Clinical Profile of Respiratory Distress in Newborn in Chhattisgarh, India

Ashish Wanare; Pradeep Agrawal; Guruveerajeysingh Malini; Mitesh Chawda; Ganpat Jha; Ravi Pandey; Bhushan Khadse; Hitav Someshwar; Akshay Patil

doi:doi:10.11648/j.ejcbs.20200603.12

Clinical Profile of Respiratory Distress in Newborn in Chhattisgarh, India

Ashish Wanare, Pradeep Agrawal, Guruveerajeysingh Malini, Mitesh Chawda, Ganpat Jha, Ravi Pandey, Bhushan Khadse, Hitav Someshwar, Akshay Patil

Published in European Journal of Clinical and Biomedical Sciences (Volume 6, Issue 3)

Received: 13 May 2020 Accepted: 19 June 2020 Published: 10 August 2020

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Abstract

Present study was a Hospital based observational study of 100 newborns admitted in level II NICU. The study was done to assess the development of severe distress against onset, duration, oxygen requirement & outcome in terms of final diagnosis, mortality & treatment intervention. Among the 100 cases, 90% cases were of respiratory in origin. Commonest cause of respiratory distress was transient tachypnoea of newborn followed by Meconium aspiration syndrome & Respiratory distress syndrome of newborn. The onset of respiratory distress in newborn developing after 6 hours of birth & respiratory distress > 24 hours duration had severe respiratory distress. Newborn with risk factors like high maternal age, primigravida, >4 PV examinations, Meconium stained liquor and lower socioeconomic strata developed severe respiratory distress. Statistically significant correlation of severity of respiratory distress was not found with the mode of the delivery, Apgar score <7 at 1 min, gestational age of the baby, birth weight and sex of the newborn. Only neonates with RDS & MAS required ventilator care. Two of the patients of RDS required only surfactant therapy, while other two required surfactant with ventilator support. Amongst the 100 newborns with respiratory distress, mortality was in 5 newborn (5%) which includes 2 of Respiratory Distress Syndrome & 3 of Meconium Aspiration Syndrome.

Published in	European Journal of Clinical and Biomedical Sciences (Volume 6, Issue 3)
DOI	10.11648/j.ejcbs.20200603.12
Page(s)	35-42
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Respirtory Distress Syndrome, Neonates, Hylaline Membrane Disease, MAS

