmacological therapies ranged from 132,2% to 205,9% of the MMMS, depending on the severity of SLE. Clinical examination and affordable paraclinical exams were fundamental in our practice to manage systemic lupus erythematosus lupus. Appropriate recommendations for emergent countries should be come up.},
 year = {2017}
}

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TY  - JOUR
T1  - Limited Management of Systemic Erythematosus Lupus in Madagascar
AU  - Fandresena Arilala Sendrasoa
AU  - Irina Mamisoa Ranaivo
AU  - Naina Harinjara Razanakoto
AU  - Malalaniaina Andrianarison
AU  - Onivola Raharolahy
AU  - Lala Soavina Ramarozatovo
AU  - Fahafahantsoa Rapelanoro Rabenja
Y1  - 2017/10/24
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbecs.20170304.14
DO  - 10.11648/j.ijbecs.20170304.14
T2  - International Journal of Biomedical Engineering and Clinical Science
JF  - International Journal of Biomedical Engineering and Clinical Science
JO  - International Journal of Biomedical Engineering and Clinical Science
SP  - 48
EP  - 51
PB  - Science Publishing Group
SN  - 2472-1301
UR  - https://doi.org/10.11648/j.ijbecs.20170304.14
AB  - Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves multiple organs and has alternating periods of flare-ups and quiescence. SLE requires multiple paraclinical and therapeutic investigations that are not accessible by Malagasy patients. We aim to assess the monthly direct cost in SLE referring to international recommendations. The cost of paraclinical exams and treatment expenses were estimated as a percentage of the MMMS (Malagasy Minimum Monthly Salary). According to international recommendations, the cost of first-line paraclinical exams for SLE diagnosis was 274,2% of the MMMS. The costs of diagnostic tests were 110,9% and 923,4% of the MMMS to research renal and neurological damage, respectively. The monthly cost of pharmacological therapies ranged from 132,2% to 205,9% of the MMMS, depending on the severity of SLE. Clinical examination and affordable paraclinical exams were fundamental in our practice to manage systemic lupus erythematosus lupus. Appropriate recommendations for emergent countries should be come up.
VL  - 3
IS  - 4
ER  -

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Author Information

Fandresena Arilala Sendrasoa

Department of Dermatology, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar
Irina Mamisoa Ranaivo

Department of Dermatology, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar
Naina Harinjara Razanakoto

Department of Dermatology, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar
Malalaniaina Andrianarison

Department of Dermatology, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar
Onivola Raharolahy

Department of Dermatology, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar
Lala Soavina Ramarozatovo

Department of Dermatology, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar
Fahafahantsoa Rapelanoro Rabenja

Department of Dermatology, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar

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APA Style

Fandresena Arilala Sendrasoa, Irina Mamisoa Ranaivo, Naina Harinjara Razanakoto, Malalaniaina Andrianarison, Onivola Raharolahy, et al. (2017). Limited Management of Systemic Erythematosus Lupus in Madagascar. International Journal of Biomedical Engineering and Clinical Science, 3(4), 48-51. https://doi.org/10.11648/j.ijbecs.20170304.14

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ACS Style

Fandresena Arilala Sendrasoa; Irina Mamisoa Ranaivo; Naina Harinjara Razanakoto; Malalaniaina Andrianarison; Onivola Raharolahy, et al. Limited Management of Systemic Erythematosus Lupus in Madagascar. Int. J. Biomed. Eng. Clin. Sci. 2017, 3(4), 48-51. doi: 10.11648/j.ijbecs.20170304.14

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AMA Style

Fandresena Arilala Sendrasoa, Irina Mamisoa Ranaivo, Naina Harinjara Razanakoto, Malalaniaina Andrianarison, Onivola Raharolahy, et al. Limited Management of Systemic Erythematosus Lupus in Madagascar. Int J Biomed Eng Clin Sci. 2017;3(4):48-51. doi: 10.11648/j.ijbecs.20170304.14

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@article{10.11648/j.ijbecs.20170304.14,
  author = {Fandresena Arilala Sendrasoa and Irina Mamisoa Ranaivo and Naina Harinjara Razanakoto and Malalaniaina Andrianarison and Onivola Raharolahy and Lala Soavina Ramarozatovo and Fahafahantsoa Rapelanoro Rabenja},
  title = {Limited Management of Systemic Erythematosus Lupus in Madagascar},
  journal = {International Journal of Biomedical Engineering and Clinical Science},
  volume = {3},
  number = {4},
  pages = {48-51},
  doi = {10.11648/j.ijbecs.20170304.14},
  url = {https://doi.org/10.11648/j.ijbecs.20170304.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbecs.20170304.14},
  abstract = {Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves multiple organs and has alternating periods of flare-ups and quiescence. SLE requires multiple paraclinical and therapeutic investigations that are not accessible by Malagasy patients. We aim to assess the monthly direct cost in SLE referring to international recommendations. The cost of paraclinical exams and treatment expenses were estimated as a percentage of the MMMS (Malagasy Minimum Monthly Salary). According to international recommendations, the cost of first-line paraclinical exams for SLE diagnosis was 274,2% of the MMMS. The costs of diagnostic tests were 110,9% and 923,4% of the MMMS to research renal and neurological damage, respectively. The monthly cost of pharmacological therapies ranged from 132,2% to 205,9% of the MMMS, depending on the severity of SLE. Clinical examination and affordable paraclinical exams were fundamental in our practice to manage systemic lupus erythematosus lupus. Appropriate recommendations for emergent countries should be come up.},
 year = {2017}
}

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TY  - JOUR
T1  - Limited Management of Systemic Erythematosus Lupus in Madagascar
AU  - Fandresena Arilala Sendrasoa
AU  - Irina Mamisoa Ranaivo
AU  - Naina Harinjara Razanakoto
AU  - Malalaniaina Andrianarison
AU  - Onivola Raharolahy
AU  - Lala Soavina Ramarozatovo
AU  - Fahafahantsoa Rapelanoro Rabenja
Y1  - 2017/10/24
PY  - 2017
N1  - https://doi.org/10.11648/j.ijbecs.20170304.14
DO  - 10.11648/j.ijbecs.20170304.14
T2  - International Journal of Biomedical Engineering and Clinical Science
JF  - International Journal of Biomedical Engineering and Clinical Science
JO  - International Journal of Biomedical Engineering and Clinical Science
SP  - 48
EP  - 51
PB  - Science Publishing Group
SN  - 2472-1301
UR  - https://doi.org/10.11648/j.ijbecs.20170304.14
AB  - Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves multiple organs and has alternating periods of flare-ups and quiescence. SLE requires multiple paraclinical and therapeutic investigations that are not accessible by Malagasy patients. We aim to assess the monthly direct cost in SLE referring to international recommendations. The cost of paraclinical exams and treatment expenses were estimated as a percentage of the MMMS (Malagasy Minimum Monthly Salary). According to international recommendations, the cost of first-line paraclinical exams for SLE diagnosis was 274,2% of the MMMS. The costs of diagnostic tests were 110,9% and 923,4% of the MMMS to research renal and neurological damage, respectively. The monthly cost of pharmacological therapies ranged from 132,2% to 205,9% of the MMMS, depending on the severity of SLE. Clinical examination and affordable paraclinical exams were fundamental in our practice to manage systemic lupus erythematosus lupus. Appropriate recommendations for emergent countries should be come up.
VL  - 3
IS  - 4
ER  -

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