| Peer-Reviewed

Gender Differences in Types and Frequencies of Coronary Artery Anomalies and Myocardial Bridge in 10,457 Chinese Undergoing 320-Slice Computed Tomography

Received: 8 September 2016     Accepted: 12 October 2016     Published: 28 October 2016
Views:       Downloads:
Abstract

Varied frequencies of coronary artery anomalies (CAAs) and myocardial bridge (MB) exist in previous studies. Race and gender may play a role. The present study aimed to investigate the gender differences in types and frequencies of coronary artery anomalies (CAAs) and myocardial bridge (MB) in Chinese undergoing 320-slice coronary computed tomography. The authors assessed prospectively the records of 10,457 consecutive patients who underwent 320-slice coronary computed tomography for any reason. CAAs were divided into 4 groups: 1) Anomalies of origination; 2) Anomalies of intrinsic coronary arterial anatomy; 3) fistula; 4) Number anomalies. Clinical relevance based classifications of CAAs (Class I-Benign; II-Relevant; III-Severe; IV-Critical) were also presented. Types and frequencies of CAAs and MB were compared between males and females. The overall prevalence of CAAs was 2.60% in our study, involving 0.62% of anomalies of origination, 1.72% of anomalies of intrinsic coronary arterial anatomy, 0.23% of fistula, and 0.04% of number anomalies. Gender differences were not presented in the frequencies of the majority of CAAs (p>0.05). However, males were more likely to have LCX originating from the right sinus of Valsalva when compared with females (0.11% vs. 0.01%, p=0.027). There was no difference of clinical relevance based classifications of CAAs between males and females (p>0.05). The prevalence of MB was 33.15% (3466/10,475) in total. Higher frequency (19.13% vs. 14.0%, p<0.001) and longer average length (16.89±8.58mm vs. 13.71±8.50mm, p<0.001) of MB were observed in males than those in females; while the distribution and the mean depth of MB were similar in males and females (p>0.05). In conclusion, LCX originating from the right sinus of Valsalva and MB with longer average length occurred more frequently in Chinese males than females.

Published in European Journal of Clinical and Biomedical Sciences (Volume 2, Issue 3)
DOI 10.11648/j.ejcbs.20160203.11
Page(s) 14-22
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Computed Tomography Angiography, Coronary Artery Anomaly, Myocardial Bridge, Fistula, Coronary Hypoplasia

