Epilepsy and cerebrovascular accident (stroke) are two common conditions in neurology, the frequency of which increases with age. One of the most common comorbidities after a stroke is epilepsy; nearly 10% of stroke patients will have a seizure immediately or later. The aim of study was to describe the epidemiological, clinical, electrical and evolutionary aspects of post-stroke crises at the Brazzaville University Hospital. This was a cross-sectional study carried out from March 1 to September 30, 2018 in the neurology department of the University Hospital of Brazzaville. It focused on patients over 18 years of age hospitalized for a seizure following a stroke documented by imaging. The epidemiological, electroclinical and therapeutic variables were evaluated. 322 patients hospitalized for stroke, 62 (15.5%) presented with seizures following the vascular event. Men were more affected (57%). The median time to onset of seizures was 2478 days (6.8 years) after stroke. These attacks were early in 69.4% of cases, and most often focal (37.1%). The epileptic seizures were related to the arterial infarctions in 79% of the cases and the abnormalities found on the EEG tracing were consistent with the location of the vascular lesion in 63.6% of the cases. The death rate was 14.5%. The predictive factors of this mortality were: the late onset of epileptic seizures (p=0.048), the presence of hyperglycemia (p=0.006) and the absence of a return to a normal state of consciousness (p<0.001). Post-stroke epileptic seizures are frequent in our region. Secondary prevention of stroke would help reduce the occurrence of strokes and therefore epileptic seizures
Published in | Clinical Neurology and Neuroscience (Volume 4, Issue 3) |
DOI | 10.11648/j.cnn.20200403.15 |
Page(s) | 66-70 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2020. Published by Science Publishing Group |
Epileptic Seizures, Stroke, Brazzaville University Hospital
[1] | Loiseau J, Loiseau P, Duché B, Guyot M, Dartigues JF, Aublet B. À survey of epilepticdisorders in southwest France: seizures in elderly patients. Ann Neurol 1990; 27: 232-7. |
[2] | Ettinger AB, Shinnar S. New-onset seizures in an elderly hospitalized population. Neurology 1993; 43: 489-92. |
[3] | Hauser, W. A., Annegers, J. F. and Kurland, L. T. (1996) Incidence of Epilepsy and Unprovoked Seizures in Rochester, Minnesota: 1935-1984. Epilepsia, 34, 453-468. https://doi.org/10.1111/j.1528-1157.1993.tb02586.x. |
[4] | Passero S, Rocchi R, Rossi S, Ulivelli M, Vatti G. Seizures after spontaneous supratentorial intracerebral hemorrhage. Epilepsia 2002; 43: 1175–80. |
[5] | Lamy C. Epilepsie et accident vasculaire cérébral. RevNeurol 2008; 164: 841-5. |
[6] | So EL, Annegers JF, Hauser WA, O'Brien PC, Whisnant JP. Population-based study of seizures disorder after cerebral infarction. Neurology 1996; 46: 350-5. |
[7] | Bladin CF, Alexandrov AV, Bellavance A, et al. Seizures after stroke, a prospective study. Archneurol 2000; 57: 1617-22. |
[8] | Adoukonou T, Accrombessi D, Agbétou M, et al. Incidence de l’épilepsie après un accident vasculaire cérébral à Parakou en 2014. Pan Afr Med J 2019; 32: 69. |
[9] | Al mansouri, Abdel Barea. Epilepsie et crise épilpeptique post-accident vasculaire cérébral. Etude retrospective d’une série de 50 cas. [En ligne]. http://ao.um5s.ac.ma/Xmlui/handle/ 123456789/1366. 2016. |
[10] | Callixte Kuate-Tegueu, Jacques Doumbe, Estelle Joëlle Kammegne-Younang, Gustave Noubissi, Vincent de Paul Djientcheu. Les Épilepsies du Sujet âgé: Aspects épidémiologiques dans deux Centres de Santé Urbains de la Ville de Douala (Cameroun). Health Sci. Dis: Vol 16 (2) April – May – June 2015. |
[11] | Labovitz DL, Hauser WA, Sacco RL. Prevalence and predictors of early seizure and status epilepticus after first stroke. Neurology 2001; 57: 200–6. |
[12] | Napon C, Dabilgou A, Kyelem J, et al. Post-stroke epilepsy in Burkina Faso West Africa. JNS 2016; 368: 47-8 |
