The Effect on Outcome of Adding Magnesium Sulphate to Bupivacaine in the Ultrasound-guided Supraclavicular Brachial Plexus Block Anesthesia

Ashraf Mohamed Ghali; Khalid Mohamad Awid Molokhia; Sameh Abdelkhalik Ahmed

doi:doi:10.11648/j.ijacm.20190701.13

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The Effect on Outcome of Adding Magnesium Sulphate to Bupivacaine in the Ultrasound-guided Supraclavicular Brachial Plexus Block Anesthesia

Ashraf Mohamed Ghali, Khalid Mohamad Awid Molokhia, Sameh Abdelkhalik Ahmed

Published in International Journal of Anesthesia and Clinical Medicine (Volume 7, Issue 1)

Received: 28 December 2018 Accepted: 19 February 2019 Published: 5 March 2019

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Abstract

This study evaluated the motor and sensory block durations and the postoperative analgesic effects of adding Magnesium Sulphate to Bupivacaine HCL for Ultrasound-guided supraclavicular brachial plexus block. Sixty ASA I-II patients subjected to elective forearm or hand surgery were randomly divided equally into 1 of 2 groups depending upon the local anesthesia (LA) solution used to receive either 23 mL of bupivacaine HCL 0.5% plus 2 mL normal saline (group B) or 23 mL of bupivacaine HCL 0.5% plus Magnesium Sulphate 100 mg diluted with 2mL normal saline (group BM). Motor and sensory block durations were evaluated until the return of normal motor and sensory function. The degree of pain was assessed during the surgery period and 24 hours postoperatively. The results of this study showed that Magnesium Sulphate provided significantly longer motor block duration (329.33 ± 86.54 min vs 237.46 ± 62.91 min, P = 0.001) and significantly longer sensory block duration (356.00 ± 117.02 min vs 278.00 ± 87.23 min, P = 0.005) when compared with bupivacaine alone. Furthermore, the patients in the Magnesium Sulphate group achieved significantly (P < 0.001) lower values of Visual Analogue Scale (VAS) of pain between the periods from 4 to 12 hours postoperatively. There was significantly less diclofenac consumed (mg) in the Magnesium Sulphate group. The patients in the Magnesium Sulphate group reported significantly higher rates of good sleep quality on the first postoperative night (75%) compared with the patients in the bupivacaine group (25%). Also, the patient satisfaction was significantly higher in the Magnesium Sulphate group compared with the bupivacaine group (75% vs 25%). We concluded that Magnesium Sulphate 100 mg to bupivacaine HCL extended the motor and sensory block durations, provided more effective postoperative analgesia with improvement in the sleep quality of the first postoperative night, and provided better patient satisfaction compared to bupivacaine HCL alone.

Published in	International Journal of Anesthesia and Clinical Medicine (Volume 7, Issue 1)
DOI	10.11648/j.ijacm.20190701.13
Page(s)	13-19
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Magnesium Sulphate, Supraclavicular Brachial Plexus Block Anesthesia

References

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Ashraf Mohamed Ghali, Khalid Mohamad Awid Molokhia, Sameh Abdelkhalik Ahmed. (2019). The Effect on Outcome of Adding Magnesium Sulphate to Bupivacaine in the Ultrasound-guided Supraclavicular Brachial Plexus Block Anesthesia. International Journal of Anesthesia and Clinical Medicine, 7(1), 13-19. https://doi.org/10.11648/j.ijacm.20190701.13

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Ashraf Mohamed Ghali; Khalid Mohamad Awid Molokhia; Sameh Abdelkhalik Ahmed. The Effect on Outcome of Adding Magnesium Sulphate to Bupivacaine in the Ultrasound-guided Supraclavicular Brachial Plexus Block Anesthesia. Int. J. Anesth. Clin. Med. 2019, 7(1), 13-19. doi: 10.11648/j.ijacm.20190701.13

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AMA Style

Ashraf Mohamed Ghali, Khalid Mohamad Awid Molokhia, Sameh Abdelkhalik Ahmed. The Effect on Outcome of Adding Magnesium Sulphate to Bupivacaine in the Ultrasound-guided Supraclavicular Brachial Plexus Block Anesthesia. Int J Anesth Clin Med. 2019;7(1):13-19. doi: 10.11648/j.ijacm.20190701.13

