Measurement of Biomarkers Troponin I, NT Pro BNP and ANP Between Horses with Signs of Respiratory Disease and Apparently Healthy Group

Fereydon Rezazadeh; Neda Hosseinzadeh; Nahid Ghaderian

doi:doi:10.11648/j.avs.20160406.11

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Measurement of Biomarkers Troponin I, NT Pro BNP and ANP Between Horses with Signs of Respiratory Disease and Apparently Healthy Group

Fereydon Rezazadeh, Neda Hosseinzadeh, Nahid Ghaderian

Published in Animal and Veterinary Sciences (Volume 4, Issue 6)

Received: 1 October 2016 Accepted: 11 October 2016 Published: 3 November 2016

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Abstract

Biomarkers are biological gnomons of processes or events occurring within the body. Biomarkers can be sub-divided into leakage enzymes (Cardiac troponin I) and functional markers (Natriuretic peptides). Some studies were represented that these biomarkers may be changes in respiratory disorders. Therefore, present study is performed to evaluate serumic levels of cardiac biomarkers between horses with respiratory disease and apparently healthy horses. Initially 10 horses with manifestations of respiratory disease (include increasing of respiratory and heart rate, coughing, mucopurulent and purulent nasal discharge, mucosal hyperemia, increased CRT) and 8 apparently healthy horses underwent a clinical examination. Age, gender, breed and color of individual horses were recorded. CTnI and NT pro BNP were measured by chemiluminescence immunoassay but ANP was measured by ELISA kit in the serum of blood. Electrocardiogram (ECG) has been recorded in base-apex lead in the stall. The mean ages were of 2.1±00.8 and 1.7±0.8 in apparently healthy horses and patient groups, respectively. The mean value level of all cardiac biomarkers (cTnI, ANP and NT pro BNP) in patient group (0.008±0.002 ng/ml, 280.48±79.51 ng/L and 20.34±0.68 pg/ml) was higher than apparently healthy group (0.007±0.002 ng/ml, 206.92±23.01 ng/L and 20.00±0.00 pg/ml). But, the statistical differences between the groups were not significant (P>0.05). No significant differences were found in waveforms of electrocardiograms between two groups.

Published in	Animal and Veterinary Sciences (Volume 4, Issue 6)
DOI	10.11648/j.avs.20160406.11
Page(s)	86-92
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Horse, Biomarker, cTnI, NT pro BNP, ANP

References

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APA Style

Fereydon Rezazadeh, Neda Hosseinzadeh, Nahid Ghaderian. (2016). Measurement of Biomarkers Troponin I, NT Pro BNP and ANP Between Horses with Signs of Respiratory Disease and Apparently Healthy Group. Animal and Veterinary Sciences, 4(6), 86-92. https://doi.org/10.11648/j.avs.20160406.11

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ACS Style

Fereydon Rezazadeh; Neda Hosseinzadeh; Nahid Ghaderian. Measurement of Biomarkers Troponin I, NT Pro BNP and ANP Between Horses with Signs of Respiratory Disease and Apparently Healthy Group. Anim. Vet. Sci. 2016, 4(6), 86-92. doi: 10.11648/j.avs.20160406.11

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AMA Style

Fereydon Rezazadeh, Neda Hosseinzadeh, Nahid Ghaderian. Measurement of Biomarkers Troponin I, NT Pro BNP and ANP Between Horses with Signs of Respiratory Disease and Apparently Healthy Group. Anim Vet Sci. 2016;4(6):86-92. doi: 10.11648/j.avs.20160406.11

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@article{10.11648/j.avs.20160406.11,
  author = {Fereydon Rezazadeh and Neda Hosseinzadeh and Nahid Ghaderian},
  title = {Measurement of Biomarkers Troponin I, NT Pro BNP and ANP Between Horses with Signs of Respiratory Disease and Apparently Healthy Group},
  journal = {Animal and Veterinary Sciences},
  volume = {4},
  number = {6},
  pages = {86-92},
  doi = {10.11648/j.avs.20160406.11},
  url = {https://doi.org/10.11648/j.avs.20160406.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20160406.11},
  abstract = {Biomarkers are biological gnomons of processes or events occurring within the body. Biomarkers can be sub-divided into leakage enzymes (Cardiac troponin I) and functional markers (Natriuretic peptides). Some studies were represented that these biomarkers may be changes in respiratory disorders. Therefore, present study is performed to evaluate serumic levels of cardiac biomarkers between horses with respiratory disease and apparently healthy horses. Initially 10 horses with manifestations of respiratory disease (include increasing of respiratory and heart rate, coughing, mucopurulent and purulent nasal discharge, mucosal hyperemia, increased CRT) and 8 apparently healthy horses underwent a clinical examination. Age, gender, breed and color of individual horses were recorded. CTnI and NT pro BNP were measured by chemiluminescence immunoassay but ANP was measured by ELISA kit in the serum of blood. Electrocardiogram (ECG) has been recorded in base-apex lead in the stall. The mean ages were of 2.1±00.8 and 1.7±0.8 in apparently healthy horses and patient groups, respectively. The mean value level of all cardiac biomarkers (cTnI, ANP and NT pro BNP) in patient group (0.008±0.002 ng/ml, 280.48±79.51 ng/L and 20.34±0.68 pg/ml) was higher than apparently healthy group (0.007±0.002 ng/ml, 206.92±23.01 ng/L and 20.00±0.00 pg/ml). But, the statistical differences between the groups were not significant (P>0.05). No significant differences were found in waveforms of electrocardiograms between two groups.},
 year = {2016}
}

