Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor

Guo Rongzeng; Yang Zhongxu; Cui Lihua; You Zehong; Du Ligong; Wang Yan; Tang Zhensheng

doi:doi:10.11648/j.ass.20190701.13

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Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor

Guo Rongzeng, Yang Zhongxu, Cui Lihua, You Zehong, Du Ligong, Wang Yan, Tang Zhensheng

Published in Advances in Surgical Sciences (Volume 7, Issue 1)

Received: 16 December 2018 Accepted: 3 January 2019 Published: 15 February 2019

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Abstract

Objective Investigating the surgical treatment for dysembryoplastic neuroepithelial tumor. Methods A total of 12 cases (7 males, 5 females, aged 4~36 years) of dysembryoplastic neuroepithelial tumors from 2010 to 2014 in Shanghai Blue Cross Brain Hospital were analyzed retrospectively, including 9 cases of temporal lobe tumor, 2 cases of frontal lobe tumor, and 1 case of parietal lobe tumor. The tumors and epileptogenic foci outside the lesions were resected under the guidance of electrocorticogram in all patients. Results The pathological examination showed that all the tumors were dysembryoplastic neuroepithelial tumors. All the patients had been followed up for 2 to 4 years. Epilepsy occurred in 2 patients and the others were seizure free after the surgery. No tumor recurrence occurred during the follow-up. Conclusion Dysembryoplastic neuroepithelial tumor is a benign tumor often causes intractable epilepsy, which can be controlled by the extended excision of the tumors and epileptogenic cortex under the guidance of electrocorticogram.

Published in	Advances in Surgical Sciences (Volume 7, Issue 1)
DOI	10.11648/j.ass.20190701.13
Page(s)	9-14
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Dysembryoplastic Neuroepithelial Tumors (DNET), Intractable Epilepsy, Electrocorticogram (ECoG), Surgery, Extended Resection

References

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[3]	Yang Shujie, wang Dandan, Wang Ying, et al. MRI manifestations of embryonic dysplasia neuroepithelioma [J]. Journal of medical imaging, 2011, 21 (7) 967-970.
[4]	Isler C, Erturk Cetin O, Ugurlar D, et al. Dysembryoplastic neuroepithelial tumours: clinical, radiological, pathological features and outcome [J]. Br J Neurosurg 2018 Aug; 32 (4): 436-441.
[5]	Chen Li, Xu QingZhong, Pu YueShan et al. Neuroepithelial neoplasm and cortical dysplasia due to embryonic dysplasia [J]. Chinese journal of pathology, 2007, 36 (8):524-528.
[6]	Yu Kai, Yu Shizhu, Zhang Jianning, et al. Clinical and pathological analysis of neuroepithelial neoplasm with embryonic dysplasia [J]. Chinese journal of neurosurgery, 2006, 22 (4):208-211.
[7]	Chen Li, Lu Dehong, Xu Qingzhong. Clinicopathological observation of 11 cases of neuroepithelial neoplasm with embryonic dysplasia [J]. Chin J neurosci, 2006, 39 (8):525-528.
[8]	Moazzam Alan A, Wagle Naveed, Shiroishi, et al. Malignant transformation of DNETs: a case report and literature review [J]. Neuroreport. 2014V25N12:894-9.
[9]	Fallah A, Weil AG, Sur S, et al. Epilepsy surgery related to pediatric brain tumors: Miami Children's Hospital experience [J]. J Neurosurg Pediatr. 2015 Dec, 16 (6):675-80.
[10]	Minkin K, Klein O, Mancini J, et al. Surgical strategies and seizure control in pediatric patients with dysembryoplastic neuroepithelial tumors: a single institution experience [J]. J Neurosurg Pediatrics, 2008, 1 (3):206-210.
[11]	Daumas Dupport C, Scheithauer BW, Chodkiewicz JP, et al. Dsembryoplastic neuroepithelial tumor:a surgically curable tumor of young patients with intractable partial seizures. Report of thirty-nine cases [J]. Neurosurgery, 1988, 23 (7):545-556.
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[14]	Vogt VL, Witt JA, Delev D, et al. Cognitive features and surgical outcome of patients with long-term epilepsy-associated tumors within the temporal lobe [J]. Journal of epilepsy Behav. 2018 Nov, 88:25-32.
[15]	Englot DJ, Berger MS, Barbaro NM, et al. Factors associated with seizure freedom in the surgical resection of glioneuronal tumors [J]. Epilepsia, 2012, 53 (1):51-57.
[16]	Gao Xiang, Wang Yin, Jiang Chengchuan, et al. Diagnosis and treatment of neuroepithelioma with embryonic dysplasia [J]. Chinese journal of neurosurgical diseases, 2004 (02):145-148.