[13] | Gnonlonfoun DD, Adjien C, Agbetou M, et al. Post-Stroke Epilepsy within a Teaching Hospital in Cotonou, Benin. Neuroscience et Medecine 2017; 8: 47-52. |
[14] | Burn J, Dennis M, Bamford J, Sandercock P, Wade D, Warlow C. Epileptic seizures after a first stroke: the Oxfordshire community stroke project. BMJ 1997; 315: 1582–7. |
[15] | Daou Mariam. L’épilepsie du sujet âgé de 50 ans et plus dans le service de neurologie du CHU Gabriel Toure. Thèse de Médecine, 2012-2013. |
[16] | Japhari Nyassinde, Daniel Gams Massi, Kamadore Toure, Ibrahima Mariam Diallo, Ndiaye Moustapha, Amadou Gallo Diop, Mouhamadou Mansour Ndiaye. Épidémiologie des epilepsies vasculaires à la clinique de neurologie de Fann-Dakar. Revue neurologique 1 7 3 S (2017) S36–S80. |
[17] | Vercueil L. Crises d'épilepsie, épilepsies et accidents vasculaires cérébraux. Presse Med 2007; 36: 176-81. |
[18] | Millogo A. Diagnostic et prise en charge des épilepsies secondaires aux AVC. Revue Neurologique 2017; 173: S189-S190. |
[19] | Berges S, Moulin T, Berger E et al. Seizures and epilepsy following strokes: recurrence factors. Eur Neurol 2000; 43: 3-8. |
[20] | Camilo O, Goldstein LB. Seizures and epilepsy after ischemic stroke. Stroke 2004; 35: 1769-75. |
[21] | Mahoungou Guimbi Mahoungou-Guimbi KC, Ellenga Mbolla BF, Damba Banzouzi BY, Ossou Nguiet PM, Soussa RG. Prise en charge en réanimation des accidents vasculaires cérébraux hémorragiques. RevAfrAnesth Méd Urg. 2012: 50-55. |
[22] | Butzkueven H, Evans AH, Pitman A, Leopold C, Jolley DJ, Kaye AH, et al. Onset seizures independently predict poor outcome after subarachnoid hemorrhage. Neurology 2000; 55: 1315–20. |
[23] | Vespa PM, O’Phelan K, Shah M, Mirabelli J, Starkman S, Kidwell C, et al. Acute seizures after intracerebral hemorrhage: a factor in progressive midline shift and outcome. Neurology 2003; 60: 1441–6. |
[24] | Gnonlonfoun D, Adjien C, Kerekou A, Ossou-Nguiet P. M, Agbetou M, Adoukonou T, Houinato D, Avode D. G. Hyperglycémie à la phase aiguë des AVC au CNHU-HKM de Cotonou (BENIN). Revue du CAMES-Série A 2012; 13 (1): 59-62. |
[25] | Touré K, Sawadogo AA, Sow A, Basse A, Diagne NS, Diop MS, et al. Mortalité des patients hospitalisés pour AVC ischémique en neurologie au CHU Fann à Dakar. NPG 2017, 17 (100): 230-4. |
[26] | Kouame-Assouan AE, Kouassi KL, Tanoh AC, Karidioula A, Gnazegbo A, Douayoua-Sonan T. Facteurs de mortalité des AVC au CHU d’Abidjan. 2017, 173 (2): S190. |
APA Style
Sounga Bandzouzi Prince Eliot Galieni, Mpandzou Ghislain Armel, Ebelebe Evence Vital, Sounga Dufeil, Mialoudama Karl, et al. (2020). Post-Stroke Epileptic Crises: Profile of Patients at Brazzaville Chu. Clinical Neurology and Neuroscience, 4(3), 66-70. https://doi.org/10.11648/j.cnn.20200403.15
ACS Style
Sounga Bandzouzi Prince Eliot Galieni; Mpandzou Ghislain Armel; Ebelebe Evence Vital; Sounga Dufeil; Mialoudama Karl, et al. Post-Stroke Epileptic Crises: Profile of Patients at Brazzaville Chu. Clin. Neurol. Neurosci. 2020, 4(3), 66-70. doi: 10.11648/j.cnn.20200403.15
AMA Style
Sounga Bandzouzi Prince Eliot Galieni, Mpandzou Ghislain Armel, Ebelebe Evence Vital, Sounga Dufeil, Mialoudama Karl, et al. Post-Stroke Epileptic Crises: Profile of Patients at Brazzaville Chu. Clin Neurol Neurosci. 2020;4(3):66-70. doi: 10.11648/j.cnn.20200403.15
@article{10.11648/j.cnn.20200403.15, author = {Sounga Bandzouzi Prince Eliot Galieni and Mpandzou Ghislain Armel and Ebelebe Evence Vital and Sounga Dufeil and Mialoudama Karl and Motoula Latou Dina Happhia and Diatewa Josue and Matali Edgard and Obondzo Aloba Karen and Koubemba Godefroy Charles and Ossou-Nguiet Paul Macaire}, title = {Post-Stroke Epileptic Crises: Profile of Patients at Brazzaville Chu}, journal = {Clinical Neurology and Neuroscience}, volume = {4}, number = {3}, pages = {66-70}, doi = {10.11648/j.cnn.20200403.15}, url = {https://doi.org/10.11648/j.cnn.20200403.15}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20200403.15}, abstract = {Epilepsy and cerebrovascular accident (stroke) are two common conditions in