Response of Pullet Chicks to Dietary Fumonisin B1: Growth Indices and Haematological Parameters

Ogunlade Jacob Taiwo

doi:doi:10.11648/j.avs.20150302.11

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Response of Pullet Chicks to Dietary Fumonisin B1: Growth Indices and Haematological Parameters

Ogunlade Jacob Taiwo

Published in Animal and Veterinary Sciences (Volume 3, Issue 2)

Received: 23 January 2015 Accepted: 6 February 2015 Published: 13 February 2015

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Abstract

Growth indices and heamatological parameters of 180 Isa brownpullet chicks fed graded levels of dietary fumonisin B1 (an environmental mycotoxin produced by Fusariumverticillioides) were studied in a feeding trial that lasted nine weeks. The chicks, having similar initial average weights were randomly assigned to four experimental diets containing 0.2, 5.2, 10.2, and 15.2 mgFB1/kg constituting diets 1( control), 2, 3, and 4 respectivelyin a completely randomized design. Each dietary treatment had three replicates of 15 chicks each. The feed intake was monitored daily and the chicks weighed weekly. Blood samples were collected at the end of the trial and analyzed. Results revealed a non-significant (P>0.05) but FB1 concentration dependent decrease in daily feed intake, final live weight and daily weight gain of chicks fed diets 2, 3, and 4 when compared with those on diet 1. Crude protein and ether extract digestibility decreased significantly (P < 0.05) as the dietary FB1 levels increased. The dry matter digestibility of chicks on diets 2, 3, and 4 were 94.77, 95.07 and 94.81 % respectively of the control value. Chicks fed diets containing 10.2 and 15.2 mg FB1/kg suffered significantly (P < 0.05) reduced concentration of erythrocytesand mean corpuscular heamoglobin concentration (MCHC). Lymphocytes significantly decline (lymphopenia) while heterophils significantly increased with increase in dietary FB1 suggesting a condition of immunosuppression and tissue degeneration respectively in chicks fed diets 3 and 4. The study demonstrated that pullets chicks exposed to dietary fumonisin concentration of 10.20mg/kg diet and above would suffer depressed apparent crude protein and ether extract digestibility and decreased synthesis of erythrocyte, MCHC and lymphocytes.

Published in	Animal and Veterinary Sciences (Volume 3, Issue 2)
DOI	10.11648/j.avs.20150302.11
Page(s)	37-40
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Mycotoxin, Poultry, Digestibility, Blood Profile