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APA Style

Guo Rongzeng, Yang Zhongxu, Cui Lihua, You Zehong, Du Ligong, et al. (2019). Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor. Advances in Surgical Sciences, 7(1), 9-14. https://doi.org/10.11648/j.ass.20190701.13

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ACS Style

Guo Rongzeng; Yang Zhongxu; Cui Lihua; You Zehong; Du Ligong, et al. Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor. Adv. Surg. Sci. 2019, 7(1), 9-14. doi: 10.11648/j.ass.20190701.13

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AMA Style

Guo Rongzeng, Yang Zhongxu, Cui Lihua, You Zehong, Du Ligong, et al. Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor. Adv Surg Sci. 2019;7(1):9-14. doi: 10.11648/j.ass.20190701.13

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@article{10.11648/j.ass.20190701.13,
  author = {Guo Rongzeng and Yang Zhongxu and Cui Lihua and You Zehong and Du Ligong and Wang Yan and Tang Zhensheng},
  title = {Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor},
  journal = {Advances in Surgical Sciences},
  volume = {7},
  number = {1},
  pages = {9-14},
  doi = {10.11648/j.ass.20190701.13},
  url = {https://doi.org/10.11648/j.ass.20190701.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ass.20190701.13},
  abstract = {Objective Investigating the surgical treatment for dysembryoplastic neuroepithelial tumor. Methods A total of 12 cases (7 males, 5 females, aged 4~36 years) of dysembryoplastic neuroepithelial tumors from 2010 to 2014 in Shanghai Blue Cross Brain Hospital were analyzed retrospectively, including 9 cases of temporal lobe tumor, 2 cases of frontal lobe tumor, and 1 case of parietal lobe tumor. The tumors and epileptogenic foci outside the lesions were resected under the guidance of electrocorticogram in all patients. Results The pathological examination showed that all the tumors were dysembryoplastic neuroepithelial tumors. All the patients had been followed up for 2 to 4 years. Epilepsy occurred in 2 patients and the others were seizure free after the surgery. No tumor recurrence occurred during the follow-up. Conclusion Dysembryoplastic neuroepithelial tumor is a benign tumor often causes intractable epilepsy, which can be controlled by the extended excision of the tumors and epileptogenic cortex under the guidance of electrocorticogram.},
 year = {2019}
}

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TY  - JOUR
T1  - Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor
AU  - Guo Rongzeng
AU  - Yang Zhongxu
AU  - Cui Lihua
AU  - You Zehong
AU  - Du Ligong
AU  - Wang Yan
AU  - Tang Zhensheng
Y1  - 2019/02/15
PY  - 2019
N1  - https://doi.org/10.11648/j.ass.20190701.13
DO  - 10.11648/j.ass.20190701.13
T2  - Advances in Surgical Sciences
JF  - Advances in Surgical Sciences
JO  - Advances in Surgical Sciences
SP  - 9
EP  - 14
PB  - Science Publishing Group
SN  - 2376-6182
UR  - https://doi.org/10.11648/j.ass.20190701.13
AB  - Objective Investigating the surgical treatment for dysembryoplastic neuroepithelial tumor. Methods A total of 12 cases (7 males, 5 females, aged 4~36 years) of dysembryoplastic neuroepithelial tumors from 2010 to 2014 in Shanghai Blue Cross Brain Hospital were analyzed retrospectively, including 9 cases of temporal lobe tumor, 2 cases of frontal lobe tumor, and 1 case of parietal lobe tumor. The tumors and epileptogenic foci outside the lesions were resected under the guidance of electrocorticogram in all patients. Results The pathological examination showed that all the tumors were dysembryoplastic neuroepithelial tumors. All the patients had been followed up for 2 to 4 years. Epilepsy occurred in 2 patients and the others were seizure free after the surgery. No tumor recurrence occurred during the follow-up. Conclusion Dysembryoplastic neuroepithelial tumor is a benign tumor often causes intractable epilepsy, which can be controlled by the extended excision of the tumors and epileptogenic cortex under the guidance of electrocorticogram.
VL  - 7
IS  - 1
ER  -

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Author Information

Guo Rongzeng

Department of Functional Neurosurgery, Shanghai Blue Cross Brain Hospital, Shanghai, China
Yang Zhongxu

Department of Neurosurgery, the First Hospital of Tsinghua University, Beijing, China
Cui Lihua

Department of Functional Neurosurgery, Shanghai Blue Cross Brain Hospital, Shanghai, China
You Zehong