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@article{10.11648/j.ijacm.20190701.13,
  author = {Ashraf Mohamed Ghali and Khalid Mohamad Awid Molokhia and Sameh Abdelkhalik Ahmed},
  title = {The Effect on Outcome of Adding Magnesium Sulphate to Bupivacaine in the Ultrasound-guided Supraclavicular Brachial Plexus Block Anesthesia},
  journal = {International Journal of Anesthesia and Clinical Medicine},
  volume = {7},
  number = {1},
  pages = {13-19},
  doi = {10.11648/j.ijacm.20190701.13},
  url = {https://doi.org/10.11648/j.ijacm.20190701.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijacm.20190701.13},
  abstract = {This study evaluated the motor and sensory block durations and the postoperative analgesic effects of adding Magnesium Sulphate to Bupivacaine HCL for Ultrasound-guided supraclavicular brachial plexus block. Sixty ASA I-II patients subjected to elective forearm or hand surgery were randomly divided equally into 1 of 2 groups depending upon the local anesthesia (LA) solution used to receive either 23 mL of bupivacaine HCL 0.5% plus 2 mL normal saline (group B) or 23 mL of bupivacaine HCL 0.5% plus Magnesium Sulphate 100 mg diluted with 2mL normal saline (group BM). Motor and sensory block durations were evaluated until the return of normal motor and sensory function. The degree of pain was assessed during the surgery period and 24 hours postoperatively. The results of this study showed that Magnesium Sulphate provided significantly longer motor block duration (329.33 ± 86.54 min vs 237.46 ± 62.91 min, P = 0.001) and significantly longer sensory block duration (356.00 ± 117.02 min vs 278.00 ± 87.23 min, P = 0.005) when compared with bupivacaine alone. Furthermore, the patients in the Magnesium Sulphate group achieved significantly (P < 0.001) lower values of Visual Analogue Scale (VAS) of pain between the periods from 4 to 12 hours postoperatively. There was significantly less diclofenac consumed (mg) in the Magnesium Sulphate group. The patients in the Magnesium Sulphate group reported significantly higher rates of good sleep quality on the first postoperative night (75%) compared with the patients in the bupivacaine group (25%). Also, the patient satisfaction was significantly higher in the Magnesium Sulphate group compared with the bupivacaine group (75% vs 25%). We concluded that Magnesium Sulphate 100 mg to bupivacaine HCL extended the motor and sensory block durations, provided more effective postoperative analgesia with improvement in the sleep quality of the first postoperative night, and provided better patient satisfaction compared to bupivacaine HCL alone.},
 year = {2019}
}

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TY  - JOUR
T1  - The Effect on Outcome of Adding Magnesium Sulphate to Bupivacaine in the Ultrasound-guided Supraclavicular Brachial Plexus Block Anesthesia
AU  - Ashraf Mohamed Ghali
AU  - Khalid Mohamad Awid Molokhia
AU  - Sameh Abdelkhalik Ahmed
Y1  - 2019/03/05
PY  - 2019
N1  - https://doi.org/10.11648/j.ijacm.20190701.13
DO  - 10.11648/j.ijacm.20190701.13
T2  - International Journal of Anesthesia and Clinical Medicine
JF  - International Journal of Anesthesia and Clinical Medicine
JO  - International Journal of Anesthesia and Clinical Medicine
SP  - 13
EP  - 19
PB  - Science Publishing Group
SN  - 2997-2698
UR  - https://doi.org/10.11648/j.ijacm.20190701.13
AB  - This study evaluated the motor and sensory block durations and the postoperative analgesic effects of adding Magnesium Sulphate to Bupivacaine HCL for Ultrasound-guided supraclavicular brachial plexus block. Sixty ASA I-II patients subjected to elective forearm or hand surgery were randomly divided equally into 1 of 2 groups depending upon the local anesthesia (LA) solution used to receive either 23 mL of bupivacaine HCL 0.5% plus 2 mL normal saline (group B) or 23 mL of bupivacaine HCL 0.5% plus Magnesium Sulphate 100 mg diluted with 2mL normal saline (group BM). Motor and sensory block durations were evaluated until the return of normal motor and sensory function. The degree of pain was assessed during the surgery period and 24 hours postoperatively. The results of this study showed that Magnesium Sulphate provided significantly longer motor block duration (329.33 ± 86.54 min vs 237.46 ± 62.91 min, P = 0.001) and significantly longer sensory block duration (356.00 ± 117.02 min vs 278.00 ± 87.23 min, P = 0.005) when compared with bupivacaine alone. Furthermore, the patients in the Magnesium Sulphate group achieved significantly (P < 0.001) lower values of Visual Analogue Scale (VAS) of pain between the periods from 4 to 12 hours postoperatively. There was significantly less diclofenac consumed (mg) in the Magnesium Sulphate group. The patients in the Magnesium Sulphate group reported significantly higher rates of good sleep quality on the first postoperative night (75%) compared with the patients in the bupivacaine group (25%). Also, the patient satisfaction was significantly higher in the Magnesium Sulphate group compared with the bupivacaine group (75% vs 25%). We concluded that Magnesium Sulphate 100 mg to bupivacaine HCL extended the motor and sensory block durations, provided more effective postoperative analgesia with improvement in the sleep quality of the first postoperative night, and provided better patient satisfaction compared to bupivacaine HCL alone.
VL  - 7
IS  - 1
ER  -

