Rabies was firstly recorded in Oman in August 1990, when a school boy had been bitten by a fox. Within a year, then the virus was recorded among red foxes (Vulpes vulpes). Unlike other developing countries, dog is not the usual agent of rabies transmission in Oman but fox considered the main reservoir (sylvatic transmission). The present study was Carried out to determine the molecular epidemiology of fox rabies virus in Oman. The nucleoprotein (N) genes were amplified from brain of three rabid foxes obtained during (2009-2012). The nucleotide sequences of the genes were subjected to molecular and phylogenic analysis. The phylogenic analysis was performed in relation to Omani foxes isolates and other sequences from the Saudi Arabia (isolated in 1987) available in the GenBank. Results indicated that only one genetic group of fox rabies virus appeared to be circulating in Oman since 1990. The study also showed that the recent isolate (2012) of Omani rabies virus from foxes is closely related (97%) to those viruses isolated from foxes in Saudi Arabia. According to the obtained results, It is clear that since its first diagnosis in 1990 the rabies fox virus has not gone through significant virus variant in Oman, It seems that rabies is maintained endemically in Oman through wild foxes. In conclusion the findings reported here highlight the remarkable genetic stability of rabies virus.
| Published in | Animal and Veterinary Sciences (Volume 6, Issue 1) |
| DOI | 10.11648/j.avs.20180601.14 |
| Page(s) | 17-20 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2018. Published by Science Publishing Group |
Rabies Virus, Fox, Genetic, Gen Bank, Oman
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APA Style
Mohammad Hassan Body, Mohamed Sayed Ahmed, Hatim Hassan Eltahir, Mahir Ghareeb ALmaewaly, Saif Alhabsi. (2018). Molecular Characterization of Rabies Virus from Foxes in the Sultanate of Oman. Animal and Veterinary Sciences, 6(1), 17-20. https://doi.org/10.11648/j.avs.20180601.14
ACS Style
Mohammad Hassan Body; Mohamed Sayed Ahmed; Hatim Hassan Eltahir; Mahir Ghareeb ALmaewaly; Saif Alhabsi. Molecular Characterization of Rabies Virus from Foxes in the Sultanate of Oman. Anim. Vet. Sci. 2018, 6(1), 17-20. doi: 10.11648/j.avs.20180601.14
AMA Style
Mohammad Hassan Body, Mohamed Sayed Ahmed, Hatim Hassan Eltahir, Mahir Ghareeb ALmaewaly, Saif Alhabsi. Molecular Characterization of Rabies Virus from Foxes in the Sultanate of Oman. Anim Vet Sci. 2018;6(1):17-20. doi: 10.11648/j.avs.20180601.14
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Download@article{10.11648/j.avs.20180601.14,
author = {Mohammad Hassan Body and Mohamed Sayed Ahmed and Hatim Hassan Eltahir and Mahir Ghareeb ALmaewaly and Saif Alhabsi},
title = {Molecular Characterization of Rabies Virus from Foxes in the Sultanate of Oman},
journal = {Animal and Veterinary Sciences},
volume = {6},
number = {1},
pages = {17-20},
doi = {10.11648/j.avs.20180601.14},
url = {https://doi.org/10.11648/j.avs.20180601.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20180601.14},
abstract = {Rabies was firstly recorded in Oman in August 1990, when a school boy had been bitten by a fox. Within a year, then the virus was recorded among red foxes (Vulpes vulpes). Unlike other developing countries, dog is not the usual agent of rabies transmission in Oman but fox considered the main reservoir (sylvatic transmission). The present study was Carried out to determine the molecular epidemiology of fox rabies virus in Oman. The nucleoprotein (N) genes were amplified from brain of three rabid foxes obtained during (2009-2012). The nucleotide sequences of the genes were subjected to molecular and phylogenic analysis. The phylogenic analysis was performed in relation to Omani foxes isolates and other sequences from the Saudi Arabia (isolated in 1987) available in the GenBank. Results indicated that only one genetic group of fox rabies virus appeared to be circulating in Oman since 1990. The study also showed that the recent isolate (2012) of Omani rabies virus from foxes is closely related (97%) to those viruses isolated from foxes in Saudi Arabia. According to the obtained results, It is clear that since its first diagnosis in 1990 the rabies fox virus has not gone through significant virus variant in Oman, It seems that rabies is maintained endemically in Oman through wild foxes. In conclusion the findings reported here highlight the remarkable genetic stability of rabies virus.},
year = {2018}
}
TY - JOUR T1 - Molecular Characterization of Rabies Virus from Foxes in the Sultanate of Oman AU - Mohammad Hassan Body AU - Mohamed Sayed Ahmed AU - Hatim Hassan Eltahir AU - Mahir Ghareeb ALmaewaly AU - Saif Alhabsi Y1 - 2018/05/08 PY - 2018 N1 - https://doi.org/10.11648/j.avs.20180601.14 DO - 10.11648/j.avs.20180601.14 T2 - Animal and Veterinary Sciences JF - Animal and Veterinary Sciences JO - Animal and Veterinary Sciences SP - 17 EP - 20 PB - Science Publishing Group SN - 2328-5850 UR - https://doi.org/10.11648/j.avs.20180601.14 AB - Rabies was firstly recorded in Oman in August 1990, when a school boy had been bitten by a fox. Within a year, then the virus was recorded among red foxes (Vulpes vulpes). Unlike other developing countries, dog is not the usual agent of rabies transmission in Oman but fox considered the main reservoir (sylvatic transmission). The present study was Carried out to determine the molecular epidemiology of fox rabies virus in Oman. The nucleoprotein (N) genes were amplified from brain of three rabid foxes obtained during (2009-2012). The nucleotide sequences of the genes were subjected to molecular and phylogenic analysis. The phylogenic analysis was performed in relation to Omani foxes isolates and other sequences from the Saudi Arabia (isolated in 1987) available in the GenBank. Results indicated that only one genetic group of fox rabies virus appeared to be circulating in Oman since 1990. The study also showed that the recent isolate (2012) of Omani rabies virus from foxes is closely related (97%) to those viruses isolated from foxes in Saudi Arabia. According to the obtained results, It is clear that since its first diagnosis in 1990 the rabies fox virus has not gone through significant virus variant in Oman, It seems that rabies is maintained endemically in Oman through wild foxes. In conclusion the findings reported here highlight the remarkable genetic stability of rabies virus. VL - 6 IS - 1 ER -
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