References

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[2]	Coles, E.H.(1986). Veterinary clinical pathology.4th ed. W.B. Saunders company, Philadelphia, London and Toronto. Pp 99-148
[3]	Ewuola, E.O., Ogunlade, J.T., Gbore, F.A., Salako, A. O., Idahor, K.O. and Egbunike, G.N. (2003). Performance evaluation and organ histology of rabbits fed Fusariumverticillioides culture material. Trop. Anim. Prod. 6 (2): 111-119
[4]	Fazekas, B., Bajmocy, E., Glavics, R. and Fenyvesi, A. (1997). Fumonisinmycoticoses in Hungary. Leuco-encephalomalacia in horses, fattening pulmonary oedema in pigs. Magy. Allartov. Lapja., 119 : 137-139
[5]	Gbore, F.A, Ogunlade, J.T, Ewuola, E. O. and Egbunike G.N. (2010). Growth indices and haematological parameters of weanling pigs fed dietary fumonisin B1.Nig. J. Anim. Prod. 37 (1) : 123-134.
[6]	Gelderblom, W. C. A., Cawood, M. E., Snyman, S. D., and Marasas, W. F. O. (1994). Fumonisin B1dosimetry in relation to cancer initiation in rat liver. Carcinogenesis, 15 : 209-214
[7]	Ledoux, D.R., Brown, T. P., Weibking, T.S. and Rottinghaus, G. E. (1992). Fumonisin toxicity in broiler chicks. J. Vet. Diagn. Invest. 4: 330-333
[8]	Marijanovic, D.R., Holt, P.,Norred, W.P., Bacon, C.W., Voss, K.A., Stancel, P.C. and Ragland, W.L.(1991). Immunosuppressive effects of F. moniliforme corn culture in chickens. Poult. Sci., 70: 1895-1901
[9]	Mitruka, B. M and Rawnsley, H. M. (1977). Clinical biochemical and haematological reference values in normal experimental animals. Masson Pub. USA Inc., N. Y. pp. 21-84
[10]	Nelson, P. E., Juba, J. H., Ross, P. F. and Rice, L. G. (1994). Fumonisin production by Fusarium species on solid substrates. J. Assoc. Off. Anal. Chem. Int., 77: 522-524.
[11]	Ogunlade, J. T., Gbore, F. A., Ewuola, E. O., Idahor, K. O., Salako, A. O. and Egbunike, G. N. (2004). Biochemical and Haematological Responses of Rabbits Fed Diets containing micro doses ofFumonisin .Trop. J. Anim. Sci. 7 (1) : 169-176
[12]	Ogunlade, J. T. and Egbunike, G. N. (2013). FumonisinMycotoxicity in laying hens: Haematology, serum biochemistry and organ characteristics. Glob. Adv. Res. Jour. Of Env. Sc. and Toxicol. 2(2) : 47 – 53
[13]	Oluyemi, J.A. and Roberts, F.A. (2000). Poultry production in warm wet climates. 2nd ed. Spectrum Book Ltd. (Publ.), Ibadan, Nigeria. pp. 1-7.
[14]	Parent-Massin, D. and Parchment, R.E.(1998). Haematotoxicity of mycotoxins. In: Le Bass, J., Galties, P. (eds.). Mycotoxins in the food chain, MYCOTOX ’98, Toulouse, July 2-4, pp. 591-598.
[15]	US FDA (2000). Background paper in support of fumonisin levels in animal feed. US Food and Drug Administration Center for Veterinary Medicine, June 6, 2000.
[16]	US NTP (1999). NTP technical report on the toxicology and carcinogenesis studies of fumonisin B1(CAS No. 116355-83-0) in F344/N rats and B6C3F1 mice (feed studies). Research Triangle Park, North Carolina, US Department of Health and Human Services National Toxicology Program (NTP TR 496; NIH Publication No.
[17]	Voss, K.A., Chamberlain, W.J., Bacon, C.W. and Norred, W.P. (1993). A preliminary investigation on renal and hepatic toxicity in rats fed purifiedfumonisin B1. Nat. Toxins., 1: 222-228.
[18]	Yoo, H. S., Norred, W. P., Wang, E., Merill, A. H. Jr., and Riley, R. T. (1992). Fumonisin inhibition of de novo sphingolipid biosynthesis and cytotoxicity are correlated in LLC-PK1 cells. Toxicol. Appl. Pharmacol., 114 : 9-15
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Ogunlade Jacob Taiwo. (2015). Response of Pullet Chicks to Dietary Fumonisin B1: Growth Indices and Haematological Parameters. Animal and Veterinary Sciences, 3(2), 37-40. https://doi.org/10.11648/j.avs.20150302.11

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Ogunlade Jacob Taiwo. Response of Pullet Chicks to Dietary Fumonisin B1: Growth Indices and Haematological Parameters. Anim. Vet. Sci. 2015, 3(2), 37-40. doi: 10.11648/j.avs.20150302.11

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AMA Style

Ogunlade Jacob Taiwo. Response of Pullet Chicks to Dietary Fumonisin B1: Growth Indices and Haematological Parameters. Anim Vet Sci. 2015;3(2):37-40. doi: 10.11648/j.avs.20150302.11

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@article{10.11648/j.avs.20150302.11,
  author = {Ogunlade Jacob Taiwo},
  title = {Response of Pullet Chicks to Dietary Fumonisin B1: Growth Indices and Haematological Parameters},
  journal = {Animal and Veterinary Sciences},
  volume = {3},
  number = {2},
  pages = {37-40},
  doi = {10.11648/j.avs.20150302.11},
  url = {https://doi.org/10.11648/j.avs.20150302.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20150302.11},
  abstract = {Growth indices and heamatological parameters of 180 Isa brownpullet chicks fed graded levels of dietary fumonisin B1 (an environmental mycotoxin produced by Fusariumverticillioides) were studied in a feeding trial that lasted nine weeks. The chicks, having similar initial average weights were randomly assigned to four experimental diets containing 0.2, 5.2, 10.2, and 15.2 mgFB1/kg constituting diets 1( control), 2, 3, and 4 respectivelyin a completely randomized design. Each dietary treatment had three replicates of 15 chicks each. The feed intake was monitored daily and the chicks weighed weekly. Blood samples were collected at the end of the trial and analyzed. Results revealed a non-significant (P>0.05) but FB1 concentration dependent decrease in daily feed intake, final live weight and daily weight gain of chicks fed diets 2, 3, and 4 when compared with those on diet 1. Crude protein and ether extract digestibility decreased significantly (P < 0.05) as the dietary FB1 levels increased. The dry matter digestibility of chicks on diets 2, 3, and 4 were 94.77, 95.07 and 94.81 % respectively of the control value. Chicks fed diets containing 10.2 and 15.2 mg FB1/kg suffered significantly (P < 0.05) reduced concentration of erythrocytesand mean corpuscular heamoglobin concentration (MCHC). Lymphocytes significantly decline (lymphopenia) while heterophils significantly increased with increase in dietary FB1 suggesting a condition of immunosuppression and tissue degeneration respectively in chicks fed diets 3 and 4. The study demonstrated that pullets chicks exposed to dietary fumonisin concentration of 10.20mg/kg diet and above would suffer depressed apparent crude protein and ether extract digestibility and decreased synthesis of erythrocyte, MCHC and lymphocytes.},
 year = {2015}
}