References
[1] Villa AD, Sammut E, Nair A, Rajani R, Bonamini R, Chiribiri A. Coronary artery anomalies overview: The normal and the abnormal. World J Radiol 2016; 8: 537-555.
[2] Akpinar I, Sayin MR, Karabag T, Gursoy YC, Kucuk E, Kiran S, et al. Differences in sex, angiographic frequency, and parameters in patients with coronary artery anomalies: single-center screening of 25368 patients by coronary angiography. Coron Artery Dis 2013; 24: 266-271.
[3] Xiong W, He D, Lu C, Qin X, Li H, Xu X, et al. Coronary artery anomalies: the left main coronary artery or left anterior descending coronary artery originating from the proximal of right coronary artery. Chin Med J. 2014; 127: 2392-2394.
[4] Gräni C, Benz DC, Schmied C, Vontobel J, Possner M, Clerc OF, et al. Prevalence and characteristics of coronary artery anomalies detected by coronary computed tomography angiography in 5 634 consecutive patients in a single centre in Switzerland. Swiss Med Wkly 2016; 146: w14294.
[5] Zhang LJ, Yang GF, Huang W, Zhou CS, Chen P, Lu GM. Anomalous origin of coronary artery in 1879 Chinese adults on dual-source CT angiography. Neth Heart J 2010: 18: 466-470.
[6] Safak O, Gursul E, Yesil M, Tuluce SY, Arikan ME, Ozyildirim S, et al. Prevalence of coronary artery anomalies in patients undergoing coronary artery angiography: a review of 16768 patients. A retrospective, single-center study. Minerva Cardioangiol 2015; 63: 113-20.
[7] Cheng Z, Wang X, Duan Y, Wu L, Wu D, Liang C, et al. Detection of coronary artery anomalies by dual-source CT coronary angiography. Clin Radiol 2010; 65: 815-822.
[8] Namgung J, Kim JA. The prevalence of coronary anomalies in a single center of Korea: origination, course, and termination anomaliesof aberrant coronary arteries detected by ECG-gated cardiac MDCT. BMC Cardiovasc Disord 2014; 14: 48.
[9] Zeina AR, Odeh M, Blinder J, Rosenschein U, Barmeir E. Myocardial bridge: evaluation on MDCT. Am J Roentgenol 2007; 188: 1069-1073.
[10] Liu SH, Yang Q, Chen JH, Wang XM, Wang M, Liu C. Myocardial bridging on dual-source computed tomography: degree of systolic compression of mural coronary artery correlating with length and depth of the myocardial bridge. Clin Imaging 2010; 34: 83-88.
[11] Barriales Villa R, Moris C, Lopez Muniz A, Hernández LC, San Román L, Barriales Alvarez V, et al. Adult congenital anomalies of the coronary arteries described over 31 years of angiographic studies in the Asturias Principality: main angiographic and clinical characteristics. Rev Esp Cardiol 2001; 54: 269-81.
[12] Diez JD, Angelini P, Lee VV. Does the anomalous congenital origin of a coronary artery predispose to the development of stenotic atherosclerotic lesions in its proximal segment? Circulation 1997; 96 [suppl]: I-154.
[13] Austen WG, Edwards JE, Frye RL, Gensini GG, Gott VL, Griffith LS, et al. A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation 1975; 51 [suppl]: 5-40.
[14] Angelini P. Normal and anomalous coronary arteries: definitions and classification. Am Heart J 1989; 117: 418-434.
[15] Rigatelli G. Coronary artery anomalies: what we know and what we have to learn. A proposal for a new clinical classification. Ital Heart J 2003; 4: 305-310.
[16] Kawawa Y, Ishikawa Y, Gomi T, Nagamoto M, Terada H, Ishii T, et al. Detection of myocardial bridge and evaluation of its anatomical properties by coronary multislice spiral computed tomography. Eur J Radiol 2007; 61: 130-138.
[17] De Giorgio F, Abbate A, Stigliano E, Capelli A, Arena V. Hypoplastic coronary artery disease causing sudden death. Report of two cases and review of the literature. Cardiovasc Pathol 2010; 19: e107-111.
[18] Aydar Y, Yazici HU, Birdane A, Ulus T, Nadir A, Nasifov M, et al. Relationship between hypoplastic right coronary artery and coronary artery anomalies. Eur Rev Med Pharmacol Sci 2013; 17: 694-700.
[19] Levin DC, Fellows KE, Abrams HL. Hemodynamically significant primary anomalies of the coronary arteries. Angiographic aspects. Circulation 1978; 58: 25-34.
[20] Zenooz NA, Habibi R, Mammen L, Finn JP, Gilkeson RC. Coronary artery fistulas: CT findings. Radiographics 2009; 29: 781-789.
[21] Alegria JR, Herrmann J, Holmes DRJ, Lerman A, Rihal CS. Myocardial bridging. Eur Heart J 2005; 26: 1159-1168.
[22] Goo HW. CT radiation dose optimization and estimation: an update for radiologists. Korean J Radiol. 2012; 13: 1-11.
[23] Li S, Liu J, Peng L, Wu H, Wang C, Ni Q, et al. Contrast volume reduction adapted to body mass index for 320-slice coronary computed tomography angiography: Results from four-year clinical routine at a single center. Int J Cardiol 2014; 172: e140-142.
[24] Matsutani H, Sano T, Kondo T, Fujimoto S, Sekine T, Arai T, et al. Comparison of radiation dose reduction of prospective ECG-gated one beat scan using 320 area detector CT coronary angiography and prospective ECG-gated helical scan with high helical pitch (FlashScan) using 64 multidetector-row CT coronary angiography. Nihon Hoshasen Gijutsu Gakkai Zasshi 2010; 66: 1548-1554.
Cite This Article
  • APA Style

    Suhua Li, Xixiang Tang, Yanting Luo, Long Peng, Yunyue Zhao, et al. (2016). Gender Differences in Types and Frequencies of Coronary Artery Anomalies and Myocardial Bridge in 10,457 Chinese Undergoing 320-Slice Computed Tomography. European Journal of Clinical and Biomedical Sciences, 2(3), 14-22. https://doi.org/10.11648/j.ejcbs.20160203.11

    Copy | Download

    ACS Style

    Suhua Li; Xixiang Tang; Yanting Luo; Long Peng; Yunyue Zhao, et al. Gender Differences in Types and Frequencies of Coronary Artery Anomalies and Myocardial Bridge in 10,457 Chinese Undergoing 320-Slice Computed Tomography. Eur. J. Clin. Biomed. Sci. 2016, 2(3), 14-22. doi: 10.11648/j.ejcbs.20160203.11

    Copy | Download

    AMA Style

    Suhua Li, Xixiang Tang, Yanting Luo, Long Peng, Yunyue Zhao, et al. Gender Differences in Types and Frequencies of Coronary Artery Anomalies and Myocardial Bridge in 10,457 Chinese Undergoing 320-Slice Computed Tomography. Eur J Clin Biomed Sci. 2016;2(3):14-22. doi: 10.11648/j.ejcbs.20160203.11