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Author Information

Ashraf Mohamed Ghali

Department of Anesthesiology and Surgical ICU, Faculty of Medicine, Tanta University, Tanta, Egypt
Khalid Mohamad Awid Molokhia

Department of Anesthesiology and Critical Care, Nizwa Governmental Hospital, Nizwa, Oman
Sameh Abdelkhalik Ahmed

Department of Anesthesiology and Surgical ICU, Faculty of Medicine, Tanta University, Tanta, Egypt

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Ashraf Mohamed Ghali, Khalid Mohamad Awid Molokhia, Sameh Abdelkhalik Ahmed. (2019). The Effect on Outcome of Adding Magnesium Sulphate to Bupivacaine in the Ultrasound-guided Supraclavicular Brachial Plexus Block Anesthesia. International Journal of Anesthesia and Clinical Medicine, 7(1), 13-19. https://doi.org/10.11648/j.ijacm.20190701.13

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ACS Style

Ashraf Mohamed Ghali; Khalid Mohamad Awid Molokhia; Sameh Abdelkhalik Ahmed. The Effect on Outcome of Adding Magnesium Sulphate to Bupivacaine in the Ultrasound-guided Supraclavicular Brachial Plexus Block Anesthesia. Int. J. Anesth. Clin. Med. 2019, 7(1), 13-19. doi: 10.11648/j.ijacm.20190701.13

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AMA Style

Ashraf Mohamed Ghali, Khalid Mohamad Awid Molokhia, Sameh Abdelkhalik Ahmed. The Effect on Outcome of Adding Magnesium Sulphate to Bupivacaine in the Ultrasound-guided Supraclavicular Brachial Plexus Block Anesthesia. Int J Anesth Clin Med. 2019;7(1):13-19. doi: 10.11648/j.ijacm.20190701.13