References

[1]	Meharban Singh, Care of the newborn 7^th edition: 273-83.
[2]	Edwards MO, Kotecha SJ, Kotecha S. Respiratory distress of the term newborn infant. Paediatric respiratory reviews. 2013 Mar 1; 14 (1): 29-37.
[3]	Hibbard JU, Wilkins I, Sun L, Gregory K, Haberman S, Hoffman M, Kominiarek MA, Reddy U, Bailit J, Branch DW, Burkman R. Respiratory morbidity in late preterm births. JAMA: the journal of the American Medical Association. 2010 Jul 28; 304 (4): 419.
[4]	Gouyon JB, Ribakovsky C, Ferdynus C, Quantin C, Sagot P, Gouyon B, Burgundy Perinatal Network. Severe respiratory disorders in term neonates. Paediatric and perinatal epidemiology. 2008 Jan; 22 (1): 22-30.
[5]	Williams O, Hutchings G, Hubinont C, Debauche C, Greenough A. Pulmonary effects of prolonged oligohydramnios following mid-trimester rupture of the membranes–antenatal and postnatal management. Neonatology. 2012; 101 (2): 83-90.
[6]	Jobe AH. Effects of chorioamnionitis on the fetal lung. Clinics in perinatology. 2012 Sep 1; 39 (3): 441-57.
[7]	Bak SY, Shin YH, Jeon JH, Park KH, Kang JH, Cha DH, Han MY, Jo HS, Lee KH, Lee CA. Prognostic factors for treatment outcomes in transient tachypnea of the newborn. Pediatrics International. 2012 Dec; 54 (6): 875-80.
[8]	Kumar A, Bhat BV. Respiratory distress in newborn. Indian Journal of Maternal and Child Health. 1996; 7 (1): 8-10.
[9]	Mathai SS, Raju U, Kanitkar M. Management of respiratory distress in the newborn. Medical journal, Armed Forces India. 2007 Jul; 63 (3): 269.
[10]	Nagendra K, Wilson CG, Ravichander B, Sood S, Singh SP: incidence and etiology of respiratory distress in newborn Medical Journal Armed Forces India. 1999 Oct; 55 (4): 331-3.
[11]	Sane SY, Patel BM. Neonatal respiratory distress syndrome: an autopsy study of 190 cases. The Indian Journal of Pediatrics. 1985 Jan 1; 52 (1): 43-6.
[12]	Angus DC, Linde-Zwirble WT, Clermont G, Griffin MF, Clark RH. Epidemiology of neonatal respiratory failure in the United States: projections from California and New York. American journal of respiratory and critical care medicine. 2001 Oct 1; 164 (7): 1154-60.
[13]	Cloherty JP, Eichenwald EC, Stark AR: Manual of neonatal care: 7^th Edition: Lippincott Williams & Wilkins; 2012.
[14]	Bhutta ZA, Yusuf K. Neonatal respiratory distress syndrome in Karachi: some epidemiological considerations. Paediatric and perinatal epidemiology. 1997 Jan; 11 (1): 37-43.
[15]	Patil AN., Sonawane S., Ahire N., Clinical Profile Of Respiratory Distress In Newborn. MVPJS. 2018 June (5) 19735.
[16]	Shrivastava SP, Kumar A, Ojha AK. Verbal autopsy determined causes of neonatal deaths. Indian pediatrics. 2001 Sep 1; 38 (9): 1022-4.
[17]	Kommawar A, Borkar R, Vagha J, Lakhkar B, Meshram R, Taksandae A. Study of respiratory distress in newborn. International Journal of Contemporary Pediatrics. 2017 Feb 22; 4 (2): 490-4.
[18]	Dani C, Reali MF, Bertini G, Wiechmann L, Spagnolo A, Tangucci M, Rubaltelli FF. Risk factors for the development of respiratory distress syndrome and transient tachypnoea in newborn infants. Italian Group of Neonatal Pneumology. European Respiratory Journal. 1999 Jul 1; 14 (1): 155-9.
[19]	Greer JJ. Current concepts on the pathogenesis and etiology of congenital diaphragmatic hernia. Respir Physiol Neurobiol. 2013; 189 (2): 232-240. Doi: 10.1016/j.resp.2013.04.015.
[20]	Mathur NB, Garg K, Kumar S. Respiratory distress in neonates with special reference to pneumonia. Indian pediatrics. 2002 Jun 27; 39 (6): 529-38.
[21]	Luerti M, Parazzini F, Agarossi A, Bianchi C, Rocchetti M, Bevilacqua G. Risk factors for respiratory distress syndrome in the newborn: a multicenter Italian survey. Acta obstetricia et gynecologica Scandinavica. 1993 Jul; 72 (5): 359-64.
[22]	Rubaltelli FF, Dani C, Reali MF, Bertini G, Wiechmann L, Tangucci M, Spagnolo A, Italian Group of Neonatal Pneumology. Acute neonatal respiratory distress in Italy: a one-year prospective study. Acta paediatrica. 1998 Dec; 87 (12): 1261-8.
[23]	Lee KS, Eidelman AI, Tseng PI, Kandail SR, Gartner LM. Respiratory distress syndrome of the newborn and complications of pregnancy. Pediatrics. 1976 Nov 1; 58 (5): 675-80.
[24]	McElhatton PR, Garbis HM, Eléfant E, Vial T, Bellemin B, Mastroiacovo P, Arnon J, Rodríguez-Pinilla E, Schaefer C, Pexieder T, Merlob P. The outcome of pregnancy in 689 women exposed to therapeutic doses of antidepressants. A collaborative study of the European Network of Teratology Information Services (ENTIS). Reproductive toxicology. 1996 Jul 1; 10 (4): 285-94.
[25]	Geller EJ, Wu JM, Jannelli ML, Nguyen TV, Visco AG. Neonatal outcomes associated with planned vaginal versus planned primary cesarean delivery. Journal of Perinatology. 2010 Apr; 30 (4): 258.
[26]	Fidanovski D, Milev V, Sajkovski A, Hristovski A, Sofijanova A, Kojić L, Kimovska M: Mortality risk factors in premature infants with respiratory distress syndrome treated by mechanical ventilation. Srp Arh Celok Lek. 2005 Jan-Feb; 133 (1-2): 29-35.
[27]	Miller H. C.: Respiratory Distress Syndrome Of Newborn Infants: Statistical Evaluation of Factors Possibly Affecting Survival of Premature Infants. Pediatrics 1998; 573-579.
[28]	Sengupta S, Carrion V, Shelton J, Wynn RJ, Ryan RM, Singhal K, Lakshminrusimha S. Adverse neonatal outcomes associated with early-term birth. JAMA pediatrics. 2013 Nov 1; 167 (11): 1053-9.