Department of Functional Neurosurgery, Shanghai Blue Cross Brain Hospital, Shanghai, China
Du Ligong

Department of Functional Neurosurgery, Shanghai Blue Cross Brain Hospital, Shanghai, China
Wang Yan

Center of Pathology, Fudan University, Shanghai, China
Tang Zhensheng

Department of Functional Neurosurgery, Shanghai Blue Cross Brain Hospital, Shanghai, China

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Plain Text BibTeX RIS

APA Style

Guo Rongzeng, Yang Zhongxu, Cui Lihua, You Zehong, Du Ligong, et al. (2019). Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor. Advances in Surgical Sciences, 7(1), 9-14. https://doi.org/10.11648/j.ass.20190701.13

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ACS Style

Guo Rongzeng; Yang Zhongxu; Cui Lihua; You Zehong; Du Ligong, et al. Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor. Adv. Surg. Sci. 2019, 7(1), 9-14. doi: 10.11648/j.ass.20190701.13

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AMA Style

Guo Rongzeng, Yang Zhongxu, Cui Lihua, You Zehong, Du Ligong, et al. Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor. Adv Surg Sci. 2019;7(1):9-14. doi: 10.11648/j.ass.20190701.13

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@article{10.11648/j.ass.20190701.13,
  author = {Guo Rongzeng and Yang Zhongxu and Cui Lihua and You Zehong and Du Ligong and Wang Yan and Tang Zhensheng},
  title = {Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor},
  journal = {Advances in Surgical Sciences},
  volume = {7},
  number = {1},
  pages = {9-14},
  doi = {10.11648/j.ass.20190701.13},
  url = {https://doi.org/10.11648/j.ass.20190701.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ass.20190701.13},
  abstract = {Objective Investigating the surgical treatment for dysembryoplastic neuroepithelial tumor. Methods A total of 12 cases (7 males, 5 females, aged 4~36 years) of dysembryoplastic neuroepithelial tumors from 2010 to 2014 in Shanghai Blue Cross Brain Hospital were analyzed retrospectively, including 9 cases of temporal lobe tumor, 2 cases of frontal lobe tumor, and 1 case of parietal lobe tumor. The tumors and epileptogenic foci outside the lesions were resected under the guidance of electrocorticogram in all patients. Results The pathological examination showed that all the tumors were dysembryoplastic neuroepithelial tumors. All the patients had been followed up for 2 to 4 years. Epilepsy occurred in 2 patients and the others were seizure free after the surgery. No tumor recurrence occurred during the follow-up. Conclusion Dysembryoplastic neuroepithelial tumor is a benign tumor often causes intractable epilepsy, which can be controlled by the extended excision of the tumors and epileptogenic cortex under the guidance of electrocorticogram.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - Surgical Treatment of Dysembryoplastic Neuroepithelial Tumor
AU  - Guo Rongzeng
AU  - Yang Zhongxu
AU  - Cui Lihua
AU  - You Zehong
AU  - Du Ligong
AU  - Wang Yan
AU  - Tang Zhensheng
Y1  - 2019/02/15
PY  - 2019
N1  - https://doi.org/10.11648/j.ass.20190701.13
DO  - 10.11648/j.ass.20190701.13
T2  - Advances in Surgical Sciences
JF  - Advances in Surgical Sciences
JO  - Advances in Surgical Sciences
SP  - 9
EP  - 14
PB  - Science Publishing Group
SN  - 2376-6182
UR  - https://doi.org/10.11648/j.ass.20190701.13
AB  - Objective Investigating the surgical treatment for dysembryoplastic neuroepithelial tumor. Methods A total of 12 cases (7 males, 5 females, aged 4~36 years) of dysembryoplastic neuroepithelial tumors from 2010 to 2014 in Shanghai Blue Cross Brain Hospital were analyzed retrospectively, including 9 cases of temporal lobe tumor, 2 cases of frontal lobe tumor, and 1 case of parietal lobe tumor. The tumors and epileptogenic foci outside the lesions were resected under the guidance of electrocorticogram in all patients. Results The pathological examination showed that all the tumors were dysembryoplastic neuroepithelial tumors. All the patients had been followed up for 2 to 4 years. Epilepsy occurred in 2 patients and the others were seizure free after the surgery. No tumor recurrence occurred during the follow-up. Conclusion Dysembryoplastic neuroepithelial tumor is a benign tumor often causes intractable epilepsy, which can be controlled by the extended excision of the tumors and epileptogenic cortex under the guidance of electrocorticogram.
VL  - 7
IS  - 1
ER  -

Copy | Download