Assessment of Some Haemostatic Parameters Among Diabetes Mellitus Patients in Bayelsa State: A Case Study at the Federal Medical Centre, Yenagoa

Benjamin Onyema Eledo; Michael Ifesinachi Nwoga; Okezie Caleb Okamgba; Sylvester Chibueze Izah

doi:doi:10.11648/j.ejcbs.20170305.12

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Assessment of Some Haemostatic Parameters Among Diabetes Mellitus Patients in Bayelsa State: A Case Study at the Federal Medical Centre, Yenagoa

Benjamin Onyema Eledo, Michael Ifesinachi Nwoga, Okezie Caleb Okamgba, Sylvester Chibueze Izah

Published in European Journal of Clinical and Biomedical Sciences (Volume 3, Issue 5)

Received: 13 August 2017 Accepted: 5 September 2017 Published: 6 October 2017

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Abstract

Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels. This study investigated some haemostatic parameters among diabetes mellitus patients attending diabetes clinic at the Federal Medical Centre Yenagoa; A tertiary health institution. One hundred and eleven individuals participated in this study, comprising 31 females and 25 males (diabetes mellitus patients) and 30 females and 25 males (control subjects). Blood was collected from the participants and the prothrombin time, activated partial thromboplastin time and platelets count were analyzed using standard procedures. Results showed mean values in females and males as 10.84±2.18 and11.28±0.86seconds respectively (prothrombin time), 29.26±2.16 and 30.93±2.43seconds (activated partial thromboplastin time), 401.94±59.20 and 402.20±41.72x10⁹/L respectively (platelets counts) for the diabetes mellitus patients and 12.74±1.42 and 12.34±1.09seconds respectively (prothrombin time), 32.81±1.76 and 32.77±1.46seconds (activated partial thromboplastin time), 263.33±55.32 and 282±51.03 x10⁹/L respectively (platelets counts) for the control groups. There was significant variation (P<0.002) among both group of subjects for each of the sex. Prothrombin time and activated partial thromboplastin time were significantly lower while platelets counts were significantly higher in the diabetes mellitus patients compared to the control. Lower prothrombin time and activated partial thromboplastin time suggest hyper-coagulability which may lead to adverse cardiovascular and thrombotic complications among the diabetes mellitus patients. While an elevated platelets counts is an indication of increased platelets function which could lead to vascular complications.

Published in	European Journal of Clinical and Biomedical Sciences (Volume 3, Issue 5)
DOI	10.11648/j.ejcbs.20170305.12
Page(s)	91-96
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Diabetics, Haemostatic Parameters, Prothrombin Time, Activated Partial Thromboplastin Time, Platelets Counts

References

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APA Style

Benjamin Onyema Eledo, Michael Ifesinachi Nwoga, Okezie Caleb Okamgba, Sylvester Chibueze Izah. (2017). Assessment of Some Haemostatic Parameters Among Diabetes Mellitus Patients in Bayelsa State: A Case Study at the Federal Medical Centre, Yenagoa. European Journal of Clinical and Biomedical Sciences, 3(5), 91-96. https://doi.org/10.11648/j.ejcbs.20170305.12

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ACS Style

Benjamin Onyema Eledo; Michael Ifesinachi Nwoga; Okezie Caleb Okamgba; Sylvester Chibueze Izah. Assessment of Some Haemostatic Parameters Among Diabetes Mellitus Patients in Bayelsa State: A Case Study at the Federal Medical Centre, Yenagoa. Eur. J. Clin. Biomed. Sci. 2017, 3(5), 91-96. doi: 10.11648/j.ejcbs.20170305.12

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AMA Style

Benjamin Onyema Eledo, Michael Ifesinachi Nwoga, Okezie Caleb Okamgba, Sylvester Chibueze Izah. Assessment of Some Haemostatic Parameters Among Diabetes Mellitus Patients in Bayelsa State: A Case Study at the Federal Medical Centre, Yenagoa. Eur J Clin Biomed Sci. 2017;3(5):91-96. doi: 10.11648/j.ejcbs.20170305.12