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APA Style

Ashish Wanare, Pradeep Agrawal, Guruveerajeysingh Malini, Mitesh Chawda, Ganpat Jha, et al. (2020). Clinical Profile of Respiratory Distress in Newborn in Chhattisgarh, India. European Journal of Clinical and Biomedical Sciences, 6(3), 35-42. https://doi.org/10.11648/j.ejcbs.20200603.12

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ACS Style

Ashish Wanare; Pradeep Agrawal; Guruveerajeysingh Malini; Mitesh Chawda; Ganpat Jha, et al. Clinical Profile of Respiratory Distress in Newborn in Chhattisgarh, India. Eur. J. Clin. Biomed. Sci. 2020, 6(3), 35-42. doi: 10.11648/j.ejcbs.20200603.12

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AMA Style

Ashish Wanare, Pradeep Agrawal, Guruveerajeysingh Malini, Mitesh Chawda, Ganpat Jha, et al. Clinical Profile of Respiratory Distress in Newborn in Chhattisgarh, India. Eur J Clin Biomed Sci. 2020;6(3):35-42. doi: 10.11648/j.ejcbs.20200603.12

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@article{10.11648/j.ejcbs.20200603.12,
  author = {Ashish Wanare and Pradeep Agrawal and Guruveerajeysingh Malini and Mitesh Chawda and Ganpat Jha and Ravi Pandey and Bhushan Khadse and Hitav Someshwar and Akshay Patil},
  title = {Clinical Profile of Respiratory Distress in Newborn in Chhattisgarh, India},
  journal = {European Journal of Clinical and Biomedical Sciences},
  volume = {6},
  number = {3},
  pages = {35-42},
  doi = {10.11648/j.ejcbs.20200603.12},
  url = {https://doi.org/10.11648/j.ejcbs.20200603.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20200603.12},
  abstract = {Present study was a Hospital based observational study of 100 newborns admitted in level II NICU. The study was done to assess the development of severe distress against onset, duration, oxygen requirement & outcome in terms of final diagnosis, mortality & treatment intervention. Among the 100 cases, 90% cases were of respiratory in origin. Commonest cause of respiratory distress was transient tachypnoea of newborn followed by Meconium aspiration syndrome & Respiratory distress syndrome of newborn. The onset of respiratory distress in newborn developing after 6 hours of birth & respiratory distress > 24 hours duration had severe respiratory distress. Newborn with risk factors like high maternal age, primigravida, >4 PV examinations, Meconium stained liquor and lower socioeconomic strata developed severe respiratory distress. Statistically significant correlation of severity of respiratory distress was not found with the mode of the delivery, Apgar score <7 at 1 min, gestational age of the baby, birth weight and sex of the newborn. Only neonates with RDS & MAS required ventilator care. Two of the patients of RDS required only surfactant therapy, while other two required surfactant with ventilator support. Amongst the 100 newborns with respiratory distress, mortality was in 5 newborn (5%) which includes 2 of Respiratory Distress Syndrome & 3 of Meconium Aspiration Syndrome.},
 year = {2020}
}

