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Profile of Polycythemia Vera in Campus Teaching Hospital of Lome - Togo

Received: 29 January 2016     Accepted: 8 February 2016     Published: 29 February 2016
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Abstract

Objective: To describe the clinical, epidemiological and biological profile of polycythemia vera. Patients and methods: This is a descriptive study done from May to October 2014 witch included 13 patient who had been treated since 2007 at Campus Teaching Hospital of Lomé for polycythemia vera. The research of JAK2 V617Fmutation by PCR was been done inmolecular biologylaboratory of the Henri Mondor Hospital at Creteil in France. Results: The annual prevalence of polycythemia vera is about 2.16 new cases. The average age of patients was 46, 7 years with ranges from 31 to 65 years. There were 9 men and 4 women. The most frequent factor of finding was the fortuitous ones (23%). Most clinical signs represented were headache (69.2%), skin érythroses (53.8%) and paresthesia (30.8%). The average value of hemoglobin, hematocrit, the number of white blood cells and platelets in our patients with polycythemia who had positive JAK2V617F was respectively: 198g/L ± 44; 62.7 ± 4.4%; 9.8 G/L ± 4.3, 630.4G /l ± 367.4. Those Who didn’t had JAK2mutation, had respectively: 179g/L ± 13.3; 59,0% ± 13.3; 7.5G/L ± 4.2 GB and 441.0G /L ± 564.7. Conclusion: The JAK2V617F mutation had an interestin polycythemia vera value in diagnosis and can be systematic even in Sub-Saharan African.

Published in Cancer Research Journal (Volume 4, Issue 1)
DOI 10.11648/j.crj.20160401.13
Page(s) 24-27
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Polycythemia Vera, JAK 2 Changes, Lome (Togo)

References
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Cite This Article
  • APA Style

    Padaro Essohana, Kueviakoe Irenee Messanh Delagnon, Layibo Yao, Kolou Malewe, Agbetiafa Kossi, et al. (2016). Profile of Polycythemia Vera in Campus Teaching Hospital of Lome - Togo. Cancer Research Journal, 4(1), 24-27. https://doi.org/10.11648/j.crj.20160401.13

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    ACS Style

    Padaro Essohana; Kueviakoe Irenee Messanh Delagnon; Layibo Yao; Kolou Malewe; Agbetiafa Kossi, et al. Profile of Polycythemia Vera in Campus Teaching Hospital of Lome - Togo. Cancer Res. J. 2016, 4(1), 24-27. doi: 10.11648/j.crj.20160401.13

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    AMA Style

    Padaro Essohana, Kueviakoe Irenee Messanh Delagnon, Layibo Yao, Kolou Malewe, Agbetiafa Kossi, et al. Profile of Polycythemia Vera in Campus Teaching Hospital of Lome - Togo. Cancer Res J. 2016;4(1):24-27. doi: 10.11648/j.crj.20160401.13