Copy | Download

@article{10.11648/j.ijacm.20190701.13,
  author = {Ashraf Mohamed Ghali and Khalid Mohamad Awid Molokhia and Sameh Abdelkhalik Ahmed},
  title = {The Effect on Outcome of Adding Magnesium Sulphate to Bupivacaine in the Ultrasound-guided Supraclavicular Brachial Plexus Block Anesthesia},
  journal = {International Journal of Anesthesia and Clinical Medicine},
  volume = {7},
  number = {1},
  pages = {13-19},
  doi = {10.11648/j.ijacm.20190701.13},
  url = {https://doi.org/10.11648/j.ijacm.20190701.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijacm.20190701.13},
  abstract = {This study evaluated the motor and sensory block durations and the postoperative analgesic effects of adding Magnesium Sulphate to Bupivacaine HCL for Ultrasound-guided supraclavicular brachial plexus block. Sixty ASA I-II patients subjected to elective forearm or hand surgery were randomly divided equally into 1 of 2 groups depending upon the local anesthesia (LA) solution used to receive either 23 mL of bupivacaine HCL 0.5% plus 2 mL normal saline (group B) or 23 mL of bupivacaine HCL 0.5% plus Magnesium Sulphate 100 mg diluted with 2mL normal saline (group BM). Motor and sensory block durations were evaluated until the return of normal motor and sensory function. The degree of pain was assessed during the surgery period and 24 hours postoperatively. The results of this study showed that Magnesium Sulphate provided significantly longer motor block duration (329.33 ± 86.54 min vs 237.46 ± 62.91 min, P = 0.001) and significantly longer sensory block duration (356.00 ± 117.02 min vs 278.00 ± 87.23 min, P = 0.005) when compared with bupivacaine alone. Furthermore, the patients in the Magnesium Sulphate group achieved significantly (P < 0.001) lower values of Visual Analogue Scale (VAS) of pain between the periods from 4 to 12 hours postoperatively. There was significantly less diclofenac consumed (mg) in the Magnesium Sulphate group. The patients in the Magnesium Sulphate group reported significantly higher rates of good sleep quality on the first postoperative night (75%) compared with the patients in the bupivacaine group (25%). Also, the patient satisfaction was significantly higher in the Magnesium Sulphate group compared with the bupivacaine group (75% vs 25%). We concluded that Magnesium Sulphate 100 mg to bupivacaine HCL extended the motor and sensory block durations, provided more effective postoperative analgesia with improvement in the sleep quality of the first postoperative night, and provided better patient satisfaction compared to bupivacaine HCL alone.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - The Effect on Outcome of Adding Magnesium Sulphate to Bupivacaine in the Ultrasound-guided Supraclavicular Brachial Plexus Block Anesthesia
AU  - Ashraf Mohamed Ghali
AU  - Khalid Mohamad Awid Molokhia
AU  - Sameh Abdelkhalik Ahmed
Y1  - 2019/03/05
PY  - 2019
N1  - https://doi.org/10.11648/j.ijacm.20190701.13
DO  - 10.11648/j.ijacm.20190701.13
T2  - International Journal of Anesthesia and Clinical Medicine
JF  - International Journal of Anesthesia and Clinical Medicine
JO  - International Journal of Anesthesia and Clinical Medicine
SP  - 13
EP  - 19
PB  - Science Publishing Group
SN  - 2997-2698
UR  - https://doi.org/10.11648/j.ijacm.20190701.13
AB  - This study evaluated the motor and sensory block durations and the postoperative analgesic effects of adding Magnesium Sulphate to Bupivacaine HCL for Ultrasound-guided supraclavicular brachial plexus block. Sixty ASA I-II patients subjected to elective forearm or hand surgery were randomly divided equally into 1 of 2 groups depending upon the local anesthesia (LA) solution used to receive either 23 mL of bupivacaine HCL 0.5% plus 2 mL normal saline (group B) or 23 mL of bupivacaine HCL 0.5% plus Magnesium Sulphate 100 mg diluted with 2mL normal saline (group BM). Motor and sensory block durations were evaluated until the return of normal motor and sensory function. The degree of pain was assessed during the surgery period and 24 hours postoperatively. The results of this study showed that Magnesium Sulphate provided significantly longer motor block duration (329.33 ± 86.54 min vs 237.46 ± 62.91 min, P = 0.001) and significantly longer sensory block duration (356.00 ± 117.02 min vs 278.00 ± 87.23 min, P = 0.005) when compared with bupivacaine alone. Furthermore, the patients in the Magnesium Sulphate group achieved significantly (P < 0.001) lower values of Visual Analogue Scale (VAS) of pain between the periods from 4 to 12 hours postoperatively. There was significantly less diclofenac consumed (mg) in the Magnesium Sulphate group. The patients in the Magnesium Sulphate group reported significantly higher rates of good sleep quality on the first postoperative night (75%) compared with the patients in the bupivacaine group (25%). Also, the patient satisfaction was significantly higher in the Magnesium Sulphate group compared with the bupivacaine group (75% vs 25%). We concluded that Magnesium Sulphate 100 mg to bupivacaine HCL extended the motor and sensory block durations, provided more effective postoperative analgesia with improvement in the sleep quality of the first postoperative night, and provided better patient satisfaction compared to bupivacaine HCL alone.
VL  - 7
IS  - 1
ER  -

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