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@article{10.11648/j.ejcbs.20170305.12,
  author = {Benjamin Onyema Eledo and Michael Ifesinachi Nwoga and Okezie Caleb Okamgba and Sylvester Chibueze Izah},
  title = {Assessment of Some Haemostatic Parameters Among Diabetes Mellitus Patients in Bayelsa State: A Case Study at the Federal Medical Centre, Yenagoa},
  journal = {European Journal of Clinical and Biomedical Sciences},
  volume = {3},
  number = {5},
  pages = {91-96},
  doi = {10.11648/j.ejcbs.20170305.12},
  url = {https://doi.org/10.11648/j.ejcbs.20170305.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20170305.12},
  abstract = {Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels. This study investigated some haemostatic parameters among diabetes mellitus patients attending diabetes clinic at the Federal Medical Centre Yenagoa; A tertiary health institution. One hundred and eleven individuals participated in this study, comprising 31 females and 25 males (diabetes mellitus patients) and 30 females and 25 males (control subjects). Blood was collected from the participants and the prothrombin time, activated partial thromboplastin time and platelets count were analyzed using standard procedures. Results showed mean values in females and males as 10.84±2.18 and11.28±0.86seconds respectively (prothrombin time), 29.26±2.16 and 30.93±2.43seconds (activated partial thromboplastin time), 401.94±59.20 and 402.20±41.72x109/L respectively (platelets counts) for the diabetes mellitus patients and 12.74±1.42 and 12.34±1.09seconds respectively (prothrombin time), 32.81±1.76 and 32.77±1.46seconds (activated partial thromboplastin time), 263.33±55.32 and 282±51.03 x109/L respectively (platelets counts) for the control groups. There was significant variation (P<0.002) among both group of subjects for each of the sex. Prothrombin time and activated partial thromboplastin time were significantly lower while platelets counts were significantly higher in the diabetes mellitus patients compared to the control. Lower prothrombin time and activated partial thromboplastin time suggest hyper-coagulability which may lead to adverse cardiovascular and thrombotic complications among the diabetes mellitus patients. While an elevated platelets counts is an indication of increased platelets function which could lead to vascular complications.},
 year = {2017}
}

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TY  - JOUR
T1  - Assessment of Some Haemostatic Parameters Among Diabetes Mellitus Patients in Bayelsa State: A Case Study at the Federal Medical Centre, Yenagoa
AU  - Benjamin Onyema Eledo
AU  - Michael Ifesinachi Nwoga
AU  - Okezie Caleb Okamgba
AU  - Sylvester Chibueze Izah
Y1  - 2017/10/06
PY  - 2017
N1  - https://doi.org/10.11648/j.ejcbs.20170305.12
DO  - 10.11648/j.ejcbs.20170305.12
T2  - European Journal of Clinical and Biomedical Sciences
JF  - European Journal of Clinical and Biomedical Sciences
JO  - European Journal of Clinical and Biomedical Sciences
SP  - 91
EP  - 96
PB  - Science Publishing Group
SN  - 2575-5005
UR  - https://doi.org/10.11648/j.ejcbs.20170305.12
AB  - Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels. This study investigated some haemostatic parameters among diabetes mellitus patients attending diabetes clinic at the Federal Medical Centre Yenagoa; A tertiary health institution. One hundred and eleven individuals participated in this study, comprising 31 females and 25 males (diabetes mellitus patients) and 30 females and 25 males (control subjects). Blood was collected from the participants and the prothrombin time, activated partial thromboplastin time and platelets count were analyzed using standard procedures. Results showed mean values in females and males as 10.84±2.18 and11.28±0.86seconds respectively (prothrombin time), 29.26±2.16 and 30.93±2.43seconds (activated partial thromboplastin time), 401.94±59.20 and 402.20±41.72x109/L respectively (platelets counts) for the diabetes mellitus patients and 12.74±1.42 and 12.34±1.09seconds respectively (prothrombin time), 32.81±1.76 and 32.77±1.46seconds (activated partial thromboplastin time), 263.33±55.32 and 282±51.03 x109/L respectively (platelets counts) for the control groups. There was significant variation (P<0.002) among both group of subjects for each of the sex. Prothrombin time and activated partial thromboplastin time were significantly lower while platelets counts were significantly higher in the diabetes mellitus patients compared to the control. Lower prothrombin time and activated partial thromboplastin time suggest hyper-coagulability which may lead to adverse cardiovascular and thrombotic complications among the diabetes mellitus patients. While an elevated platelets counts is an indication of increased platelets function which could lead to vascular complications.
VL  - 3
IS  - 5
ER  -

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Author Information

Benjamin Onyema Eledo

Department of Medical Laboratory Science, Faculty of Health Sciences, Madonna University, Nigeria, Elele
Michael Ifesinachi Nwoga

Department of Medical Laboratory Science, Faculty of Health Sciences, Madonna University, Nigeria, Elele
Okezie Caleb Okamgba

Department of Medical Laboratory Science, Abia State University, Uturu, Nigeri
Sylvester Chibueze Izah

Department of Biological Sciences, Faculty of Science, Niger Delta University, Wilberforce Island, Nigeria

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Benjamin Onyema Eledo, Michael Ifesinachi Nwoga, Okezie Caleb Okamgba, Sylvester Chibueze Izah. (2017). Assessment of Some Haemostatic Parameters Among Diabetes Mellitus Patients in Bayelsa State: A Case Study at the Federal Medical Centre, Yenagoa. European Journal of Clinical and Biomedical Sciences, 3(5), 91-96. https://doi.org/10.11648/j.ejcbs.20170305.12

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ACS Style

Benjamin Onyema Eledo; Michael Ifesinachi Nwoga; Okezie Caleb Okamgba; Sylvester Chibueze Izah. Assessment of Some Haemostatic Parameters Among Diabetes Mellitus Patients in Bayelsa State: A Case Study at the Federal Medical Centre, Yenagoa. Eur. J. Clin. Biomed. Sci. 2017, 3(5), 91-96. doi: 10.11648/j.ejcbs.20170305.12