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TY  - JOUR
T1  - Response of Pullet Chicks to Dietary Fumonisin B1: Growth Indices and Haematological Parameters
AU  - Ogunlade Jacob Taiwo
Y1  - 2015/02/13
PY  - 2015
N1  - https://doi.org/10.11648/j.avs.20150302.11
DO  - 10.11648/j.avs.20150302.11
T2  - Animal and Veterinary Sciences
JF  - Animal and Veterinary Sciences
JO  - Animal and Veterinary Sciences
SP  - 37
EP  - 40
PB  - Science Publishing Group
SN  - 2328-5850
UR  - https://doi.org/10.11648/j.avs.20150302.11
AB  - Growth indices and heamatological parameters of 180 Isa brownpullet chicks fed graded levels of dietary fumonisin B1 (an environmental mycotoxin produced by Fusariumverticillioides) were studied in a feeding trial that lasted nine weeks. The chicks, having similar initial average weights were randomly assigned to four experimental diets containing 0.2, 5.2, 10.2, and 15.2 mgFB1/kg constituting diets 1( control), 2, 3, and 4 respectivelyin a completely randomized design. Each dietary treatment had three replicates of 15 chicks each. The feed intake was monitored daily and the chicks weighed weekly. Blood samples were collected at the end of the trial and analyzed. Results revealed a non-significant (P>0.05) but FB1 concentration dependent decrease in daily feed intake, final live weight and daily weight gain of chicks fed diets 2, 3, and 4 when compared with those on diet 1. Crude protein and ether extract digestibility decreased significantly (P < 0.05) as the dietary FB1 levels increased. The dry matter digestibility of chicks on diets 2, 3, and 4 were 94.77, 95.07 and 94.81 % respectively of the control value. Chicks fed diets containing 10.2 and 15.2 mg FB1/kg suffered significantly (P < 0.05) reduced concentration of erythrocytesand mean corpuscular heamoglobin concentration (MCHC). Lymphocytes significantly decline (lymphopenia) while heterophils significantly increased with increase in dietary FB1 suggesting a condition of immunosuppression and tissue degeneration respectively in chicks fed diets 3 and 4. The study demonstrated that pullets chicks exposed to dietary fumonisin concentration of 10.20mg/kg diet and above would suffer depressed apparent crude protein and ether extract digestibility and decreased synthesis of erythrocyte, MCHC and lymphocytes.
VL  - 3
IS  - 2
ER  -

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Author Information

Ogunlade Jacob Taiwo

Department of Animal Production and Health Sciences, Faculty of Agricultural Sciences, Ekiti State University, Ado-Ekiti, Nigeria

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Ogunlade Jacob Taiwo. (2015). Response of Pullet Chicks to Dietary Fumonisin B1: Growth Indices and Haematological Parameters. Animal and Veterinary Sciences, 3(2), 37-40. https://doi.org/10.11648/j.avs.20150302.11

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ACS Style

Ogunlade Jacob Taiwo. Response of Pullet Chicks to Dietary Fumonisin B1: Growth Indices and Haematological Parameters. Anim. Vet. Sci. 2015, 3(2), 37-40. doi: 10.11648/j.avs.20150302.11

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AMA Style

Ogunlade Jacob Taiwo. Response of Pullet Chicks to Dietary Fumonisin B1: Growth Indices and Haematological Parameters. Anim Vet Sci. 2015;3(2):37-40. doi: 10.11648/j.avs.20150302.11

