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Effect of Different Concentrations of Intraperitoneal Bupivacaine on Postoperative Outcome in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery

Received: 20 October 2020     Accepted: 2 November 2020     Published: 9 November 2020
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Abstract

Introduction: Regional analgesic techniques with infiltration of local anesthetic represent a cornerstone in modern postoperative pain management strategies after laparoscopic surgery. If used in a right concentration, it could help in attenuation of postoperative pain with better pulmonary performance and less morbidity. Aim: to compare the effect of different concentrations of intraperitoneal bupivacaine to obtain proper pain relief after laparoscopic bariatric surgery and evaluating its effect on pulmonary functions. Patients and methods: One hundred and twenty morbidly obese patients were included in this study. Patients were divided into three group. Group (A) patients received 50 ml bupivacaine 0.25% into the coelomic cavity. Group (B) patients receive 50 ml bupivacaine 0.125% into the coelomic cavity. Group (C) control group (n=36): patients receive 50 ml of normal saline into the coelomic cavity. VAS score and pulmonary function study were examined before and at regular intervals after surgery. Total analgesic requirements and time to first analgesic rescue was recorded. Results: VAS in group (A) was significantly lower than group (C) 2 hours after surgery and lower in group (A) compared with group (B&C) at 4 and 6 hours postoperative. Postoperative morphine consumption was lower in group (A) during the first 24 hours when compared to group (B & C) respectively. Both FVC and FEV1 were higher in group (A) compared to group (B&C) at 6hours postoperative. Conclusion: intraperitoneal injection of bupivacaine 0.25% is an efficient method of decreasing the postoperative pain with better preservation of pulmonary functions in morbidly obese patients undergoing laparoscopic bariatric surgery.

Published in International Journal of Anesthesia and Clinical Medicine (Volume 8, Issue 2)
DOI 10.11648/j.ijacm.20200802.18
Page(s) 68-73
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Analgesia, Bariatric Surgery, Pain Score, Pulmonary Functions, Recruitment Maneuvers

References
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    Mohammed Adel Hegazy, Hosam Hamed, Mohamed Said Salim, Mohamed Abdelraoof, Ahmed Mohamed Farid, et al. (2020). Effect of Different Concentrations of Intraperitoneal Bupivacaine on Postoperative Outcome in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery. International Journal of Anesthesia and Clinical Medicine, 8(2), 68-73. https://doi.org/10.11648/j.ijacm.20200802.18

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    ACS Style

    Mohammed Adel Hegazy; Hosam Hamed; Mohamed Said Salim; Mohamed Abdelraoof; Ahmed Mohamed Farid, et al. Effect of Different Concentrations of Intraperitoneal Bupivacaine on Postoperative Outcome in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery. Int. J. Anesth. Clin. Med. 2020, 8(2), 68-73. doi: 10.11648/j.ijacm.20200802.18

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    AMA Style

    Mohammed Adel Hegazy, Hosam Hamed, Mohamed Said Salim, Mohamed Abdelraoof, Ahmed Mohamed Farid, et al. Effect of Different Concentrations of Intraperitoneal Bupivacaine on Postoperative Outcome in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery. Int J Anesth Clin Med. 2020;8(2):68-73. doi: 10.11648/j.ijacm.20200802.18