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AMA Style

Benjamin Onyema Eledo, Michael Ifesinachi Nwoga, Okezie Caleb Okamgba, Sylvester Chibueze Izah. Assessment of Some Haemostatic Parameters Among Diabetes Mellitus Patients in Bayelsa State: A Case Study at the Federal Medical Centre, Yenagoa. Eur J Clin Biomed Sci. 2017;3(5):91-96. doi: 10.11648/j.ejcbs.20170305.12

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@article{10.11648/j.ejcbs.20170305.12,
  author = {Benjamin Onyema Eledo and Michael Ifesinachi Nwoga and Okezie Caleb Okamgba and Sylvester Chibueze Izah},
  title = {Assessment of Some Haemostatic Parameters Among Diabetes Mellitus Patients in Bayelsa State: A Case Study at the Federal Medical Centre, Yenagoa},
  journal = {European Journal of Clinical and Biomedical Sciences},
  volume = {3},
  number = {5},
  pages = {91-96},
  doi = {10.11648/j.ejcbs.20170305.12},
  url = {https://doi.org/10.11648/j.ejcbs.20170305.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20170305.12},
  abstract = {Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels. This study investigated some haemostatic parameters among diabetes mellitus patients attending diabetes clinic at the Federal Medical Centre Yenagoa; A tertiary health institution. One hundred and eleven individuals participated in this study, comprising 31 females and 25 males (diabetes mellitus patients) and 30 females and 25 males (control subjects). Blood was collected from the participants and the prothrombin time, activated partial thromboplastin time and platelets count were analyzed using standard procedures. Results showed mean values in females and males as 10.84±2.18 and11.28±0.86seconds respectively (prothrombin time), 29.26±2.16 and 30.93±2.43seconds (activated partial thromboplastin time), 401.94±59.20 and 402.20±41.72x109/L respectively (platelets counts) for the diabetes mellitus patients and 12.74±1.42 and 12.34±1.09seconds respectively (prothrombin time), 32.81±1.76 and 32.77±1.46seconds (activated partial thromboplastin time), 263.33±55.32 and 282±51.03 x109/L respectively (platelets counts) for the control groups. There was significant variation (P<0.002) among both group of subjects for each of the sex. Prothrombin time and activated partial thromboplastin time were significantly lower while platelets counts were significantly higher in the diabetes mellitus patients compared to the control. Lower prothrombin time and activated partial thromboplastin time suggest hyper-coagulability which may lead to adverse cardiovascular and thrombotic complications among the diabetes mellitus patients. While an elevated platelets counts is an indication of increased platelets function which could lead to vascular complications.},
 year = {2017}
}

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TY  - JOUR
T1  - Assessment of Some Haemostatic Parameters Among Diabetes Mellitus Patients in Bayelsa State: A Case Study at the Federal Medical Centre, Yenagoa
AU  - Benjamin Onyema Eledo
AU  - Michael Ifesinachi Nwoga
AU  - Okezie Caleb Okamgba
AU  - Sylvester Chibueze Izah
Y1  - 2017/10/06
PY  - 2017
N1  - https://doi.org/10.11648/j.ejcbs.20170305.12
DO  - 10.11648/j.ejcbs.20170305.12
T2  - European Journal of Clinical and Biomedical Sciences
JF  - European Journal of Clinical and Biomedical Sciences
JO  - European Journal of Clinical and Biomedical Sciences
SP  - 91
EP  - 96
PB  - Science Publishing Group
SN  - 2575-5005
UR  - https://doi.org/10.11648/j.ejcbs.20170305.12
AB  - Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels. This study investigated some haemostatic parameters among diabetes mellitus patients attending diabetes clinic at the Federal Medical Centre Yenagoa; A tertiary health institution. One hundred and eleven individuals participated in this study, comprising 31 females and 25 males (diabetes mellitus patients) and 30 females and 25 males (control subjects). Blood was collected from the participants and the prothrombin time, activated partial thromboplastin time and platelets count were analyzed using standard procedures. Results showed mean values in females and males as 10.84±2.18 and11.28±0.86seconds respectively (prothrombin time), 29.26±2.16 and 30.93±2.43seconds (activated partial thromboplastin time), 401.94±59.20 and 402.20±41.72x109/L respectively (platelets counts) for the diabetes mellitus patients and 12.74±1.42 and 12.34±1.09seconds respectively (prothrombin time), 32.81±1.76 and 32.77±1.46seconds (activated partial thromboplastin time), 263.33±55.32 and 282±51.03 x109/L respectively (platelets counts) for the control groups. There was significant variation (P<0.002) among both group of subjects for each of the sex. Prothrombin time and activated partial thromboplastin time were significantly lower while platelets counts were significantly higher in the diabetes mellitus patients compared to the control. Lower prothrombin time and activated partial thromboplastin time suggest hyper-coagulability which may lead to adverse cardiovascular and thrombotic complications among the diabetes mellitus patients. While an elevated platelets counts is an indication of increased platelets function which could lead to vascular complications.
VL  - 3
IS  - 5
ER  -

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