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@article{10.11648/j.avs.20150302.11,
  author = {Ogunlade Jacob Taiwo},
  title = {Response of Pullet Chicks to Dietary Fumonisin B1: Growth Indices and Haematological Parameters},
  journal = {Animal and Veterinary Sciences},
  volume = {3},
  number = {2},
  pages = {37-40},
  doi = {10.11648/j.avs.20150302.11},
  url = {https://doi.org/10.11648/j.avs.20150302.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20150302.11},
  abstract = {Growth indices and heamatological parameters of 180 Isa brownpullet chicks fed graded levels of dietary fumonisin B1 (an environmental mycotoxin produced by Fusariumverticillioides) were studied in a feeding trial that lasted nine weeks. The chicks, having similar initial average weights were randomly assigned to four experimental diets containing 0.2, 5.2, 10.2, and 15.2 mgFB1/kg constituting diets 1( control), 2, 3, and 4 respectivelyin a completely randomized design. Each dietary treatment had three replicates of 15 chicks each. The feed intake was monitored daily and the chicks weighed weekly. Blood samples were collected at the end of the trial and analyzed. Results revealed a non-significant (P>0.05) but FB1 concentration dependent decrease in daily feed intake, final live weight and daily weight gain of chicks fed diets 2, 3, and 4 when compared with those on diet 1. Crude protein and ether extract digestibility decreased significantly (P < 0.05) as the dietary FB1 levels increased. The dry matter digestibility of chicks on diets 2, 3, and 4 were 94.77, 95.07 and 94.81 % respectively of the control value. Chicks fed diets containing 10.2 and 15.2 mg FB1/kg suffered significantly (P < 0.05) reduced concentration of erythrocytesand mean corpuscular heamoglobin concentration (MCHC). Lymphocytes significantly decline (lymphopenia) while heterophils significantly increased with increase in dietary FB1 suggesting a condition of immunosuppression and tissue degeneration respectively in chicks fed diets 3 and 4. The study demonstrated that pullets chicks exposed to dietary fumonisin concentration of 10.20mg/kg diet and above would suffer depressed apparent crude protein and ether extract digestibility and decreased synthesis of erythrocyte, MCHC and lymphocytes.},
 year = {2015}
}

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TY  - JOUR
T1  - Response of Pullet Chicks to Dietary Fumonisin B1: Growth Indices and Haematological Parameters
AU  - Ogunlade Jacob Taiwo
Y1  - 2015/02/13
PY  - 2015
N1  - https://doi.org/10.11648/j.avs.20150302.11
DO  - 10.11648/j.avs.20150302.11
T2  - Animal and Veterinary Sciences
JF  - Animal and Veterinary Sciences
JO  - Animal and Veterinary Sciences
SP  - 37
EP  - 40
PB  - Science Publishing Group
SN  - 2328-5850
UR  - https://doi.org/10.11648/j.avs.20150302.11
AB  - Growth indices and heamatological parameters of 180 Isa brownpullet chicks fed graded levels of dietary fumonisin B1 (an environmental mycotoxin produced by Fusariumverticillioides) were studied in a feeding trial that lasted nine weeks. The chicks, having similar initial average weights were randomly assigned to four experimental diets containing 0.2, 5.2, 10.2, and 15.2 mgFB1/kg constituting diets 1( control), 2, 3, and 4 respectivelyin a completely randomized design. Each dietary treatment had three replicates of 15 chicks each. The feed intake was monitored daily and the chicks weighed weekly. Blood samples were collected at the end of the trial and analyzed. Results revealed a non-significant (P>0.05) but FB1 concentration dependent decrease in daily feed intake, final live weight and daily weight gain of chicks fed diets 2, 3, and 4 when compared with those on diet 1. Crude protein and ether extract digestibility decreased significantly (P < 0.05) as the dietary FB1 levels increased. The dry matter digestibility of chicks on diets 2, 3, and 4 were 94.77, 95.07 and 94.81 % respectively of the control value. Chicks fed diets containing 10.2 and 15.2 mg FB1/kg suffered significantly (P < 0.05) reduced concentration of erythrocytesand mean corpuscular heamoglobin concentration (MCHC). Lymphocytes significantly decline (lymphopenia) while heterophils significantly increased with increase in dietary FB1 suggesting a condition of immunosuppression and tissue degeneration respectively in chicks fed diets 3 and 4. The study demonstrated that pullets chicks exposed to dietary fumonisin concentration of 10.20mg/kg diet and above would suffer depressed apparent crude protein and ether extract digestibility and decreased synthesis of erythrocyte, MCHC and lymphocytes.
VL  - 3
IS  - 2
ER  -

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