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  • @article{10.11648/j.ijacm.20200802.18,
      author = {Mohammed Adel Hegazy and Hosam Hamed and Mohamed Said Salim and Mohamed Abdelraoof and Ahmed Mohamed Farid and Hani Taman},
      title = {Effect of Different Concentrations of Intraperitoneal Bupivacaine on Postoperative Outcome in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery},
      journal = {International Journal of Anesthesia and Clinical Medicine},
      volume = {8},
      number = {2},
      pages = {68-73},
      doi = {10.11648/j.ijacm.20200802.18},
      url = {https://doi.org/10.11648/j.ijacm.20200802.18},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijacm.20200802.18},
      abstract = {Introduction: Regional analgesic techniques with infiltration of local anesthetic represent a cornerstone in modern postoperative pain management strategies after laparoscopic surgery. If used in a right concentration, it could help in attenuation of postoperative pain with better pulmonary performance and less morbidity. Aim: to compare the effect of different concentrations of intraperitoneal bupivacaine to obtain proper pain relief after laparoscopic bariatric surgery and evaluating its effect on pulmonary functions. Patients and methods: One hundred and twenty morbidly obese patients were included in this study. Patients were divided into three group. Group (A) patients received 50 ml bupivacaine 0.25% into the coelomic cavity. Group (B) patients receive 50 ml bupivacaine 0.125% into the coelomic cavity. Group (C) control group (n=36): patients receive 50 ml of normal saline into the coelomic cavity. VAS score and pulmonary function study were examined before and at regular intervals after surgery. Total analgesic requirements and time to first analgesic rescue was recorded. Results: VAS in group (A) was significantly lower than group (C) 2 hours after surgery and lower in group (A) compared with group (B&C) at 4 and 6 hours postoperative. Postoperative morphine consumption was lower in group (A) during the first 24 hours when compared to group (B & C) respectively. Both FVC and FEV1 were higher in group (A) compared to group (B&C) at 6hours postoperative. Conclusion: intraperitoneal injection of bupivacaine 0.25% is an efficient method of decreasing the postoperative pain with better preservation of pulmonary functions in morbidly obese patients undergoing laparoscopic bariatric surgery.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - Effect of Different Concentrations of Intraperitoneal Bupivacaine on Postoperative Outcome in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery
    AU  - Mohammed Adel Hegazy
    AU  - Hosam Hamed
    AU  - Mohamed Said Salim
    AU  - Mohamed Abdelraoof
    AU  - Ahmed Mohamed Farid
    AU  - Hani Taman
    Y1  - 2020/11/09
    PY  - 2020
    N1  - https://doi.org/10.11648/j.ijacm.20200802.18
    DO  - 10.11648/j.ijacm.20200802.18
    T2  - International Journal of Anesthesia and Clinical Medicine
    JF  - International Journal of Anesthesia and Clinical Medicine
    JO  - International Journal of Anesthesia and Clinical Medicine
    SP  - 68
    EP  - 73
    PB  - Science Publishing Group
    SN  - 2997-2698
    UR  - https://doi.org/10.11648/j.ijacm.20200802.18
    AB  - Introduction: Regional analgesic techniques with infiltration of local anesthetic represent a cornerstone in modern postoperative pain management strategies after laparoscopic surgery. If used in a right concentration, it could help in attenuation of postoperative pain with better pulmonary performance and less morbidity. Aim: to compare the effect of different concentrations of intraperitoneal bupivacaine to obtain proper pain relief after laparoscopic bariatric surgery and evaluating its effect on pulmonary functions. Patients and methods: One hundred and twenty morbidly obese patients were included in this study. Patients were divided into three group. Group (A) patients received 50 ml bupivacaine 0.25% into the coelomic cavity. Group (B) patients receive 50 ml bupivacaine 0.125% into the coelomic cavity. Group (C) control group (n=36): patients receive 50 ml of normal saline into the coelomic cavity. VAS score and pulmonary function study were examined before and at regular intervals after surgery. Total analgesic requirements and time to first analgesic rescue was recorded. Results: VAS in group (A) was significantly lower than group (C) 2 hours after surgery and lower in group (A) compared with group (B&C) at 4 and 6 hours postoperative. Postoperative morphine consumption was lower in group (A) during the first 24 hours when compared to group (B & C) respectively. Both FVC and FEV1 were higher in group (A) compared to group (B&C) at 6hours postoperative. Conclusion: intraperitoneal injection of bupivacaine 0.25% is an efficient method of decreasing the postoperative pain with better preservation of pulmonary functions in morbidly obese patients undergoing laparoscopic bariatric surgery.
    VL  - 8
    IS  - 2
    ER  - 

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Author Information
  • Department of Anesthesia and Surgical Intensive Care, Faculty of Medicine, Mansoura University, Mansoura, Egypt

  • Department of General Surgery, Faculty of Medicine, Mansoura University, Mansoura, Egypt

  • Department of General Surgery, Faculty of Medicine, Mansoura University, Mansoura, Egypt

  • Faculty of Medicine, Mansoura University, Mansoura, Egypt

  • Department of Anesthesia and Surgical Intensive Care, Faculty of Medicine, Mansoura University, Mansoura, Egypt

  • Department of Anesthesia and Surgical Intensive Care, Faculty of Medicine, Mansoura University, Mansoura, Egypt

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