    Copy | Download

  • @article{10.11648/j.ejcbs.20160203.11,
      author = {Suhua Li and Xixiang Tang and Yanting Luo and Long Peng and Yunyue Zhao and Jieming Zhu and Lin Chen and Ruimin Dong and Yanming Chen and Jinlai Liu},
      title = {Gender Differences in Types and Frequencies of Coronary Artery Anomalies and Myocardial Bridge in 10,457 Chinese Undergoing 320-Slice Computed Tomography},
      journal = {European Journal of Clinical and Biomedical Sciences},
      volume = {2},
      number = {3},
      pages = {14-22},
      doi = {10.11648/j.ejcbs.20160203.11},
      url = {https://doi.org/10.11648/j.ejcbs.20160203.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejcbs.20160203.11},
      abstract = {Varied frequencies of coronary artery anomalies (CAAs) and myocardial bridge (MB) exist in previous studies. Race and gender may play a role. The present study aimed to investigate the gender differences in types and frequencies of coronary artery anomalies (CAAs) and myocardial bridge (MB) in Chinese undergoing 320-slice coronary computed tomography. The authors assessed prospectively the records of 10,457 consecutive patients who underwent 320-slice coronary computed tomography for any reason. CAAs were divided into 4 groups: 1) Anomalies of origination; 2) Anomalies of intrinsic coronary arterial anatomy; 3) fistula; 4) Number anomalies. Clinical relevance based classifications of CAAs (Class I-Benign; II-Relevant; III-Severe; IV-Critical) were also presented. Types and frequencies of CAAs and MB were compared between males and females. The overall prevalence of CAAs was 2.60% in our study, involving 0.62% of anomalies of origination, 1.72% of anomalies of intrinsic coronary arterial anatomy, 0.23% of fistula, and 0.04% of number anomalies. Gender differences were not presented in the frequencies of the majority of CAAs (p>0.05). However, males were more likely to have LCX originating from the right sinus of Valsalva when compared with females (0.11% vs. 0.01%, p=0.027). There was no difference of clinical relevance based classifications of CAAs between males and females (p>0.05). The prevalence of MB was 33.15% (3466/10,475) in total. Higher frequency (19.13% vs. 14.0%, p0.05). In conclusion, LCX originating from the right sinus of Valsalva and MB with longer average length occurred more frequently in Chinese males than females.},
     year = {2016}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Gender Differences in Types and Frequencies of Coronary Artery Anomalies and Myocardial Bridge in 10,457 Chinese Undergoing 320-Slice Computed Tomography
    AU  - Suhua Li
    AU  - Xixiang Tang
    AU  - Yanting Luo
    AU  - Long Peng
    AU  - Yunyue Zhao
    AU  - Jieming Zhu
    AU  - Lin Chen
    AU  - Ruimin Dong
    AU  - Yanming Chen
    AU  - Jinlai Liu
    Y1  - 2016/10/28
    PY  - 2016
    N1  - https://doi.org/10.11648/j.ejcbs.20160203.11
    DO  - 10.11648/j.ejcbs.20160203.11
    T2  - European Journal of Clinical and Biomedical Sciences
    JF  - European Journal of Clinical and Biomedical Sciences
    JO  - European Journal of Clinical and Biomedical Sciences
    SP  - 14
    EP  - 22
    PB  - Science Publishing Group
    SN  - 2575-5005
    UR  - https://doi.org/10.11648/j.ejcbs.20160203.11
    AB  - Varied frequencies of coronary artery anomalies (CAAs) and myocardial bridge (MB) exist in previous studies. Race and gender may play a role. The present study aimed to investigate the gender differences in types and frequencies of coronary artery anomalies (CAAs) and myocardial bridge (MB) in Chinese undergoing 320-slice coronary computed tomography. The authors assessed prospectively the records of 10,457 consecutive patients who underwent 320-slice coronary computed tomography for any reason. CAAs were divided into 4 groups: 1) Anomalies of origination; 2) Anomalies of intrinsic coronary arterial anatomy; 3) fistula; 4) Number anomalies. Clinical relevance based classifications of CAAs (Class I-Benign; II-Relevant; III-Severe; IV-Critical) were also presented. Types and frequencies of CAAs and MB were compared between males and females. The overall prevalence of CAAs was 2.60% in our study, involving 0.62% of anomalies of origination, 1.72% of anomalies of intrinsic coronary arterial anatomy, 0.23% of fistula, and 0.04% of number anomalies. Gender differences were not presented in the frequencies of the majority of CAAs (p>0.05). However, males were more likely to have LCX originating from the right sinus of Valsalva when compared with females (0.11% vs. 0.01%, p=0.027). There was no difference of clinical relevance based classifications of CAAs between males and females (p>0.05). The prevalence of MB was 33.15% (3466/10,475) in total. Higher frequency (19.13% vs. 14.0%, p0.05). In conclusion, LCX originating from the right sinus of Valsalva and MB with longer average length occurred more frequently in Chinese males than females.
    VL  - 2
    IS  - 3
    ER  - 

    Copy | Download

Author Information
  • Department of Cardiology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

  • Advanced Medical Center, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

  • Department of Cardiology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

  • Department of Cardiology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

  • Department of Cardiology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

  • Department of Cardiology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

  • Department of Cardiology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

  • Department of Cardiology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

  • Advanced Medical Center, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

  • Department of Cardiology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

  • Sections