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TY  - JOUR
T1  - Clinical Profile of Respiratory Distress in Newborn in Chhattisgarh, India
AU  - Ashish Wanare
AU  - Pradeep Agrawal
AU  - Guruveerajeysingh Malini
AU  - Mitesh Chawda
AU  - Ganpat Jha
AU  - Ravi Pandey
AU  - Bhushan Khadse
AU  - Hitav Someshwar
AU  - Akshay Patil
Y1  - 2020/08/10
PY  - 2020
N1  - https://doi.org/10.11648/j.ejcbs.20200603.12
DO  - 10.11648/j.ejcbs.20200603.12
T2  - European Journal of Clinical and Biomedical Sciences
JF  - European Journal of Clinical and Biomedical Sciences
JO  - European Journal of Clinical and Biomedical Sciences
SP  - 35
EP  - 42
PB  - Science Publishing Group
SN  - 2575-5005
UR  - https://doi.org/10.11648/j.ejcbs.20200603.12
AB  - Present study was a Hospital based observational study of 100 newborns admitted in level II NICU. The study was done to assess the development of severe distress against onset, duration, oxygen requirement & outcome in terms of final diagnosis, mortality & treatment intervention. Among the 100 cases, 90% cases were of respiratory in origin. Commonest cause of respiratory distress was transient tachypnoea of newborn followed by Meconium aspiration syndrome & Respiratory distress syndrome of newborn. The onset of respiratory distress in newborn developing after 6 hours of birth & respiratory distress > 24 hours duration had severe respiratory distress. Newborn with risk factors like high maternal age, primigravida, >4 PV examinations, Meconium stained liquor and lower socioeconomic strata developed severe respiratory distress. Statistically significant correlation of severity of respiratory distress was not found with the mode of the delivery, Apgar score <7 at 1 min, gestational age of the baby, birth weight and sex of the newborn. Only neonates with RDS & MAS required ventilator care. Two of the patients of RDS required only surfactant therapy, while other two required surfactant with ventilator support. Amongst the 100 newborns with respiratory distress, mortality was in 5 newborn (5%) which includes 2 of Respiratory Distress Syndrome & 3 of Meconium Aspiration Syndrome.
VL  - 6
IS  - 3
ER  -

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Author Information

Ashish Wanare

Department of Paediatrics, Jawaharlal Nehru Hospital & Research Center, Bhilai, Chhattisgarh, India
Pradeep Agrawal

Department of Paediatrics, Jawaharlal Nehru Hospital & Research Center, Bhilai, Chhattisgarh, India
Guruveerajeysingh Malini

Department of Paediatrics, Jawaharlal Nehru Hospital & Research Center, Bhilai, Chhattisgarh, India
Mitesh Chawda

Department of Paediatrics, Jawaharlal Nehru Hospital & Research Center, Bhilai, Chhattisgarh, India
Ganpat Jha

Department of Paediatrics, Jawaharlal Nehru Hospital & Research Center, Bhilai, Chhattisgarh, India
Ravi Pandey

Department of Paediatrics, Jawaharlal Nehru Hospital & Research Center, Bhilai, Chhattisgarh, India
Bhushan Khadse

Department of Radiology, Jawaharlal Nehru Hospital & Research Center, Bhilai, Chhattisgarh, India
Hitav Someshwar

Department of Neurophysiotherapy, KJ Somaiya College of Physiotherapy, Mumbai, Maharashtra, India
Akshay Patil

Departmnet of Paediatrics, Dr. Vasantrao Pawar Medical College and Hospital, Nashik, Maharashtra, India

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APA Style

Ashish Wanare, Pradeep Agrawal, Guruveerajeysingh Malini, Mitesh Chawda, Ganpat Jha, et al. (2020). Clinical Profile of Respiratory Distress in Newborn in Chhattisgarh, India. European Journal of Clinical and Biomedical Sciences, 6(3), 35-42. https://doi.org/10.11648/j.ejcbs.20200603.12

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ACS Style

Ashish Wanare; Pradeep Agrawal; Guruveerajeysingh Malini; Mitesh Chawda; Ganpat Jha, et al. Clinical Profile of Respiratory Distress in Newborn in Chhattisgarh, India. Eur. J. Clin. Biomed. Sci. 2020, 6(3), 35-42. doi: 10.11648/j.ejcbs.20200603.12

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AMA Style

Ashish Wanare, Pradeep Agrawal, Guruveerajeysingh Malini, Mitesh Chawda, Ganpat Jha, et al. Clinical Profile of Respiratory Distress in Newborn in Chhattisgarh, India. Eur J Clin Biomed Sci. 2020;6(3):35-42. doi: 10.11648/j.ejcbs.20200603.12