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TY - JOUR
T1 - Measurement of Biomarkers Troponin I, NT Pro BNP and ANP Between Horses with Signs of Respiratory Disease and Apparently Healthy Group
AU - Fereydon Rezazadeh
AU - Neda Hosseinzadeh
AU - Nahid Ghaderian
Y1 - 2016/11/03
PY - 2016
N1 - https://doi.org/10.11648/j.avs.20160406.11
DO - 10.11648/j.avs.20160406.11
T2 - Animal and Veterinary Sciences
JF - Animal and Veterinary Sciences
JO - Animal and Veterinary Sciences
SP - 86
EP - 92
PB - Science Publishing Group
SN - 2328-5850
UR - https://doi.org/10.11648/j.avs.20160406.11
AB - Biomarkers are biological gnomons of processes or events occurring within the body. Biomarkers can be sub-divided into leakage enzymes (Cardiac troponin I) and functional markers (Natriuretic peptides). Some studies were represented that these biomarkers may be changes in respiratory disorders. Therefore, present study is performed to evaluate serumic levels of cardiac biomarkers between horses with respiratory disease and apparently healthy horses. Initially 10 horses with manifestations of respiratory disease (include increasing of respiratory and heart rate, coughing, mucopurulent and purulent nasal discharge, mucosal hyperemia, increased CRT) and 8 apparently healthy horses underwent a clinical examination. Age, gender, breed and color of individual horses were recorded. CTnI and NT pro BNP were measured by chemiluminescence immunoassay but ANP was measured by ELISA kit in the serum of blood. Electrocardiogram (ECG) has been recorded in base-apex lead in the stall. The mean ages were of 2.1±00.8 and 1.7±0.8 in apparently healthy horses and patient groups, respectively. The mean value level of all cardiac biomarkers (cTnI, ANP and NT pro BNP) in patient group (0.008±0.002 ng/ml, 280.48±79.51 ng/L and 20.34±0.68 pg/ml) was higher than apparently healthy group (0.007±0.002 ng/ml, 206.92±23.01 ng/L and 20.00±0.00 pg/ml). But, the statistical differences between the groups were not significant (P>0.05). No significant differences were found in waveforms of electrocardiograms between two groups.
VL - 4
IS - 6
ER -

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Author Information

Fereydon Rezazadeh

Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
Neda Hosseinzadeh

Veterinary Pharmacology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Nahid Ghaderian

Specialist in Clinical-anatomical Pathology, Nour Medical Laboratory, Tabriz, Iran

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Fereydon Rezazadeh, Neda Hosseinzadeh, Nahid Ghaderian. (2016). Measurement of Biomarkers Troponin I, NT Pro BNP and ANP Between Horses with Signs of Respiratory Disease and Apparently Healthy Group. Animal and Veterinary Sciences, 4(6), 86-92. https://doi.org/10.11648/j.avs.20160406.11

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ACS Style

Fereydon Rezazadeh; Neda Hosseinzadeh; Nahid Ghaderian. Measurement of Biomarkers Troponin I, NT Pro BNP and ANP Between Horses with Signs of Respiratory Disease and Apparently Healthy Group. Anim. Vet. Sci. 2016, 4(6), 86-92. doi: 10.11648/j.avs.20160406.11

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AMA Style

Fereydon Rezazadeh, Neda Hosseinzadeh, Nahid Ghaderian. Measurement of Biomarkers Troponin I, NT Pro BNP and ANP Between Horses with Signs of Respiratory Disease and Apparently Healthy Group. Anim Vet Sci. 2016;4(6):86-92. doi: 10.11648/j.avs.20160406.11

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@article{10.11648/j.avs.20160406.11,
  author = {Fereydon Rezazadeh and Neda Hosseinzadeh and Nahid Ghaderian},
  title = {Measurement of Biomarkers Troponin I, NT Pro BNP and ANP Between Horses with Signs of Respiratory Disease and Apparently Healthy Group},
  journal = {Animal and Veterinary Sciences},
  volume = {4},
  number = {6},
  pages = {86-92},
  doi = {10.11648/j.avs.20160406.11},
  url = {https://doi.org/10.11648/j.avs.20160406.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20160406.11},
  abstract = {Biomarkers are biological gnomons of processes or events occurring within the body. Biomarkers can be sub-divided into leakage enzymes (Cardiac troponin I) and functional markers (Natriuretic peptides). Some studies were represented that these biomarkers may be changes in respiratory disorders. Therefore, present study is performed to evaluate serumic levels of cardiac biomarkers between horses with respiratory disease and apparently healthy horses. Initially 10 horses with manifestations of respiratory disease (include increasing of respiratory and heart rate, coughing, mucopurulent and purulent nasal discharge, mucosal hyperemia, increased CRT) and 8 apparently healthy horses underwent a clinical examination. Age, gender, breed and color of individual horses were recorded. CTnI and NT pro BNP were measured by chemiluminescence immunoassay but ANP was measured by ELISA kit in the serum of blood. Electrocardiogram (ECG) has been recorded in base-apex lead in the stall. The mean ages were of 2.1±00.8 and 1.7±0.8 in apparently healthy horses and patient groups, respectively. The mean value level of all cardiac biomarkers (cTnI, ANP and NT pro BNP) in patient group (0.008±0.002 ng/ml, 280.48±79.51 ng/L and 20.34±0.68 pg/ml) was higher than apparently healthy group (0.007±0.002 ng/ml, 206.92±23.01 ng/L and 20.00±0.00 pg/ml). But, the statistical differences between the groups were not significant (P>0.05). No significant differences were found in waveforms of electrocardiograms between two groups.},
 year = {2016}
}

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