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  • @article{10.11648/j.crj.20160401.13,
      author = {Padaro Essohana and Kueviakoe Irenee Messanh Delagnon and Layibo Yao and Kolou Malewe and Agbetiafa Kossi and Stephane Giraudier and Segbena Akuete Yvon},
      title = {Profile of Polycythemia Vera in Campus Teaching Hospital of Lome - Togo},
      journal = {Cancer Research Journal},
      volume = {4},
      number = {1},
      pages = {24-27},
      doi = {10.11648/j.crj.20160401.13},
      url = {https://doi.org/10.11648/j.crj.20160401.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20160401.13},
      abstract = {Objective: To describe the clinical, epidemiological and biological profile of polycythemia vera. Patients and methods: This is a descriptive study done from May to October 2014 witch included 13 patient who had been treated since 2007 at Campus Teaching Hospital of Lomé for polycythemia vera. The research of JAK2 V617Fmutation by PCR was been done inmolecular biologylaboratory of the Henri Mondor Hospital at Creteil in France. Results: The annual prevalence of polycythemia vera is about 2.16 new cases. The average age of patients was 46, 7 years with ranges from 31 to 65 years. There were 9 men and 4 women. The most frequent factor of finding was the fortuitous ones (23%). Most clinical signs represented were headache (69.2%), skin érythroses (53.8%) and paresthesia (30.8%). The average value of hemoglobin, hematocrit, the number of white blood cells and platelets in our patients with polycythemia who had positive JAK2V617F was respectively: 198g/L ± 44; 62.7 ± 4.4%; 9.8 G/L ± 4.3, 630.4G /l ± 367.4. Those Who didn’t had JAK2mutation, had respectively: 179g/L ± 13.3; 59,0% ± 13.3; 7.5G/L ± 4.2 GB and 441.0G /L ± 564.7. Conclusion: The JAK2V617F mutation had an interestin polycythemia vera value in diagnosis and can be systematic even in Sub-Saharan African.},
     year = {2016}
    }
    

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  • TY  - JOUR
    T1  - Profile of Polycythemia Vera in Campus Teaching Hospital of Lome - Togo
    AU  - Padaro Essohana
    AU  - Kueviakoe Irenee Messanh Delagnon
    AU  - Layibo Yao
    AU  - Kolou Malewe
    AU  - Agbetiafa Kossi
    AU  - Stephane Giraudier
    AU  - Segbena Akuete Yvon
    Y1  - 2016/02/29
    PY  - 2016
    N1  - https://doi.org/10.11648/j.crj.20160401.13
    DO  - 10.11648/j.crj.20160401.13
    T2  - Cancer Research Journal
    JF  - Cancer Research Journal
    JO  - Cancer Research Journal
    SP  - 24
    EP  - 27
    PB  - Science Publishing Group
    SN  - 2330-8214
    UR  - https://doi.org/10.11648/j.crj.20160401.13
    AB  - Objective: To describe the clinical, epidemiological and biological profile of polycythemia vera. Patients and methods: This is a descriptive study done from May to October 2014 witch included 13 patient who had been treated since 2007 at Campus Teaching Hospital of Lomé for polycythemia vera. The research of JAK2 V617Fmutation by PCR was been done inmolecular biologylaboratory of the Henri Mondor Hospital at Creteil in France. Results: The annual prevalence of polycythemia vera is about 2.16 new cases. The average age of patients was 46, 7 years with ranges from 31 to 65 years. There were 9 men and 4 women. The most frequent factor of finding was the fortuitous ones (23%). Most clinical signs represented were headache (69.2%), skin érythroses (53.8%) and paresthesia (30.8%). The average value of hemoglobin, hematocrit, the number of white blood cells and platelets in our patients with polycythemia who had positive JAK2V617F was respectively: 198g/L ± 44; 62.7 ± 4.4%; 9.8 G/L ± 4.3, 630.4G /l ± 367.4. Those Who didn’t had JAK2mutation, had respectively: 179g/L ± 13.3; 59,0% ± 13.3; 7.5G/L ± 4.2 GB and 441.0G /L ± 564.7. Conclusion: The JAK2V617F mutation had an interestin polycythemia vera value in diagnosis and can be systematic even in Sub-Saharan African.
    VL  - 4
    IS  - 1
    ER  - 

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Author Information
  • Hematology, Campus Teaching Hospital of Lome, Lome, Togo

  • Hematology, Campus Teaching Hospital of Lome, Lome, Togo

  • Hematology, Campus Teaching Hospital of Lome, Lome, Togo

  • Hematology, Campus Teaching Hospital of Lome, Lome, Togo

  • Hematology, Campus Teaching Hospital of Lome, Lome, Togo

  • Biological Hematology Service, APHP Henri Mondor, University Paris XII, Creteil, France

  • Hematology, Campus Teaching Hospital of Lome, Lome, Togo

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