Albumin and Serum Vitamin A Status of Malnourished Children

Egbe Edmund Richard; Eworo Raymond Ekong

doi:doi:10.11648/j.ejcbs.20180401.12

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Albumin and Serum Vitamin A Status of Malnourished Children

Egbe Edmund Richard, Eworo Raymond Ekong

Published in European Journal of Clinical and Biomedical Sciences (Volume 4, Issue 1)

Received: 26 November 2017 Accepted: 14 December 2017 Published: 23 March 2018

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Abstract

Malnutrition remains a major health problem in the third world countries, and is a key factor to the high death rate among children below five years old. This study aimed to determine serum vitamin A, mid-upper arm circumference (MUAC), and albumin levels of malnourished children and their well-fed counterparts. A total of one hundred (100) children comprising of fifty (50) malnourished children under the age of five years and fifty (50) well-fed age-matched children were recruited into this study. Mid upper arm circumference (MUAC) measurement was used to categorize the children into malnourished and the well-fed groups. The malnourished were further classified into kwashiorkor and marasmic cohorts. Serum vitamin A and albumin levels were determined by colorimetric methods. Data were analyzed using SPSS version 20.0 statistical package, differences between and variations among groups were determined by Student’s t-test and ANOVA respectively while the association between variables by Pearson’s correlation. Differences were considered statistically significant at p≤0.05. Serum vitamin A, MUAC and albumin levels of the well-fed group were significantly higher (p<0.05) than those of the malnourished. Comparing the well-fed, the kwashiorkor and the marasmic groups, the mean serum vitamin A, MUAC and albumin of the well-fed were significantly higher (p=0.001) than those of the kwashiorkor and marasmic groups. Mean albumin level of the kwashiorkor was significantly lower (p<0.05) than that of marasmic group. Mean MUAC of the kwashiorkor subjects was significantly higher (p<0.05) than that of the marasmic subjects. Serum vitamin A was not significantly different (p=0.724) between the kwashiorkor and the marasmic groups. In the marasmic subjects mean serum vitamin A correlates negatively with albumin (r= -0.517, p=0.011). In the kwashiorkor subjects, serum vitamin A correlates negatively with albumin (r=-0.080, p=0.690). In the well-fed children, serum vitamin A correlates positively with albumin (r=0.340, p=0.016). Conclusion: malnourished children with kwashiorkor and marasmus have lower albumin, serum vitamin A and MUAC compared with the well-fed children.

Published in	European Journal of Clinical and Biomedical Sciences (Volume 4, Issue 1)
DOI	10.11648/j.ejcbs.20180401.12
Page(s)	6-11
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Albumin, Vitamin A, MUAC, Malnutrition, Children

References

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Egbe Edmund Richard, Eworo Raymond Ekong. (2018). Albumin and Serum Vitamin A Status of Malnourished Children. European Journal of Clinical and Biomedical Sciences, 4(1), 6-11. https://doi.org/10.11648/j.ejcbs.20180401.12

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Egbe Edmund Richard; Eworo Raymond Ekong. Albumin and Serum Vitamin A Status of Malnourished Children. Eur. J. Clin. Biomed. Sci. 2018, 4(1), 6-11. doi: 10.11648/j.ejcbs.20180401.12

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AMA Style

Egbe Edmund Richard, Eworo Raymond Ekong. Albumin and Serum Vitamin A Status of Malnourished Children. Eur J Clin Biomed Sci. 2018;4(1):6-11. doi: 10.11648/j.ejcbs.20180401.12