neurology, the frequency of which increases with age. One of the most common comorbidities after a stroke is epilepsy; nearly 10% of stroke patients will have a seizure immediately or later. The aim of study was to describe the epidemiological, clinical, electrical and evolutionary aspects of post-stroke crises at the Brazzaville University Hospital. This was a cross-sectional study carried out from March 1 to September 30, 2018 in the neurology department of the University Hospital of Brazzaville. It focused on patients over 18 years of age hospitalized for a seizure following a stroke documented by imaging. The epidemiological, electroclinical and therapeutic variables were evaluated. 322 patients hospitalized for stroke, 62 (15.5%) presented with seizures following the vascular event. Men were more affected (57%). The median time to onset of seizures was 2478 days (6.8 years) after stroke. These attacks were early in 69.4% of cases, and most often focal (37.1%). The epileptic seizures were related to the arterial infarctions in 79% of the cases and the abnormalities found on the EEG tracing were consistent with the location of the vascular lesion in 63.6% of the cases. The death rate was 14.5%. The predictive factors of this mortality were: the late onset of epileptic seizures (p=0.048), the presence of hyperglycemia (p=0.006) and the absence of a return to a normal state of consciousness (p<0.001). Post-stroke epileptic seizures are frequent in our region. Secondary prevention of stroke would help reduce the occurrence of strokes and therefore epileptic seizures}, year = {2020} }
TY - JOUR T1 - Post-Stroke Epileptic Crises: Profile of Patients at Brazzaville Chu AU - Sounga Bandzouzi Prince Eliot Galieni AU - Mpandzou Ghislain Armel AU - Ebelebe Evence Vital AU - Sounga Dufeil AU - Mialoudama Karl AU - Motoula Latou Dina Happhia AU - Diatewa Josue AU - Matali Edgard AU - Obondzo Aloba Karen AU - Koubemba Godefroy Charles AU - Ossou-Nguiet Paul Macaire Y1 - 2020/09/23 PY - 2020 N1 - https://doi.org/10.11648/j.cnn.20200403.15 DO - 10.11648/j.cnn.20200403.15 T2 - Clinical Neurology and Neuroscience JF - Clinical Neurology and Neuroscience JO - Clinical Neurology and Neuroscience SP - 66 EP - 70 PB - Science Publishing Group SN - 2578-8930 UR - https://doi.org/10.11648/j.cnn.20200403.15 AB - Epilepsy and cerebrovascular accident (stroke) are two common conditions in neurology, the frequency of which increases with age. One of the most common comorbidities after a stroke is epilepsy; nearly 10% of stroke patients will have a seizure immediately or later. The aim of study was to describe the epidemiological, clinical, electrical and evolutionary aspects of post-stroke crises at the Brazzaville University Hospital. This was a cross-sectional study carried out from March 1 to September 30, 2018 in the neurology department of the University Hospital of Brazzaville. It focused on patients over 18 years of age hospitalized for a seizure following a stroke documented by imaging. The epidemiological, electroclinical and therapeutic variables were evaluated. 322 patients hospitalized for stroke, 62 (15.5%) presented with seizures following the vascular event. Men were more affected (57%). The median time to onset of seizures was 2478 days (6.8 years) after stroke. These attacks were early in 69.4% of cases, and most often focal (37.1%). The epileptic seizures were related to the arterial infarctions in 79% of the cases and the abnormalities found on the EEG tracing were consistent with the location of the vascular lesion in 63.6% of the cases. The death rate was 14.5%. The predictive factors of this mortality were: the late onset of epileptic seizures (p=0.048), the presence of hyperglycemia (p=0.006) and the absence of a return to a normal state of consciousness (p<0.001). Post-stroke epileptic seizures are frequent in our region. Secondary prevention of stroke would help reduce the occurrence of strokes and therefore epileptic seizures VL - 4 IS - 3 ER -