Copy | Download

@article{10.11648/j.ejcbs.20200603.12,
  author = {Ashish Wanare and Pradeep Agrawal and Guruveerajeysingh Malini and Mitesh Chawda and Ganpat Jha and Ravi Pandey and Bhushan Khadse and Hitav Someshwar and Akshay Patil},
  title = {Clinical Profile of Respiratory Distress in Newborn in Chhattisgarh, India},
  journal = {European Journal of Clinical and Biomedical Sciences},
  volume = {6},
  number = {3},
  pages = {35-42},
  doi = {10.11648/j.ejcbs.20200603.12},
  url = {https://doi.org/10.11648/j.ejcbs.20200603.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20200603.12},
  abstract = {Present study was a Hospital based observational study of 100 newborns admitted in level II NICU. The study was done to assess the development of severe distress against onset, duration, oxygen requirement & outcome in terms of final diagnosis, mortality & treatment intervention. Among the 100 cases, 90% cases were of respiratory in origin. Commonest cause of respiratory distress was transient tachypnoea of newborn followed by Meconium aspiration syndrome & Respiratory distress syndrome of newborn. The onset of respiratory distress in newborn developing after 6 hours of birth & respiratory distress > 24 hours duration had severe respiratory distress. Newborn with risk factors like high maternal age, primigravida, >4 PV examinations, Meconium stained liquor and lower socioeconomic strata developed severe respiratory distress. Statistically significant correlation of severity of respiratory distress was not found with the mode of the delivery, Apgar score <7 at 1 min, gestational age of the baby, birth weight and sex of the newborn. Only neonates with RDS & MAS required ventilator care. Two of the patients of RDS required only surfactant therapy, while other two required surfactant with ventilator support. Amongst the 100 newborns with respiratory distress, mortality was in 5 newborn (5%) which includes 2 of Respiratory Distress Syndrome & 3 of Meconium Aspiration Syndrome.},
 year = {2020}
}

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TY  - JOUR
T1  - Clinical Profile of Respiratory Distress in Newborn in Chhattisgarh, India
AU  - Ashish Wanare
AU  - Pradeep Agrawal
AU  - Guruveerajeysingh Malini
AU  - Mitesh Chawda
AU  - Ganpat Jha
AU  - Ravi Pandey
AU  - Bhushan Khadse
AU  - Hitav Someshwar
AU  - Akshay Patil
Y1  - 2020/08/10
PY  - 2020
N1  - https://doi.org/10.11648/j.ejcbs.20200603.12
DO  - 10.11648/j.ejcbs.20200603.12
T2  - European Journal of Clinical and Biomedical Sciences
JF  - European Journal of Clinical and Biomedical Sciences
JO  - European Journal of Clinical and Biomedical Sciences
SP  - 35
EP  - 42
PB  - Science Publishing Group
SN  - 2575-5005
UR  - https://doi.org/10.11648/j.ejcbs.20200603.12
AB  - Present study was a Hospital based observational study of 100 newborns admitted in level II NICU. The study was done to assess the development of severe distress against onset, duration, oxygen requirement & outcome in terms of final diagnosis, mortality & treatment intervention. Among the 100 cases, 90% cases were of respiratory in origin. Commonest cause of respiratory distress was transient tachypnoea of newborn followed by Meconium aspiration syndrome & Respiratory distress syndrome of newborn. The onset of respiratory distress in newborn developing after 6 hours of birth & respiratory distress > 24 hours duration had severe respiratory distress. Newborn with risk factors like high maternal age, primigravida, >4 PV examinations, Meconium stained liquor and lower socioeconomic strata developed severe respiratory distress. Statistically significant correlation of severity of respiratory distress was not found with the mode of the delivery, Apgar score <7 at 1 min, gestational age of the baby, birth weight and sex of the newborn. Only neonates with RDS & MAS required ventilator care. Two of the patients of RDS required only surfactant therapy, while other two required surfactant with ventilator support. Amongst the 100 newborns with respiratory distress, mortality was in 5 newborn (5%) which includes 2 of Respiratory Distress Syndrome & 3 of Meconium Aspiration Syndrome.
VL  - 6
IS  - 3
ER  -

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