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@article{10.11648/j.ejcbs.20180401.12,
  author = {Egbe Edmund Richard and Eworo Raymond Ekong},
  title = {Albumin and Serum Vitamin A Status of Malnourished Children},
  journal = {European Journal of Clinical and Biomedical Sciences},
  volume = {4},
  number = {1},
  pages = {6-11},
  doi = {10.11648/j.ejcbs.20180401.12},
  url = {https://doi.org/10.11648/j.ejcbs.20180401.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20180401.12},
  abstract = {Malnutrition remains a major health problem in the third world countries, and is a key factor to the high death rate among children below five years old. This study aimed to determine serum vitamin A, mid-upper arm circumference (MUAC), and albumin levels of malnourished children and their well-fed counterparts. A total of one hundred (100) children comprising of fifty (50) malnourished children under the age of five years and fifty (50) well-fed age-matched children were recruited into this study. Mid upper arm circumference (MUAC) measurement was used to categorize the children into malnourished and the well-fed groups. The malnourished were further classified into kwashiorkor and marasmic cohorts. Serum vitamin A and albumin levels were determined by colorimetric methods. Data were analyzed using SPSS version 20.0 statistical package, differences between and variations among groups were determined by Student’s t-test and ANOVA respectively while the association between variables by Pearson’s correlation. Differences were considered statistically significant at p≤0.05. Serum vitamin A, MUAC and albumin levels of the well-fed group were significantly higher (p<0.05) than those of the malnourished. Comparing the well-fed, the kwashiorkor and the marasmic groups, the mean serum vitamin A, MUAC and albumin of the well-fed were significantly higher (p=0.001) than those of the kwashiorkor and marasmic groups. Mean albumin level of the kwashiorkor was significantly lower (p<0.05) than that of marasmic group. Mean MUAC of the kwashiorkor subjects was significantly higher (p<0.05) than that of the marasmic subjects. Serum vitamin A was not significantly different (p=0.724) between the kwashiorkor and the marasmic groups. In the marasmic subjects mean serum vitamin A correlates negatively with albumin (r= -0.517, p=0.011). In the kwashiorkor subjects, serum vitamin A correlates negatively with albumin (r=-0.080, p=0.690). In the well-fed children, serum vitamin A correlates positively with albumin (r=0.340, p=0.016). Conclusion: malnourished children with kwashiorkor and marasmus have lower albumin, serum vitamin A and MUAC compared with the well-fed children.},
 year = {2018}
}

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TY - JOUR
T1 - Albumin and Serum Vitamin A Status of Malnourished Children
AU - Egbe Edmund Richard
AU - Eworo Raymond Ekong
Y1 - 2018/03/23
PY - 2018
N1 - https://doi.org/10.11648/j.ejcbs.20180401.12
DO - 10.11648/j.ejcbs.20180401.12
T2 - European Journal of Clinical and Biomedical Sciences
JF - European Journal of Clinical and Biomedical Sciences
JO - European Journal of Clinical and Biomedical Sciences
SP - 6
EP - 11
PB - Science Publishing Group
SN - 2575-5005
UR - https://doi.org/10.11648/j.ejcbs.20180401.12
AB - Malnutrition remains a major health problem in the third world countries, and is a key factor to the high death rate among children below five years old. This study aimed to determine serum vitamin A, mid-upper arm circumference (MUAC), and albumin levels of malnourished children and their well-fed counterparts. A total of one hundred (100) children comprising of fifty (50) malnourished children under the age of five years and fifty (50) well-fed age-matched children were recruited into this study. Mid upper arm circumference (MUAC) measurement was used to categorize the children into malnourished and the well-fed groups. The malnourished were further classified into kwashiorkor and marasmic cohorts. Serum vitamin A and albumin levels were determined by colorimetric methods. Data were analyzed using SPSS version 20.0 statistical package, differences between and variations among groups were determined by Student’s t-test and ANOVA respectively while the association between variables by Pearson’s correlation. Differences were considered statistically significant at p≤0.05. Serum vitamin A, MUAC and albumin levels of the well-fed group were significantly higher (p<0.05) than those of the malnourished. Comparing the well-fed, the kwashiorkor and the marasmic groups, the mean serum vitamin A, MUAC and albumin of the well-fed were significantly higher (p=0.001) than those of the kwashiorkor and marasmic groups. Mean albumin level of the kwashiorkor was significantly lower (p<0.05) than that of marasmic group. Mean MUAC of the kwashiorkor subjects was significantly higher (p<0.05) than that of the marasmic subjects. Serum vitamin A was not significantly different (p=0.724) between the kwashiorkor and the marasmic groups. In the marasmic subjects mean serum vitamin A correlates negatively with albumin (r= -0.517, p=0.011). In the kwashiorkor subjects, serum vitamin A correlates negatively with albumin (r=-0.080, p=0.690). In the well-fed children, serum vitamin A correlates positively with albumin (r=0.340, p=0.016). Conclusion: malnourished children with kwashiorkor and marasmus have lower albumin, serum vitamin A and MUAC compared with the well-fed children.
VL - 4
IS - 1
ER -

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Egbe Edmund Richard

Department of Medical Laboratory Science, University of Calabar, Calabar, Nigeria
Eworo Raymond Ekong

Department of Medical Laboratory Science, University of Calabar, Calabar, Nigeria

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Egbe Edmund Richard, Eworo Raymond Ekong. (2018). Albumin and Serum Vitamin A Status of Malnourished Children. European Journal of Clinical and Biomedical Sciences, 4(1), 6-11. https://doi.org/10.11648/j.ejcbs.20180401.12

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Egbe Edmund Richard; Eworo Raymond Ekong. Albumin and Serum Vitamin A Status of Malnourished Children. Eur. J. Clin. Biomed. Sci. 2018, 4(1), 6-11. doi: 10.11648/j.ejcbs.20180401.12

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AMA Style

Egbe Edmund Richard, Eworo Raymond Ekong. Albumin and Serum Vitamin A Status of Malnourished Children. Eur J Clin Biomed Sci. 2018;4(1):6-11. doi: 10.11648/j.ejcbs.20180401.12

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@article{10.11648/j.ejcbs.20180401.12,
  author = {Egbe Edmund Richard and Eworo Raymond Ekong},
  title = {Albumin and Serum Vitamin A Status of Malnourished Children},
  journal = {European Journal of Clinical and Biomedical Sciences},
  volume = {4},
  number = {1},
  pages = {6-11},
  doi = {10.11648/j.ejcbs.20180401.12},
  url = {https://doi.org/10.11648/j.ejcbs.20180401.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20180401.12},
  abstract = {Malnutrition remains a major health problem in the third world countries, and is a key factor to the high death rate among children below five years old. This study aimed to determine serum vitamin A, mid-upper arm circumference (MUAC), and albumin levels of malnourished children and their well-fed counterparts. A total of one hundred (100) children comprising of fifty (50) malnourished children under the age of five years and fifty (50) well-fed age-matched children were recruited into this study. Mid upper arm circumference (MUAC) measurement was used to categorize the children into malnourished and the well-fed groups. The malnourished were further classified into kwashiorkor and marasmic cohorts. Serum vitamin A and albumin levels were determined by colorimetric methods. Data were analyzed using SPSS version 20.0 statistical package, differences between and variations among groups were determined by Student’s t-test and ANOVA respectively while the association between variables by Pearson’s correlation. Differences were considered statistically significant at p≤0.05. Serum vitamin A, MUAC and albumin levels of the well-fed group were significantly higher (p<0.05) than those of the malnourished. Comparing the well-fed, the kwashiorkor and the marasmic groups, the mean serum vitamin A, MUAC and albumin of the well-fed were significantly higher (p=0.001) than those of the kwashiorkor and marasmic groups. Mean albumin level of the kwashiorkor was significantly lower (p<0.05) than that of marasmic group. Mean MUAC of the kwashiorkor subjects was significantly higher (p<0.05) than that of the marasmic subjects. Serum vitamin A was not significantly different (p=0.724) between the kwashiorkor and the marasmic groups. In the marasmic subjects mean serum vitamin A correlates negatively with albumin (r= -0.517, p=0.011). In the kwashiorkor subjects, serum vitamin A correlates negatively with albumin (r=-0.080, p=0.690). In the well-fed children, serum vitamin A correlates positively with albumin (r=0.340, p=0.016). Conclusion: malnourished children with kwashiorkor and marasmus have lower albumin, serum vitamin A and MUAC compared with the well-fed children.},
 year = {2018}
}

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